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DisProt Region Reference Corresponding author
DP00001Region 1Abramczyk D, Tchorzewski M, Krokowski D, Boguszewska A, Grankowski N. "Overexpression, purification and characterization of the acidic ribosomal P-proteins from Candida albicans." Biochim Biophys Acta. 2004; 1672(3): 214-23., PMID: 15182941  
DP00002 Remacha M, Saenz-Robles MT, Vilella MD, Ballesta JP. "Independent genes coding for three acidic proteins of the large ribosomal subunit from Saccharomyces cerevisiae." J Biol Chem. 1988; 263(19): 9094-9101., PMID: 2837476  
 Region 1Zurdo J, Sanz JM, Gonzalez C, Rico M, Ballesta JP. "The exchangeable yeast ribosomal acidic protein YP2beta shows characteristics of a partly folded state under physiological conditions." Biochemistry. 1997; 36(31): 9625-35., PMID: 9236009  
 Region 1Zurdo J, Gonzalez C, Sanz JM, Rico M, Remacha M, Ballesta JP. "Structural differences between Saccharomyces cerevisiae ribosomal stalk proteins P1 and P2 support their functional diversity." Biochemistry. 2000; 39(30): 8935-43., PMID: 10913306  
DP00003Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Tsernoglou D, Tsugita A, Tucker AD, van der Vliet PC. "Characterization of the chymotryptic core of the adenovirus DNA-binding protein." FEBS Lett. 1985; 188(2): 248-52., PMID: 4040872  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Tucker, P., Tsernoglou, D., Tucker, A., Coenjaerts, F., Leenders, H., Vliet, P. "Crystal structure of the adenovirus DNA binding protein reveals a hook-on model for cooperative DNA binding." 1994; 13(13): 2994-3002., PMID: 8039495  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Dekker J, Kanellopoulos PN, van Oosterhout JA, Stier G, Tucker PA, van der Vliet PC. "ATP-independent DNA unwinding by the adenovirus single-stranded DNA binding protein requires a flexible DNA binding loop." J Mol Biol. 1998; 277(4): 825-38., PMID: 9545375  
DP00004_C002Region 1Johansson J, Gudmundsson GH, Rottenberg ME, Berndt KD, Agerberth B. "Conformation-dependent antibacterial activity of the naturally occurring human peptide LL-37." J Biol Chem. 1998; 273(6): 3718-24., PMID: 9452503  
DP00005 Legault P, Li J, Mogridge J, Kay LE, Greenblatt J. "NMR structure of the bacteriophage lambda N peptide/boxB RNA complex: recognition of a GNRA fold by an arginine-rich motif." Cell. 1998; 93(2): 289-99., PMID: 9568720  
  Van Gilst MR, von Hippel PH. "Assembly of the N-dependent antitermination complex of phage lambda: NusA and RNA bind independently to different unfolded domains of the N protein." J Mol Biol. 1997; 274(2): 160-73., PMID: 9398524  
 Region 1Mogridge J, Legault P, Li J, Van Oene MD, Kay LE, Greenblatt J. "Independent ligand-induced folding of the RNA-binding domain and two functionally distinct antitermination regions in the phage lambda N protein." Mol Cell. 1998; 1(2): 265-75., PMID: 9659923  
DP00006 Stellwagen E, Rysavy R, Babul G. "The conformation of horse heart apocytochrome c." J Biol Chem. 1972; 247(24): 8074-7., PMID: 4344990  
 Region 1Stellwagen E, Rysavy R, Babul G. "The conformation of horse heart apocytochrome c." J Biol Chem. 1972; 247(24): 8074-7., PMID: 4344990  
DP00007 Barzilay G, Hickson ID. "Structure and function of apurinic/apyrimidinic endonucleases." Bioessays. 1995; 17(8): 713-9., PMID: 7661852  
  Robson CN, Hickson ID. "Isolation of cDNA clones encoding a human apurinic/apyrimidinic endonuclease that corrects DNA repair and mutagenesis defects in E. coli xth (exonuclease III) mutants." Nucleic Acids Res. 1991; 19(20): 5519-5523., PMID: 1719477  
  Robson CN, Hochhauser D, Craig R, Rack K, Buckle VJ, Hickson ID. "Structure of the human DNA repair gene HAP1 and its localisation to chromosome 14q 11.2-12." Nucleic Acids Res. 1992; 20(17): 4417-4421., PMID: 1383925  
 Region 1, Region 3, Region 4, Region 5Beernink PT, Segelke BW, Hadi MZ, Erzberger JP, Wilson DM 3rd, Rupp B. "Two divalent metal ions in the active site of a new crystal form of human apurinic/apyrimidinic endonuclease, Ape1: implications for the catalytic mechanism." J Mol Biol. 2001; 307(4): 1023-34., PMID: 11286553  
 Region 2, Region 6Gorman MA, Morera S, Rothwell DG, de La Fortelle E, Mol CD, Tainer JA, Hickson ID, Freemont PS. "The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites." Embo J. 1997; 16(21): 6548-58., PMID: 9351835  
DP00008 Chang JF, Phillips K, Lundback T, Gstaiger M, Ladbury JE, Luisi B. "Oct-1 POU and octamer DNA co-operate to recognise the Bob-1 transcription co-activator via induced folding." J Mol Biol. 1999; 288(5): 941-52., PMID: 10329190  
 Region 1Lee L, Stollar E, Chang J, Grossmann JG, O'Brien R, Ladbury J, Carpenter B, Roberts S, Luisi B. "Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator." Biochemistry. 2001; 40(22): 6580-8., PMID: 11380252  
 Region 1Chang JF, Phillips K, Lundback T, Gstaiger M, Ladbury JE, Luisi B. "Oct-1 POU and octamer DNA co-operate to recognise the Bob-1 transcription co-activator via induced folding." J Mol Biol. 1999; 288(5): 941-52., PMID: 10329190  
DP00009 Burley SK. "Picking up the TAB." Nature. 1996; 381(6578): 112-3., PMID: 8610004  
  Bleichenbacher M, Tan S, Richmond TJ. "Novel interactions between the components of human and yeast TFIIA/TBP/DNA complexes." J Mol Biol. 2003; 332(4): 783-93., PMID: 12972251  
 Region 1Tan S, Hunziker Y, Sargent DF, Richmond TJ. "Crystal structure of a yeast TFIIA/TBP/DNA complex." Nature. 1996; 381(6578): 127-51., PMID: 8610010  
DP00011 Bidwell LM, McManus ME, Gaedigk A, Kakuta Y, Negishi M, Pedersen L, Martin JL. "Crystal structure of human catecholamine sulfotransferase." J Mol Biol. 1999; 293(3): 521-30., PMID: 10543947  
  Dajani R, Cleasby A, Neu M, Wonacott AJ, Jhoti H, Hood AM, Modi S, Hersey A, Taskinen J, Cooke RM, Manchee GR, Coughtrie MW. "X-ray crystal structure of human dopamine sulfotransferase, SULT1A3. Molecular modeling and quantitative structure-activity relationship analysis demonstrate a molecular basis for sulfotransferase substrate specificity." J Biol Chem. 1999; 274(53): 37862-8., PMID: 10608851  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10Bidwell LM, McManus ME, Gaedigk A, Kakuta Y, Negishi M, Pedersen L, Martin JL. "Crystal structure of human catecholamine sulfotransferase." J Mol Biol. 1999; 293(3): 521-30., PMID: 10543947  
DP00012 Ostedgaard LS, Baldursson O, Vermeer DW, Welsh MJ, Robertson AD. "A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution." Proc Natl Acad Sci U S A. 2000; 97(10): 5657-62., PMID: 10792060  
 Region 1Ostedgaard LS, Baldursson O, Vermeer DW, Welsh MJ, Robertson AD. "A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution." Proc Natl Acad Sci U S A. 2000; 97(10): 5657-62., PMID: 10792060  
DP00013 Lapthorn AJ, Harris DC, Littlejohn A, Lustbader JW, Canfield RE, Machin KJ, Morgan FJ, Isaacs NW. "Crystal structure of human chorionic gonadotropin." Nature. 1994; 369(6480): 455-61., PMID: 8202136  
 Region 1Lapthorn AJ, Harris DC, Littlejohn A, Lustbader JW, Canfield RE, Machin KJ, Morgan FJ, Isaacs NW. "Crystal structure of human chorionic gonadotropin." Nature. 1994; 369(6480): 455-61., PMID: 8202136  
DP00014 Barghorn S, Davies P, Mandelkow E. "Tau paired helical filaments from Alzheimer's disease brain and assembled in vitro are based on beta-structure in the core domain." Biochemistry. 2004; 43(6): 1694-703., PMID: 14769047 mand@mpasmb.desy.de
  Tsuruta JK, Wong K, Fritz IB, Griswold MD. "Structural analysis of sulphated glycoprotein 2 from amino acid sequence. Relationship to clusterin and serum protein 40,40." Biochem J. 1990; 268(3): 571-8., PMID: 2363694  
 Region 1, Region 2, Region 3Bailey RW, Dunker AK, Brown CJ, Garner EC, Griswold MD. "Clusterin, a binding protein with a molten globule-like region." Biochemistry. 2001; 40(39): 11828-40., PMID: 11570883  
DP00015 Knighton DR, Zheng JH, Ten Eyck LF, Xuong NH, Taylor SS, Sowadski JM. "Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase." Science. 1991; 253(5018): 414-20., PMID: 1862343  
  Thomas J, Van Patten SM, Howard P, Day KH, Mitchell RD, Sosnick T, Trewhella J, Walsh DA, Maurer RA. "Expression in Escherichia coli and characterization of the heat-stable inhibitor of the cAMP-dependent protein kinase." J Biol Chem. 1991; 266(17): 10906-11., PMID: 2040607  
 Region 1Knighton DR, Zheng JH, Ten Eyck LF, Xuong NH, Taylor SS, Sowadski JM. "Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase." Science. 1991; 253(5018): 414-20., PMID: 1862343  
 Region 1Thomas J, Van Patten SM, Howard P, Day KH, Mitchell RD, Sosnick T, Trewhella J, Walsh DA, Maurer RA. "Expression in Escherichia coli and characterization of the heat-stable inhibitor of the cAMP-dependent protein kinase." J Biol Chem. 1991; 266(17): 10906-11., PMID: 2040607  
DP00016 Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ. "The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases." Cell. 1993; 75(4): 805-16., PMID: 8242751  
 Region 1Kriwacki RW, Hengst L, Tennant L, Reed SI, Wright PE. "Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity." Proc Natl Acad Sci U S A. 1996; 93(21): 11504-9., PMID: 8876165  
 Region 1Kriwacki RW, Wu J, Tennant L, Wright PE, Siuzdak G. "Probing protein structure using biochemical and biophysical methods. Proteolysis, matrix-assisted laser desorption/ionization mass spectrometry, high-performance liquid chromatography and size-exclusion chromatography of p21Waf1/Cip1/Sdi1." J Chromatogr A. 1997; 777(1): 23-30., PMID: 9297835  
DP00017Region 1, Region 2Adkins JN, Lumb KJ. "Intrinsic structural disorder and sequence features of the cell cycle inhibitor p57Kip2." Proteins. 2002; 46(1): 1-7., PMID: 11746698  
 Region 1, Region 2Dynlacht BD, Ngwu C, Winston J, Swindell EC, Elledge SJ, Harlow E, Harper JW. "Purification and analysis of CIP/KIP proteins." Methods Enzymol. 1997; 283: 230-44., PMID: 9251023  
DP00018 Lacy ER, Filippov I, Lewis WS, Otieno S, Xiao L, Weiss S, Hengst L, Kriwacki RW. "p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding." Nat Struct Mol Biol. 2004; 11(4): 358-64., PMID: 15024385  
 Region 1, Region 2Lacy ER, Filippov I, Lewis WS, Otieno S, Xiao L, Weiss S, Hengst L, Kriwacki RW. "p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding." Nat Struct Mol Biol. 2004; 11(4): 358-64., PMID: 15024385  
 Region 1Russo AA, Jeffrey PD, Patten AK, Massague J, Pavletich NP. "Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex." Nature. 1996; 382(6589): 325-31., PMID: 8684460  
DP00020 Konig P, Giraldo R, Chapman L, Rhodes D. "The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA." Cell. 1996; 85(1): 125-36., PMID: 8620531  
 Region 1, Region 2Konig P, Giraldo R, Chapman L, Rhodes D. "The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA." Cell. 1996; 85(1): 125-36., PMID: 8620531  
DP00021 AEvarsson A, Brazhnikov E, Garber M, Zheltonosova J, Chirgadze Y, al-Karadaghi S, Svensson LA, Liljas A. "Three-dimensional structure of the ribosomal translocase: elongation factor G from Thermus thermophilus." EMBO J. 1994; 13(16): 3669-77., PMID: 8070397  
  Laurberg M, Kristensen O, Martemyanov K, Gudkov AT, Nagaev I, Hughes D, Liljas A. "Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site." J Mol Biol. 2000; 303(4): 593-603., PMID: 11054294  
 Region 2AEvarsson A, Brazhnikov E, Garber M, Zheltonosova J, Chirgadze Y, al-Karadaghi S, Svensson LA, Liljas A. "Three-dimensional structure of the ribosomal translocase: elongation factor G from Thermus thermophilus." EMBO J. 1994; 13(16): 3669-77., PMID: 8070397  
 Region 1, Region 2Laurberg M, Kristensen O, Martemyanov K, Gudkov AT, Nagaev I, Hughes D, Liljas A. "Structure of a mutant EF-G reveals domain III and possibly the fusidic acid binding site." J Mol Biol. 2000; 303(4): 593-603., PMID: 11054294  
DP00022 Eom J, Baker WR, Kintanar A, Wurtele ES. "The embryo-specific EMB-1 protein of Daucus carota is flexible and unstructured in solution." Plant Science. 1996; 115: 17-24. 
 Region 1Eom J, Baker WR, Kintanar A, Wurtele ES. "The embryo-specific EMB-1 protein of Daucus carota is flexible and unstructured in solution." Plant Science. 1996; 115: 17-24. 
 Region 1Ulrich TU, Wurtele ES, Nikolau BJ. "Sequence of EMB-1, an mRNA accumulating specifically in embryos of carrot." Nucleic Acids Res.. 1990; 18(9): 2826., PMID: 2339072  
DP00023Region 1, Region 17Sawicki MW, Erman M, Puranen T, Vihko P, Ghosh D. "Structure of the ternary complex of human 17beta-hydroxysteroid dehydrogenase type 1 with 3-hydroxyestra-1,3,5,7-tetraen-17-one (equilin) and NADP+." Proc Natl Acad Sci U S A. 1999; 96(3): 840-845., PMID: 9927655  
 Region 1, Region 18Han Q, Campbell RL, Gangloff A, Huang YW, Lin SX. "Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain." J Biol Chem. 2000; 275(2): 1105-1111., PMID: 10625652  
 Region 5, Region 10, Region 11, Region 12, Region 13, Region 14, Region 15, Region 16Mazza C, Breton R, Housset D, Fontecilla-Camps JC. "Unusual charge stabilization of NADP+ in 17beta-hydroxysteroid dehydrogenase." J Biol Chem. 1998; 273(14): 8145-8152., PMID: 9525918  
 Region 1, Region 2Azzi A, Rehse PH, Zhu DW, Campbell RL, Labrie F, Lin SX. "Crystal structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase complexed with 17 beta-estradiol." Nat Struct Biol. 1996; 3(8): 665-8., PMID: 8756321  
 Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9Breton R, Housset D, Mazza C, Fontecilla-Camps JC. "The structure of a complex of human 17beta-hydroxysteroid dehydrogenase with estradiol and NADP+ identifies two principal targets for the design of inhibitors." Structure. 1996; 4(8): 905-15., PMID: 8805577  
 Region 5, Region 19Gangloff A, Shi R, Nahoum V, Lin SX. "Pseudo-symmetry of C19 steroids, alternative binding orientations, and multispecificity in human estrogenic 17beta-hydroxysteroid dehydrogenase." Faseb J. 2003; 17(2): 274-276., PMID: 12490543  
 Region 1Ghosh D, Pletnev VZ, Zhu DW, Wawrzak Z, Duax WL, Pangborn W, Labrie F, Lin SX. "Structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase at 2.20 A resolution." Structure. 1995; 3(5): 503-513., PMID: 7663947  
 Region 5Qiu W, Campbell RL, Gangloff A, Dupuis P, Boivin RP, Tremblay MR, Poirier D, Lin SX. "A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity." Faseb J. 2002; 16(13): 1829-1831., PMID: 12223444  
DP00024 Chemes LB, Sanchez IE, Smal C, de Prat-Gay G. "Targeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein." FEBS J. ., PMID: 20088881  
 Region 1Pahel G, Aulabaugh A, Short SA, Barnes JA, Painter GR, Ray P, Phelps WC. "Structural and functional characterization of the HPV16 E7 protein expressed in bacteria." J Biol Chem. 1993; 268(34): 26018-25., PMID: 8245034  
DP00025 Penkett CJ, Redfield C, Dodd I, Hubbard J, McBay DL, Mossakowska DE, Smith RA, Dobson CM, Smith LJ. "NMR analysis of main-chain conformational preferences in an unfolded fibronectin-binding protein." J Mol Biol. 1997; 274(2): 152-9., PMID: 9398523  
 Region 1Penkett CJ, Redfield C, Dodd I, Hubbard J, McBay DL, Mossakowska DE, Smith RA, Dobson CM, Smith LJ. "NMR analysis of main-chain conformational preferences in an unfolded fibronectin-binding protein." J Mol Biol. 1997; 274(2): 152-9., PMID: 9398523  
DP00026 Vonderviszt F, Kanto S, Aizawa S, Namba K. "Terminal regions of flagellin are disordered in solution." J Mol Biol. 1989; 209(1): 127-33., PMID: 2810365  
 Region 1, Region 2Vonderviszt F, Kanto S, Aizawa S, Namba K. "Terminal regions of flagellin are disordered in solution." J Mol Biol. 1989; 209(1): 127-33., PMID: 2810365  
DP00027 Daughdrill GW, Chadsey MS, Karlinsey JE, Hughes KT, Dahlquist FW. "The C-terminal half of the anti-sigma factor, FlgM, becomes structured when bound to its target, sigma 28." Nat Struct Biol. 1997; 4(4): 285-91., PMID: 9095196  
 Region 1Daughdrill GW, Chadsey MS, Karlinsey JE, Hughes KT, Dahlquist FW. "The C-terminal half of the anti-sigma factor, FlgM, becomes structured when bound to its target, sigma 28." Nat Struct Biol. 1997; 4(4): 285-91., PMID: 9095196  
DP00028 Fletcher CM, Wagner G. "The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein." Protein Sci. 1998; 7(7): 1639-42., PMID: 9684899  
 Region 1Fletcher CM, Wagner G. "The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein." Protein Sci. 1998; 7(7): 1639-42., PMID: 9684899  
DP00029 Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F. "GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons." Science. 1993; 260(5111): 1130-2., PMID: 8493557  
 Region 1, Region 2Eketjäll S, Fainzilber M, Murray-Rust J, Ibáñez CF. "Distinct structural elements in GDNF mediate binding to GFRalpha1 and activation of the GFRalpha1-c-Ret receptor complex." EMBO J. 1999; 18(21): 5901-10., PMID: 10545102  
 Region 1, Region 3, Region 4Eigenbrot C, Gerber N. "X-ray structure of glial cell-derived neurotrophic factor at 1.9 A resolution and implications for receptor binding." Nat Struct Biol. 1997; 4(6): 435-8., PMID: 9187648  
DP00030 Hollenberg SM, Weinberger C, Ong ES, Cerelli G, Oro A, Lebo R, Thompson EB, Rosenfeld MG, Evans RM. "Primary structure and expression of a functional human glucocorticoid receptor cDNA." Nature. 1985; 318(6047): 635-41., PMID: 2867473  
  Garza AM, Khan SH, Kumar R. "Site-Specific Phosphorylation Induces Functionally Active Conformation in the Intrinsically Disordered N-Terminal Activation Function (AF1) Domain of the Glucocorticoid Receptor." Mol Cell Biol. 2010; 30(1): 220-30., PMID: 19841061  
 Region 1, Region 2Baskakov IV, Kumar R, Srinivasan G, Ji YS, Bolen DW, Thompson EB. "Trimethylamine N-oxide-induced cooperative folding of an intrinsically unfolded transcription-activating fragment of human glucocorticoid receptor." J Biol Chem. 1999; 274(16): 10693-6., PMID: 10196139 bthompso@utmb.edu
 Region 1Dahlman-Wright K, Baumann H, McEwan IJ, Almlöf T, Wright AP, Gustafsson JA, Härd T. "Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor." Proc Natl Acad Sci U S A. 1995; 92(5): 1699-1703., PMID: 7878043  
 Region 1Li G, Wang S, Gelehrter TD. "Identification of glucocorticoid receptor domains involved in transrepression of transforming growth factor-beta action." J Biol Chem. 2003; 278(43): 41779-41788., PMID: 12902338  
DP00031 Huang Y, Komoto J, Konishi K, Takata Y, Ogawa H, Gomi T, Fujioka M, Takusagawa F. "Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes." J Mol Biol. 2000; 298(1): 149-62., PMID: 10756111  
 Region 1Huang Y, Komoto J, Konishi K, Takata Y, Ogawa H, Gomi T, Fujioka M, Takusagawa F. "Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes." J Mol Biol. 2000; 298(1): 149-62., PMID: 10756111  
DP00032 Mazauric MH, Keith G, Logan D, Kreutzer R, Giege R, Kern D. "Glycyl-tRNA synthetase from Thermus thermophilus--wide structural divergence with other prokaryotic glycyl-tRNA synthetases and functional inter-relation with prokaryotic and eukaryotic glycylation systems." Eur J Biochem. 1998; 251(3): 744-57., PMID: 9490048  
 Region 1Arnez JG, Dock-Bregeon AC, Moras D. "Glycyl-tRNA synthetase uses a negatively charged pit for specific recognition and activation of glycine." J Mol Biol. 1999; 286(5): 1449-59., PMID: 10064708  
 Region 1Logan DT, Mazauric MH, Kern D, Moras D. "Crystal structure of glycyl-tRNA synthetase from Thermus thermophilus." Embo J. 1995; 14(17): 4156-67., PMID: 7556056  
DP00033_C001 Clackson T, Wells JA. "A hot spot of binding energy in a hormone-receptor interface." Science. 1995; 267(5196): 383-6., PMID: 7529940  
  Clackson T, Ultsch MH, Wells JA, de Vos AM. "Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity." J Mol Biol. 1998; 277(5): 1111-28., PMID: 9571026  
  Fuh G, Mulkerrin MG, Bass S, McFarland N, Brochier M, Bourell JH, Light DR, Wells JA. "The human growth hormone receptor. Secretion from Escherichia coli and disulfide bonding pattern of the extracellular binding domain." J Biol Chem. 1990; 265(6): 3111-3115., PMID: 2406245  
  de Vos AM, Ultsch M, Kossiakoff AA. "Human growth hormone and extracellular domain of its receptor: crystal structure of the complex." Science. 1992; 255(5042): 306-312., PMID: 1549776  
  Sundstrom M, Lundqvist T, Rodin J, Giebel LB, Milligan D, Norstedt G. "Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution." J Biol Chem. 1996; 271(50): 32197-32203., PMID: 8943276  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 11, Region 12Clackson T, Ultsch MH, Wells JA, de Vos AM. "Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity." J Mol Biol. 1998; 277(5): 1111-28., PMID: 9571026  
 Region 5, Region 6, Region 13, Region 14, Region 15, Region 16, Region 17, Region 18de Vos AM, Ultsch M, Kossiakoff AA. "Human growth hormone and extracellular domain of its receptor: crystal structure of the complex." Science. 1992; 255(5042): 306-312., PMID: 1549776  
 Region 7, Region 8, Region 9, Region 10Sundstrom M, Lundqvist T, Rodin J, Giebel LB, Milligan D, Norstedt G. "Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution." J Biol Chem. 1996; 271(50): 32197-32203., PMID: 8943276  
DP00034 Nilsson N, Malmborg AC, Borrebaeck CA. "The phage infection process: a functional role for the distal linker region of bacteriophage protein 3." J Virol. 2000; 74(9): 4229-35., PMID: 10756036  
 Region 1Holliger P, Riechmann L, Williams RL. "Crystal structure of the two N-terminal domains of g3p from filamentous phage fd at 1.9 A: evidence for conformational lability." J Mol Biol. 1999; 288(4): 649-57., PMID: 10329170  
 Region 1Nilsson N, Malmborg AC, Borrebaeck CA. "The phage infection process: a functional role for the distal linker region of bacteriophage protein 3." J Virol. 2000; 74(9): 4229-35., PMID: 10756036  
DP00035 Coleman DE, Berghuis AM, Lee E, Linder ME, Gilman AG, Sprang SR. "Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis." Science. 1994; 265(5177): 1405-12., PMID: 8073283  
 Region 1, Region 2Coleman DE, Berghuis AM, Lee E, Linder ME, Gilman AG, Sprang SR. "Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis." Science. 1994; 265(5177): 1405-12., PMID: 8073283  
DP00036 Jakobsen BK, Pelham HR. "A conserved heptapeptide restrains the activity of the yeast heat shock transcription factor." Embo J. 1991; 10(2): 369-75., PMID: 1899375  
 Region 1Cho HS, Liu CW, Damberger FF, Pelton JG, Nelson HC, Wemmer DE. "Yeast heat shock transcription factor N-terminal activation domains are unstructured as probed by heteronuclear NMR spectroscopy." Protein Sci. 1996; 5(2): 262-9., PMID: 8745404  
 Region 2, Region 3Damberger FF, Pelton JG, Harrison CJ, Nelson HC, Wemmer DE. "Solution structure of the DNA-binding domain of the heat shock transcription factor determined by multidimensional heteronuclear magnetic resonance spectroscopy." Protein Sci. 1994; 3(10): 1806-21., PMID: 7849597  
 Region 4Harrison CJ, Bohm AA, Nelson HC. "Crystal structure of the DNA binding domain of the heat shock transcription factor." Science. 1994; 263(5144): 224-7., PMID: 8284672  
DP00037 Mizohata E, Sakai H, Fusatomi E, Terada T, Murayama K, Shirouzu M, Yokoyama S. "Crystal Structure of an Archaeal Peroxiredoxin from the Aerobic Hyperthermophilic Crenarchaeon Aeropyrum pernix K1." J Mol Biol. 2005., PMID: 16214169  
 Region 1, Region 2, Region 3, Region 4, Region 5Mizohata E, Sakai H, Fusatomi E, Terada T, Murayama K, Shirouzu M, Yokoyama S. "Crystal Structure of an Archaeal Peroxiredoxin from the Aerobic Hyperthermophilic Crenarchaeon Aeropyrum pernix K1." J Mol Biol. 2005., PMID: 16214169  
DP00038Region 1Cary PD, Crane-Robinson C, Bradbury EM, Dixon GH. "Structural studies of the non-histone chromosomal proteins HMG-T and H6 from trout testis." Eur J Biochem. 1981; 119(3): 545-51., PMID: 6273163  
DP00039Region 1Abercrombie BD, Kneale GG, Crane-Robinson C, Bradbury EM, Goodwin GH, Walker JM, Johns EW. "Studies on the conformational properties of the high-mobility-group chromosomal protein HMG 17 and its interaction with DNA." Eur J Biochem. 1978; 84(1): 173-7., PMID: 565710  
DP00040Region 1Munshi N, Agalioti T, Lomvardas S, Merika M, Chen G, Thanos D. "Coordination of a transcriptional switch by HMGI(Y) acetylation." Science. 2001; 293(5532): 1133-1136., PMID: 11498590  
 Region 1Pierantoni GM, Fedele M, Pentimalli F, Benvenuto G, Pero R, Viglietto G, Santoro M, Chiariotti L, Fusco A. "High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth." Oncogene. 2001; 20(43): 6132-6141., PMID: 11593421  
 Region 1Wang, D. Z. Ray, P. Boothby, M. "Interleukin 4-inducible phosphorylation of HMG-I(Y) is inhibited by rapamycin." J Biol Chem. 1995; 270(39): 22924-22932., PMID: 7559428  
 Region 1Reeves, R. Nissen, M. S. "Purification and assays for high mobility group HMG-I(Y) protein function." Methods of Enzymology. 1996; 304: 155-188., PMID: 10372360  
DP00041 Pentecost BT, Wright JM, Dixon GH. "Isolation and sequence of cDNA clones coding for a member of the family of high mobility group proteins (HMG-T) in trout and analysis of HMG-T-mRNA's in trout tissues." Nucleic Acids Res. 1985; 13(13): 4871-4888., PMID: 4022777  
  Watson DC, Peters EH, Dixon GH. "The purification, characterization and partial sequence determination of a trout testis non-histone protein, HMG-T." Eur J Biochem. 1977; 74(1): 53-60., PMID: 852459  
  Watson DC, Dixon GH. "Amino acid sequence homologies between the high-mobility-group proteins, HMG-T from trout testis and HMG-1 and -2 from calf thymus: is the poly-aspartic-glutamic acid polypeptide within the main chain?" Biosci Rep. 1981; 1(2): 167-175., PMID: 6117336  
  Cary PD, Crane-Robinson C, Bradbury EM, Dixon GH. "Structural studies of the non-histone chromosomal proteins HMG-T and H6 from trout testis." Eur J Biochem. 1981; 119(3): 545-51., PMID: 6273163  
  Stros M, Nishikawa S, Dixon GH. "cDNA sequence and structure of a gene encoding trout testis high-mobility-group-1 protein." Eur J Biochem. 1994; 225(2): 581-91., PMID: 7957172  
 Region 1Cary PD, Crane-Robinson C, Bradbury EM, Dixon GH. "Structural studies of the non-histone chromosomal proteins HMG-T and H6 from trout testis." Eur J Biochem. 1981; 119(3): 545-51., PMID: 6273163  
DP00042Region 1Cary PD, Crane-Robinson C, Bradbury EM, Dixon GH. "Structural studies of the non-histone chromosomal proteins HMG-T and H6 from trout testis." Eur J Biochem. 1981; 119(3): 545-51., PMID: 6273163  
DP00043 Postle K, Good RF. "DNA sequence of the Escherichia coli tonB gene." Proc Natl Acad Sci U S A. 1983; 80(17): 5235-9., PMID: 6310567  
 Region 1Peacock RS, Weljie AM, Howard SP, Price FD, and Vogel HJ. "The Solution Structure of the C-terminal Domain of TonB and Interaction Studies with TonB Box Peptides." J Mol Biol. 2005; 345(5): 1185-97., PMID: 15644214  
DP00044 Ramakrishnan V, Finch JT, Graziano V, Lee PL, Sweet RM. "Crystal structure of globular domain of histone H5 and its implications for nucleosome binding." Nature. 1993; 362(6417): 219-223., PMID: 8384699  
 Region 1, Region 2, Region 3Graziano, V. Gerchman, S. E. Wonacott, A. J. Sweet, R. M. Wells, J. R. White, S. W. Ramakrishnan, V. "Crystallization of the globular domain of histone H5." J Mol Biol. 1990; 212(2): 253-257., PMID: 2181148  
DP00045Region 1, Region 2Focia PJ, Craig SP 3rd, Nieves-Alicea R, Fletterick RJ, Eakin AE. "A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi." Biochemistry. 1998; 37(43): 15066-15075., PMID: 9790669  
DP00046 Kobielak K, Kobielak A, Trzeciak WH. "Cloning of the lymphoid enhancer binding factor-1 (Lef-1) cDNA from rat kidney: homology to the mouse sequence." Acta Biochim Pol. 1999; 46(4): 885-888., PMID: 10824856  
 Region 1Love JJ, Li X, Case DA, Giese K, Grosschedl R, Wright PE. "Structural basis for DNA bending by the architectural transcription factor LEF-1." Nature. 1995; 376(6543): 791-795., PMID: 7651541  
DP00047Region 1Polverini, E. Fasano, A. Zito, F. Riccio, P. Cavatorta, P. "Conformation of bovine myelin basic protein purified with bound lipids." Eur Biophys J. 1999; 28(4): 351-355., PMID: 10394626  
DP00048Region 4, Region 5, Region 6, Region 7Arold ST, Baur AS. "Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein." Trends Biochem Sci. 2001; 26(6): 356-63., PMID: 11406408  
 Region 1, Region 2, Region 3Arold S, Franken P, Strub MP, Hoh F, Benichou S, Benarous R, Dumas C. "The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling." Structure. 1997; 5(10): 1361-72., PMID: 9351809  
DP00049 Jiang Y, Yu VC, Buchholz F, O'Connell S, Rhodes SJ, Candeloro C, Xia YR, Lusis AJ, Rosenfeld MG. "A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland." J Biol Chem. 1996; 271(18): 10723-10730., PMID: 8631881  
 Region 1Berkovits HJ, Berg JM. "Metal and DNA binding properties of a two-domain fragment of neural zinc finger factor 1, a CCHC-type zinc binding protein." Biochemistry. 1999; 38(51): 16826-30., PMID: 10606515  
DP00050Region 1Julien JP, Cote F, Beaudet L, Sidky M, Flavell D, Grosveld F, Mushynski W. "Sequence and structure of the mouse gene coding for the largest neurofilament subunit." Gene. 1988; 68(2): 307-314., PMID: 3220257  
 Region 1Brown HG, Hoh JH. "Entropic exclusion by neurofilament sidearms: a mechanism for maintaining interfilament spacing." Biochemistry. 1997; 36(49): 15035-40., PMID: 9424114  
 Region 1Hoh JH. "Functional protein domains from the thermally driven motion of polypeptide chains: a proposal." Proteins. 1998; 32(2): 223-8., PMID: 9714161  
DP00051Region 5, Region 6, Region 7, Region 8Jackson LK, Brooks HB, Osterman AL, Goldsmith EJ, Phillips MA. "Altering the reaction specificity of eukaryotic ornithine decarboxylase." Biochemistry. 2000; 39(37): 11247-11257., PMID: 10985770  
 Region 1, Region 2, Region 3, Region 4Jancarik J, Kim SH. "Sparse matrix sampling: a screening method for crystallization of proteins." J Appl Cryst. 1991; 24(Pt. 4): 409-11. 
