Annotation for this protein is in progress - please check future releases for more complete information



DP00162: StanninFASTA viewXML view

General information
DisProt:DP00162
Name:Stannin
Synonym(s):SNN_HUMAN
AG8_1
First appeared in release:Release 3.0 (02/17/2006)
UniProt:O75324
UniGene:Hs.700592
SwissProt: SNN_HUMAN
TrEMBL:  
NCBI (GI): 6094313
Source organism:Homo sapiens (Human)
Sequence length:88
Percent disordered:26%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MSIMDHSPTT GVVTVIVILI AIAALGALIL GCWCYLRLQR ISQSEDEESI VGDGETKEPF - 60
LLVQYSAKGP CVERKAKLMT PNGPEVHG

Region 1: 36-58

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:36 - 58
Length:23
Region sequence:

LRLQRISQSEDEESIVGDGETKE

Modification type: Monomeric
PDB:  
Structural/functional type: Function arises from the disordered state
Functional classes: Entropic chain
Functional subclasses: Flexible linkers/spacers
Detection methods:
  1. Nuclear magnetic resonance (NMR) (333 K; d25-SDS 600 mM; DTT (0.05-1 mM); H2O (10%); NaN3 (0.02%); Phosphate-buffered saline (pH 4.0) 20 mM)

References:
  1. Buck-Koehntop BA, Mascioni A, Buffy JJ, Veglia G. "Structure, dynamics, and membrane topology of stannin: a mediator of neuronal cell apoptosis induced by trimethyltin chloride." J Mol Biol. 2005; 354(3): 652-65. PubMed: 16246365

Comments:
 


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