General information | DisProt: | DP00006 | Name: | Cytochrome c | Synonym(s): | CYC_HORSE
Apocytochrome c
| First appeared in release: | Release 1.0 (08/01/2003) | UniProt: | P00004 | UniGene: | Eca.1571 | SwissProt: | CYC_HORSE | TrEMBL: | | NCBI (GI): | 119388048 | Source organism: | Equus caballus (Horse) | Sequence length: | 104 | Percent disordered: | 100% | Homologues: | |
Native sequence |
10 20 30 40 50 60 | | | | | | GDVEKGKKIF VQKCAQCHTV EKGGKHKTGP NLHGLFGRKT GQAPGFTYTD ANKNKGITWK - 60 EETLMEYLEN PKKYIPGTKM IFAGIKKKTE REDLIAYLKK ATNE
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Functional narrative |
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
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Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
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Region 1 | Type: | Disordered | Name: | | Location: | 1 - 104 | Length: | 104 | Region sequence: |
GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFTYTDANKNKGITWK EETLMEYLENPKKYIPGTKMIFAGIKKKTEREDLIAYLKKATNE | Modification type: | Fragment
Monomeric
| PDB: | | Structural/functional type: | | Functional classes: | | Functional subclasses: | Cofactor/heme binding
| Detection methods:
- Circular dichroism (CD) spectroscopy, far-UV (Cary model 60 (spectropolarimeter); extinction rate 2330 1/Mcm)
- Analytical ultracentrifugation (average V 0.744 mL/g; Sphinco Model E (analytical ultracentrifuge))
- Viscometry (296 K; Ostwald (capillary viscometer); outflow time 80 s)
| References:
- Stellwagen E, Rysavy R, Babul G. "The conformation of horse heart apocytochrome c." J Biol Chem. 1972; 247(24): 8074-7. PubMed: 4344990
| Comments:
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References |
- Stellwagen E, Rysavy R, Babul G. "The conformation of horse heart apocytochrome c." J Biol Chem. 1972; 247(24): 8074-7. PubMed: 4344990
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Comments |
Sent for AV (6-15-2010) PubMed: 4344990
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