 Region 1, Region 2, Region 3, Region 4Grishin NV, Osterman AL, Brooks HB, Phillips MA, Goldsmith EJ. "X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine." Biochemistry. 1999; 38(46): 15174-15184., PMID: 10563800  
DP00052Region 1Engel J, Taylor W, Paulsson M, Sage H, Hogan B. "Calcium binding domains and calcium-induced conformational transition of SPARC/BM-40/osteonectin, an extracellular glycoprotein expressed in mineralized and nonmineralized tissues." Biochemistry. 1987; 26(22): 6958-65., PMID: 3427055  
DP00053 Mosyak L, Reshetnikova L, Goldgur Y, Delarue M, Safro MG. "Structure of phenylalanyl-tRNA synthetase from Thermus thermophilus." Nat Struct Biol. 1995; 2(7): 537-47., PMID: 7664121  
 Region 1Goldgur Y, Mosyak L, Reshetnikova L, Ankilova V, Lavrik O, Khodyreva S, Safro M. "The crystal structure of phenylalanyl-tRNA synthetase from thermus thermophilus complexed with cognate tRNAPhe." Structure. 1997; 5(1): 59-68., PMID: 9016717  
 Region 1Mosyak L, Reshetnikova L, Goldgur Y, Delarue M, Safro MG. "Structure of phenylalanyl-tRNA synthetase from Thermus thermophilus." Nat Struct Biol. 1995; 2(7): 537-47., PMID: 7664121  
DP00054 Castellino AM, Parker GJ, Boronenkov IV, Anderson RA, Chao MV. "A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase." J Biol Chem. 1997; 272(9): 5861-70., PMID: 9038203  
 Region 1, Region 2, Region 3, Region 4Rao VD, Misra S, Boronenkov IV, Anderson RA, Hurley JH. "Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation." Cell. 1998; 94(6): 829-839., PMID: 9753329  
DP00055 Essen LO, Perisic O, Cheung R, Katan M, Williams RL. "Crystal structure of a mammalian phosphoinositide-specific phospholipase C delta." Nature. 1996; 380(6575): 595-602., PMID: 8602259  
  Grobler JA, Essen LO, Williams RL, Hurley JH. "C2 domain conformational changes in phospholipase C-delta 1." Nat Struct Biol. 1996; 3(9): 788-95., PMID: 8784353  
 Region 5, Region 6Essen LO, Perisic O, Cheung R, Katan M, Williams RL. "Crystal structure of a mammalian phosphoinositide-specific phospholipase C delta." Nature. 1996; 380(6575): 595-602., PMID: 8602259  
 Region 1, Region 2, Region 3, Region 4, Region 7Grobler JA, Essen LO, Williams RL, Hurley JH. "C2 domain conformational changes in phospholipase C-delta 1." Nat Struct Biol. 1996; 3(9): 788-95., PMID: 8784353  
DP00057Region 1Gatewood JM, Schroth GP, Schmid CW, Bradbury EM. "Zinc-induced secondary structure transitions in human sperm protamines." J Biol Chem. 1990; 265(33): 20667-72., PMID: 2243113  
 Region 1Nakano M, Kasai K, Yoshida K, Tanimoto T, Tamaki Y, Tobita T. "Conformation of the fowl protamine, galline, and its binding properties to DNA." J Biochem (Tokyo). 1989; 105(1): 133-7., PMID: 2738040  
DP00058 Gast K, Damaschun H, Eckert K, Schulze-Forster K, Maurer HR, Muller-Frohne M, Zirwer D, Czarnecki J, Damaschun G. "Prothymosin alpha: a biologically active protein with random coil conformation." Biochemistry. 1995; 34(40): 13211-8., PMID: 7548085  
 Region 1Gast K, Damaschun H, Eckert K, Schulze-Forster K, Maurer HR, Muller-Frohne M, Zirwer D, Czarnecki J, Damaschun G. "Prothymosin alpha: a biologically active protein with random coil conformation." Biochemistry. 1995; 34(40): 13211-8., PMID: 7548085  
DP00060 Gong W, O'Gara M, Blumenthal RM, Cheng X. "Structure of pvu II DNA-(cytosine N4) methyltransferase, an example of domain permutation and protein fold assignment." Nucleic Acids Res. 1997; 25(14): 2702-15., PMID: 9207015  
 Region 1, Region 2Gong W, O'Gara M, Blumenthal RM, Cheng X. "Structure of pvu II DNA-(cytosine N4) methyltransferase, an example of domain permutation and protein fold assignment." Nucleic Acids Res. 1997; 25(14): 2702-15., PMID: 9207015  
DP00061 Jacobs DM, Lipton AS, Isern NG, Daughdrill GW, Lowry DF, Gomes X, Wold MS. "Human replication protein A: global fold of the N-terminal RPA-70 domain reveals a basic cleft and flexible C-terminal linker." J Biomol NMR. 1999; 14(4): 321-31., PMID: 10526407  
 Region 1Jacobs DM, Lipton AS, Isern NG, Daughdrill GW, Lowry DF, Gomes X, Wold MS. "Human replication protein A: global fold of the N-terminal RPA-70 domain reveals a basic cleft and flexible C-terminal linker." J Biomol NMR. 1999; 14(4): 321-31., PMID: 10526407  
DP00062 Mangelsdorf DJ, Ong ES, Dyck JA, Evans RM. "Nuclear receptor that identifies a novel retinoic acid response pathway." Nature. 1990; 345(6272): 224-9., PMID: 2159111  
 Region 1, Region 2, Region 3, Region 4, Region 5Holmbeck SM, Foster MP, Casimiro DR, Sem DS, Dyson HJ, Wright PE. "High-resolution solution structure of the retinoid X receptor DNA-binding domain." J Mol Biol. 1998; 281(2): 271-84., PMID: 9698548  
 Region 1, Region 2, Region 3, Region 4, Region 5Holmbeck SM, Dyson HJ, Wright PE. "DNA-induced conformational changes are the basis for cooperative dimerization by the DNA binding domain of the retinoid X receptor." J Mol Biol. 1998; 284(3): 533-9., PMID: 9826495  
DP00063 Chatterjee TK, Fisher RA. "Novel alternative splicing and nuclear localization of human RGS12 gene products." J Biol Chem. 2000; 275(38): 29660-71., PMID: 10869340  
  Moy FJ, Chanda PK, Cockett MI, Edris W, Jones PG, Mason K, Semus S, Powers R. "NMR structure of free RGS4 reveals an induced conformational change upon binding Galpha." Biochemistry. 2000; 39(24): 7063-73., PMID: 10852703  
 Region 1, Region 2Tesmer JJ, Berman DM, Gilman AG, Sprang SR. "Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis." Cell. 1997; 89(2): 251-61., PMID: 9108480  
DP00064 Abad-Zapatero C, Abdel-Meguid SS, Johnson JE, Leslie AG, Rayment I, Rossmann MG, Suck D, Tsukihara T. "Structure of southern bean mosaid virus at 2.8 A resolution." Nature. 1980; 286(5768): 33-9., PMID: 19711553  
  Hermodson MA, Abad-Zapatero C, Abdel-Meguid S, Pundak S, Rossmann MG, Tremaine J. "Amino acid sequence of southern bean mosaic virus coat protein and its relation to the three-dimensional structure of the virus." Virology. 1982; 119: 133-149. 
 Region 1, Region 2, Region 3, Region 8, Region 9Hermodson MA, Abad-Zapatero C, Abdel-Meguid S, Pundak S, Rossmann MG, Tremaine J. "Amino acid sequence of southern bean mosaic virus coat protein and its relation to the three-dimensional structure of the virus." Virology. 1982; 119: 133-149. 
 Region 7Silva AM, Rossmann MG. "Refined structure of southern bean mosaic virus at 2.9 A resolution." J Mol Biol. 1987; 197(1): 69-87., PMID: 3681993  
 Region 4, Region 5, Region 6Rossmann MG, Abad-Zapatero C, Erickson JW, Savithri HS. "RNA-protein interactions in some small plant viruses." J Biomol Struct Dyn. 1983; 1(2): 565-79., PMID: 6401119  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9Rossmann MG, Abad-Zapatero C, Hermodson MA, Erickson JW. "Subunit interactions in southern bean mosaic virus." J Mol Biol. 1983; 166(1): 37-73., PMID: 6854633  
DP00065 Josefsson E, O'Connell D, Foster TJ, Durussel I, Cox JA. "The binding of calcium to the B-repeat segment of SdrD, a cell surface protein of Staphylococcus aureus." J Biol Chem. 1998; 273(47): 31145-52., PMID: 9813018  
 Region 1Josefsson E, O'Connell D, Foster TJ, Durussel I, Cox JA. "The binding of calcium to the B-repeat segment of SdrD, a cell surface protein of Staphylococcus aureus." J Biol Chem. 1998; 273(47): 31145-52., PMID: 9813018  
DP00066 Choi HK, Lee S, Zhang YP, McKinney BR, Wengler G, Rossmann MG, Kuhn RJ. "Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis." J Mol Biol. 1996; 262(2): 151-167., PMID: 8831786  
DP00066_C001 Choi HK, Tong L, Minor W, Dumas P, Boege U, Rossmann MG, Wengler G. "Structure of Sindbis virus core protein reveals a chymotrypsin-like serine proteinase and the organization of the virion." Nature. 1991; 354(6348): 37-43., PMID: 1944569  
 Region 1Choi HK, Tong L, Minor W, Dumas P, Boege U, Rossmann MG, Wengler G. "Structure of Sindbis virus core protein reveals a chymotrypsin-like serine proteinase and the organization of the virion." Nature. 1991; 354(6348): 37-43., PMID: 1944569  
DP00067 Kim KK, Kim R, Kim SH. "Crystal structure of a small heat-shock protein." Nature. 1998; 394(6693): 595-9., PMID: 9707123  
 Region 1Kim KK, Kim R, Kim SH. "Crystal structure of a small heat-shock protein." Nature. 1998; 394(6693): 595-9., PMID: 9707123  
DP00068 Brunger AT. "Structural insights into the molecular mechanism of Ca(2+)-dependent exocytosis." Curr Opin Neurobiol. 2000; 10(3): 293-302., PMID: 10851178  
 Region 1Fasshauer D, Eliason WK, Brünger AT, Jahn R. "Identification of a minimal core of the synaptic SNARE complex sufficient for reversible assembly and disassembly." Biochemistry. 1998; 37(29): 10354-62., PMID: 9671503  
DP00069Region 3Cánaves JM, Montal M. "Assembly of a ternary complex by the predicted minimal coiled-coil-forming domains of syntaxin, SNAP-25, and synaptobrevin. A circular dichroism study." J Biol Chem. 1998; 273(51): 34214-21., PMID: 9852083  
 Region 1Fasshauer D, Otto H, Eliason WK, Jahn R, Brunger AT. "Structural changes are associated with soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor complex formation." J Biol Chem. 1997; 272(44): 28036-41., PMID: 9346956 brunger@stanford.edu
 Region 2Hazzard J, Sudhof TC, Rizo J. "NMR analysis of the structure of synaptobrevin and of its interaction with syntaxin." J Biomol NMR. 1999; 14(3): 203-207., PMID: 10481273  
DP00070 Frimpong AK, Abzalimov RR, Uversky VN, Kaltashov IA. "Characterization of intrinsically disordered proteins with electrospray ionization mass spectrometry: Conformational heterogeneity of alpha-synuclein." Proteins. 2009., PMID: 19847913  
  P. Tompa. "Structural disorder in amyloid fibrils: its implication in dynamic interactions of proteins." FEBS J. 2009; 27 Aug., PMID: 19712107  
  Zhou W, Long C, Reaney SH, Di Monte DA, Fink AL, Uversky VN. "Methionine oxidation stabilizes non-toxic oligomers of alpha-synuclein through strengthening the auto-inhibitory intra-molecular long-range interactions." Biochim Biophys Acta. 2009., PMID: 20026206  
  Allison JR, Varnai P, Dobson CM, Vendruscolo M. "Determination of the free energy landscape of alpha-synuclein using spin label nuclear magnetic resonance measurements." J Am Chem Soc. 2009; 131(51): 18314-26., PMID: 20028147  
  Uversky VN, Li J, Fink AL. "Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease." FEBS Lett. 2001; 500(3): 105-8., PMID: 11445065  
  Uversky VN. "A protein-chameleon: conformational plasticity of alpha-synuclein, a disordered protein involved in neurodegenerative disorders." J Biomol Struct Dyn. 2003; 21(2): 211-34., PMID: 12956606 vuversky@iupui.edu
  Lee JC, Lai BT, Kozak JJ, Gray HB, Winkler JR. "Alpha-synuclein tertiary contact dynamics." J Phys Chem B. 2007; 111(8): 2107-12., PMID: 17279794  
 Region 1Weinreb PH, Zhen W, Poon AW, Conway KA, Lansbury PT Jr. "NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded." Biochemistry. 1996; 35(43): 13709-13715., PMID: 8901511  
 Region 1Nielsen, M. S. Vorum, H. Lindersson, E. Jensen, P. H. "Ca2+ binding to alpha-synuclein regulates ligand binding and oligomerization." J Biol Chem. 2001; 276(25): 22680-22684., PMID: 11312271  
 Region 1Eliezer D, Kutluay E, Bussell R Jr, Browne G. "Conformational properties of alpha-synuclein in its free and lipid-associated states." J Mol Biol. 2001; 307(4): 1061-73., PMID: 11286556 dae2005@mail.med.cor
nell.edu
 Region 1Bussell R Jr, Eliezer D. "Residual structure and dynamics in Parkinson's disease-associated mutants of alpha-synuclein." J Biol Chem. 2001; 276(49): 45996-6003., PMID: 11590151  
DP00071Region 3, Region 4, Region 5Esposito G, Fogolari F, Damante G, Formisano S, Tell G, Leonardi A, Di Lauro R, Viglino P. "Analysis of the solution structure of the homeodomain of rat thyroid transcription factor 1 by 1H-NMR spectroscopy and restrained molecular mechanics." Eur. J. Biochem.. 1996; 241(1): 101-13., PMID: 8898894  
 Region 1, Region 2Tell G, Perrone L, Fabbro D, Pellizzari L, Pucillo C, De Felice M, Acquaviva R, Formisano S, Damante G. "Structural and functional properties of the N transcriptional activation domain of thyroid transcription factor-1: similarities with the acidic activation domains." Biochem J. 1998; 329 ( Pt 2): 395-403., PMID: 9425125  
 Region 3, Region 4, Region 5Viglino P, Fogolari F, Formisano S, Bortolotti N, Damante G, Di Lauro R, Esposito G. "Structural study of rat thyroid transcription factor 1 homeodomain (TTF-1 HD) by nuclear magnetic resonance." FEBS Lett.. 1993; 336(3): 397-402., PMID: 8282100  
DP00072 Kellermayer MS, Smith SB, Granzier HL, Bustamante C. "Folding-unfolding transitions in single titin molecules characterized with laser tweezers." Science. 1997; 276(5315): 1112-6., PMID: 9148805  
  Helmes M, Trombitas K, Centner T, Kellermayer M, Labeit S, Linke WA, Granzier H. "Mechanically driven contour-length adjustment in rat cardiac titin's unique N2B sequence: titin is an adjustable spring." Circ Res. 1999; 84(11): 1339-52., PMID: 10364572  
  Ma K, Kan L, Wang K. "Polyproline II helix is a key structural motif of the elastic PEVK segment of titin." Biochemistry. 2001; 40(12): 3427-38., PMID: 11297408  
 Region 1Labeit S, Kolmerer B. "Titins: giant proteins in charge of muscle ultrastructure and elasticity." Science. 1995; 270(5234): 293-6., PMID: 7569978 labeit@embl-heidelbe
rg.de
 Region 1Trombitas K, Greaser M, Labeit S, Jin JP, Kellermayer M, Helmes M, Granzier H. "Titin extensibility in situ: entropic elasticity of permanently folded and permanently unfolded molecular segments." J Cell Biol. 1998; 140(4): 853-9., PMID: 9472037  
DP00073Region 1, Region 4Phan J, Steadman DJ, Koli S, Ding WC, Minor W, Dunlap RB, Berger SH, Lebioda L. "Structure of human thymidylate synthase suggests advantages of chemotherapy with noncompetitive inhibitors." J Biol Chem. 2001; 276(17): 14170-7., PMID: 11278511  
 Region 1, Region 2, Region 3Schiffer CA, Clifton IJ, Davisson VJ, Santi DV, Stroud RM. "Crystal structure of human thymidylate synthase: a structural mechanism for guiding substrates into the active site." Biochemistry. 1995; 34(50): 16279-87., PMID: 8845352  
DP00074 Krust A, Green S, Argos P, Kumar V, Walter P, Bornert JM, Chambon P. "The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors." Embo J. 1986; 5(5): 891-7., PMID: 3755102  
 Region 1Warnmark A, Wikstrom A, Wright AP, Gustafsson JA, Hard T. "The N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding properties." J Biol Chem. 2001; 276(49): 45939-44., PMID: 11595744  
 Region 2, Region 3Schwabe JW, Chapman L, Finch JT, Rhodes D, Neuhaus D. "DNA recognition by the oestrogen receptor: from solution to the crystal." Structure. 1993; 1(3): 187-204., PMID: 16100953  
DP00075Region 1, Region 2, Region 3, Region 4Bharti AK, Olson MO, Kufe DW, Rubin EH. "Identification of a nucleolin binding site in human topoisomerase I." J Biol Chem. 1996; 271(4): 1993-7., PMID: 8567649  
 Region 3, Region 4Lisby M, Olesen JR, Skouboe C, Krogh BO, Straub T, Boege F, Velmurugan S, Martensen PM, Andersen AH, Jayaram M, Westergaard O, Knudsen BR. "Residues within the N-terminal domain of human topoisomerase I play a direct role in relaxation." J Biol Chem. 2001; 276(23): 20220-20227., PMID: 11283003  
 Region 1, Region 2Shaiu WL, Hu T, Hsieh TS. "The hydrophilic, protease-sensitive terminal domains of eucaryotic DNA topoisomerases have essential intracellular functions." Pac Symp Biocomput. 1999: 578-589., PMID: 10380229  
 Region 3, Region 4Frohlich RF, Andersen FF, Westergaard O, Andersen AH, Knudsen BR. "Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding." J Mol Biol. 2004; 336(1): 93-103., PMID: 14741206  
 Region 7, Region 13, Region 14, Region 15, Region 16, Region 17, Region 18, Region 19, Region 20, Region 21, Region 22, Region 23, Region 24Redinbo MR, Stewart L, Champoux JJ, Hol WG. "Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures." J Mol Biol. 1999; 292(3): 685-696., PMID: 10497031  
 Region 2Labourier E, Rossi F, Gallouzi IE, Allemand E, Divita G, Tazi J. "Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factor." Nucleic Acids Res. 1998; 26(12): 2955-2962., PMID: 9611241  
 Region 1, Region 2Stewart L, Ireton GC, Parker LH, Madden KR, Champoux JJ. "Biochemical and biophysical analyses of recombinant forms of human topoisomerase I." J Biol Chem. 1996; 271(13): 7593-7601., PMID: 8631793  
 Region 3, Region 6, Region 9, Region 10, Region 12Redinbo MR, Stewart L, Kuhn P, Champoux JJ, Hol WG. "Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA." Science. 1998; 279(5356): 1504-1153., PMID: 9488644  
 Region 3, Region 4Christensen MO, Barthelmes HU, Boege F, Mielke C. "Residues 190-210 of human topoisomerase I are required for enzyme activity in vivo but not in vitro." Nucleic Acids Res. 2003; 31(24): 7255-63., PMID: 14654701  
 Region 4, Region 5, Region 7, Region 8, Region 11Stewart L, Redinbo MR, Qiu X, Hol WG, Champoux JJ. "A model for the mechanism of human topoisomerase I." Science. 1998; 279(5356): 1534-1541., PMID: 9488652  
 Region 2Stewart L, Ireton GC, Champoux JJ. "The domain organization of human topoisomerase I." J Biol Chem. 1996; 271(13): 7602-7608., PMID: 8631794  
DP00076Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10Berger JM, Gamblin SJ, Harrison SC, Wang JC. "Structure and mechanism of DNA topoisomerase II." Nature. 1996; 379(6562): 225-32., PMID: 8538787  
 Region 11Shaiu WL, Hu T, Hsieh TS. "The hydrophilic, protease-sensitive terminal domains of eucaryotic DNA topoisomerases have essential intracellular functions." Pac Symp Biocomput. 1999: 578-589., PMID: 10380229  
 Region 3, Region 11Dunker AK, Brown CJ, Lawson JD, Iakoucheva LM, Obradović Z. "Intrinsic disorder and protein function." Biochemistry. 2002; 41(21): 6573-82., PMID: 12022860  
DP00077 Hartshorne TA, Blumberg H, Young ET. "Sequence homology of the yeast regulatory protein ADR1 with Xenopus transcription factor TFIIIA." Nature. 1986; 320(6059): 283-7., PMID: 3515197  
 Region 1, Region 2Hyre DE, Klevit RE. "A disorder-to-order transition coupled to DNA binding in the essential zinc-finger DNA-binding domain of yeast ADR1." Journal of Molecular Biology. 1998; 279(4): 929-943., PMID: 9642072  
 Region 1, Region 2Hartshorne TA, Blumberg H, Young ET. "Sequence homology of the yeast regulatory protein ADR1 with Xenopus transcription factor TFIIIA." Nature. 1986; 320(6059): 283-7., PMID: 3515197  
DP00078Region 1Campbell KM, Terrell AR, Laybourn PJ, Lumb KJ. "Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos." Biochemistry. 2000; 39(10): 2708-13., PMID: 10704222  
 Region 1Flaugh SL, Lumb KJ. "Effects of macromolecular crowding on the intrinsically disordered proteins c-Fos and p27(Kip1)." Biomacromolecules. 2001; 2(2): 538-540., PMID: 11749217  
DP00079 Warnmark A, Wikstrom A, Wright AP, Gustafsson JA, Hard T. "The N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding properties." J Biol Chem. 2001; 276(49): 45939-44., PMID: 11595744  
 Region 1Warnmark A, Wikstrom A, Wright AP, Gustafsson JA, Hard T. "The N-terminal regions of estrogen receptor alpha and beta are unstructured in vitro and show different TBP binding properties." J Biol Chem. 2001; 276(49): 45939-44., PMID: 11595744  
DP00080 Gonzales G, Yamamoto K, Fischer W, Karr D, Menzel P, Biggs W, Vale W, Montminy M. "A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence." Nature. 1989; 337: 749-752. 
