Annotation for this protein is in progress - please check future releases for more complete information



DP00249: Troponin C, slow skeletal and cardiac musclesFASTA viewXML view

General information
DisProt:DP00249
Name:Troponin C, slow skeletal and cardiac muscles
Synonym(s):TNNC1_BOVIN
TN-C
First appeared in release:Release 3.0 (02/17/2006)
UniProt:P63315
UniGene:Bt.49083
SwissProt: TNNC1_BOVIN
TrEMBL:  
NCBI (GI): 54039740
Source organism:Bos taurus (Bovine)
Sequence length:161
Percent disordered:35%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MDDIYKAAVE QLTEEQKNEF KAAFDIFVLG AEDGCISTKE LGKVMRMLGQ NPTPEELQEM - 60
IDEVDEDGSG TVDFDEFLVM MVRCMKDDSK GKSEEELSDL FRMFDKNADG YIDLEELKIM - 120
LQATGETITE DDIEELMKDG DKNNDGRIDY DEFLEFMKGV E

Region 1: 103-158

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:103 - 158
Length:56
Region sequence:

MFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMK

Modification type:  
PDB:  
Structural/functional type: Function arises via a disorder to order transition
Functional classes:  
Functional subclasses: Metal binding
Protein-protein binding
Detection methods:
  1. Circular dichroism (CD) spectroscopy, far-UV (298 K; )

  2. Circular dichroism (CD) spectroscopy, near-UV (298 K; )

References:
  1. McCubbin WD, Kay CM. "Trypsin digestion of bovine cardiac troponin C in the presence and absence of calcium." Can J Biochem Cell Biol. 1985; 63(8): 812-23. PubMed: 2933134

Comments:
 



References

  1. van Eerd JP, Takahashi K. "The amino acid sequence of bovine cardiac tamponin-C. Comparison with rabbit skeletal troponin-C." Biochem Biophys Res Commun. 1975; 64(1): 122-7. PubMed: 1170846


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