| General information | | DisProt: | DP00436 | | Name: | Canavalin | | Synonym(s): | CANA_CANEN
| | First appeared in release: | Release 3.0 (02/17/2006) | | UniProt: | P50477 | | UniGene: | | | SwissProt: | CANA_CANEN | | TrEMBL: | | | NCBI (GI): | 1705573 | | Source organism: | Canavalia ensiformis (Jack bean)(Horse bean) | | Sequence length: | 445 | | Percent disordered: | 21% | | Homologues: | |
| Native sequence |
10 20 30 40 50 60
| | | | | |
MAFSARFPLW LLLGVVLLAS VSASFAHSGH SGGEAEDESE ESRAQNNPYL FRSNKFLTLF - 60
KNQHGSLRLL QRFNEDTEKL ENLRDYRVLE YCSKPNTLLL PHHSDSDLLV LVLEGQAILV - 120
LVNPDGRDTY KLDQGDAIKI QAGTPFYLIN PDNNQNLRIL KFAITFRRPG TVEDFFLSST - 180
KRLPSYLSAF SKNFLEASYD SPYDEIEQTL LQEEQEGVIV KMPKDQIQEI SKHAQSSSRK - 240
TLSSQDKPFN LRSRDPIYSN NYGKLYEITP EKNSQLRDLD ILLNCLQMNE GALFVPHYNS - 300
RATVILVANE GRAEVELVGL EQQQQQGLES MQLRRYAATL SEGDIIVIPS SFPVALKAAS - 360
DLNMVGIGVN AENNERNFLA GHKENVIRQI PRQVSDLTFP GSGEEVEELL ENQKESYFVD - 420
GQPRHIDAGG KARRAHLPNL FRTFY
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| Functional narrative |
Seed storage protein.
|
| Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
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| Region 1 | | Type: | Disordered | | Name: | | | Location: | 1 - 45 | | Length: | 45 | | Region sequence: |
MAFSARFPLWLLLGVVLLASVSASFAHSGHSGGEAEDESEESRAQ | | Modification type: | Fragment
Native
| | PDB: | 2CAU:A, 2CAV:A | | Structural/functional type: | Relationship to function unknown
| | Functional classes: | Unknown
| | Functional subclasses: | Unknown
| Detection methods:
- X-ray crystallography (pH: 6.8; NaCl 2 %; phosphate (buffer) 0.05 M)
- Sensitivity to proteolysis
| References:
- Ko TP, Ng JD, McPherson A. "The three-dimensional structure of canavalin from jack bean (Canavalia ensiformis)." Plant Physiol. 1993; 101(3): 729-44. PubMed: 8310056
| Comments:
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| Region 2 | | Type: | Disordered | | Name: | | | Location: | 228 - 244 | | Length: | 17 | | Region sequence: |
QEISKHAQSSSRKTLSS | | Modification type: | Fragment
Native
| | PDB: | 2CAU:A, 2CAV:A | | Structural/functional type: | Relationship to function unknown
| | Functional classes: | Unknown
| | Functional subclasses: | Unknown
| Detection methods:
- X-ray crystallography (pH: 6.8; NaCl 2 %; phosphate (buffer) 0.05 M)
- Sensitivity to proteolysis
| References:
- Ko TP, Ng JD, McPherson A. "The three-dimensional structure of canavalin from jack bean (Canavalia ensiformis)." Plant Physiol. 1993; 101(3): 729-44. PubMed: 8310056
| Comments:
|
| Region 3 | | Type: | Disordered - Extended | | Name: | | | Location: | 320 - 333 | | Length: | 14 | | Region sequence: |
LEQQQQQGLESMQL | | Modification type: | Fragment
Native
| | PDB: | 2CAU:A, 2CAV:A | | Structural/functional type: | Relationship to function unknown
| | Functional classes: | Molecular assembly
| | Functional subclasses: | Protein-protein binding
| Detection methods:
- X-ray crystallography (pH: 6.8; NaCl 2 %; phosphate (buffer) 0.05 M)
- Sensitivity to proteolysis
| References:
- Ko TP, Ng JD, McPherson A. "The three-dimensional structure of canavalin from jack bean (Canavalia ensiformis)." Plant Physiol. 1993; 101(3): 729-44. PubMed: 8310056
| Comments:
|
| Region 4 | | Type: | Disordered | | Name: | | | Location: | 427 - 445 | | Length: | 19 | | Region sequence: |
DAGGKARRAHLPNLFRTFY | | Modification type: | Fragment
Native
| | PDB: | 2CAU:A, 2CAV:A | | Structural/functional type: | Relationship to function unknown
| | Functional classes: | Unknown
| | Functional subclasses: | Unknown
| Detection methods:
- X-ray crystallography (pH: 6.8; NaCl 2 %; phosphate (buffer) 0.05 M)
- Sensitivity to proteolysis
| References:
- Ko TP, Ng JD, McPherson A. "The three-dimensional structure of canavalin from jack bean (Canavalia ensiformis)." Plant Physiol. 1993; 101(3): 729-44. PubMed: 8310056
| Comments:
|
| References |
- Ng JD, Ko TP, McPherson A. "Cloning, expression, and crystallization of jack bean (Canavalia ensiformis) canavalin." Plant Physiol. 1993; 101(3): 713-28. PubMed: 8310055
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