  Short ML, Manohar CF, Furtado MR, Ghadge GD, Wolinsky SM, Thimmapaya B, Jungmann RA. "Nucleotide and derived amino-acid sequences of the CRE-binding proteins from rat C6 glioma and HeLa cells." Nucleic Acids Res. 1991; 19(15): 4290., PMID: 1831258  
 Region 1, Region 2, Region 3Radhakrishnan I, Perez-Alvarado GC, Parker D, Dyson HJ, Montminy MR, Wright PE. "Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions." Cell. 1997; 91(6): 741-752., PMID: 9413984  
 Region 2Radhakrishnan I, Perez-Alvarado GC, Dyson HJ, Wright PE. "Conformational preferences in the Ser133-phosphorylated and non-phosphorylated forms of the kinase inducible transactivation domain of CREB." FEBS Lett. 1998; 430(3): 317-322., PMID: 9688563  
DP00081 Liu D, Ishima R, Tong KI, Bagby S, Kokubo T, Muhandiram DR, Kay LE, Nakatani Y, Ikura M. "Solution structure of a TBP-TAF(II)230 complex: protein mimicry of the minor groove surface of the TATA box unwound by TBP." Cell. 1998; 94(5): 573-583., PMID: 9741622  
 Region 1Liu D, Ishima R, Tong KI, Bagby S, Kokubo T, Muhandiram DR, Kay LE, Nakatani Y, Ikura M. "Solution structure of a TBP-TAF(II)230 complex: protein mimicry of the minor groove surface of the TATA box unwound by TBP." Cell. 1998; 94(5): 573-583., PMID: 9741622  
DP00082Region 1Hershey PE, McWhirter SM, Gross JD, Wagner G, Alber T, Sachs AB. "The Cap-binding protein eIF4E promotes folding of a functional domain of yeast translation initiation factor eIF4G1." J Biol Chem. 1999; 274(30): 21297-304., PMID: 10409688  
DP00083Region 1Weiss MA, Ellenberger T, Wobbe CR, Lee JP, Harrison SC, Struhl K. "Folding transition in the DNA-binding domain of GCN4 on specific binding to DNA." Nature. 1990; 347(6293): 575-8., PMID: 2145515  
DP00084 Ferre-D'Amare AR, Pognonec P, Roeder RG, Burley SK. "Structure and function of the b/HLH/Z domain of USF." Embo J. 1994; 13(1): 180-9., PMID: 8306960  
  Sauve S, Tremblay L, Lavigne P. "The NMR solution structure of a mutant of the Max b/HLH/LZ free of DNA: insights into the specific and reversible DNA binding mechanism of dimeric transcription factors." J Mol Biol. 2004; 342(3): 813-32., PMID: 15342239  
  Pursglove SE, Fladvad M, Bellanda M, Moshref A, Henriksson M, Carey J, Sunnerhagen M. "Biophysical properties of regions flanking the bHLH-Zip motif in the p22 Max protein." Biochem Biophys Res Commun. 2004; 323(3): 750-9., PMID: 15381064  
 Region 1Horiuchi M, Kurihara Y, Katahira M, Maeda T, Saito T, Uesugi S. "Dimerization and DNA binding facilitate alpha-helix formation of Max in solution." J Biochem (Tokyo). 1997; 122(4): 711-6., PMID: 9399572  
DP00084_A002Region 1, Region 2Naud JF, McDuff FO, Sauve S, Montagne M, Webb BA, Smith SP, Chabot B, Lavigne P. "Structural and Thermodynamical Characterization of the Complete p21 Gene Product of Max." Biochemistry. 2005; 44(38): 12746-12758., PMID: 16171389 Pierre.Lavigne@Usher
brooke.ca
DP00085 Ruben SM, Dillon PJ, Schreck R, Henkel T, Chen CH, Maher M, Baeuerle PA, Rosen CA. "Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B." Science. 1991; 251(5000): 1490-1493., PMID: 2006423  
 Region 1, Region 2Schmitz ML, Baeuerle PA. "The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B." Embo J. 1991; 10(12): 3805-3817., PMID: 1935902  
 Region 1, Region 2, Region 3Schmitz ML, dos Santos Silva MA, Altmann H, Czisch M, Holak TA, Baeuerle PA. "Structural and functional analysis of the NF-kappa B p65 C terminus. An acidic and modular transactivation domain with the potential to adopt an alpha-helical conformation." J Biol Chem. 1994; 269(41): 25613-25620., PMID: 7929265  
DP00086 Tidow H, Melero R, Mylonas E, Freund SM, Grossmann JG, Carazo JM, Svergun DI, Valle M, Fersht AR. "Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex." Proc Natl Acad Sci U S A. 2007; 104(30): 12324-9., PMID: 17620598  
  Soussi T, Caron de Fromentel C, May P. "Structural aspects of the p53 protein in relation to gene evolution." Oncogene. 1990; 5(7): 945-52., PMID: 2142762  
  Huang F, Rajagopalan S, Settanni G, Marsh RJ, Armoogum DA, Nicolaou N, Bain AJ, Lerner E, Haas E, Ying L, Fersht AR. "Multiple conformations of full-length p53 detected with single-molecule fluorescence resonance energy transfer." Proc Natl Acad Sci U S A. 2009., PMID: 19933326  
  Sharma AK, Ali A, Gogna R, Singh AK, Pati U. "p53 Amino-terminus region (1-125) stabilizes and restores heat denatured p53 wild phenotype." PLoS One. 2009; 4(10): e7159., PMID: 19847292  
 Region 1Chang J, Kim DH, Lee SW, Choi KY, Sung YC. "Transactivation ability of p53 transcriptional activation domain is directly related to the binding affinity to TATA-binding protein." J Biol Chem. 1995; 270(42): 25014-9., PMID: 7559631  
 Region 8, Region 9Kuszewski J, Gronenborn AM, Clore GM. "Improving the packing and accuracy of NMR structures with a pseudopotential for the radius of gyration." J Am Chem Soc. 1999; 121(10): 2337-8. 
 Region 4, Region 5, Region 6Derbyshire DJ, Basu BP, Date T, Iwabuchi K, Doherty AJ. "Purification, crystallization and preliminary X-ray analysis of the BRCT domains of human 53BP1 bound to the p53 tumour suppressor." Acta Crystallogr D Biol Crystallogr. 2002; 58(Pt 10 Pt 2): 1826-9., PMID: 12351827  
 Region 2, Region 3Kussie PH, Gorina S, Marechal V, Elenbaas B, Moreau J, Levine AJ, Pavletich NP. "Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain." Science. 1996; 274(5289): 948-53., PMID: 8875929  
 Region 4, Region 5, Region 6Derbyshire DJ, Basu BP, Serpell LC, Joo WS, Date T, Iwabuchi K, Doherty AJ. "Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor." EMBO J. 2002; 21(14): 3863-72., PMID: 12110597  
 Region 7Joerger AC, Allen MD, Fersht AR. "Crystal structure of a superstable mutant of human p53 core domain. Insights into the mechanism of rescuing oncogenic mutations." J Biol Chem. 2004; 279(2): 1291-6., PMID: 14534297  
DP00087 Uesugi M, Nyanguile O, Lu H, Levine AJ, Verdine GL. "Induced alpha helix in the VP16 activation domain upon binding to a human TAF." Science. 1997; 277(5330): 1310-3., PMID: 9271577  
  Shen F, Triezenberg SJ, Hensley P, Porter D, Knutson JR. "Critical amino acids in the transcriptional activation domain of the herpesvirus protein VP16 are solvent-exposed in highly mobile protein segments. An intrinsic fluorescence study." J Biol Chem. 1996; 271(9): 4819-26., PMID: 8617751  
  Hayes S, O'Hare P. "Mapping of a major surface-exposed site in herpes simplex virus protein Vmw65 to a region of direct interaction in a transcription complex assembly." J Virol. 1993; 67(2): 852-62., PMID: 8380468  
  O'Hare P, Williams G. "Structural studies of the acidic transactivation domain of the Vmw65 protein of herpes simplex virus using 1H NMR." Biochemistry. 1992; 31(16): 4150-6., PMID: 1314658  
  Donaldson L, Capone JP. "Purification and characterization of the carboxyl-terminal transactivation domain of Vmw65 from herpes simplex virus type 1." J Biol Chem. 1992; 267(3): 1411-4., PMID: 1309782  
 Region 1, Region 2Liu Y, Gong W, Huang CC, Herr W, Cheng X. "Crystal structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16." Genes Dev. 1999; 13(13): 1692-703., PMID: 10398682  
DP00088 Wilmanns M, Lappalainen P, Kelly M, Sauer-Eriksson E, Saraste M. "Crystal structure of the membrane-exposed domain from a respiratory quinol oxidase complex with an engineered dinuclear copper center." Proc Natl Acad Sci U S A. 1995; 92(26): 11955-9., PMID: 8618822  
 Region 1, Region 2, Region 3, Region 4, Region 5Abramson J, Riistama S, Larsson G, Jasaitis A, Svensson-Ek M, Laakkonen L, Puustinen A, Iwata S, Wikstrom M. "The structure of the ubiquinol oxidase from Escherichia coli and its ubiquinone binding site." Nat Struct Biol. 2000; 7(10): 910-7., PMID: 11017202  
 Region 1, Region 2, Region 3, Region 4, Region 5Chepuri V, Lemieux L, Au DC, Gennis RB. "The sequence of the cyo operon indicates substantial structural similarities between the cytochrome o ubiquinol oxidase of Escherichia coli and the aa3-type family of cytochrome c oxidases." J Biol Chem. 1990; 265(19): 11185-92., PMID: 2162835  
DP00089 Chepuri V, Lemieux L, Au DC, Gennis RB. "The sequence of the cyo operon indicates substantial structural similarities between the cytochrome o ubiquinol oxidase of Escherichia coli and the aa3-type family of cytochrome c oxidases." J Biol Chem. 1990; 265(19): 11185-92., PMID: 2162835  
 Region 3, Region 4van der Oost J, Musacchio A, Pauptit RA, Ceska TA, Wierenga RK, Saraste M. "Crystallization and preliminary X-ray analysis of the periplasmic fragment of CyoA-a subunit of the Escherichia coli cytochrome o complex." J Mol Biol. 1993; 229(3): 794-6., PMID: 8433374  
 Region 1, Region 2Abramson J, Riistama S, Larsson G, Jasaitis A, Svensson-Ek M, Laakkonen L, Puustinen A, Iwata S, Wikstrom M. "The structure of the ubiquinol oxidase from Escherichia coli and its ubiquinone binding site." Nat Struct Biol. 2000; 7(10): 910-7., PMID: 11017202  
 Region 3, Region 4Wilmanns M, Lappalainen P, Kelly M, Sauer-Eriksson E, Saraste M. "Crystal structure of the membrane-exposed domain from a respiratory quinol oxidase complex with an engineered dinuclear copper center." Proc Natl Acad Sci U S A. 1995; 92(26): 11955-9., PMID: 8618822  
 Region 3, Region 4van der Oost J, Lappalainen P, Musacchio A, Warne A, Lemieux L, Rumbley J, Gennis RB, Aasa R, Pascher T, Malmstrom BG, et al. "Restoration of a lost metal-binding site: construction of two different copper sites into a subunit of the E. coli cytochrome o quinol oxidase complex." Embo J. 1992; 11(9): 3209-17., PMID: 1324168  
DP00090Region 1Wissmann R, Baukrowitz T, Kalbacher H, Kalbitzer HR, Ruppersberg JP, Pongs O, Antz C, Fakler B. "NMR structure and functional characteristics of the hydrophilic N terminus of the potassium channel beta-subunit Kvbeta1.1." J Biol Chem. 1999; 274(50): 35521-5., PMID: 10585425  
DP00091Region 1, Region 2Iakoucheva LM, Kimzey AL, Masselon CD, Bruce JE, Garner EC, Brown CJ, Dunker AK, Smith RD, Ackerman EJ. "Identification of intrinsic order and disorder in the DNA repair protein XPA." Protein Sci. 2001; 10(3): 560-71., PMID: 11344324 eric.ackerman@pnl.go
v
DP00092 Muramatsu T, Kincaid RL. "Molecular cloning of a full-length cDNA encoding the catalytic subunit of human calmodulin-dependent protein phosphatase (calcineurin A alpha)." Biochim Biophys Acta. 1993; 1178(1): 117-20., PMID: 8392375  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Kissinger CR, Parge HE, Knighton DR, Lewis CT, Pelletier LA, Tempczyk A, Kalish VJ, Tucker KD, Showalter RE, Moomaw EW, et al. "Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex." Nature. 1995; 378(6557): 641-4., PMID: 8524402  
DP00094 Goodwill KE, Sabatier C, Marks C, Raag R, Fitzpatrick PF, Stevens RC. "Crystal structure of tyrosine hydroxylase at 2.3 A and its implications for inherited neurodegenerative diseases." Nat Struct Biol. 1997; 4(7): 578-85., PMID: 9228951  
 Region 1Daubner SC, Lohse DL, Fitzpatrick PF. "Expression and characterization of catalytic and regulatory domains of rat tyrosine hydroxylase." Protein Sci. 1993; 2(9): 1452-60., PMID: 8104613  
DP00095Region 1Brick P, Bhat TN, Blow DM. "Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate." J Mol Biol. 1989; 208(1): 83-98., PMID: 2504923  
 Region 1Guijarro JI, Pintar A, Prochnicka-Chalufour A, Guez V, Gilquin B, Bedouelle H, Delepierre M. "Structure and dynamics of the anticodon arm binding domain of Bacillus stearothermophilus Tyrosyl-tRNA synthetase." Structure (Camb). 2002; 10(3): 311-7., PMID: 12005430  
DP00096Region 1McManus E, Luisi BF, Perham RN. "Structure of a putative lipoate protein ligase from Thermoplasma acidophilum and the mechanism of target selection for post-translational modification." J Mol Biol. 2006; 356(3): 625-37., PMID: 16384580  
DP00097Region 1, Region 2Vila R, Ponte I, Collado M, Arrondo JL, Jimenez MA, Rico M, Suau P. "DNA-induced alpha-helical structure in the NH2-terminal domain of histone H1." J Biol Chem. 2001; 276(49): 46429-35., PMID: 11584004 pere.suau@uab.es
 Region 4Vila R, Ponte I, Collado M, Arrondo JL, Suau P. "Induction of secondary structure in a COOH-terminal peptide of histone H1 by interaction with the DNA: an infrared spectroscopy study." J Biol Chem. 2001; 276(33): 30898-903., PMID: 11413144  
 Region 3Roque A, Iloro I, Ponte I, Arrondo JL, Suau P. "DNA-induced secondary structure of the carboxyl-terminal domain of histone H1." J Biol Chem. 2005; 280(37): 32141-7., PMID: 16006555 pere.suau@uab.es
 Region 4Vila R, Ponte I, Jimenez MA, Rico M, Suau P. "A helix-turn motif in the C-terminal domain of histone H1." Protein Sci. 2000; 9(4): 627-36., PMID: 10794405  
DP00098Region 1Symersky J, Patti JM, Carson M, House-Pompeo K, Teale M, Moore D, Jin L, Schneider A, DeLucas LJ, Hook M, Narayana SV. "Structure of the collagen-binding domain from a Staphylococcus aureus adhesin." Nat Struct Biol. 1997; 4(10): 833-8., PMID: 9334749  
 Region 1Patti JM, Boles JO, Hook M. "Identification and biochemical characterization of the ligand binding domain of the collagen adhesin from Staphylococcus aureus." Biochemistry. 1993; 32(42): 11428-35., PMID: 8218209  
DP00099 Fritsche E, Humm A, Huber R. "Substrate binding and catalysis by L-arginine:glycine amidinotransferase--a mutagenesis and crystallographic study." Eur J Biochem. 1997; 247(2): 483-90., PMID: 9266688  
  Humm A, Fritsche E, Mann K, Gohl M, Huber R. "Recombinant expression and isolation of human L-arginine:glycine amidinotransferase and identification of its active-site cysteine residue." Biochem J. 1997; 322 ( Pt 3): 771-6., PMID: 9148748  
  Humm A, Huber R, Mann K. "The amino acid sequences of human and pig L-arginine:glycine amidinotransferase." FEBS Lett. 1994; 339(1-2): 101-7., PMID: 8313955  
 Region 1Humm A, Fritsche E, Steinbacher S, Huber R. "Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis." EMBO J. 1997; 16(12): 3373-85., PMID: 9218780  
 Region 1Humm A, Fritsche E, Steinbacher S. "Structure and reaction mechanism of L-arginine:glycine amidinotransferase." Biol Chem. 1997; 378(3-4): 193-7., PMID: 9165070  
DP00100Region 1Bochtler M, Hartmann C, Song HK, Bourenkov GP, Bartunik HD, Huber R. "The structures of HsIU and the ATP-dependent protease HsIU-HsIV." Nature. 2000; 403(6771): 800-5., PMID: 10693812  
DP00101_C006Region 1, Region 2, Region 3Fossen T, Wray V, Bruns K, Rachmat J, Henklein P, Tessmer U, Maczurek A, Klinger P, Schubert U. "Solution structure of the human immunodeficiency virus type 1 p6 protein." J Biol Chem. 2005., PMID: 16234236  
DP00102 Rovner, A. S. Freyzon, Y. Trybus, K. M. "An insert in the motor domain determines the functional properties of expressed smooth muscle myosin isoforms." Journal of Muscle Research and Cell Motility. 1997; 18(1): 103-110., PMID: 9147986  
  Yanagisawa M, Hamada Y, Katsuragawa Y, Imamura M, Mikawa T, Masaki T. "Complete primary structure of vertebrate smooth muscle myosin heavy chain deduced from its complementary DNA sequence. Implications on topography and function of myosin." J Mol Biol. 1987; 198(2): 143-57., PMID: 2892941  
 Region 3Rovner, A. S. Freyzon, Y. Trybus, K. M. "An insert in the motor domain determines the functional properties of expressed smooth muscle myosin isoforms." Journal of Muscle Research and Cell Motility. 1997; 18(1): 103-110., PMID: 9147986  
 Region 1, Region 2, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10Dominguez R, Freyzon Y, Trybus KM, Cohen C. "Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state." Cell. 1998; 94(5): 559-71., PMID: 9741621 dominguez@bbri.org
DP00103Region 1Harrison CJ, Hayer-Hartl M, Di Liberto M, Hartl F, Kuriyan J. "Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK." Science. 1997; 276(5311): 431-5., PMID: 9103205  
DP00104 Burley SK. "Picking up the TAB." Nature. 1996; 381(6578): 112-3., PMID: 8610004  
 Region 1Tan S, Hunziker Y, Sargent DF, Richmond TJ. "Crystal structure of a yeast TFIIA/TBP/DNA complex." Nature. 1996; 381(6578): 127-51., PMID: 8610010  
DP00105Region 1Shibata N, Masuda J, Tobimatsu T, Toraya T, Suto K, Morimoto Y, Yasuoka N. "A new mode of B12 binding and the direct participation of a potassium ion in enzyme catalysis: X-ray structure of diol dehydratase." Structure Fold Des. 1999; 7(8): 997-1008., PMID: 10467140  
DP00106Region 1Shibata N, Masuda J, Tobimatsu T, Toraya T, Suto K, Morimoto Y, Yasuoka N. "A new mode of B12 binding and the direct participation of a potassium ion in enzyme catalysis: X-ray structure of diol dehydratase." Structure Fold Des. 1999; 7(8): 997-1008., PMID: 10467140  
DP00107Region 1Logan DT, Su XD, Aberg A, Regnstrom K, Hajdu J, Eklund H, Nordlund P. "Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site." Structure. 1996; 4(9): 1053-64., PMID: 8805591  
DP00108Region 1Nicolet Y, Piras C, Legrand P, Hatchikian CE, Fontecilla-Camps JC. "Desulfovibrio desulfuricans iron hydrogenase: the structure shows unusual coordination to an active site Fe binuclear center." Structure Fold Des. 1999; 7(1): 13-23., PMID: 10368269  
DP00110Region 1Iverson TM, Alber BE, Kisker C, Ferry JG, Rees DC. "A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila." Biochemistry. 2000; 39(31): 9222-31., PMID: 10924115  
DP00111 Tymms MJ, Kola I. "Regulation of gene expression by transcription factors Ets-1 and Ets-2." Mol Reprod Dev. 1994; 39(2): 208-14., PMID: 7826624  
 Region 1Slupsky CM, Gentile LN, Donaldson LW, Mackereth CD, Seidel JJ, Graves BJ, McIntosh LP. "Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site." Proc Natl Acad Sci U S A. 1998; 95(21): 12129-34., PMID: 9770451  
 Region 2Pufall MA, Lee GM, Nelson ML, Kang HS, Velyvis A, Kay LE, McIntosh LP, Graves BJ. "Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region." Science. 2005; 309(5731): 142-5., PMID: 15994560  
DP00112Region 1Lisse T, Bartels D, Kalbitzer HR, Jaenicke R. "The recombinant dehydrin-like desiccation stress protein from the resurrection plant Craterostigma plantagineum displays no defined three-dimensional structure in its native state." Biol Chem. 1996; 377(9): 555-61., PMID: 9067253  
 Region 1Piatkowski D Schneider K Salamini F Bartels D. "Characterization of five abscisic acid-responsive cDNA clones isolated from the desiccation-tolerant plant Craterostigma plantagineum and their relationship to other water-stress genes." Plant Physiol. 1990; 94: 1682-1688. 
DP00113 Gerst JE, Rodgers L, Riggs M, Wigler M. "SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/synaptobrevin gene family: genetic interactions with the RAS and CAP genes." Proc Natl Acad Sci U S A. 1992; 89(10): 4338-42., PMID: 1316605  
 Region 1Rice LM, Brennwald P, Brunger AT. "Formation of a yeast SNARE complex is accompanied by significant structural changes." FEBS Lett. 1997; 415(1): 49-55., PMID: 9326367 brunger@stanford.edu
DP00114Region 1Jimenez MA, Evangelio JA, Aranda C, Lopez-Brauet A, Andreu D, Rico M, Lagos R, Andreu JM, Monasterio O. "Helicity of alpha(404-451) and beta(394-445) tubulin C-terminal recombinant peptides." Protein Sci. 1999; 8(4): 788-799., PMID: 10211825  
DP00116Region 1Colombo G, Fanti P, Yao C, Malluche HH. "Isolation and complete amino acid sequence of osteocalcin from canine bone." J Bone Miner Res. 1993; 8(6): 733-43., PMID: 8101026  
 Region 1Isbell DT, Du S, Schroering AG, Colombo G, Shelling JG. "Metal ion binding to dog osteocalcin studied by 1H NMR spectroscopy." Biochemistry. 1993; 32(42): 11352-11362., PMID: 8218200  
DP00117Region 1, Region 2, Region 3, Region 4Beswick V, Baleux F, Huynh-Dinh T, Kepes F, Neumann JM, Sanson A. "NMR conformational study of the cytoplasmic domain of the canine Sec61 gamma protein from the protein translocation pore of the endoplasmic reticulum membrane." Biochemistry. 1996; 35(47): 14717-24., PMID: 8942632  
DP00118Region 1Grimes M, Iacangelo A, Eiden LE, Godfrey B, Herbert E. "Chromogranin A: the primary structure deduced from cDNA clones reveals the presence of pairs of basic amino acids." Ann N Y Acad Sci. 1987; 493: 351-378., PMID: 3473966  
 Region 1Yoo SH, Ferretti JA. "Nature of the pH-induced conformational changes and exposure of the C-terminal region of chromogranin A." FEBS Lett. 1993; 334(3): 373-377., PMID: 8243650  
DP00119 Maeda N, Kim HS, Azen EA, Smithies O. "Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system." J Biol Chem. 1985; 260(20): 11123-30., PMID: 2993301  
 Region 1Loomis RE, Bergey EJ, Levine MJ, Tabak LA. "Circular dichroism and fluorescence spectroscopic analyses of a proline-rich glycoprotein from human parotid saliva." Int J Pept Protein Res. 1985; 26(6): 621-9., PMID: 4093242  
 Region 1Loomis RE, Tseng Ching-Chung, Levine MJ. "Dynamics of a proline-rich glycoprotein from human parotid saliva: a 360-MHz proton nuclear magnetic resonance investigation." Int J Biol Macromol. 1986; 8: 149-52. 
