DP00043: Protein tonBFASTA viewXML view

General information
DisProt:DP00043
Name:Protein tonB
Synonym(s):TONB_ECOLI
First appeared in release:Release 3.0 (02/17/2006)
UniProt:P02929
UniGene: 
SwissProt: TONB_ECOLI
TrEMBL:  
NCBI (GI): 401196
Source organism:Escherichia coli (strain K12)
Sequence length:239
Percent disordered:21%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MTLDLPRRFP WPTLLSVCIH GAVVAGLLYT SVHQVIELPA PAQPISVTMV TPADLEPPQA - 60
VQPPPEPVVE PEPEPEPIPE PPKEAPVVIE KPKPKPKPKP KPVKKVQEQP KRDVKPVESR - 120
PASPFENTAP ARLTSSTATA ATSKPVTSVA SGPRALSRNQ PQYPARAQAL RIEGQVKVKF - 180
DVTPDGRVDN VQILSAKPAN MFEREVKNAM RRWRYEPGKP GSGIVVNILF KINGTTEIQ

Region 1: 103-151

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name:N-terminus of the C-terminal domain
Location:103 - 151
Length:49
Region sequence:

VKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVAS

Modification type: Fragment
Monomeric
PDB: 1XX3:A
Structural/functional type:  
Functional classes:  
Functional subclasses: Metal binding
Protein-protein binding
Detection methods:
  1. Nuclear magnetic resonance (NMR) (298 K; pH: 7; NaCl 100 mM; Tris 50 mM)
References:
  1. Peacock RS, Weljie AM, Howard SP, Price FD, and Vogel HJ. "The Solution Structure of the C-terminal Domain of TonB and Interaction Studies with TonB Box Peptides." J Mol Biol. 2005; 345(5): 1185-97. PubMed: 15644214
Comments:
 



References

  1. Postle K, Good RF. "DNA sequence of the Escherichia coli tonB gene." Proc Natl Acad Sci U S A. 1983; 80(17): 5235-9. PubMed: 6310567



Comments


The protein sequence referenced in the paper matches 98% with the Swiss-Prot sequence with discrepancies at amino acids 113, 159, 186 and an additional 5-amino acid initiation complex tagged at the beginning.


AV 6-28-2010 PubMed: 6310567


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