Annotation for this protein is in progress - please check future releases for more complete information


DP00279: Olfactory marker proteinFASTA viewXML view

General information
DisProt:DP00279
Name:Olfactory marker protein
Synonym(s):OMP_RAT
Olfactory neuronal-specific protein
First appeared in release:Release 3.0 (02/17/2006)
UniProt:P08523
UniGene:Rn.9720
SwissProt: OMP_RAT
TrEMBL:  
NCBI (GI): 129096
Source organism:Rattus norvegicus (Rat)
Sequence length:163
Percent disordered:26%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MAEDGPQKQQ LDMPLVLDQD LTKQMRLRVE SLKQRGEKKQ DGEKLLRPAE SVYRLDFIQQ - 60
QKLQFDHWNV VLDKPGKVTI TGTSQNWTPD LTNLMTRQLL DPAAIFWRKE DSDAMDWNEA - 120
DALEFGERLS DLAKIRKVMY FLITFGEGVE PANLKASVVF NQL

Region 1: 35-49 Region 2: 57-68 Region 3: 84-99

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name:Loop 1
Location:35 - 49
Length:15
Region sequence:

RGEKKQDGEKLLRPA

Modification type:  
PDB:  
Structural/functional type:  
Functional classes:  
Functional subclasses:  
Detection methods:
  1. Nuclear magnetic resonance (NMR) (310 K; D2O 5 %; H2O 95 %; Na2EDTA 0.1 mM; Na2HPO4 (pH 6.6) 5 mM; NaN3 0.3 mM)
References:
  1. Gitti RK, Wright NT, Margolis JW, Varney KM, Weber DJ, Margolis FL. "Backbone Dynamics of the Olfactory Marker Protein As Studied by (15)N NMR Relaxation Measurements." Biochemistry. 2005; 44(28): 9673-9679. PubMed: 16008352
Comments:
 



Region 2
Type:Disordered
Name:Loop 2
Location:57 - 68
Length:12
Region sequence:

FIQQQKLQFDHW

Modification type:  
PDB:  
Structural/functional type:  
Functional classes:  
Functional subclasses:  
Detection methods:
  1. Nuclear magnetic resonance (NMR) (D2O 5 %; H2O 95 %; Na2EDTA 0.1 mM; Na2HPO4 (pH 6.6) 5 mM; NaN3 0.3 mM)
References:
  1. Gitti RK, Wright NT, Margolis JW, Varney KM, Weber DJ, Margolis FL. "Backbone Dynamics of the Olfactory Marker Protein As Studied by (15)N NMR Relaxation Measurements." Biochemistry. 2005; 44(28): 9673-9679. PubMed: 16008352
Comments:
 



Region 3
Type:Disordered
Name:Omega Loop
Location:84 - 99
Length:16
Region sequence:

SQNWTPDLTNLMTRQL

Modification type:  
PDB:  
Structural/functional type:  
Functional classes:  
Functional subclasses:  
Detection methods:
  1. Nuclear magnetic resonance (NMR) (D2O 5 %; H2O 95 %; Na2EDTA 0.1 mM; Na2HPO4 (pH 6.6) 5 %; NaN3 0.3 mM)
References:
  1. Gitti RK, Wright NT, Margolis JW, Varney KM, Weber DJ, Margolis FL. "Backbone Dynamics of the Olfactory Marker Protein As Studied by (15)N NMR Relaxation Measurements." Biochemistry. 2005; 44(28): 9673-9679. PubMed: 16008352
Comments:
 



References

  1. Baldisseri DM, Margolis JW, Weber DJ, Koo JH, Margolis FL. "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction." J Mol Biol. 2002; 319(3): 823-37. PubMed: 12054873


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