DP00120 Lynch WP, Riseman VM, Bretscher A. "Smooth muscle caldesmon is an extended flexible monomeric protein in solution that can readily undergo reversible intra- and intermolecular sulfhydryl cross-linking. A mechanism for caldesmon's F-actin bundling activity." J Biol Chem. 1987; 262(15): 7429-37., PMID: 3584120  
  Haruna M, Hayashi K, Yano H, Takeuchi O, Sobue K. "Common structural and expressional properties of vertebrate caldesmon genes." Biochem Biophys Res Commun. 1993; 197(1): 145-53., PMID: 8250919  
 Region 1Hayashi K, Kanda K, Kimizuka F, Kato I, Sobue K. "Primary structure and functional expression of h-caldesmon complementary DNA." Biochem Biophys Res Commun. 1989; 164(1): 503-511., PMID: 2803315  
 Region 1Permyakov SE, Millett IS, Doniach S, Permyakov EA, Uversky VN. "Natively unfolded C-terminal domain of caldesmon remains substantially unstructured after the effective binding to calmodulin." Proteins. 2003; 53(4): 855-862., PMID: 14635127 vuversky@iupui.edu
 Region 1Czuryło EA. "Motifs of the caldesmon family." Acta Biochim Pol. 2000; 47(4): 1019-26., PMID: 11996092  
DP00121Region 2, Region 3, Region 4, Region 5, Region 6Ramirez-Alvarado M, Serrano L, Blanco FJ. "Conformational analysis of peptides corresponding to all the secondary structure elements of protein L B1 domain: secondary structure propensities are not conserved in proteins with the same fold." Protein Sci. 1997; 6(1): 162-174., PMID: 9007989  
 Region 1Wikstroem M, Sjoebring U, Kastern W, Bjoerck L. "Proton nuclear magnetic resonance sequential assignments and secondary structure of an immunoglobulin light chain-binding domain of protein L." 1993; 32: 3381. 
DP00122 Csizmok V, Bokor M, Banki P, Klement E, Medzihradszky KF, Friedrich P, Tompa K, Tompa P. "Primary contact sites in intrinsically unstructured proteins: the case of calpastatin and microtubule-associated protein 2." Biochemistry. 2005; 44(10): 3955-64., PMID: 15751971  
 Region 1Csizmok V, Bokor M, Banki P, Klement E, Medzihradszky KF, Friedrich P, Tompa K, Tompa P. "Primary contact sites in intrinsically unstructured proteins: the case of calpastatin and microtubule-associated protein 2." Biochemistry. 2005; 44(10): 3955-64., PMID: 15751971  
DP00123 Konig R, Zhou W. "Signal transduction in T helper cells: CD4 coreceptors exert complex regulatory effects on T cell activation and function." Curr Issues Mol Biol. 2004; 6(1): 1-15., PMID: 14632255  
 Region 1Wray V, Mertins D, Kiess M, Henklein P, Trowitzsch-Kienast W, Schubert U. "Solution structure of the cytoplasmic domain of the human CD4 glycoprotein by CD and 1H NMR spectroscopy: implications for biological functions." Biochemistry. 1998; 37(23): 8527-38., PMID: 9622505 victor.wray@helmholt
z-hzi.de
DP00124Region 1Yoo SH, Kang YK. "Identification of the secretory vesicle membrane binding region of chromogranin B." FEBS Lett. 1997; 406(3): 259-62., PMID: 9136897  
DP00125 Esch F, Bohlen P, Ling N, Brazeau P, Guillemin R. "Isolation and characterization of the bovine hypothalamic growth hormone releasing factor." Biochem Biophys Res Commun. 1983; 117(3): 772-9., PMID: 6421287  
 Region 1Sarver RW Jr, Friedman AR, Thamann TJ. "Spectroscopic studies on the conformational transitions of a bovine growth hormone releasing factor analog." Spectrochim Acta A Mol Biomol Spectrosc. 1997; 53A(11): 1889-900., PMID: 9375414  
DP00126 Mo ZY, Zhu YZ, Zhu HL, Fan JB, Chen J, Liang Y. "Low micromolar zinc accelerates the fibrillization of human tau via bridging of Cys-291 and Cys-322." J Biol Chem. 2009; 284(50): 34648-57., PMID: 19826005  
 Region 6Eliezer D, Barre P, Kobaslija M, Chan D, Li X, Heend L. "Residual structure in the repeat domain of tau: echoes of microtubule binding and paired helical filament formation." Biochemistry. 2005; 44(3): 1026-36., PMID: 15654759  
 Region 1, Region 3, Region 5Barghorn S, Davies P, Mandelkow E. "Tau paired helical filaments from Alzheimer's disease brain and assembled in vitro are based on beta-structure in the core domain." Biochemistry. 2004; 43(6): 1694-703., PMID: 14769047 mand@mpasmb.desy.de
 Region 1, Region 2, Region 3, Region 4, Region 5Schweers O, Schonbrunn-Hanebeck E, Marx A, Mandelkow E. "Structural studies of tau protein and Alzheimer paired helical filaments show no evidence for beta-structure." J Biol Chem. 1994; 269(39): 24290-24297., PMID: 7929085 mand@mpasmb.desy.de
 Region 1, Region 2, Region 4Santarella RA, Skiniotis G, Goldie KN, Tittmann P, Gross H, Mandelkow EM, Mandelkow E, Hoenger A. "Surface-decoration of microtubules by human tau." J Mol Biol. 2004; 339(3): 539-553., PMID: 15147841  
 Region 1, Region 2, Region 3, Region 4, Region 5Goedert M, Spillantini MG, Jakes R, Rutherford D, Crowther RA. "Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease." Neuron. 1989; 3(4): 519-526., PMID: 2484340  
DP00127Region 1House-Pompeo K, Xu Y, Joh D, Speziale P, Hook M. "Conformational changes in the fibronectin binding MSCRAMMs are induced by ligand binding." J Biol Chem. 1996; 271(3): 1379-84., PMID: 8576127  
DP00128Region 1Fiebig KM, Rice LM, Pollock E, Brunger AT. "Folding intermediates of SNARE complex assembly." Nat Struct Biol. 1999; 6(2): 117-23., PMID: 10048921 brunger@stanford.edu
 Region 2Rice LM, Brennwald P, Brunger AT. "Formation of a yeast SNARE complex is accompanied by significant structural changes." FEBS Lett. 1997; 415(1): 49-55., PMID: 9326367 brunger@stanford.edu
DP00129Region 3Huang DB, Huxford T, Chen YQ, Ghosh G. "The role of DNA in the mechanism of NFkappaB dimer formation: crystal structures of the dimerization domains of the p50 and p65 subunits." Structure. 1997; 5(11): 1427-36., PMID: 9384558  
 Region 1, Region 2Malek S, Huang DB, Huxford T, Ghosh S, Ghosh G. "X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex." J Biol Chem. 2003; 278(25): 23094-100., PMID: 12686541  
DP00130Region 1, Region 2Kartasova T, van de Putte P. "Isolation, characterization, and UV-stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes." Mol Cell Biol. 1988; 8(5): 2195-2203., PMID: 3133554  
 Region 1, Region 2Tarcsa E, Candi E, Kartasova T, Idler WW, Marekov LN, Steinert PM. "Structural and transglutaminase substrate properties of the small proline-rich 2 family of cornified cell envelope proteins." J Biol Chem. 1998; 273(36): 23297-23303., PMID: 9722562  
DP00131 Fischer RS, Fowler VM. "Tropomodulins: life at the slow end." Trends Cell Biol. 2003; 13(11): 593-601., PMID: 14573353  
 Region 1Kostyukova AS, Tiktopulo EI, Maeda Y. "Folding properties of functional domains of tropomodulin." Biophys J. 2001; 81(1): 345-51., PMID: 11423419 kostyuas@umdnj.edu
 Region 1Greenfield NJ, Kostyukova AS, Hitchcock-DeGregori SE. "Structure and tropomyosin binding properties of the N-terminal capping domain of tropomodulin 1." Biophys J. 2005; 88(1): 372-83., PMID: 15475586 kostyuas@umdnj.edu
DP00132Region 1Cozens B, Reithmeier RA. "Size and shape of rabbit skeletal muscle calsequestrin." J Biol Chem. 1984; 259(10): 6248-52., PMID: 6725251  
 Region 2, Region 3, Region 4Wang S, Trumble WR, Liao H, Wesson CR, Dunker AK, Kang CH. "Crystal structure of calsequestrin from rabbit skeletal muscle sarcoplasmic reticulum." Nat Struct Biol. 1998; 5(6): 476-83., PMID: 9628486  
 Region 1Ostwald TJ, MacLennan DH, Dorrington KJ. "Effects of cation binding on the conformation of calsequestrin and the high affinity calcium-binding protein of sarcoplasmic reticulum." J Biol Chem. 1974; 249(18): 5867-71., PMID: 4472093  
 Region 1Aaron BM, Oikawa K, Reithmeier RA, Sykes BD. "Characterization of skeletal muscle calsequestrin by 1H NMR spectroscopy." J Biol Chem. 1984; 259(19): 11876-81., PMID: 6480588  
DP00133 Parks CL, Lerch RA, Walpita P, Wang HP, Sidhu MS, Udem SA. "Comparison of predicted amino acid sequences of measles virus strains in the Edmonston vaccine lineage." J Virol. 2001; 75(2): 910-20., PMID: 11134304  
  Johansson K, Bourhis JM, Campanacci V, Cambillau C, Canard B, Longhi S. "Crystal structure of the measles virus phosphoprotein domain responsible for the induced folding of the C-terminal domain of the nucleoprotein." J Biol Chem. 2003; 278(45): 44567-73., PMID: 12944395  
  Karlin D, Ferron F, Canard B, Longhi S. "Structural disorder and modular organization in Paramyxovirinae N and P." 2003; 84(Pt 12): 3239-52., PMID: 14645906 sonia.longhi@afmb.un
iv-mrs.fr
  Longhi S, Receveur-Brechot V, Karlin D, Johansson K, Darbon H, Bhella D, Yeo R, Finet S, Canard B. "The C-terminal domain of the measles virus nucleoprotein is intrinsically disordered and folds upon binding to the C-terminal moiety of the phosphoprotein." J Biol Chem. 2003; 278(20): 18638-18648., PMID: 12621042 longhi@afmb.cnrs.mrs
.fr
  Gely S, Lowry DF, Bernard C, Jensen MR, Blackledge M, Costanzo S, Bourhis JM, Darbon H, Daughdrill G, Longhi S. "Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein." J Mol Recognit. 2010., PMID: 20058326  
 Region 1Karlin D, Longhi S, Receveur V, Canard B. "The N-terminal domain of the phosphoprotein of Morbilliviruses belongs to the natively unfolded class of proteins." Virology. 2002; 296(2): 251-62., PMID: 12069524  
 Region 4Johansson K, Bourhis JM, Campanacci V, Cambillau C, Canard B, Longhi S. "Crystal structure of the measles virus phosphoprotein domain responsible for the induced folding of the C-terminal domain of the nucleoprotein." J Biol Chem. 2003; 278(45): 44567-73., PMID: 12944395  
 Region 4Gely S, Lowry DF, Bernard C, Jensen MR, Blackledge M, Costanzo S, Bourhis JM, Darbon H, Daughdrill G, Longhi S. "Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein." J Mol Recognit. 2010., PMID: 20058326  
DP00134 Zalfa F, Bagni C. "Molecular insights into mental retardation: multiple functions for the Fragile X mental retardation protein?" Curr Issues Mol Biol. 2004; 6(2): 73-88., PMID: 15119819  
 Region 1, Region 2Adinolfi S, Bagni C, Musco G, Gibson T, Mazzarella L, Pastore A. "Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains." RNA. 1999; 5(9): 1248-58., PMID: 10496225  
DP00135 Imazu H, Sakurai H. "Saccharomyces cerevisiae heat shock transcription factor regulates cell wall remodeling in response to heat shock." Eukaryot Cell. 2005; 4(6): 1050-6., PMID: 15947197  
 Region 1Cho HS, Liu CW, Damberger FF, Pelton JG, Nelson HC, Wemmer DE. "Yeast heat shock transcription factor N-terminal activation domains are unstructured as probed by heteronuclear NMR spectroscopy." Protein Sci. 1996; 5(2): 262-9., PMID: 8745404  
DP00136Region 1, Region 2, Region 3Tarkka T, Oikarinen J, Grundstrom T. "Nucleotide and calcium-induced conformational changes in histone H1." FEBS Lett. 1997; 406(1-2): 56-60., PMID: 9109385  
 Region 1, Region 2, Region 3Cole KD, Kandala JC, Kremer E, Kistler WS. "Isolation of a genomic clone encoding the rat histone variant, H1d." Gene. 1990; 89(2): 265-9., PMID: 2373370  
DP00137Region 1Folkers PJ, Clore GM, Driscoll PC, Dodt J, Kohler S, Gronenborn AM. "Solution structure of recombinant hirudin and the Lys-47----Glu mutant: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing study." Biochemistry. 1989; 28(6): 2601-17., PMID: 2567183  
 Region 1Dodt J, Schmitz T, Schafer T, Bergmann C. "Expression, secretion and processing of hirudin in E. coli using the alkaline phosphatase signal sequence." FEBS Lett. 1986; 202(2): 373-7., PMID: 3013692  
DP00138Region 1, Region 2, Region 3Weidler M, Marx UC, Seidel G, Schafer W, Hoffmann E, Esswein A, Rosch P. "The structure of human parathyroid hormone-related protein(1-34) in near-physiological solution." FEBS Lett. 1999; 444(2-3): 239-244., PMID: 10050767  
 Region 1, Region 2, Region 3Willis KJ. "Interaction with model membrane systems induces secondary structure in amino-terminal fragments of parathyroid hormone related protein." Int J Pept Protein Res. 1994; 43(1): 23-28., PMID: 8138348  
DP00140Region 1Maguire BA, Manuilov AV, Zimmermann RA. "Differential effects of replacing Escherichia coli ribosomal protein L27 with its homologue from Aquifex aeolicus." J Bacteriol. 2001; 183(22): 6565-72., PMID: 11673426  
 Region 1Littlechild J, Malcolm A, Paterakis K, Ackermann I, Dijk J. "The tertiary structure of salt-extracted ribosomal proteins from Escherichia coli as studied by proton magnetic resonance spectroscopy and limited proteolysis experiments." Biochim Biophys Acta. 1987; 913(2): 245-55., PMID: 3297162  
DP00141 Wrana JL, Attisano L. "The Smad pathway." Cytokine Growth Factor Rev. 2000; 11(1-2): 5-13., PMID: 10708948  
 Region 1Chong PA, Ozdamar B, Wrana JL, Forman-Kay JD. "Disorder in a target for the smad2 mad homology 2 domain and its implications for binding and specificity." J Biol Chem. 2004; 279(39): 40707-14., PMID: 15231848  
DP00142 Lindner RA, Carver JA, Ehrnsperger M, Buchner J, Esposito G, Behlke J, Lutsch G, Kotlyarov A, Gaestel M. "Mouse Hsp25, a small shock protein. The role of its C-terminal extension in oligomerization and chaperone action." Eur J Biochem. 2000; 267(7): 1923-32., PMID: 10727931  
 Region 1Carver JA, Esposito G, Schwedersky G, Gaestel M. "1H NMR spectroscopy reveals that mouse Hsp25 has a flexible C-terminal extension of 18 amino acids." FEBS Lett. 1995; 369(2-3): 305-10., PMID: 7649277  
DP00143Region 1Littlechild J, Malcolm A, Paterakis K, Ackermann I, Dijk J. "The tertiary structure of salt-extracted ribosomal proteins from Escherichia coli as studied by proton magnetic resonance spectroscopy and limited proteolysis experiments." Biochim Biophys Acta. 1987; 913(2): 245-55., PMID: 3297162  
DP00144 Lanzotti DJ, Kupsco JM, Yang XC, Dominski Z, Marzluff WF, Duronio RJ. "Drosophila stem-loop binding protein intracellular localization is mediated by phosphorylation and is required for cell cycle-regulated histone mRNA expression." Mol Biol Cell. 2004; 15(3): 1112-23., PMID: 14999087  
 Region 1Thapar R, Mueller GA, Marzluff WF. "The N-terminal domain of the Drosophila histone mRNA binding protein, SLBP, is intrinsically disordered with nascent helical structure." 2004; 43(29): 9390-400., PMID: 15260482  
DP00145Region 1Venyaminov SY, Gogia ZV. "Optical characteristics of all individual proteins from the small subunit of Escherichia coli ribosomes." Eur J Biochem. 1982; 126(2): 299-309., PMID: 6751823  
DP00146Region 1Venyaminov SY, Gogia ZV. "Optical characteristics of all individual proteins from the small subunit of Escherichia coli ribosomes." Eur J Biochem. 1982; 126(2): 299-309., PMID: 6751823  
DP00147Region 1Venyaminov SY, Gogia ZV. "Optical characteristics of all individual proteins from the small subunit of Escherichia coli ribosomes." Eur J Biochem. 1982; 126(2): 299-309., PMID: 6751823  
DP00148_C004 Azoulay J, Clamme JP, Darlix JL, Roques BP, Mély Y. "Destabilization of the HIV-1 complementary sequence of TAR by the nucleocapsid protein through activation of conformational fluctuations." J Mol Biol. 2003; 326(3): 691-700., PMID: 12581633  
 Region 1Summers MF, Henderson LE, Chance MR, Bess JW Jr, South TL, Blake PR, Sagi I, Perez-Alvarado G, Sowder RC 3rd, Hare DR, et al. "Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution-state structure of the nucleocapsid protein from HIV-1." 1992; 1(5): 563-74., PMID: 1304355  
 Region 1Morellet N, Jullian N, De Rocquigny H, Maigret B, Darlix JL, Roques BP. "Determination of the structure of the nucleocapsid protein NCp7 from the human immunodeficiency virus type 1 by 1H NMR." 1992; 11(8): 3059-65., PMID: 1639074  
DP00151Region 1Heimburg T, Schuenemann J, Weber K, Geisler N. "Specific recognition of coiled coils by infrared spectroscopy: analysis of the three structural domains of type III intermediate filament proteins." Biochemistry. 1996; 35(5): 1375-82., PMID: 8634266  
 Region 1Geisler N, Plessmann U, Weber K. "The complete amino acid sequence of the major mammalian neurofilament protein (NF-L)." FEBS Lett. 1985; 182(2): 475-8., PMID: 3920075  
DP00152 Hsu HL, Yannone SM, Chen DJ. "Defining interactions between DNA-PK and ligase IV/XRCC4." DNA Repair (Amst). 2002; 1(3): 225-35., PMID: 12509254  
  Lee KJ, Jovanovic M, Udayakumar D, Bladen CL, Dynan WS. "Identification of DNA-PKcs phosphorylation sites in XRCC4 and effects of mutations at these sites on DNA end joining in a cell-free system." DNA Repair (Amst). 2004; 3(3): 267-76., PMID: 15177042  
  Modesti M, Junop MS, Ghirlando R, van de Rakt M, Gellert M, Yang W, Kanaar R. "Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive." J Mol Biol. 2003; 334(2): 215-28., PMID: 14607114  
 Region 1, Region 2, Region 3, Region 4Sibanda BL, Critchlow SE, Begun J, Pei XY, Jackson SP, Blundell TL, Pellegrini L. "Crystal structure of an Xrcc4-DNA ligase IV complex." Nat Struct Biol. 2001; 8(12): 1015-9., PMID: 11702069  
 Region 5, Region 6Junop MS, Modesti M, Guarne A, Ghirlando R, Gellert M, Yang W. "Crystal structure of the Xrcc4 DNA repair protein and implications for end joining." Embo J. 2000; 19(22): 5962-70., PMID: 11080143  
DP00153Region 7, Region 12Buhrman G, de Serrano V, Mattos C. "Organic solvents order the dynamic switch II in Ras crystals." Structure. 2003; 11(7): 747-51., PMID: 12842038  
 Region 5, Region 11, Region 13, Region 14, Region 15, Region 16, Region 19, Region 20Milburn MV, Tong L, deVos AM, Brunger A, Yamaizumi Z, Nishimura S, Kim SH. "Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins." Science. 1990; 247(4945): 939-945., PMID: 2406906  
 Region 1, Region 2, Region 3, Region 4, Region 6, Region 8, Region 9, Region 10, Region 11, Region 17, Region 18Ito Y, Yamasaki K, Iwahara J, Terada T, Kamiya A, Shirouzu M, Muto Y, Kawai G, Yokoyama S, Laue ED, Walchli M, Shibata T, Nishimura S, Miyazawa T. "Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein." Biochemistry. 1997; 36(30): 9109-9119., PMID: 9230043  
 Region 4, Region 5, Region 11, Region 18Kraulis PJ, Domaille PJ, Campbell-Burk SL, Van Aken T, Laue ED. "Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy." Biochemistry. 1994; 33(12): 3515-3531., PMID: 8142349  
DP00154Region 1, Region 2, Region 3, Region 4Farooq A, Zeng L, Yan KS, Ravichandran KS, Zhou MM. "Coupling of folding and binding in the PTB domain of the signaling protein Shc." Structure. 2003; 11(8): 905-13., PMID: 12906822  
DP00155 Fasshauer D, Eliason WK, Brünger AT, Jahn R. "Identification of a minimal core of the synaptic SNARE complex sufficient for reversible assembly and disassembly." Biochemistry. 1998; 37(29): 10354-62., PMID: 9671503  
 Region 1Margittai M, Fasshauer D, Jahn R, Langen R. "The Habc domain and the SNARE core complex are connected by a highly flexible linker." Biochemistry. 2003; 42(14): 4009-4014., PMID: 12680753  
DP00156Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Walters KJ, Lech PJ, Goh AM, Wang Q, Howley PM. "DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a." Proc Natl Acad Sci U S A. 2003; 100(22): 12694-12699., PMID: 14557549 walte048@umn.edu
DP00157Region 1, Region 2, Region 3Lilic M, Galkin VE, Orlova A, VanLoock MS, Egelman EH, Stebbins CE. "Salmonella SipA polymerizes actin by stapling filaments with nonglobular protein arms." Science. 2003; 301(5641): 1918-1921., PMID: 14512630  
DP00158 Garcia-Dominguez M, Reyes JC, Florencio FJ. "Glutamine synthetase inactivation by protein-protein interaction." Proc Natl Acad Sci U S A. 1999; 96(13): 7161-6., PMID: 10377385  
 Region 1Muro-Pastor MI, Barrera FN, Reyes JC, Florencio FJ, Neira JL. "The inactivating factor of glutamine synthetase, IF7, is a "natively unfolded" protein." Protein Sci. 2003; 12(7): 1443-1454., PMID: 12824490 jlneira@umh.es
