This functional classification scheme was based on: Dunker AK, Brown CJ, Lawson JD, Iakoucheva LM, Obradovic Z. "Intrinsic disorder and protein function."Biochemistry. 2002 41(21):6573-82.
Regulates vesicle biogenesis in intracellular traffic; may modulate vesicle budding and uncoating within the Golgi apparatus; is involved in protein trafficking.
Entropic chain that forms a physical barrier around a target protein thereby reducing interactions that lead to aggregation, i.e. dessication tolerance provided by LEA proteins.