DP00159Region 1Huber AH, Stewart DB, Laurents DV, Nelson WJ, Weis WI. "The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover." J Biol Chem. 2001; 276(15): 12301-12309., PMID: 11121423  
DP00160 Takeuchi K, Miyajima N, Kobune F, Tashiro M. "Comparative nucleotide sequence analyses of the entire genomes of B95a cell-isolated and vero cell-isolated measles viruses from the same patient." Virus Genes. 2000; 20(3): 253-7., PMID: 10949953  
 Region 1Johansson K, Bourhis JM, Campanacci V, Cambillau C, Canard B, Longhi S. "Crystal structure of the measles virus phosphoprotein domain responsible for the induced folding of the C-terminal domain of the nucleoprotein." J Biol Chem. 2003; 278(45): 44567-73., PMID: 12944395  
 Region 1Bourhis JM, Johansson K, Receveur-Brechot V, Oldfield CJ, Dunker KA, Canard B, Longhi S. "The C-terminal domain of measles virus nucleoprotein belongs to the class of intrinsically disordered proteins that fold upon binding to their physiological partner." Virus Res. 2004; 99(2): 157-67., PMID: 14749181 sonia.longhi@afmb.un
iv-mrs.fr
 Region 1Bourhis JM, Receveur-Brechot V, Oglesbee M, Zhang X, Buccellato M, Darbon H, Canard B, Finet S, Longhi S. "The intrinsically disordered C-terminal domain of the measles virus nucleoprotein interacts with the C-terminal domain of the phosphoprotein via two distinct sites and remains predominantly unfolded." Protein Sci. 2005; 14(8): 1975-92., PMID: 16046624 sonia.longhi@afmb.un
iv-mrs.fr
 Region 1Laine D, Bourhis JM, Longhi S, Flacher M, Cassard L, Canard B, Sautès-Fridman C, Rabourdin-Combe C, Valentin H. "Measles virus nucleoprotein induces cell-proliferation arrest and apoptosis through NTAIL-NR and NCORE-FcgammaRIIB1 interactions, respectively." J. Gen. Virol.. 2005; 86(Pt 6): 1771-84., PMID: 15914856  
 Region 1Zhang X, Bourhis JM, Longhi S, Carsillo T, Buccellato M, Morin B, Canard B, Oglesbee M. "Hsp72 recognizes a P binding motif in the measles virus N protein C-terminus." Virology. 2005; 337(1): 162-74., PMID: 15914229  
 Region 1Laine D, Trescol-Biemont MC, Longhi S, Libeau G, Marie JC, Vidalain PO, Azocar O, Diallo A, Canard B, Rabourdin-Combe C, Valentin H. "Measles virus (MV) nucleoprotein binds to a novel cell surface receptor distinct from FcgammaRII via its C-terminal domain: role in MV-induced immunosuppression." J Virol. 2003; 77(21): 11332-11346., PMID: 14557619  
 Region 1Longhi S, Receveur-Brechot V, Karlin D, Johansson K, Darbon H, Bhella D, Yeo R, Finet S, Canard B. "The C-terminal domain of the measles virus nucleoprotein is intrinsically disordered and folds upon binding to the C-terminal moiety of the phosphoprotein." J Biol Chem. 2003; 278(20): 18638-18648., PMID: 12621042 longhi@afmb.cnrs.mrs
.fr
 Region 1Buckland R, Gerald C, Barker D, Wild F. "Cloning and sequencing of the nucleoprotein gene of measles virus (Hallé strain)." Nucleic Acids Res. 1988; 16(24): 11821., PMID: 3211755  
 Region 1Gely S, Lowry DF, Bernard C, Jensen MR, Blackledge M, Costanzo S, Bourhis JM, Darbon H, Daughdrill G, Longhi S. "Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein." J Mol Recognit. 2010., PMID: 20058326  
DP00161Region 1Ohashi T, Hale CA, de Boer PA, Erickson HP. "Structural evidence that the P/Q domain of ZipA is an unstructured, flexible tether between the membrane and the C-terminal FtsZ-binding domain." J Bacteriol. 2002; 184(15): 4313-4315., PMID: 12107152 h.erickson@cellbio.d
uke.edu
DP00162Region 1Buck-Koehntop BA, Mascioni A, Buffy JJ, Veglia G. "Structure, dynamics, and membrane topology of stannin: a mediator of neuronal cell apoptosis induced by trimethyltin chloride." J Mol Biol. 2005; 354(3): 652-65., PMID: 16246365  
DP00163 Alves VS, Castilho BA. "Gir2 is an intrinsically unstructured protein that is present in Saccharomyces cerevisiae as a group of heterogeneously electrophoretic migrating forms." Biochem Biophys Res Commun. 2005; 332(2): 450-5., PMID: 15896712  
 Region 1Alves VS, Castilho BA. "Gir2 is an intrinsically unstructured protein that is present in Saccharomyces cerevisiae as a group of heterogeneously electrophoretic migrating forms." Biochem Biophys Res Commun. 2005; 332(2): 450-5., PMID: 15896712  
DP00164Region 1Zurdo J, Gonzalez C, Sanz JM, Rico M, Remacha M, Ballesta JP. "Structural differences between Saccharomyces cerevisiae ribosomal stalk proteins P1 and P2 support their functional diversity." Biochemistry. 2000; 39(30): 8935-43., PMID: 10913306  
DP00165 Safo MK, Mathews I, Musayev FN, di Salvo ML, Thiel DJ, Abraham DJ, Schirch V. "X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with FMN at 1.8 A resolution." Structure Fold Des. 2000; 8(7): 751-62., PMID: 10903950  
 Region 1, Region 2, Region 3, Region 4Safo MK, Musayev FN, Schirch V. "Structure of Escherichia coli pyridoxine 5'-phosphate oxidase in a tetragonal crystal form: insights into the mechanistic pathway of the enzyme." Acta Crystallogr D Biol Crystallogr. 2005; 61(Pt 5): 599-604., PMID: 15858270  
DP00166 Vassylyev DG, Takeda S, Wakatsuki S, Maeda K, Maéda Y. "Crystal structure of troponin C in complex with troponin I fragment at 2.3-A resolution." Proc Natl Acad Sci U S A. 1998; 95(9): 4847-52., PMID: 9560191  
  Li MX, Spyracopoulos L, Sykes BD. "Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac troponin-C." Biochemistry. 1999; 38(26): 8289-98., PMID: 10387074  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Takeda S, Yamashita A, Maeda K, Maeda Y. "Structure of the core domain of human cardiac troponin in the Ca(2+)-saturated form." Nature. 2003; 424(6944): 35-41., PMID: 12840750  
DP00167Region 1, Region 3Cherfils J, Menetrey J, Le Bras G, Janoueix-Lerosey I, de Gunzburg J, Garel JR, Auzat I. "Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS." EMBO J. 1997; 16(18): 5582-91., PMID: 9312017  
 Region 2, Region 4, Region 5Menetrey J, Cherfils J. "Structure of the small G protein Rap2 in a non-catalytic complex with GTP." Proteins. 1999; 37(3): 465-473., PMID: 10591105  
DP00168Region 1Musayev FN, Di Salvo ML, Ko TP, Schirch V, Safo MK. "Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase." Protein Sci. 2003; 12(7): 1455-63., PMID: 12824491  
DP00169Region 1, Region 2, Region 3, Region 4, Region 5Jimenez MA, Evangelio JA, Aranda C, Lopez-Brauet A, Andreu D, Rico M, Lagos R, Andreu JM, Monasterio O. "Helicity of alpha(404-451) and beta(394-445) tubulin C-terminal recombinant peptides." Protein Sci. 1999; 8(4): 788-799., PMID: 10211825  
DP00170 Wise MJ, Tunnacliffe A. "POPP the question: what do LEA proteins do?" Trends Plant Sci. 2004; 9(1): 13-7., PMID: 14729214  
 Region 1Soulages JL, Kim K, Arrese EL, Walters C, Cushman JC. "Conformation of a group 2 late embryogenesis abundant protein from soybean. Evidence of poly (L-proline)-type II structure." Plant Physiol. 2003; 131(3): 963-75., PMID: 12644649 jcushman@unr.edu
DP00171Region 1, Region 5Nassar N, Horn G, Herrmann C, Scherer A, McCormick F, Wittinghofer A. "The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue." Nature. 1995; 375(6532): 554-560., PMID: 7791872  
 Region 6Nassar N, Horn G, Herrmann C, Block C, Janknecht R, Wittinghofer A. "Ras/Rap effector specificity determined by charge reversal." Nat Struct Biol. 1996; 3(8): 723-729., PMID: 8756332  
 Region 2, Region 3, Region 4, Region 7, Region 8Emerson SD, Madison VS, Palermo RE, Waugh DS, Scheffler JE, Tsao KL, Kiefer SE, Liu SP, Fry DC. "Solution structure of the Ras-binding domain of c-Raf-1 and identification of its Ras interaction surface." Biochemistry. 1995; 34(21): 6911-8., PMID: 7766599  
 Region 9, Region 10, Region 11Mott HR, Carpenter JW, Zhong S, Ghosh S, Bell RM, Campbell SL. "The solution structure of the Raf-1 cysteine-rich domain: a novel ras and phospholipid binding site." Proc Natl Acad Sci U S A. 1996; 93(16): 8312-8317., PMID: 8710867  
DP00172 Chang JF, Phillips K, Lundback T, Gstaiger M, Ladbury JE, Luisi B. "Oct-1 POU and octamer DNA co-operate to recognise the Bob-1 transcription co-activator via induced folding." J Mol Biol. 1999; 288(5): 941-52., PMID: 10329190  
 Region 1, Region 2, Region 3, Region 4Chasman D, Cepek K, Sharp PA, Pabo CO. "Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface." Genes Dev. 1999; 13(20): 2650-7., PMID: 10541551  
DP00173Region 1Zhou P, Lugovskoy AA, McCarty JS, Li P, Wagner G. "Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45." Proc Natl Acad Sci U S A. 2001; 98(11): 6051-6055., PMID: 11371636 gerhard_wagner@hms.h
arvard.edu
DP00174 Steinmetz MO, Jahnke W, Towbin H, Garcia-Echeverria C, Voshol H, Muller D, van Oostrum J. "Phosphorylation disrupts the central helix in Op18/stathmin and suppresses binding to tubulin." EMBO Rep. 2001; 2(6): 505-510., PMID: 11415983  
 Region 1Honnappa S, Cutting B, Jahnke W, Seelig J, Steinmetz MO. "Thermodynamics of the Op18/stathmin-tubulin interaction." J Biol Chem. 2003; 278(40): 38926-38934., PMID: 12860982 michel.steinmetz@psi
.ch
 Region 1Steinmetz MO, Kammerer RA, Jahnke W, Goldie KN, Lustig A, van Oostrum J. "Op18/stathmin caps a kinked protofilament-like tubulin tetramer." Embo J. 2000; 19(4): 572-80., PMID: 10675326  
DP00175Region 1Knapp S, Zamai M, Volpi D, Nardese V, Avanzi N, Breton J, Plyte S, Flocco M, Marconi M, Isacchi A, Caiolfa VR. "Thermodynamics of the high-affinity interaction of TCF4 with beta-catenin." J Mol Biol. 2001; 306(5): 1179-1189., PMID: 11237626  
 Region 1Poy F, Lepourcelet M, Shivdasani RA, Eck MJ. "Structure of a human Tcf4-beta-catenin complex." Nat Struct Biol. 2001; 8(12): 1053-1057., PMID: 11713476  
DP00176Region 1, Region 2, Region 3Cobessi D, Celia H, Pattus F. "Crystal structure at high resolution of ferric-pyochelin and its membrane receptor FptA from Pseudomonas aeruginosa." J Mol Biol. 2005; 352(4): 893-904., PMID: 16139844  
DP00177 Showalter SA. "NMR assignment of the intrinsically disordered C-terminal region of Homo sapiens FCP1 in the unbound state." Biomol NMR Assign. 2009; 3(2): 179-81., PMID: 19888685  
 Region 1Nguyen BD, Abbott KL, Potempa K, Kobor MS, Archambault J, Greenblatt J, Legault P, Omichinski JG. "NMR structure of a complex containing the TFIIF subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1." Proc Natl Acad Sci U S A. 2003; 100(10): 5688-93., PMID: 12732728  
DP00179Region 1Li M, Phylip LH, Lees WE, Winther JR, Dunn BM, Wlodawer A, Kay J, Gustchina A. "The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix." Nat Struct Biol. 2000; 7(2): 113-7., PMID: 10655612  
DP00180_C003Region 1Suzuki C, Kashiwagi T, Tsuchiya F, Kunishima N, Morikawa K, Nikkuni S, Arata Y. "Circular dichroism analysis of the interaction between the alpha and beta subunits in a killer toxin produced by a halotolerant yeast, Pichia farinosa." Protein Eng. 1997; 10(2): 99-101., PMID: 9089808  
DP00181 West ML, Corden JL. "Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations." Genetics. 1995; 140(4): 1223-33., PMID: 7498765  
 Region 1, Region 2Bienkiewicz EA, Moon Woody A, Woody RW. "Conformation of the RNA polymerase II C-terminal domain: circular dichroism of long and short fragments." J Mol Biol. 2000; 297(1): 119-33., PMID: 10704311 rww@lamar.colostate.
edu
DP00182Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8Liddington RC, Yan Y, Moulai J, Sahli R, Benjamin TL, Harrison SC. "Structure of simian virus 40 at 3.8-A resolution." Nature. 1991; 354(6351): 278-84., PMID: 1659663  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8Stehle T, Gamblin SJ, Yan Y, Harrison SC. "The structure of simian virus 40 refined at 3.1 A resolution." Structure. 1996; 4(2): 165-82., PMID: 8805523  
DP00183Region 1Cobessi D, Celia H, Folschweiller N, Schalk IJ, Abdallah MA, Pattus F. "The crystal structure of the pyoverdine outer membrane receptor FpvA from Pseudomonas aeruginosa at 3.6 angstroms resolution." J Mol Biol. 2005; 347(1): 121-34., PMID: 15733922  
DP00184Region 1Rochel N, Wurtz JM, Mitschler A, Klaholz B, Moras D. "The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand." Mol Cell. 2000; 5(1): 173-9., PMID: 10678179  
DP00185 Wise MJ, Tunnacliffe A. "POPP the question: what do LEA proteins do?" Trends Plant Sci. 2004; 9(1): 13-7., PMID: 14729214  
 Region 1Soulages JL, Kim K, Walters C, Cushman JC. "Temperature-induced extended helix/random coil transitions in a group 1 late embryogenesis-abundant protein from soybean." Plant Physiol. 2002; 128(3): 822-32., PMID: 11891239 jcushman@unr.edu
DP00186 Wise MJ, Tunnacliffe A. "POPP the question: what do LEA proteins do?" Trends Plant Sci. 2004; 9(1): 13-7., PMID: 14729214  
  Chakrabortee S, Tripathi R, Watson M, Schierle GS, Kurniawan DP, Kaminski CF, Wise MJ, Tunnacliffe A. "Intrinsically disordered proteins as molecular shields." Mol Biosyst. 2011; 8(1): 210-9., PMID: 21909508  
 Region 1Goyal K, Tisi L, Basran A, Browne J, Burnell A, Zurdo J, Tunnacliffe A. "Transition from natively unfolded to folded state induced by desiccation in an anhydrobiotic nematode protein." J Biol Chem. 2003; 278(15): 12977-84., PMID: 12569097  
 Region 1Chakrabortee S, Tripathi R, Watson M, Schierle GS, Kurniawan DP, Kaminski CF, Wise MJ, Tunnacliffe A. "Intrinsically disordered proteins as molecular shields." Mol Biosyst. 2011; 8(1): 210-9., PMID: 21909508  
DP00187 Taubner LM, Bienkiewicz EA, Copie V, Caughey B. "Structure of the Flexible Amino-Terminal Domain of Prion Protein Bound to a Sulfated Glycan." J Mol Biol. 2009., PMID: 19913031  
 Region 1, Region 2Donne DG, Viles JH, Groth D, Mehlhorn I, James TL, Cohen FE, Prusiner SB, Wright PE, Dyson HJ. "Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible." Proc Natl Acad Sci U S A. 1997; 94(25): 13452-7., PMID: 9391046  
DP00188Region 1Lydakis-Simantiris N, Hutchison RS, Betts SD, Barry BA, Yocum CF. "Manganese stabilizing protein of photosystem II is a thermostable, natively unfolded polypeptide." Biochemistry. 1999; 38(1): 404-14., PMID: 9890923 cyocum@umich.edu
 Region 1Lydakis-Simantiris N, Betts SD, Yocum CF. "Leucine 245 is a critical residue for folding and function of the manganese stabilizing protein of photosystem II." Biochemistry. 1999; 38(47): 15528-35., PMID: 10569936 cyocum@umich.edu
DP00189Region 1, Region 2, Region 3, Region 4, Region 5Geyer M, Munte CE, Schorr J, Kellner R, Kalbitzer HR. "Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein." J Mol Biol. 1999; 289(1): 123-38., PMID: 10339411 hans-robert.kalbitze
r@biologie.uni-regen
sburg.de
DP00190 Ostrowski J, Barber MJ, Rueger DC, Miller BE, Siegel LM, Kredich NM. "Characterization of the flavoprotein moieties of NADPH-sulfite reductase from Salmonella typhimurium and Escherichia coli. Physicochemical and catalytic properties, amino acid sequence deduced from DNA sequence of cysJ, and comparison with NADPH-cytochrome P-450 reductase." J Biol Chem. 1989; 264(27): 15796-808., PMID: 2550423  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Gruez A, Pignol D, Zeghouf M, Coves J, Fontecave M, Ferrer JL, Fontecilla-Camps JC. "Four crystal structures of the 60 kDa flavoprotein monomer of the sulfite reductase indicate a disordered flavodoxin-like module." J Mol Biol. 2000; 299(1): 199-212., PMID: 10860732  
DP00191 Mulichak AM, Tulinsky A, Ravichandran KG. "Crystal and molecular structure of human plasminogen kringle 4 refined at 1.9-A resolution." Biochemistry. 1991; 30(43): 10576-10588., PMID: 1657148  
  Stec B, Yamano A, Whitlow M, Teeter MM. "Structure of human plasminogen kringle 4 at 1.68 a and 277 K. A possible structural role of disordered residues." Acta Crystallogr D Biol Crystallogr. 1997; 53(Pt 2): 169-178., PMID: 15299951  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10, Region 11Stec B, Yamano A, Whitlow M, Teeter MM. "Structure of human plasminogen kringle 4 at 1.68 a and 277 K. A possible structural role of disordered residues." Acta Crystallogr D Biol Crystallogr. 1997; 53(Pt 2): 169-178., PMID: 15299951  
DP00192 Holt C, Sawyer L. "Caseins as Rheomorphic Proteins: Interpretation of Primary and Secondary Structures of the alpha s1-, beta, and kappa caseins." J Chem Soc Faraday Trans. 1993; 89(15): 2683-92. 
 Region 1Syme CD, Blanch EW, Holt C, Jakes R, Goedert M, Hecht L, Barron LD. "A Raman optical activity study of rheomorphism in caseins, synucleins and tau. New insight into the structure and behaviour of natively unfolded proteins." Eur J Biochem. 2002; 269(1): 148-56., PMID: 11784308 laurence@chem.gla.ac
.uk
 Region 2, Region 3, Region 4, Region 5Raap J, Kerling KE, Vreeman HJ, Visser S. "Peptide substrates for chymosin (rennin): conformational studies of kappa-casein and some kappa-casein-related oligopeptides by circular dichroism and secondary structure prediction." Arch Biochem Biophys. 1983; 221(1): 117-24., PMID: 6402987  
DP00193Region 1Ikeguchi M, Kato S, Shimizu A, Sugai S. "Molten globule state of equine beta-lactoglobulin." Proteins. 1997; 27(4): 567-75., PMID: 9141136  
DP00194 Hersch GL, Baker TA, Sauer RT. "SspB delivery of substrates for ClpXP proteolysis probed by the design of improved degradation tags." Proc Natl Acad Sci U S A. 2004; 101(33): 12136-41., PMID: 15297609  
 Region 1Wah DA, Levchenko I, Rieckhof GE, Bolon DN, Baker TA, Sauer RT. "Flexible linkers leash the substrate binding domain of SspB to a peptide module that stabilizes delivery complexes with the AAA+ ClpXP protease." Mol Cell. 2003; 12(2): 355-63., PMID: 14536075  
DP00195Region 1Abercrombie BD, Kneale GG, Crane-Robinson C, Bradbury EM, Goodwin GH, Walker JM, Johns EW. "Studies on the conformational properties of the high-mobility-group chromosomal protein HMG 17 and its interaction with DNA." Eur J Biochem. 1978; 84(1): 173-7., PMID: 565710  
DP00196Region 1Csizmok V, Bokor M, Banki P, Klement E, Medzihradszky KF, Friedrich P, Tompa K, Tompa P. "Primary contact sites in intrinsically unstructured proteins: the case of calpastatin and microtubule-associated protein 2." Biochemistry. 2005; 44(10): 3955-64., PMID: 15751971  
DP00197Region 1Moreau M, de Cock E, Fortier PL, Garcia C, Albaret C, Blanquet S, Lallemand JY, Dardel F. "Heteronuclear NMR studies of E. coli translation initiation factor IF3. Evidence that the inter-domain region is disordered in solution." J Mol Biol. 1997; 266(1): 15-22., PMID: 9054966  
DP00198Region 1Zhu J, Winans SC. "The quorum-sensing transcriptional regulator TraR requires its cognate signaling ligand for protein folding, protease resistance, and dimerization." Proc Natl Acad Sci U S A. 2001; 98(4): 1507-12., PMID: 11171981  
DP00199 Syme CD, Blanch EW, Holt C, Jakes R, Goedert M, Hecht L, Barron LD. "A Raman optical activity study of rheomorphism in caseins, synucleins and tau. New insight into the structure and behaviour of natively unfolded proteins." Eur J Biochem. 2002; 269(1): 148-56., PMID: 11784308 laurence@chem.gla.ac
.uk
  Dev BC, Sood SM, DeWind S, Slattery CW. "Kappa-casein and beta-caseins in human milk micelles: structural studies." Arch Biochem Biophys. 1994; 314(2): 329-36., PMID: 7979373  
  Lonnerdal B, Bergstrom S, Andersson Y, Hjalmarsson K, Sundqvist AK, Hernell O. "Cloning and sequencing of a cDNA encoding human milk beta-casein." FEBS Lett. 1990; 269(1): 153-6., PMID: 2387396  
  Holt C, Sawyer L. "Caseins as Rheomorphic Proteins: Interpretation of Primary and Secondary Structures of the alpha s1-, beta, and kappa caseins." J Chem Soc Faraday Trans. 1993; 89(15): 2683-92. 
 Region 1Holt C, Sawyer L. "Primary and predicted secondary structures of the caseins in relation to their biological functions." Protein Eng. 1988; 2(4): 251-9., PMID: 3074304  
 Region 1Toyoda M, Yamauchi K. "Conformation and some properties of -casein-like fraction of human casein." Biochim Biophys Acta. 1972; 263(3): 555-63., PMID: 4624541  
DP00200 Aivazian D, Stern LJ. "Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition." Nat Struct Biol. 2000; 7(11): 1023-6., PMID: 11062556  
  Sigalov AB, Zhuravleva AV, Orekhov VY. "Binding of intrinsically disordered proteins is not necessarily accompanied by a structural transition to a folded form." Biochimie. 2007; 89(3): 419-21., PMID: 17174464  
  Baniyash M. "TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response." Nat Rev Immunol. 2004; 4(9): 675-87., PMID: 15343367  
  Weissenhorn W, Eck MJ, Harrison SC, Wiley DC. "Phosphorylated T cell receptor zeta-chain and ZAP70 tandem SH2 domains form a 1:3 complex in vitro." Eur J Biochem. 1996; 238(2): 440-5., PMID: 8681956  
 Region 1Sigalov A, Aivazian D, Stern L. "Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif." Biochemistry. 2004; 43(7): 2049-61., PMID: 14967045 Alexander.Sigalov@um
assmed.edu
DP00201Region 1, Region 2, Region 3Carbajo RJ, Silvester JA, Runswick MJ, Walker JE, Neuhaus D. "Solution structure of subunit F(6) from the peripheral stalk region of ATP synthase from bovine heart mitochondria." J Mol Biol. 2004; 342(2): 593-603., PMID: 15327958  
DP00202Region 1, Region 2Ramelot TA, Cort JR, Yee AA, Semesi A, Edwards AM, Arrowsmith CH, Kennedy MA. "NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins." Proteins. 2002; 49(2): 289-293., PMID: 12211008  
DP00205Region 1Barney BM, LoBrutto R, Francisco WA. "Characterization of a small metal binding protein from Nitrosomonas europaea." Biochemistry. 2004; 43(35): 11206-13., PMID: 15366930 wfrancisco@asu.edu
DP00206Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Keizer DW, Slupsky CM, Kalisiak M, Campbell AP, Crump MP, Sastry PA, Hazes B, Irvin RT, Sykes BD. "Structure of a pilin monomer from Pseudomonas aeruginosa: implications for the assembly of pili." J Biol Chem. 2001; 276(26): 24186-24193., PMID: 11294863 brian.sykes@ualberta
.ca
DP00207 Vanzo NF, Li YS, Py B, Blum E, Higgins CF, Raynal LC, Krisch HM, Carpousis AJ. "Ribonuclease E organizes the protein interactions in the Escherichia coli RNA degradosome." Genes Dev. 1998; 12(17): 2770-2781., PMID: 9732274  
  Leroy A, Vanzo NF, Sousa S, Dreyfus M, Carpousis AJ. "Function in Escherichia coli of the non-catalytic part of RNase E: role in the degradation of ribosome-free mRNA." Mol Microbiol. 2002; 45(5): 1231-1243., PMID: 12207692  
  Callaghan AJ, Aurikko JP, Ilag LL, Gunter Grossmann J, Chandran V, Kuhnel K, Poljak L, Carpousis AJ, Robinson CV, Symmons MF, Luisi BF. "Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E." J Mol Biol. 2004; 340(5): 965-79., PMID: 15236960  
  Kaberdin VR, Miczak A, Jakobsen JS, Lin-Chao S, McDowall KJ, von Gabain A. "The endoribonucleolytic N-terminal half of Escherichia coli RNase E is evolutionarily conserved in Synechocystis sp. and other bacteria but not the C-terminal half, which is sufficient for degradosome assembly." Proc Natl Acad Sci U S A. 1998; 95(20): 11637-11642., PMID: 9751718  
 Region 1, Region 2, Region 3, Region 4Callaghan AJ, Aurikko JP, Ilag LL, Gunter Grossmann J, Chandran V, Kuhnel K, Poljak L, Carpousis AJ, Robinson CV, Symmons MF, Luisi BF. "Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E." J Mol Biol. 2004; 340(5): 965-79., PMID: 15236960  
DP00208 Mazmanian SK, Liu G, Ton-That H, Schneewind O. "Staphylococcus aureus sortase, an enzyme that anchors surface proteins to the cell wall." Science. 1999; 285(5428): 760-3., PMID: 10427003  
 Region 1Ilangovan U, Ton-That H, Iwahara J, Schneewind O, Clubb RT. "Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus." Proc Natl Acad Sci U S A. 2001; 98(11): 6056-61., PMID: 11371637  
 Region 1Zong Y, Bice TW, Ton-That H, Schneewind O, Narayana SV. "Crystal structures of Staphylococcus aureus sortase A and its substrate complex." J Biol Chem. 2004; 279(30): 31383-9., PMID: 15117963  
DP00209Region 1Zimmermann GR, Legault P, Selsted ME, Pardi A. "Solution structure of bovine neutrophil beta-defensin-12: the peptide fold of the beta-defensins is identical to that of the classical defensins." Biochemistry. 1995; 34(41): 13663-71., PMID: 7577957  
DP00210Region 1, Region 2Yuzawa S, Yokochi M, Hatanaka H, Ogura K, Kataoka M, Miura K, Mandiyan V, Schlessinger J, Inagaki F. "Solution structure of Grb2 reveals extensive flexibility necessary for target recognition." J Mol Biol. 2001; 306(3): 527-37., PMID: 11178911  
DP00211Region 1, Region 2, Region 3Headey SJ, Keizer DW, Yao S, Brasier G, Kantharidis P, Bach LA, Norton RS. "C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II." Mol Endocrinol. 2004; 18(11): 2740-2750., PMID: 15308688  
DP00213 Kleinschmidt JA, Dingwall C, Maier G, Franke WW. "Molecular characterization of a karyophilic, histone-binding protein: cDNA cloning, amino acid sequence and expression of nuclear protein N1/N2 of Xenopus laevis." Embo J. 1986; 5(13): 3547-52., PMID: 3549279  
  Fontes MR, Teh T, Jans D, Brinkworth RI, Kobe B. "Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha." J. Biol. Chem.. 2003; 278(30): 27981-7., PMID: 12695505  
 Region 1Fontes MR, Teh T, Jans D, Brinkworth RI, Kobe B. "Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha." J. Biol. Chem.. 2003; 278(30): 27981-7., PMID: 12695505  
DP00214Region 1Fisher LW, Torchia DA, Fohr B, Young MF, Fedarko NS. "Flexible structures of SIBLING proteins, bone sialoprotein, and osteopontin." Biochem Biophys Res Commun. 2001; 280(2): 460-5., PMID: 11162539 lfisher@dir.nidcr.ni
h.gov
DP00215Region 1, Region 2, Region 3Kim AS, Kakalis LT, Abdul-Manan N, Liu GA, Rosen MK. "Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein." Nature. 2000; 404(6774): 151-8., PMID: 10724160  
DP00216Region 1Boothe JG, Sonnichsen FD, de Beus MD, Johnson-Flanagan AM. "Purification, characterization, and structural analysis of a plant low-temperature-induced protein." Plant Physiol. 1997; 113(2): 367-76., PMID: 9046590  
DP00217Region 1Hierro A, Arizmendi JM, De Las Rivas J, Urbaneja MA, Prado A, Muga A. "Structural and functional properties of Escherichia coli-derived nucleoplasmin. A comparative study of recombinant and natural proteins." Eur J Biochem. 2001; 268(6): 1739-48., PMID: 11248694 gbpmuvia@lg.ehu.es
DP00218Region 1Terrak M, Kerff F, Langsetmo K, Tao T, Dominguez R. "Structural basis of protein phosphatase 1 regulation." Nature. 2004; 429(6993): 780-4., PMID: 15164081 dominguez@bbri.org
DP00219Region 1Zhang J, Zhang L, Zhao S, Lee EY. "Identification and characterization of the human HCG V gene product as a novel inhibitor of protein phosphatase-1." Biochemistry. 1998; 37(47): 16728-34., PMID: 9843442  
DP00220 Boesze-Battaglia K, Goldberg AF. "Photoreceptor renewal: a role for peripherin/rds." Int Rev Cytol. 2002; 217: 183-225., PMID: 12019563  
 Region 1Ritter LM, Arakawa T, Goldberg AF. "Predicted and measured disorder in peripherin/rds, a retinal tetraspanin." Protein Pept Lett. 2005; 12(7): 677-86., PMID: 16522184 goldberg@oakland.edu
DP00221Region 1, Region 2Lazo ND, Downing DT. "A mixture of alpha-helical and 3(10)-helical conformations for involucrin in the human epidermal corneocyte envelope provides a scaffold for the attachment of both lipids and proteins." J Biol Chem. 1999; 274(52): 37340-4., PMID: 10601302  
DP00222Region 1Denning DP, Uversky V, Patel SS, Fink AL, Rexach M. "The Saccharomyces cerevisiae nucleoporin Nup2p is a natively unfolded protein." J Biol Chem. 2002; 277(36): 33447-55., PMID: 12065587  
DP00223Region 1Cox CJ, Dutta K, Petri ET, Hwang WC, Lin Y, Pascal SM, Basavappa R. "The regions of securin and cyclin B proteins recognized by the ubiquitination machinery are natively unfolded." FEBS Lett. 2002; 527(1-3): 303-8., PMID: 12220679  
DP00224 Corneliussen B, Thornell A, Hallberg B, Grundström T. "Helix-loop-helix transcriptional activators bind to a sequence in glucocorticoid response elements of retrovirus enhancers." J Virol. 1991; 65(11): 6084-93., PMID: 1681116  
 Region 1, Region 2, Region 3Knapp S, Zamai M, Volpi D, Nardese V, Avanzi N, Breton J, Plyte S, Flocco M, Marconi M, Isacchi A, Caiolfa VR. "Thermodynamics of the high-affinity interaction of TCF4 with beta-catenin." J Mol Biol. 2001; 306(5): 1179-1189., PMID: 11237626  
DP00225Region 1Kalthoff C, Alves J, Urbanke C, Knorr R, Ungewickell EJ. "Unusual structural organization of the endocytic proteins AP180 and epsin 1." J Biol Chem. 2002; 277(10): 8209-16., PMID: 11756460  
DP00226 Matsuzawa S, Li C, Ni CZ, Takayama S, Reed JC, Ely KR. "Structural analysis of Siah1 and its interactions with Siah-interacting protein (SIP)." J Biol Chem. 2003; 278(3): 1837-40., PMID: 12421809  
 Region 1, Region 2, Region 3, Region 4Bhattacharya S, Lee YT, Michowski W, Jastrzebska B, Filipek A, Kuznicki J, Chazin WJ. "The modular structure of SIP facilitates its role in stabilizing multiprotein assemblies." Biochemistry. 2005; 44(27): 9462-71., PMID: 15996101  
DP00227Region 1Blanch EW, Kasarda DD, Hecht L, Nielsen K, Barron LD. "New insight into the solution structures of wheat gluten proteins from Raman optical activity." Biochemistry. 2003; 42(19): 5665-73., PMID: 12741823 laurence@chem.gla.ac
.uk
DP00228Region 1Haarmann CS, Green D, Casarotto MG, Laver DR, Dulhunty AF. "The random-coil 'C' fragment of the dihydropyridine receptor II-III loop can activate or inhibit native skeletal ryanodine receptors." Biochem J. 2003; 372(Pt 2): 305-16., PMID: 12620094  
DP00229 Chambers JC, Kenan D, Martin BJ, Keene JD. "Genomic structure and amino acid sequence domains of the human La autoantigen." J Biol Chem. 1988; 263(34): 18043-51., PMID: 3192525  
  Chan EK, Sullivan KF, Tan EM. "Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding." Nucleic Acids Res. 1989; 17(6): 2233-44., PMID: 2468131  
 Region 1, Region 4Jacks A, Babon J, Kelly G, Manolaridis I, Cary PD, Curry S, Conte MR. "Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element." Structure (Camb). 2003; 11(7): 833-43., PMID: 12842046 sasi.conte@kcl.ac.uk
 Region 2, Region 3Teplova M, Yuan YR, Phan AT, Malinina L, Ilin S, Teplov A, Patel DJ. "Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen." Mol Cell. 2006; 21(1): 75-85., PMID: 16387655  
 Region 5Alfano C, Sanfelice D, Babon J, Kelly G, Jacks A, Curry S, Conte MR. "Structural analysis of cooperative RNA binding by the La motif and central RRM domain of human La protein." Nat Struct Mol Biol. 2004; 11(4): 323-9., PMID: 15004549 sasi.conte@kcl.ac.uk
DP00230 Holt LJ, Siddle K. "Grb10 and Grb14: enigmatic regulators of insulin action--and more?" Biochem J. 2005; 388(2): 393-406., PMID: 15901248  
 Region 1Moncoq K, Broutin I, Larue V, Perdereau D, Cailliau K, Browaeys-Poly E, Burnol AF, Ducruix A. "The PIR domain of Grb14 is an intrinsically unstructured protein: implication in insulin signaling." FEBS Lett. 2003; 554(3): 240-6., PMID: 14623073 broutin@pharmacie.un
iv-paris5.fr
DP00231Region 3, Region 4Dekker N, Cox M, Boelens R, Verrijzer CP, van der Vliet PC, Kaptein R. "Solution structure of the POU-specific DNA-binding domain of Oct-1." Nature. 1993; 362(6423): 852-5., PMID: 8479524  
 Region 3Klemm JD, Rould MA, Aurora R, Herr W, Pabo CO. "Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules." Cell. 1994; 77(1): 21-32., PMID: 8156594  
 Region 1, Region 2Lee L, Stollar E, Chang J, Grossmann JG, O'Brien R, Ladbury J, Carpenter B, Roberts S, Luisi B. "Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator." Biochemistry. 2001; 40(22): 6580-8., PMID: 11380252  
DP00232 Park IK, Roach P, Bondor J, Fox SP, DePaoli-Roach AA. "Molecular mechanism of the synergistic phosphorylation of phosphatase inhibitor-2. Cloning, expression, and site-directed mutagenesis of inhibitor-2." J Biol Chem. 1994; 269(2): 944-54., PMID: 8288648  
 Region 1Foulkes JG, Cohen P. "The regulation of glycogen metabolism. Purification and properties of protein phosphatase inhibitor-2 from rabbit skeletal muscle." Eur J Biochem. 1980; 105(1): 195-203., PMID: 6245879  
 Region 1Yang J, Hurley TD, DePaoli-Roach AA. "Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif." J Biol Chem. 2000; 275(30): 22635-44., PMID: 10807923  
DP00233 Doolittle RF. "Structural basis of the fibrinogen-fibrin transformation: contributions from X-ray crystallography." Blood Rev. 2003; 17(1): 33-41., PMID: 12490209  
 Region 1, Region 2Yang Z, Kollman JM, Pandi L, Doolittle RF. "Crystal structure of native chicken fibrinogen at 2.7 A resolution." Biochemistry. 2001; 40(42): 12515-23., PMID: 11601975  
DP00234 Doolittle RF. "Structural basis of the fibrinogen-fibrin transformation: contributions from X-ray crystallography." Blood Rev. 2003; 17(1): 33-41., PMID: 12490209  
 Region 1Yang Z, Kollman JM, Pandi L, Doolittle RF. "Crystal structure of native chicken fibrinogen at 2.7 A resolution." Biochemistry. 2001; 40(42): 12515-23., PMID: 11601975  
DP00235 Dulic V, Kaufmann WK, Wilson SJ, Tlsty TD, Lees E, Harper JW, Elledge SJ, Reed SI. "p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest." Cell. 1994; 76(6): 1013-23., PMID: 8137420  
 Region 1, Region 2Yang Z, Kollman JM, Pandi L, Doolittle RF. "Crystal structure of native chicken fibrinogen at 2.7 A resolution." Biochemistry. 2001; 40(42): 12515-23., PMID: 11601975  
DP00236Region 1Deibler GE, Burlin TV, Stone AL. "Three isoforms of human myelin basic protein: purification and structure." J Neurosci Res. 1995; 41(6): 819-27., PMID: 7500383  
DP00237 Baran C, Smith GS, Bamm VV, Harauz G, Lee JS. "Divalent cations induce a compaction of intrinsically disordered myelin basic protein." Biochem Biophys Res Commun. 2010; 391(1): 224-9., PMID: 19903451  
 Region 1Hill CM, Bates IR, White GF, Hallett FR, Harauz G. "Effects of the osmolyte trimethylamine-N-oxide on conformation, self-association, and two-dimensional crystallization of myelin basic protein." J Struct Biol. 2002; 139(1): 13-26., PMID: 12372316 gharauz@uoguelph.ca
 Region 2Libich DS, Harauz G. "Backbone dynamics of the 18.5 kDa isoform of myelin basic protein reveals transient alpha-helices and a calmodulin-binding site." Biophys J. 2008; 94(12): 4847-66., PMID: 18326633  
DP00238Region 1Mark WY, Liao JC, Lu Y, Ayed A, Laister R, Szymczyna B, Chakrabartty A, Arrowsmith CH. "Characterization of segments from the central region of BRCA1: an intrinsically disordered scaffold for multiple protein-protein and protein-DNA interactions?" J Mol Biol. 2005; 345(2): 275-87., PMID: 15571721 carrow@uhnres.utoron
to.ca
 Region 2, Region 3, Region 4, Region 5Gaiser OJ, Ball LJ, Schmieder P, Leitner D, Strauss H, Wahl M, Kuhne R, Oschkinat H, Heinemann U. "Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1." Biochemistry. 2004; 43(51): 15983-95., PMID: 15609993  
DP00239 Kerby RL, Hong SS, Ensign SA, Coppoc LJ, Ludden PW, Roberts GP. "Genetic and physiological characterization of the Rhodospirillum rubrum carbon monoxide dehydrogenase system." J Bacteriol. 1992; 174(16): 5284-94., PMID: 1644755  
 Region 1, Region 2Drennan CL, Heo J, Sintchak MD, Schreiter E, Ludden PW. "Life on carbon monoxide: X-ray structure of Rhodospirillum rubrum Ni-Fe-S carbon monoxide dehydrogenase." Proc Natl Acad Sci U S A. 2001; 98(21): 11973-8., PMID: 11593006  
DP00240Region 1Hughes CA, Bennett V. "Adducin: a physical model with implications for function in assembly of spectrin-actin complexes." J Biol Chem. 1995; 270(32): 18990-6., PMID: 7642559  
DP00241Region 1Hughes CA, Bennett V. "Adducin: a physical model with implications for function in assembly of spectrin-actin complexes." J Biol Chem. 1995; 270(32): 18990-6., PMID: 7642559  
DP00242Region 1Venyaminov SY, Gogia ZV. "Optical characteristics of all individual proteins from the small subunit of Escherichia coli ribosomes." Eur J Biochem. 1982; 126(2): 299-309., PMID: 6751823  
DP00243Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Ikegami T, Kuraoka I, Saijo M, Kodo N, Kyogoku Y, Morikawa K, Tanaka K, Shirakawa M. "Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA." Nat Struct Biol. 1998; 5(8): 701-706., PMID: 9699634  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Ikegami T, Kuraoka I, Saijo M, Kodo N, Kyogoku Y, Morikawa K, Tanaka K, Shirakawa M. "Resonance assignments, solution structure, and backbone dynamics of the DNA- and RPA-binding domain of human repair factor XPA." J Biochem (Tokyo). 1999; 125(3): 495-506., PMID: 10050037  
DP00245Region 1Kim C, Xuong NH, Taylor SS. "Crystal structure of a complex between the catalytic and regulatory (RIalpha) subunits of PKA." Science. 2005; 307(5710): 690-6., PMID: 15692043  
 Region 1Titani K, Sasagawa T, Ericsson LH, Kumar S, Smith SB, Krebs EG, Walsh KA. "Amino acid sequence of the regulatory subunit of bovine type I adenosine cyclic 3',5'-phosphate dependent protein kinase." Biochemistry. 1984; 23(18): 4193-9., PMID: 6487597  
DP00246Region 1Nakamura T, Hinagata J, Tanaka T, Imanishi T, Wada Y, Kodama T, Doi T. "HSP90, HSP70, and GAPDH directly interact with the cytoplasmic domain of macrophage scavenger receptors." Biochem Biophys Res Commun. 2002; 290(2): 858-64., PMID: 11785981  
DP00247Region 1, Region 2, Region 3Morth JP, Feng V, Perry LJ, Svergun DI, Tucker PA. "The crystal and solution structure of a putative transcriptional antiterminator from Mycobacterium tuberculosis." Structure (Camb). 2004; 12(9): 1595-605., PMID: 15341725  
DP00248 Kawarabayasi Y, Hino Y, Horikawa H, Yamazaki S, Haikawa Y, Jin-no K, Takahashi M, Sekine M, Baba S, Ankai A, Kosugi H, Hosoyama A, Fukui S, Nagai Y, Nishijima K, Nakazawa H, Takamiya M, Masuda S, Funahashi T, Tanaka T, Kudoh Y, Yamazaki J, Kushida N, Oguchi A, Kikuchi H, et al. "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon, Aeropyrum pernix K1." DNA Res. 1999; 6(2): 83-101, 145-52., PMID: 10382966  
 Region 1, Region 2, Region 3Bartlam M, Wang G, Yang H, Gao R, Zhao X, Xie G, Cao S, Feng Y, Rao Z. "Crystal structure of an acylpeptide hydrolase/esterase from Aeropyrum pernix K1." Structure. 2004; 12(8): 1481-8., PMID: 15296741  
DP00249 van Eerd JP, Takahashi K. "The amino acid sequence of bovine cardiac tamponin-C. Comparison with rabbit skeletal troponin-C." Biochem Biophys Res Commun. 1975; 64(1): 122-7., PMID: 1170846  
 Region 1McCubbin WD, Kay CM. "Trypsin digestion of bovine cardiac troponin C in the presence and absence of calcium." Can J Biochem Cell Biol. 1985; 63(8): 812-23., PMID: 2933134  
DP00250 Lockman H, Kaper JB. "Nucleotide sequence analysis of the A2 and B subunits of Vibrio cholerae enterotoxin." J Biol Chem. 1983; 258(22): 13722-6., PMID: 6315707  
  Lockman HA, Galen JE, Kaper JB. "Vibrio cholerae enterotoxin genes: nucleotide sequence analysis of DNA encoding ADP-ribosyltransferase." J Bacteriol. 1984; 159(3): 1086-9., PMID: 6090390  
 Region 1, Region 2, Region 3O'Neal CJ, Amaya EI, Jobling MG, Holmes RK, Hol WG. "Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism." Biochemistry. 2004; 43(13): 3772-82., PMID: 15049684  
DP00251 Chen H, Fre S, Slepnev VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P. "Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis." Nature. 1998; 394(6695): 793-7., PMID: 9723620  
 Region 1Kalthoff C, Alves J, Urbanke C, Knorr R, Ungewickell EJ. "Unusual structural organization of the endocytic proteins AP180 and epsin 1." J Biol Chem. 2002; 277(10): 8209-16., PMID: 11756460  
DP00252Region 1, Region 2, Region 3Nishio K, Morimoto Y, Ishizuka M, Ogasahara K, Tsukihara T, Yutani K. "Conformational changes in the alpha-subunit coupled to binding of the beta 2-subunit of tryptophan synthase from Escherichia coli: crystal structure of the tryptophan synthase alpha-subunit alone." Biochemistry. 2005; 44(4): 1184-92., PMID: 15667212  
DP00253 Arbuzova A, Schmitz AA, Vergères G. "Cross-talk unfolded: MARCKS proteins." Biochem J. 2002; 362(Pt 1): 1-12., PMID: 11829734  
  Seykora JT, Ravetch JV, Aderem A. "Cloning and molecular characterization of the murine macrophage "68-kDa" protein kinase C substrate and its regulation by bacterial lipopolysaccharide." Proc Natl Acad Sci U S A. 1991; 88(6): 2505-9., PMID: 2006186  
 Region 1, Region 2Matsubara M, Yamauchi E, Hayashi N, Taniguchi H. "MARCKS, a major protein kinase C substrate, assumes non-helical conformations both in solution and in complex with Ca2+-calmodulin." FEBS Lett. 1998; 421(3): 203-7., PMID: 9468306  
 Region 1, Region 2Tapp H, Al-Naggar IM, Yarmola EG, Harrison A, Shaw G, Edison AS, Bubb MR. "MARCKS is a natively unfolded protein with an inaccessible actin-binding site: evidence for long-range intramolecular interactions." J Biol Chem. 2005; 280(11): 9946-56., PMID: 15640140  
DP00254Region 1, Region 2, Region 3Kozlov G, Cheng J, Ziomek E, Banville D, Gehring K, Ekiel I. "Structural insights into molecular function of the metastasis-associated phosphatase PRL-3." J Biol Chem. 2004; 279(12): 11882-9., PMID: 14704153  
DP00255 Kozlov G, Cheng J, Ziomek E, Banville D, Gehring K, Ekiel I. "Structural insights into molecular function of the metastasis-associated phosphatase PRL-3." J Biol Chem. 2004; 279(12): 11882-9., PMID: 14704153  
 Region 1, Region 2, Region 3Laurence JS, Hallenga K, Stauffacher CV. "1H, 15N, 13C resonance assignments of the human protein tyrosine phosphatase PRL-1." J Biomol NMR. 2004; 29(3): 417-8., PMID: 15213447  
DP00256 Yamamoto A, Guacci V, Koshland D. "Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae." J Cell Biol. 1996; 133(1): 85-97., PMID: 8601616  
 Region 1Cox CJ, Dutta K, Petri ET, Hwang WC, Lin Y, Pascal SM, Basavappa R. "The regions of securin and cyclin B proteins recognized by the ubiquitination machinery are natively unfolded." FEBS Lett. 2002; 527(1-3): 303-8., PMID: 12220679  
DP00257Region 1, Region 2, Region 3, Region 4Banci L, Bertini I, Calderone V, Cramaro F, Del Conte R, Fantoni A, Mangani S, Quattrone A, Viezzoli MS. "A prokaryotic superoxide dismutase paralog lacking two Cu ligands: From largely unstructured in solution to ordered in the crystal." Proc Natl Acad Sci U S A. 2005; 102(21): 7541-6., PMID: 15897454  
DP00259 LaRue JN, Speck JC Jr. "Turkey egg white lysozyme. Preparation of the crystalline enzyme and investigation of the amino acid sequence." J Biol Chem. 1970; 245(8): 1985-91., PMID: 5440837  
 Region 1, Region 2, Region 3, Region 4, Region 5Margiolaki I, Wright JP, Fitch AN, Fox GC, Von Dreele RB. "Synchrotron X-ray powder diffraction study of hexagonal turkey egg-white lysozyme." Acta Crystallogr D Biol Crystallogr. 2005; 61(Pt 4): 423-32., PMID: 15805597  
 Region 1Howell PL, Almo SC, Parsons MR, Hajdu J, Petsko GA. "Structure determination of turkey egg-white lysozyme using Laue diffraction data." Acta Crystallogr B. 1992; 48 ( Pt 2): 200-7., PMID: 1515108  
DP00260Region 3, Region 4McEwan IJ, Dahlman-Wright K, Ford J, Wright AP. "Functional interaction of the c-Myc transactivation domain with the TATA binding protein: evidence for an induced fit model of transactivation domain folding." Biochemistry. 1996; 35(29): 9584-93., PMID: 8755740  
 Region 1, Region 2, Region 3Fladvad M, Zhou K, Moshref A, Pursglove S, Safsten P, Sunnerhagen M. "N and C-terminal sub-regions in the c-Myc transactivation region and their joint role in creating versatility in folding and binding." J Mol Biol. 2005; 346(1): 175-89., PMID: 15663936  
DP00261Region 1, Region 2Chavas LM, Tringali C, Fusi P, Venerando B, Tettamanti G, Kato R, Monti E, Wakatsuki S. "Crystal structure of the human cytosolic sialidase Neu2. Evidence for the dynamic nature of substrate recognition." J Biol Chem. 2005; 280(1): 469-75., PMID: 15501818  
DP00262 Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ. "Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation." Embo J. 2001; 20(18): 5197-206., PMID: 11566883  
  Wang GL, Jiang BH, Rue EA, Semenza GL. "Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension." Proc Natl Acad Sci U S A. 1995; 92(12): 5510-4., PMID: 7539918  
  Dames SA, Martinez-Yamout M, De Guzman RN, Dyson HJ, Wright PE. "Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response." Proc Natl Acad Sci U S A. 2002; 99(8): 5271-6., PMID: 11959977  
 Region 1, Region 2Sanchez-Puig N, Veprintsev DB, Fersht AR. "Binding of natively unfolded HIF-1alpha ODD domain to p53." Mol Cell. 2005; 17(1): 11-21., PMID: 15629713  
 Region 3Dames SA, Martinez-Yamout M, De Guzman RN, Dyson HJ, Wright PE. "Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response." Proc Natl Acad Sci U S A. 2002; 99(8): 5271-6., PMID: 11959977  
DP00263Region 1, Region 2Hodsdon ME, Cistola DP. "Discrete backbone disorder in the nuclear magnetic resonance structure of apo intestinal fatty acid-binding protein: implications for the mechanism of ligand entry." Biochemistry. 1997; 36(6): 1450-60., PMID: 9063893  
DP00265 Lopez Garcia F, Zahn R, Riek R, Wuthrich K. "NMR structure of the bovine prion protein." Proc Natl Acad Sci U S A. 2000; 97(15): 8334-9., PMID: 10899999  
 Region 1Riek R, Hornemann S, Wider G, Glockshuber R, Wuthrich K. "NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231)." FEBS Lett. 1997; 413(2): 282-8., PMID: 9280298  
DP00267 Magidovich E, Orr I, Fass D, Abdu U, Yifrach O. "Intrinsic disorder in the C-terminal domain of the Shaker voltage-activated K+ channel modulates its interaction with scaffold proteins." Proc Natl Acad Sci U S A. 2007; 104(32): 13022-7., PMID: 17666528  
 Region 1Hoshi T, Zagotta WN, Aldrich RW. "Biophysical and molecular mechanisms of Shaker potassium channel inactivation." Science. 1990; 250(4980): 533-8., PMID: 2122519  
DP00268Region 1Kang S, Prevelige PE Jr. "Domain study of bacteriophage p22 coat protein and characterization of the capsid lattice transformation by hydrogen/deuterium exchange." J Mol Biol. 2005; 347(5): 935-48., PMID: 15784254 prevelig@uab.edu
DP00269Region 1Huber AH, Stewart DB, Laurents DV, Nelson WJ, Weis WI. "The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover." J Biol Chem. 2001; 276(15): 12301-12309., PMID: 11121423  
 Region 1Oda H, Uemura T, Harada Y, Iwai Y, Takeichi M. "A Drosophila homolog of cadherin associated with armadillo and essential for embryonic cell-cell adhesion." Dev Biol. 1994; 165(2): 716-26., PMID: 7958432  
DP00270 Calcutt MJ, Kremer MT, Giblin MF, Quinn TP, Deutscher SL. "Isolation and characterization of nucleic acid-binding antibody fragments from autoimmune mice-derived bacteriophage display libraries." Gene. 1993; 137(1): 77-83., PMID: 7506692  
 Region 2Calcutt MJ, Kremer MT, Giblin MF, Quinn TP, Deutscher SL. "Isolation and characterization of nucleic acid-binding antibody fragments from autoimmune mice-derived bacteriophage display libraries." Gene. 1993; 137(1): 77-83., PMID: 7506692  
 Region 1, Region 2Schuermann JP, Prewitt SP, Davies C, Deutscher SL, Tanner JJ. "Evidence for structural plasticity of heavy chain complementarity-determining region 3 in antibody-ssDNA recognition." J Mol Biol. 2005; 347(5): 965-78., PMID: 15784256 tannerjj@missouri.ed
u
DP00271Region 1, Region 2, Region 3, Region 4, Region 5Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, Fox BA, Le Trong I, Teller DC, Okada T, Stenkamp RE, Yamamoto M, Miyano M. "Crystal structure of rhodopsin: A G protein-coupled receptor." Science. 2000; 289(5480): 739-45., PMID: 10926528  
DP00272Region 1Kerman A, Ananthanarayanan VS. "Expression and spectroscopic characterization of a large fragment of the mu-opioid receptor." Biochim Biophys Acta. 2005; 1747(1): 133-40., PMID: 15680247  
DP00273 Yatsunami K, Khorana HG. "GTPase of bovine rod outer segments: the amino acid sequence of the alpha subunit as derived from the cDNA sequence." Proc Natl Acad Sci U S A. 1985; 82(13): 4316-20., PMID: 2989813  
 Region 1Kisselev OG, Kao J, Ponder JW, Fann YC, Gautam N, Marshall GR. "Light-activated rhodopsin induces structural binding motif in G protein alpha subunit." Proc Natl Acad Sci U S A. 1998; 95(8): 4270-5., PMID: 9539726  
DP00274Region 1O'Leary JM, Hamilton JM, Deane CM, Valeyev NV, Sandell LJ, Downing AK. "Solution structure and dynamics of a prototypical chordin-like cysteine-rich repeat (von Willebrand Factor type C module) from collagen IIA." J Biol Chem. 2004; 279(51): 53857-66., PMID: 15466413  
DP00275 Parkhill J, Dougan G, James KD, Thomson NR, Pickard D, Wain J, Churcher C, Mungall KL, Bentley SD, Holden MT, Sebaihia M, Baker S, Basham D, Brooks K, Chillingworth T, Connerton P, Cronin A, Davis P, Davies RM, Dowd L, White N, Farrar J, Feltwell T, Hamlin N, Haque A, Hien TT, Holroyd S, Jagels K, Krogh A, Larsen TS, Leather S, Moule S, O'Gaora P, Parry C, Quail M, Rutherford K, Simmonds M, Skelton J, Stevens K, Whitehead S, Barrell BG. "Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18." Nature. 2001; 413(6858): 848-52., PMID: 11677608 jobby@ccmb.res.in
 Region 1, Region 2Jobby MK, Sharma Y. "Calcium-binding crystallins from Yersinia pestis. Characterization of two single betagamma-crystallin domains of a putative exported protein." J Biol Chem. 2005; 280(2): 1209-16., PMID: 15536081  
 Region 2Jobby MK, Sharma Y. "Purification of a crystallin domain of Yersinia crystallin from inclusion bodies and its comparison to native protein from the soluble fraction." Biomed Chromatogr. 2006; 20(9): 956-63., PMID: 16470515 jobby@ccmb.res.in
DP00276Region 1, Region 2Corcoran JA, Syvitski R, Top D, Epand RM, Epand RF, Jakeman D, Duncan R. "Myristoylation, a protruding loop, and structural plasticity are essential features of a nonenveloped virus fusion peptide motif." J Biol Chem. 2004; 279(49): 51386-94., PMID: 15448165  
DP00277 Glerum DM, Shtanko A, Tzagoloff A. "Characterization of COX17, a yeast gene involved in copper metabolism and assembly of cytochrome oxidase." J Biol Chem. 1996; 271(24): 14504-9., PMID: 8662933  
 Region 1, Region 2, Region 3, Region 4Abajian C, Yatsunyk LA, Ramirez BE, Rosenzweig AC. "Yeast cox17 solution structure and Copper(I) binding." J Biol Chem. 2004; 279(51): 53584-92., PMID: 15465825  
DP00278 Maza J, Das Sarma J, Koval M. "Defining a minimal motif required to prevent connexin oligomerization in the endoplasmic reticulum." J Biol Chem. 2005; 280(22): 21115-21., PMID: 15817491  
  Mitchell JA, Lye SJ. "Regulation of connexin43 expression by c-fos and c-jun in myometrial cells." Cell Commun Adhes. 2001; 8(4-6): 299-302., PMID: 12064606  
  Beyer EC, Paul DL, Goodenough DA. "Connexin43: a protein from rat heart homologous to a gap junction protein from liver." J Cell Biol. 1987; 105(6 Pt 1): 2621-9., PMID: 2826492  
  Granot I, Bechor E, Barash A, Dekel N. "Connexin43 in rat oocytes: developmental modulation of its phosphorylation." Biol Reprod. 2002; 66(3): 568-73., PMID: 11870059  
 Region 1, Region 2, Region 3Seki A, Duffy HS, Coombs W, Spray DC, Taffet SM, Delmar M. "Modifications in the biophysical properties of connexin43 channels by a peptide of the cytoplasmic loop region." Circ Res. 2004; 95(4): e22-8., PMID: 15284189  
 Region 1, Region 2, Region 3Sorgen PL, Duffy HS, Sahoo P, Coombs W, Delmar M, Spray DC. "Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1." J Biol Chem. 2004; 279(52): 54695-701., PMID: 15492000 psorgen@unmc.edu
 Region 1, Region 2, Region 3Duffy HS, Sorgen PL, Girvin ME, O'Donnell P, Coombs W, Taffet SM, Delmar M, Spray DC. "pH-dependent intramolecular binding and structure involving Cx43 cytoplasmic domains." J Biol Chem. 2002; 277(39): 36706-14., PMID: 12151412  
 Region 1, Region 2, Region 3Duffy HS, Ashton AW, O'Donnell P, Coombs W, Taffet SM, Delmar M, Spray DC. "Regulation of connexin43 protein complexes by intracellular acidification." Circ Res. 2004; 94(2): 215-22., PMID: 14699011  
DP00279 Baldisseri DM, Margolis JW, Weber DJ, Koo JH, Margolis FL. "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction." J Mol Biol. 2002; 319(3): 823-37., PMID: 12054873  
 Region 1, Region 2, Region 3Gitti RK, Wright NT, Margolis JW, Varney KM, Weber DJ, Margolis FL. "Backbone Dynamics of the Olfactory Marker Protein As Studied by (15)N NMR Relaxation Measurements." Biochemistry. 2005; 44(28): 9673-9679., PMID: 16008352  
DP00280 Shepard LA, Heuck AP, Hamman BD, Rossjohn J, Parker MW, Ryan KR, Johnson AE, Tweten RK. "Identification of a membrane-spanning domain of the thiol-activated pore-forming toxin Clostridium perfringens perfringolysin O: an alpha-helical to beta-sheet transition identified by fluorescence spectroscopy." Biochemistry. 1998; 37(41): 14563-74., PMID: 9772185  
 Region 1, Region 2Dang TX, Hotze EM, Rouiller I, Tweten RK, Wilson-Kubalek EM. "Prepore to pore transition of a cholesterol-dependent cytolysin visualized by electron microscopy." J Struct Biol. 2005; 150(1): 100-8., PMID: 15797734  
 Region 1, Region 2Shatursky O, Heuck AP, Shepard LA, Rossjohn J, Parker MW, Johnson AE, Tweten RK. "The mechanism of membrane insertion for a cholesterol-dependent cytolysin: a novel paradigm for pore-forming toxins." Cell. 1999; 99(3): 293-9., PMID: 10555145  
DP00282Region 2Banci L, Bertini I, Del Conte R, D'Onofrio M, Rosato A. "Solution structure and backbone dynamics of the Cu(I) and apo forms of the second metal-binding domain of the Menkes protein ATP7A." Biochemistry. 2004; 43(12): 3396-403., PMID: 15035611  
 Region 1, Region 2, Region 3Jones CE, Daly NL, Cobine PA, Craik DJ, Dameron CT. "Structure and metal binding studies of the second copper binding domain of the Menkes ATPase." J Struct Biol. 2003; 143(3): 209-18., PMID: 14572476  
DP00284 Mosig G, Lin GW, Franklin J, Fan WH. "Functional relationships and structural determinants of two bacteriophage T4 lysozymes: a soluble (gene e) and a baseplate-associated (gene 5) protein." New Biol. 1989; 1(2): 171-9., PMID: 2488704  
 Region 1Kanamaru S, Ishiwata Y, Suzuki T, Rossmann MG, Arisaka F. "Control of bacteriophage T4 tail lysozyme activity during the infection process." J Mol Biol. 2005; 346(4): 1013-20., PMID: 15701513  
DP00285 Anderson OD, Greene FC, Yip RE, Halford NG, Shewry PR, Malpica-Romero JM. "Nucleotide sequences of the two high-molecular-weight glutenin genes from the D-genome of a hexaploid bread wheat, Triticum aestivum L. cv Cheyenne." Nucleic Acids Res. 1989; 17(1): 461-2., PMID: 2563152  
 Region 1Blanch EW, Kasarda DD, Hecht L, Nielsen K, Barron LD. "New insight into the solution structures of wheat gluten proteins from Raman optical activity." Biochemistry. 2003; 42(19): 5665-73., PMID: 12741823 laurence@chem.gla.ac
.uk
DP00286 Zorn AM, Grow M, Patterson KD, Ebersole TA, Chen Q, Artzt K, Krieg PA. "Remarkable sequence conservation of transcripts encoding amphibian and mammalian homologues of quaking, a KH domain RNA-binding protein." Gene. 1997; 188(2): 199-206., PMID: 9133592  
 Region 1, Region 2Maguire ML, Guler-Gane G, Nietlispach D, Raine AR, Zorn AM, Standart N, Broadhurst RW. "Solution structure and backbone dynamics of the KH-QUA2 region of the Xenopus STAR/GSG quaking protein." J Mol Biol. 2005; 348(2): 265-79., PMID: 15811367  
DP00287 Iliopoulos O, Kibel A, Gray S, Kaelin WG Jr. "Tumour suppression by the human von Hippel-Lindau gene product." Nat Med. 1995; 1(8): 822-6., PMID: 7585187  
 Region 1Sutovsky H, Gazit E. "The von Hippel-Lindau tumor suppressor protein is a molten globule under native conditions: implications for its physiological activities." J Biol Chem. 2004; 279(17): 17190-6., PMID: 14963040  
DP00288 Lehnherr H, Maguin E, Jafri S, Yarmolinsky MB. "Plasmid addiction genes of bacteriophage P1: doc, which causes cell death on curing of prophage, and phd, which prevents host death when prophage is retained." J Mol Biol. 1993; 233(3): 414-28., PMID: 8411153  
 Region 1Gazit E, Sauer RT. "Stability and DNA binding of the phd protein of the phage P1 plasmid addiction system." J Biol Chem. 1999; 274(5): 2652-7., PMID: 9915794  
DP00289Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8Johnsen L, Dalhus B, Leiros I, Nissen-Meyer J. "1.6-Angstroms crystal structure of EntA-im. A bacterial immunity protein conferring immunity to the antimicrobial activity of the pediocin-like bacteriocin enterocin A." J Biol Chem. 2005; 280(19): 19045-50., PMID: 15753083  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Dalhus B, Johnsen L, Nissen-Meyer J. "Crystallization and preliminary X-ray data investigation of the bacterial enterocin A immunity protein at 1.65 A resolution." Acta Crystallogr D Biol Crystallogr. 2003; 59(Pt 7): 1291-3., PMID: 12832790  
DP00290Region 1Crepin VF, Prasannan S, Shaw RK, Wilson RK, Creasey E, Abe CM, Knutton S, Frankel G, Matthews S. "Structural and functional studies of the enteropathogenic Escherichia coli type III needle complex protein EscJ." Mol Microbiol. 2005; 55(6): 1658-70., PMID: 15752191  
DP00291Region 1Osawa M, Dace A, Tong KI, Valiveti A, Ikura M, Ames JB. "Mg2+ and Ca2+ differentially regulate DNA binding and dimerization of DREAM." J Biol Chem. 2005; 280(18): 18008-14., PMID: 15746104  
DP00292Region 1, Region 2, Region 3, Region 4Ulrich DL, Kojetin D, Bassler BL, Cavanagh J, Loria JP. "Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing." J Mol Biol. 2005; 347(2): 297-307., PMID: 15740742  
DP00293 Liao S, Shang Q, Zhang X, Zhang J, Xu C, Tu X. Biochem J. 2009 Jul 7. "PUP, a prokaryotic ubiquitin-like protein, is an an intrinsically disordered protein." Biochem J. 2009., PMID: 18832610  
 Region 1Liao S, Shang Q, Zhang X, Zhang J, Xu C, Tu X. Biochem J. 2009 Jul 7. "PUP, a prokaryotic ubiquitin-like protein, is an an intrinsically disordered protein." Biochem J. 2009., PMID: 18832610  
 Region 1Chen X, Solomon WC, Kang Y, Cerda-Maira F, Darwin KH, Walters KJ. "Prokaryotic ubiquitin-like protein pup is intrinsically disordered." J Mol Biol. 2009; 392(1): 208-17., PMID: 19607839  
DP00294 Li M, Hazelbauer GL. "Adaptational assistance in clusters of bacterial chemoreceptors." Mol Microbiol. 2005; 56(6): 1617-26., PMID: 15916610  
 Region 1Bray D. "Flexible peptides and cytoplasmic gels." Genome Biol. 2005; 6(3): 106., PMID: 15774032  
DP00295Region 1, Region 2, Region 3, Region 4Muller P, Sawaya MR, Pashkov I, Chan S, Nguyen C, Wu Y, Perry LJ, Eisenberg D. "The 1.70 angstroms X-ray crystal structure of Mycobacterium tuberculosis phosphoglycerate mutase." Acta Crystallogr D Biol Crystallogr. 2005; 61(Pt 3): 309-15., PMID: 15735341  
DP00296Region 1, Region 2Loris R, Marianovsky I, Lah J, Laeremans T, Engelberg-Kulka H, Glaser G, Muyldermans S, Wyns L. "Crystal structure of the intrinsically flexible addiction antidote MazE." J Biol Chem. 2003; 278(30): 28252-7., PMID: 12743116 reloris@vub.ac.be
 Region 1, Region 2, Region 3Lah J, Simic M, Vesnaver G, Marianovsky I, Glaser G, Engelberg-Kulka H, Loris R. "Energetics of structural transitions of the addiction antitoxin MazE: is a programmed bacterial cell death dependent on the intrinsically flexible nature of the antitoxins?" J Biol Chem. 2005; 280(17): 17397-407., PMID: 15735309  
 Region 3Kamada K, Hanaoka F, Burley SK. "Crystal structure of the MazE/MazF complex: molecular bases of antidote-toxin recognition." Mol Cell. 2003; 11(4): 875-84., PMID: 12718874  
DP00297 Muchmore SW, Sattler M, Liang H, Meadows RP, Harlan JE, Yoon HS, Nettesheim D, Chang BS, Thompson CB, Wong SL, Ng SL, Fesik SW. "X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death." Nature. 1996; 381(6580): 335-41., PMID: 8692274  
 Region 1Kang CB, Tai J, Chia J, Yoon HS. "The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)." FEBS Lett. 2005; 579(6): 1469-76., PMID: 15733859  
DP00298Region 3, Region 4, Region 5, Region 6Manion MK, O'Neill JW, Giedt CD, Kim KM, Zhang KY, Hockenbery DM. "Bcl-XL mutations suppress cellular sensitivity to antimycin A." J Biol Chem. 2004; 279(3): 2159-65., PMID: 14534311  
 Region 1, Region 2Muchmore SW, Sattler M, Liang H, Meadows RP, Harlan JE, Yoon HS, Nettesheim D, Chang BS, Thompson CB, Wong SL, Ng SL, Fesik SW. "X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death." Nature. 1996; 381(6580): 335-41., PMID: 8692274  
DP00299Region 1, Region 2, Region 3Kamada K, Hanaoka F, Burley SK. "Crystal structure of the MazE/MazF complex: molecular bases of antidote-toxin recognition." Mol Cell. 2003; 11(4): 875-84., PMID: 12718874  
DP00300 Li M, Hazelbauer GL. "Adaptational assistance in clusters of bacterial chemoreceptors." Mol Microbiol. 2005; 56(6): 1617-26., PMID: 15916610  
 Region 1Bray D. "Flexible peptides and cytoplasmic gels." Genome Biol. 2005; 6(3): 106., PMID: 15774032  
DP00301 Smith DR, Calvo JM. "Nucleotide sequence of the E coli gene coding for dihydrofolate reductase." Nucleic Acids Res. 1980; 8(10): 2255-74., PMID: 6159575  
  Venkitakrishnan RP, Zaborowski E, McElheny D, Benkovic SJ, Dyson HJ, Wright PE. "Conformational changes in the active site loops of dihydrofolate reductase during the catalytic cycle." Biochemistry. 2004; 43(51): 16046-55., PMID: 15609999  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Sawaya MR, Kraut J. "Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence." Biochemistry. 1997; 36(3): 586-603., PMID: 9012674  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Schnell JR, Dyson HJ, Wright PE. "Effect of cofactor binding and loop conformation on side chain methyl dynamics in dihydrofolate reductase." Biochemistry. 2004; 43(2): 374-83., PMID: 14717591  
DP00302 Andrykovitch M, Routzahn KM, Li M, Gu Y, Waugh DS, Ji X. "Characterization of four orthologs of stringent starvation protein A." Acta Crystallogr D Biol Crystallogr. 2003; 59(Pt 5): 881-6., PMID: 12777805  
 Region 1, Region 2, Region 3Hansen AM, Gu Y, Li M, Andrykovitch M, Waugh DS, Jin DJ, Ji X. "Structural basis for the function of stringent starvation protein a as a transcription factor." J Biol Chem. 2005; 280(17): 17380-91., PMID: 15735307  
DP00303 Edmundson AB. "Amino-Acid Sequence of Sperm Whale Myoglobin." Nature. 1965; 205(4974): 883-7. 
  Romero-Herrera A.E., Lehmann H. "Residue 122 of sperm whale and horse myoglobin." Biochim Biophys Acta. 1974; 336: 318-323. 
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8Lecomte JT, Kao YH, Cocco MJ. "The native state of apomyoglobin described by proton NMR spectroscopy: the A-B-G-H interface of wild-type sperm whale apomyoglobin." Proteins. 1996; 25(3): 267-85., PMID: 8844864  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8Kitahara R, Yamada H, Akasaka K, Wright PE. "High pressure NMR reveals that apomyoglobin is an equilibrium mixture from the native to the unfolded." J Mol Biol. 2002; 320(2): 311-9., PMID: 12079388  
DP00304Region 5, Region 6, Region 7, Region 8, Region 9, Region 10, Region 11Huang X, Begley M, Morgenstern KA, Gu Y, Rose P, Zhao H, Zhu X. "Crystal structure of an inactive Akt2 kinase domain." Structure. 2003; 11(1): 21-30., PMID: 12517337  
 Region 1, Region 2, Region 3, Region 4Yang J, Cron P, Thompson V, Good VM, Hess D, Hemmings BA, Barford D. "Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation." Mol Cell. 2002; 9(6): 1227-40., PMID: 12086620  
DP00305Region 1Wu D, Govindasamy L, Lian W, Gu Y, Kukar T, Agbandje-McKenna M, McKenna R. "Structure of human carnitine acetyltransferase. Molecular basis for fatty acyl transfer." J Biol Chem. 2003; 278(15): 13159-65., PMID: 12562770  
DP00306Region 1Natarajan K, Sawicki MW, Margulies DH, Mariuzza RA. "Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells." Biochemistry. 2000; 39(48): 14779-86., PMID: 11101293  
DP00307Region 1, Region 2Andersen G, Poterszman A, Egly JM, Moras D, Thierry JC. "The crystal structure of human cyclin H." FEBS Lett. 1996; 397(1): 65-9., PMID: 8941715  
DP00308Region 1, Region 2, Region 4Whitby FG, Phillips JD, Kushner JP, Hill CP. "Crystal structure of human uroporphyrinogen decarboxylase." Embo J. 1998; 17(9): 2463-71., PMID: 9564029  
 Region 1, Region 2, Region 3Phillips JD, Parker TL, Schubert HL, Whitby FG, Hill CP, Kushner JP. "Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase." Blood. 2001; 98(12): 3179-85., PMID: 11719352  
DP00309Region 1, Region 2, Region 3Stamos J, Sliwkowski MX, Eigenbrot C. "Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor." J Biol Chem. 2002; 277(48): 46265-72., PMID: 12196540  
DP00310Region 1, Region 2, Region 3, Region 4Song H, Mugnier P, Das AK, Webb HM, Evans DR, Tuite MF, Hemmings BA, Barford D. "The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis." Cell. 2000; 100(3): 311-21., PMID: 10676813  
DP00311Region 1, Region 2, Region 3Ding Y, Xu G, Yang M, Yao M, Gao GF, Wang L, Zhang W, Rao Z. "Crystal structure of the ectodomain of human FcalphaRI." J Biol Chem. 2003; 278(30): 27966-70., PMID: 12783876  
DP00312Region 1, Region 2, Region 3, Region 4Griffith J, Black J, Faerman C, Swenson L, Wynn M, Lu F, Lippke J, Saxena K. "The structural basis for autoinhibition of FLT3 by the juxtamembrane domain." Mol Cell. 2004; 13(2): 169-78., PMID: 14759363  
DP00313Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Prakash B, Praefcke GJ, Renault L, Wittinghofer A, Herrmann C. "Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins." Nature. 2000; 403(6769): 567-71., PMID: 10676968  
DP00314Region 4, Region 5Shiba T, Kawasaki M, Takatsu H, Nogi T, Matsugaki N, Igarashi N, Suzuki M, Kato R, Nakayama K, Wakatsuki S. "Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport." Nat Struct Biol. 2003; 10(5): 386-93., PMID: 12679809  
 Region 6, Region 7Zhu G, Zhai P, He X, Terzyan S, Zhang R, Joachimiak A, Tang J, Zhang XC. "Crystal structure of the human GGA1 GAT domain." Biochemistry. 2003; 42(21): 6392-9., PMID: 12767220  
 Region 1, Region 2, Region 3Suer S, Misra S, Saidi LF, Hurley JH. "Structure of the GAT domain of human GGA1: a syntaxin amino-terminal domain fold in an endosomal trafficking adaptor." Proc Natl Acad Sci U S A. 2003; 100(8): 4451-6., PMID: 12668765  
DP00315Region 1, Region 2, Region 3Li W, Srinivasula SM, Chai J, Li P, Wu JW, Zhang Z, Alnemri ES, Shi Y. "Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi." Nat Struct Biol. 2002; 9(6): 436-41., PMID: 11967569  
DP00317Region 5, Region 6, Region 7, Region 8, Region 9Stamos J, Lazarus RA, Yao X, Kirchhofer D, Wiesmann C. "Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor." Embo J. 2004; 23(12): 2325-35., PMID: 15167892  
 Region 1, Region 2, Region 3, Region 4Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. "Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a." Proc Natl Acad Sci U S A. 2003; 100(22): 12654-9., PMID: 14559966  
DP00318Region 1, Region 2, Region 3, Region 4, Region 5Berke IC, Boehmer T, Blobel G, Schwartz TU. "Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex." J Cell Biol. 2004; 167(4): 591-7., PMID: 15557116  
DP00319Region 1, Region 2Wang WK, Bycroft M, Foster NW, Buckle AM, Fersht AR, Chen YW. "Structure of the C-terminal sterile alpha-motif (SAM) domain of human p73 alpha." Acta Crystallogr D Biol Crystallogr. 2001; 57(Pt 4): 545-51., PMID: 11264583  
DP00320Region 1Tucker HM, Mottonen J, Goldsmith EJ, Gerard RD. "Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition." Nat Struct Biol. 1995; 2(6): 442-5., PMID: 7664104  
DP00321Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10Arita K, Hashimoto H, Shimizu T, Nakashima K, Yamada M, Sato M. "Structural basis for Ca(2+)-induced activation of human PAD4." Nat Struct Mol Biol. 2004; 11(8): 777-83., PMID: 15247907  
DP00322Region 1, Region 2Qian KC, Wang L, Hickey ER, Studts J, Barringer K, Peng C, Kronkaitis A, Li J, White A, Mische S, Farmer B. "Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase." J Biol Chem. 2005; 280(7): 6130-7., PMID: 15525646  
DP00323Region 1, Region 2, Region 3Watkins RE, Wisely GB, Moore LB, Collins JL, Lambert MH, Williams SP, Willson TM, Kliewer SA, Redinbo MR. "The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity." Science. 2001; 292(5525): 2329-33., PMID: 11408620  
DP00324Region 1, Region 2, Region 3Vitali J, Ding J, Jiang J, Zhang Y, Krainer AR, Xu RM. "Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1." Nucleic Acids Res. 2002; 30(7): 1531-8., PMID: 11917013  
DP00325 Elbrecht A, DiRenzo J, Smith RG, Shenolikar S. "Molecular cloning of protein phosphatase inhibitor-1 and its expression in rat and rabbit tissues." J Biol Chem. 1990; 265(23): 13415-8., PMID: 1696252  
 Region 1Nimmo GA, Cohen P. "The regulation of glycogen metabolism. Purification and characterisation of protein phosphatase inhibitor-1 from rabbit skeletal muscle." Eur J Biochem. 1978; 87(2): 341-51., PMID: 208844  
DP00326Region 1Gajiwala KS, Pinko C. "Structural rearrangement accompanying NAD+ synthesis within a bacterial DNA ligase crystal." Structure (Camb). 2004; 12(8): 1449-59., PMID: 15296738  
DP00327 Jansen GA, Ofman R, Ferdinandusse S, Ijlst L, Muijsers AO, Skjeldal OH, Stokke O, Jakobs C, Besley GT, Wraith JE, Wanders RJ. "Refsum disease is caused by mutations in the phytanoyl-CoA hydroxylase gene." Nat Genet. 1997; 17(2): 190-3., PMID: 9326940  
 Region 1, Region 2, Region 3, Region 4, Region 5McDonough MA, Kavanagh KL, Butler D, Searls T, Oppermann U, Schofield CJ. "Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease." J Biol Chem. 2005; 280(49): 41101-10., PMID: 16186124  
DP00328 Soeller WC, Oh CE, Kornberg TB. "Isolation of cDNAs encoding the Drosophila GAGA transcription factor." Mol Cell Biol. 1993; 13(12): 7961-70., PMID: 7504178  
 Region 1, Region 2, Region 3Agianian B, Leonard K, Bonte E, Van der Zandt H, Becker PB, Tucker PA. "The glutamine-rich domain of the Drosophila GAGA factor is necessary for amyloid fibre formation in vitro, but not for chromatin remodelling." J Mol Biol. 1999; 285(2): 527-44., PMID: 9878427  
DP00329 Holt C, Sawyer L. "Caseins as Rheomorphic Proteins: Interpretation of Primary and Secondary Structures of the alpha s1-, beta, and kappa caseins." J Chem Soc Faraday Trans. 1993; 89(15): 2683-92. 
  Yong YH, Foegeding EA. "Caseins: Utilizing Molecular Chaperone Properties to Control Protein Aggregation in Foods." J Agric Food Chem. 2009., PMID: 20025277  
 Region 1Wahlgren NM, Leonil J, Dejmek P, Drakenberg T. "Two-dimensional nuclear magnetic resonance study of the beta-casein peptide 1-25: resonance assignments and secondary structure." Biochim Biophys Acta. 1993; 1202(1): 121-8., PMID: 8373815  
 Region 2Creamer LK, Richardson T, Parry DA. "Secondary structure of bovine alpha s1- and beta-casein in solution." Arch Biochem Biophys. 1981; 211(2): 689-96., PMID: 7305393  
DP00330 Holt C, Sawyer L. "Caseins as Rheomorphic Proteins: Interpretation of Primary and Secondary Structures of the alpha s1-, beta, and kappa caseins." J Chem Soc Faraday Trans. 1993; 89(15): 2683-92. 
  Bhattacharyya J, Das KP. "Molecular chaperone-like properties of an unfolded protein, alpha(s)-casein." J Biol Chem. 1999; 274(22): 15505-9., PMID: 10336443  
 Region 1Creamer LK, Richardson T, Parry DA. "Secondary structure of bovine alpha s1- and beta-casein in solution." Arch Biochem Biophys. 1981; 211(2): 689-96., PMID: 7305393  
DP00332Region 1Fisher LW, Torchia DA, Fohr B, Young MF, Fedarko NS. "Flexible structures of SIBLING proteins, bone sialoprotein, and osteopontin." Biochem Biophys Res Commun. 2001; 280(2): 460-5., PMID: 11162539 lfisher@dir.nidcr.ni
h.gov
DP00333 McCauliffe DP, Lux FA, Lieu TS, Sanz I, Hanke J, Newkirk MM, Bachinski LL, Itoh Y, Siciliano MJ, Reichlin M, et al. "Molecular cloning, expression, and chromosome 19 localization of a human Ro/SS-A autoantigen." J Clin Invest. 1990; 85(5): 1379-91., PMID: 2332496  
 Region 1, Region 2Bouvier M, Stafford WF. "Probing the three-dimensional structure of human calreticulin." Biochemistry. 2000; 39(48): 14950-9., PMID: 11101311  
DP00334Region 1Bothner B, Lewis WS, DiGiammarino EL, Weber JD, Bothner SJ, Kriwacki RW. "Defining the molecular basis of Arf and Hdm2 interactions." J Mol Biol. 2001; 314(2): 263-77., PMID: 11718560  
 Region 2Bothner B, Aubin Y, Kriwacki RW. "Peptides derived from two dynamically disordered proteins self-assemble into amyloid-like fibrils." J Am Chem Soc. 2003; 125(11): 3200-1., PMID: 12630860  
 Region 3Uhrinova S, Uhrin D, Powers H, Watt K, Zheleva D, Fischer P, McInnes C, Barlow PN. "Structure of free MDM2 N-terminal domain reveals conformational adjustments that accompany p53-binding." J Mol Biol. 2005; 350(3): 587-98., PMID: 15953616  
DP00335Region 1Bothner B, Lewis WS, DiGiammarino EL, Weber JD, Bothner SJ, Kriwacki RW. "Defining the molecular basis of Arf and Hdm2 interactions." J Mol Biol. 2001; 314(2): 263-77., PMID: 11718560  
DP00336Region 1Bothner B, Lewis WS, DiGiammarino EL, Weber JD, Bothner SJ, Kriwacki RW. "Defining the molecular basis of Arf and Hdm2 interactions." J Mol Biol. 2001; 314(2): 263-77., PMID: 11718560  
 Region 1Bothner B, Aubin Y, Kriwacki RW. "Peptides derived from two dynamically disordered proteins self-assemble into amyloid-like fibrils." J Am Chem Soc. 2003; 125(11): 3200-1., PMID: 12630860  
DP00337Region 1Cedergren-Zeppezauer ES, Larsson G, Nyman PO, Dauter Z, Wilson KS. "Crystal structure of a dUTPase." Nature. 1992; 355(6362): 740-3., PMID: 1311056  
 Region 2Nord J, Nyman P, Larsson G, Drakenberg T. "The C-terminus of dUTPase: observation on flexibility using NMR." FEBS Lett. 2001; 492(3): 228-32., PMID: 11257499  
DP00338 Yamamoto F, Hakomori S. "Sugar-nucleotide donor specificity of histo-blood group A and B transferases is based on amino acid substitutions." J Biol Chem. 1990; 265(31): 19257-62., PMID: 2121736  
  Yamamoto F, Clausen H, White T, Marken J, Hakomori S. "Molecular genetic basis of the histo-blood group ABO system." Nature. 1990; 345(6272): 229-33., PMID: 2333095  
  Letts JA, Persson M, Schuman B, Borisova SN, Palcic MM, Evans SV. "The effect of heavy atoms on the conformation of the active-site polypeptide loop in human ABO(H) blood-group glycosyltransferase B." Acta Crystallogr D Biol Crystallogr. 2007; 63(Pt 8): 860-5., PMID: 17642512  
 Region 1, Region 2Yazer MH, Denomme GA, Rose NL, Palcic MM. "Amino-acid substitution in the disordered loop of blood group B-glycosyltransferase enzyme causes weak B phenotype." Transfusion. 2005; 45(7): 1178-82., PMID: 15987364  
 Region 1, Region 2Patenaude SI, Seto NO, Borisova SN, Szpacenko A, Marcus SL, Palcic MM, Evans SV. "The structural basis for specificity in human ABO(H) blood group biosynthesis." Nat Struct Biol. 2002; 9(9): 685-90., PMID: 12198488  
DP00339 Yamamoto F, Clausen H, White T, Marken J, Hakomori S. "Molecular genetic basis of the histo-blood group ABO system." Nature. 1990; 345(6272): 229-33., PMID: 2333095  
  Yamamoto F, Hakomori S. "Sugar-nucleotide donor specificity of histo-blood group A and B transferases is based on amino acid substitutions." J Biol Chem. 1990; 265(31): 19257-62., PMID: 2121736  
 Region 1, Region 2Yazer MH, Denomme GA, Rose NL, Palcic MM. "Amino-acid substitution in the disordered loop of blood group B-glycosyltransferase enzyme causes weak B phenotype." Transfusion. 2005; 45(7): 1178-82., PMID: 15987364  
 Region 1, Region 2Patenaude SI, Seto NO, Borisova SN, Szpacenko A, Marcus SL, Palcic MM, Evans SV. "The structural basis for specificity in human ABO(H) blood group biosynthesis." Nat Struct Biol. 2002; 9(9): 685-90., PMID: 12198488  
DP00340Region 1, Region 2, Region 3, Region 4Xiao H, Kaltashov IA. "Transient structural disorder as a facilitator of protein-ligand binding: native h/d exchange-mass spectrometry study of cellular retinoic acid binding protein I." J Am Soc Mass Spectrom. 2005; 16(6): 869-79., PMID: 15907702  
DP00341Region 1, Region 2, Region 3Huber AH, Nelson WJ, Weis WI. "Three-dimensional structure of the armadillo repeat region of beta-catenin." Cell. 1997; 90(5): 871-82., PMID: 9298899  
 Region 4Megy S, Bertho G, Gharbi-Benarous J, Baleux F, Benarous R, Girault JP. "Solution structure of a peptide derived from the oncogenic protein beta-Catenin in its phosphorylated and nonphosphorylated states." Peptides. 2005; 26(2): 227-41., PMID: 15629534  
DP00342 Tozawa K, Macdonald CJ, Penfold CN, James R, Kleanthous C, Clayden NJ, Moore GR. "Clusters in an intrinsically disordered protein create a protein-binding site: the TolB-binding region of colicin E9." Biochemistry. 2005; 44(34): 11496-507., PMID: 16114886  
 Region 1Collins ES, Whittaker SB, Tozawa K, MacDonald C, Boetzel R, Penfold CN, Reilly A, Clayden NJ, Osborne MJ, Hemmings AM, Kleanthous C, James R, Moore GR. "Structural dynamics of the membrane translocation domain of colicin E9 and its interaction with TolB." J Mol Biol. 2002; 318(3): 787-804., PMID: 12054823  
DP00343 Chen H, Lin RJ, Schiltz RL, Chakravarti D, Nash A, Nagy L, Privalsky ML, Nakatani Y, Evans RM. "Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300." Cell. 1997; 90(3): 569-80., PMID: 9267036  
 Region 1, Region 2, Region 3Demarest SJ, Martinez-Yamout M, Chung J, Chen H, Xu W, Dyson HJ, Evans RM, Wright PE. "Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators." Nature. 2002; 415(6871): 549-53., PMID: 11823864  
DP00344 Yamanaka MK, Saugstad JA, Hanson-Painton O, McCarthy BJ, Tobin SL. "Structure and expression of the Drosophila calmodulin gene." Nucleic Acids Res. 1987; 15(8): 3335-48., PMID: 3106931  
 Region 1Brokx RD, Scheek RM, Weljie AM, Vogel HJ. "Backbone dynamic properties of the central linker region of calcium-calmodulin in 35% trifluoroethanol." J Struct Biol. 2004; 146(3): 272-80., PMID: 15099569  
 Region 2Ikura M, Spera S, Barbato G, Kay LE, Krinks M, Bax A. "Secondary structure and side-chain 1H and 13C resonance assignments of calmodulin in solution by heteronuclear multidimensional NMR spectroscopy." Biochemistry. 1991; 30(38): 9216-28., PMID: 1909892  
 Region 1Barbato G, Ikura M, Kay LE, Pastor RW, Bax A. "Backbone dynamics of calmodulin studied by 15N relaxation using inverse detected two-dimensional NMR spectroscopy: the central helix is flexible." Biochemistry. 1992; 31(23): 5269-78., PMID: 1606151  
DP00345Region 1Zhang F, Yin Y, Arrowsmith CH, Ling V. "Secretion and circular dichroism analysis of the C-terminal signal peptides of HlyA and LktA." Biochemistry. 1995; 34(13): 4193-201., PMID: 7703231  
DP00346Region 1Harel M, Kryger G, Rosenberry TL, Mallender WD, Lewis T, Fletcher RJ, Guss JM, Silman I, Sussman JL. "Three-dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors." Protein Sci. 2000; 9(6): 1063-72., PMID: 10892800 Joel.Sussman@weizman
n.ac.il
DP00347 Ovchinnikov Yu A, Lipkin VM, Kumarev VP, Gubanov VV, Khramtsov NV, Akhmedov NB, Zagranichny VE, Muradov KG. "Cyclic GMP phosphodiesterase from cattle retina. Amino acid sequence of the gamma-subunit and nucleotide sequence of the corresponding cDNA." FEBS Lett. 1986; 204(2): 288-92., PMID: 3015681  
 Region 1Uversky VN, Permyakov SE, Zagranichny VE, Rodionov IL, Fink AL, Cherskaya AM, Wasserman LA, Permyakov EA. "Effect of zinc and temperature on the conformation of the gamma subunit of retinal phosphodiesterase: a natively unfolded protein." J Proteome Res. 2002; 1(2): 149-59., PMID: 12643535 vuversky@iupui.edu
DP00348Region 1, Region 3Demarest SJ, Martinez-Yamout M, Chung J, Chen H, Xu W, Dyson HJ, Evans RM, Wright PE. "Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators." Nature. 2002; 415(6871): 549-53., PMID: 11823864  
 Region 2Lin CH, Hare BJ, Wagner G, Harrison SC, Maniatis T, Fraenkel E. "A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies." Mol Cell. 2001; 8(3): 581-90., PMID: 11583620  
DP00349 Howard PK, Shaw J, Otsuka AJ. "Nucleotide sequence of the birA gene encoding the biotin operon repressor and biotin holoenzyme synthetase functions of Escherichia coli." Gene. 1985; 35(3): 321-31., PMID: 3899863  
 Region 1, Region 4, Region 6Kwon K, Streaker ED, Ruparelia S, Beckett D. "Multiple disordered loops function in corepressor-induced dimerization of the biotin repressor." J Mol Biol. 2000; 304(5): 821-33., PMID: 11124029  
 Region 2, Region 8Wilson KP, Shewchuk LM, Brennan RG, Otsuka AJ, Matthews BW. "Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains." Proc Natl Acad Sci U S A. 1992; 89(19): 9257-61., PMID: 1409631  
 Region 3, Region 5, Region 7Streaker ED, Beckett D. "Ligand-linked structural changes in the Escherichia coli biotin repressor: the significance of surface loops for binding and allostery." J Mol Biol. 1999; 292(3): 619-32., PMID: 10497026  
DP00350Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Griswold IJ, Zhou H, Matison M, Swanson RV, McIntosh LP, Simon MI, Dahlquist FW. "The solution structure and interactions of CheW from Thermotoga maritima." Nat Struct Biol. 2002; 9(2): 121-5., PMID: 11799399  
 Region 5, Region 6, Region 7Griswold IJ, Dahlquist FW. "The dynamic behavior of CheW from Thermotoga maritima in solution, as determined by nuclear magnetic resonance: implications for potential protein-protein interaction sites." Biophys Chem. 2002; 101-102: 359-73., PMID: 12488014  
DP00351 Morgan JR, Prasad K, Jin S, Augustine GJ, Lafer EM. "Uncoating of clathrin-coated vesicles in presynaptic terminals: roles for Hsc70 and auxilin." Neuron. 2001; 32(2): 289-300., PMID: 11683998  
 Region 1Scheele U, Alves J, Frank R, Düwel M, Kalthoff C, Ungewickell E. Scheele U, Alves J, Frank R, Düwel M, Kalthoff C, Ungewickell E. "Molecular and functional characterization of clathrin- and AP-2 binding determinants within a disordered domain of auxilin." J Biol Chem. 2003; 278(28): 25357-25368., PMID: 12732633  
DP00352 Ramadurai L, Jayaswal RK. "Molecular cloning, sequencing, and expression of lytM, a unique autolytic gene of Staphylococcus aureus." J Bacteriol. 1997; 179(11): 3625-31., PMID: 9171409  
 Region 1, Region 2, Region 3, Region 4Firczuk M, Mucha A, Bochtler M. "Crystal Structures of Active LytM." J Mol Biol. 2005., PMID: 16269153  
DP00353 Wickner RB, Taylor KL, Edskes HK, Maddelein ML, Moriyama H, Roberts BT. "Prions of yeast as heritable amyloidoses." J Struct Biol. 2000; 130(2-3): 310-22., PMID: 10940235  
 Region 1Thual C, Komar AA, Bousset L, Fernandez-Bellot E, Cullin C, Melki R. "Structural characterization of Saccharomyces cerevisiae prion-like protein Ure2." 1999; 274(19): 13666-74., PMID: 10224139  
 Region 1Thual C, Bousset L, Komar AA, Walter S, Buchner J, Cullin C, Melki R. "Stability, folding, dimerization, and assembly properties of the yeast prion Ure2p." Biochemistry. 2001; 40(6): 1764-73., PMID: 11327838  
 Region 1Pierce MM, Baxa U, Steven AC, Bax A, Wickner RB. "Is the prion domain of soluble Ure2p unstructured?" Biochemistry. 2005; 44(1): 321-8., PMID: 15628874  
DP00354 Kim JH, Singvall J, Schwarz-Linek U, Johnson BJ, Potts JR, Hook M. "BBK32, a fibronectin binding MSCRAMM from Borrelia burgdorferi, contains a disordered region that undergoes a conformational change on ligand binding." J Biol Chem. 2004; 279(40): 41706-14., PMID: 15292204  
 Region 1Kim JH, Singvall J, Schwarz-Linek U, Johnson BJ, Potts JR, Hook M. "BBK32, a fibronectin binding MSCRAMM from Borrelia burgdorferi, contains a disordered region that undergoes a conformational change on ligand binding." J Biol Chem. 2004; 279(40): 41706-14., PMID: 15292204  
DP00355 Rall SC Jr, Weisgraber KH, Mahley RW. "Human apolipoprotein E. The complete amino acid sequence." J Biol Chem. 1982; 257(8): 4171-8., PMID: 7068630  
 Region 1, Region 2, Region 3Segelke BW, Forstner M, Knapp M, Trakhanov SD, Parkin S, Newhouse YM, Bellamy HD, Weisgraber KH, Rupp B. "Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: implications for lipid binding." Protein Sci. 2000; 9(5): 886-97., PMID: 10850798  
 Region 1, Region 2, Region 3Wilson C, Wardell MR, Weisgraber KH, Mahley RW, Agard DA. "Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E." Science. 1991; 252(5014): 1817-22., PMID: 2063194  
DP00356 De Guzman RN, Martinez-Yamout MA, Dyson HJ, Wright PE. "Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites." J Biol Chem. 2004; 279(4): 3042-9., PMID: 14594809  
 Region 1De Guzman RN, Martinez-Yamout MA, Dyson HJ, Wright PE. "Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites." J Biol Chem. 2004; 279(4): 3042-9., PMID: 14594809  
DP00357 Paunola E, Mattila PK, Lappalainen P. "WH2 domain: a small, versatile adapter for actin monomers." FEBS Letters. ; 513(1): 92-7., PMID: 11911886  
  Hertzog M, van Heijenoort C, Didry D, Gaudier M, Coutant J, Gigant B, Didelot G, Preat T, Knossow M, Guittet E, Carlier MF. "The beta-thymosin/WH2 domain; structural basis for the switch from inhibition to promotion of actin assembly." Cell. 2004; 117(5): 611-23., PMID: 15163409  
  Safer D, Sosnick TR, Elzinga M. "Thymosin beta 4 binds actin in an extended conformation and contacts both the barbed and pointed ends." Biochemistry. 1997; 36(19): 5806-16., PMID: 9153421  
  Bubb MR. "Thymosin beta 4 interactions." Vitam Horm. 2003; 66: 297-316., PMID: 12852258  
 Region 1Domanski M, Hertzog M, Coutant J, Gutsche-Perelroizen I, Bontems F, Carlier MF, Guittet E, van Heijenoort C. "Coupling of folding and binding of thymosin beta4 upon interaction with monomeric actin monitored by nuclear magnetic resonance." J Biol Chem. 2004; 279(22): 23637-45., PMID: 15039431 carine@icsn.cnrs-gif
.fr
 Region 1Czisch M, Schleicher M, Hörger S, Voelter W, Holak TA. "Conformation of thymosin beta 4 in water determined by NMR spectroscopy." Eur J Biochem. 1993; 218(2): 335-44., PMID: 8269922  
DP00358 Weaver AJ, Sullivan WP, Felts SJ, Owen BA, Toft DO. "Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone." J Biol Chem. 2000; 275(30): 23045-52., PMID: 10811660  
 Region 1Weikl T, Abelmann K, Buchner J. "An unstructured C-terminal region of the Hsp90 co-chaperone p23 is important for its chaperone function." J Mol Biol. 1999; 293(3): 685-91., PMID: 10543959  
 Region 2Weaver AJ, Sullivan WP, Felts SJ, Owen BA, Toft DO. "Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone." J Biol Chem. 2000; 275(30): 23045-52., PMID: 10811660  
DP00359 Graciet E, Lebreton S, Gontero B. "Emergence of new regulatory mechanisms in the Benson-Calvin pathway via protein-protein interactions: a glyceraldehyde-3-phosphate dehydrogenase/CP12/phosphoribulokinase complex." J Exp Bot. 2004; 55(400): 1245-54., PMID: 15047759  
 Region 1, Region 2, Region 3Graciet E, Gans P, Wedel N, Lebreton S, Camadro JM, Gontero B. "The small protein CP12: a protein linker for supramolecular complex assembly." Biochemistry. 2003; 42(27): 8163-70., PMID: 12846565  
 Region 1, Region 2, Region 3Gardebien F, Thangudu RR, Gontero B, Offmann B. "Construction of a 3D model of CP12, a protein linker." J Mol Graph Model. 2006; 25(2): 186-95., PMID: 16427344  
 Region 1, Region 2, Region 3Delobel A, Graciet E, Andreescu S, Gontero B, Halgand F, Laprévote O. "Mass spectrometric analysis of the interactions between CP12, a chloroplast protein, and metal ions: a possible regulatory role within a PRK/GAPDH/CP12 complex." Rapid Commun Mass Spectrom. 2005; 19(22): 3379-88., PMID: 16259044  
DP00360 King SM. "The dynein microtubule motor." Biochim Biophys Acta. 2000; 1496(1): 60-75., PMID: 10722877  
 Region 1Nyarko A, Hare M, Hays TS, Barbar E. "The intermediate chain of cytoplasmic dynein is partially disordered and gains structure upon binding to light-chain LC8." Biochemistry. 2004; 43(49): 15595-603., PMID: 15581372 barbare@science.oreg
onstate.edu
 Region 1Makokha M, Hare M, Li M, Hays T, Barbar E. "Interactions of cytoplasmic dynein light chains Tctex-1 and LC8 with the intermediate chain IC74." Biochemistry. 2002; 41(13): 4302-11., PMID: 11914076 barbare@science.oreg
onstate.edu
 Region 1Barbar E, Hare M. "Characterization of the cargo attachment complex of cytoplasmic dynein using NMR and mass spectrometry." Methods Enzymol. 2004; 380: 219-41., PMID: 15051340 barbare@science.oreg
onstate.edu
DP00361Region 1, Region 2, Region 3Luz JG, Hassig CA, Pickle C, Godzik A, Meyer BJ, Wilson IA. "XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators." Genes Dev. 2003; 17(8): 977-90., PMID: 12672694  
DP00363Region 1Peneff C, Ferrari P, Charrier V, Taburet Y, Monnier C, Zamboni V, Winter J, Harnois M, Fassy F, Bourne Y. "Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture." Embo J. 2001; 20(22): 6191-202., PMID: 11707391  
DP00363_A002Region 1Peneff C, Ferrari P, Charrier V, Taburet Y, Monnier C, Zamboni V, Winter J, Harnois M, Fassy F, Bourne Y. "Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture." Embo J. 2001; 20(22): 6191-202., PMID: 11707391  
DP00364Region 1Yu Y, Li S, Xu X, Li Y, Guan K, Arnold E, Ding J. "Structural basis for the unique biological function of small GTPase RHEB." J Biol Chem. 2005; 280(17): 17093-100., PMID: 15728574  
DP00365 Chinkers M. "Protein phosphatase 5 in signal transduction." Trends Endocrinol Metab. 2001; 12(1): 28-32., PMID: 11137038  
 Region 1Cliff MJ, Williams MA, Brooke-Smith J, Barford D, Ladbury JE. "Molecular recognition via coupled folding and binding in a TPR domain." J Mol Biol. 2005; 346(3): 717-32., PMID: 15713458 j.ladbury@biochem.uc
l.ac.uk
DP00367 Zambelli B, Stola M, Musiani F, De Vriendt K, Samyn B, Devreese B, Van Beeumen J, Turano P, Dikiy A, Bryant DA, Ciurli S. "UreG, a chaperone in the urease assembly process, is an intrinsically unstructured GTPase that specifically binds Zn2+." 2005; 280(6): 4684-95., PMID: 15542602 stefano.ciurli@unibo
.it
  Neyroz P, Zambelli B, Ciurli S. "Intrinsically disordered structure of Bacillus pasteurii UreG as revealed by steady-state and time-resolved fluorescence spectroscopy." Biochemistry. 2006; 45(29): 8918-30., PMID: 16846235 stefano.ciurli@unibo
.it
 Region 1Zambelli B, Stola M, Musiani F, De Vriendt K, Samyn B, Devreese B, Van Beeumen J, Turano P, Dikiy A, Bryant DA, Ciurli S. "UreG, a chaperone in the urease assembly process, is an intrinsically unstructured GTPase that specifically binds Zn2+." 2005; 280(6): 4684-95., PMID: 15542602 stefano.ciurli@unibo
.it
DP00372 Sunde M, McGrath KC, Young L, Matthews JM, Chua EL, Mackay JP, Death AK. "TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer." Cancer Res. 2004; 64(8): 2766-73., PMID: 15087392  
  Gall C, Xu H, Brickenden A, Ai X, Choy WY. "The intrinsically disordered TC-1 interacts with Chibby via regions with high helical propensity." Protein Sci. 2007; 16(11): 2510-8., PMID: 17905836  
 Region 1Sunde M, McGrath KC, Young L, Matthews JM, Chua EL, Mackay JP, Death AK. "TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer." Cancer Res. 2004; 64(8): 2766-73., PMID: 15087392  
DP00373 Derbyshire DJ, Basu BP, Serpell LC, Joo WS, Date T, Iwabuchi K, Doherty AJ. "Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor." EMBO J. 2002; 21(14): 3863-72., PMID: 12110597  
 Region 1Yang Y, Poncet J, Garnier J, Zatylny C, Bachere E, Aumelas A. "Solution structure of the recombinant penaeidin-3, a shrimp antimicrobial peptide." J Biol Chem. 2003; 278(38): 36859-67., PMID: 12842879  
DP00374Region 1Wang G, Wylie GP, Twigg PD, Caspar DL, Murphy JR, Logan TM. "Solution structure and peptide binding studies of the C-terminal src homology 3-like domain of the diphtheria toxin repressor protein." Proc Natl Acad Sci U S A. 1999; 96(11): 6119-24., PMID: 10339551  
DP00375Region 1, Region 2, Region 3, Region 4Golan G, Zharkov DO, Feinberg H, Fernandes AS, Zaika EI, Kycia JH, Grollman AP, Shoham G. "Structure of the uncomplexed DNA repair enzyme endonuclease VIII indicates significant interdomain flexibility." Nucleic Acids Res. 2005; 33(15): 5006-16., PMID: 16145054  
DP00376Region 1, Region 2Westman BJ, Perdomo J, Matthews JM, Crossley M, Mackay JP. "Structural studies on a protein-binding zinc-finger domain of Eos reveal both similarities and differences to classical zinc fingers." Biochemistry. 2004; 43(42): 13318-27., PMID: 15491138  
DP00377Region 1Smith MN, Crane RA, Keates RA, Wood JM. "Overexpression, purification, and characterization of ProQ, a posttranslational regulator for osmoregulatory transporter ProP of Escherichia coli." Biochemistry. 2004; 43(41): 12979-89., PMID: 15476391  
DP00378Region 1, Region 2, Region 3, Region 4Oka S, Shiraishi Y, Yoshida T, Ohkubo T, Sugiura Y, Kobayashi Y. "NMR structure of transcription factor Sp1 DNA binding domain." Biochemistry. 2004; 43(51): 16027-35., PMID: 15609997  
DP00379Region 1, Region 2, Region 3Chatwood LL, Müller J, Gross JD, Wagner G, Lippard SJ. "NMR structure of the flavin domain from soluble methane monooxygenase reductase from Methylococcus capsulatus (Bath)." Biochemistry. 2004; 43(38): 11983-91., PMID: 15379538  
DP00380Region 1Sprules T, Kawulka KE, Vederas JC. "NMR solution structure of ImB2, a protein conferring immunity to antimicrobial activity of the type IIa bacteriocin, carnobacteriocin B2." Biochemistry. 2004; 43(37): 11740-9., PMID: 15362858  
DP00381 Hankinson O. "The aryl hydrocarbon receptor complex." Annu Rev Pharmacol Toxicol. 1995; 35: 307-40., PMID: 7598497  
 Region 1Watt K, Jess TJ, Kelly SM, Price NC, McEwan IJ. "Induced alpha-helix structure in the aryl hydrocarbon receptor transactivation domain modulates protein-protein interactions." Biochemistry. 2005; 44(2): 734-43., PMID: 15641800 iain.mcewan@abdn.ac.
uk
DP00382Region 1, Region 2Sidote DJ, Heideker J, Hoffman DW. "Crystal structure of archaeal ribonuclease P protein aRpp29 from Archaeoglobus fulgidus." Biochemistry. 2004; 43(44): 14128-38., PMID: 15518563  
DP00383Region 1, Region 2, Region 3Larson HN, Weiner H, Hurley TD. "Disruption of the coenzyme binding site and dimer interface revealed in the crystal structure of mitochondrial aldehyde dehydrogenase "Asian" variant." J Biol Chem. 2005; 280(34): 30550-6., PMID: 15983043  
DP00384Region 1, Region 2, Region 3, Region 4Knapp S, Muller S, Digilio G, Bonaldi T, Bianchi ME, Musco G. "The long acidic tail of high mobility group box 1 (HMGB1) protein forms an extended and flexible structure that interacts with specific residues within and between the HMG boxes." Biochemistry. 2004; 43(38): 11992-7., PMID: 15379539  
DP00385Region 1, Region 2Dajani R, Fraser E, Roe SM, Young N, Good V, Dale TC, Pearl LH. "Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition." Cell. 2001; 105(6): 721-32., PMID: 11440715  
 Region 3Dajani R, Fraser E, Roe SM, Yeo M, Good VM, Thompson V, Dale TC, Pearl LH. "Structural basis for recruitment of glycogen synthase kinase 3beta to the axin-APC scaffold complex." EMBO J. 2003; 22(3): 494-501., PMID: 12554650  
 Region 4ter Haar E, Coll JT, Austen DA, Hsiao HM, Swenson L, Jain J. "Structure of GSK3beta reveals a primed phosphorylation mechanism." Nat Struct Biol. 2001; 8(7): 593-6., PMID: 11427888  
DP00386_C001Region 1Zhu HL, Atkinson D. "Conformation and lipid binding of the N-terminal (1-44) domain of human apolipoprotein A-I." Biochemistry. 2004; 43(41): 13156-64., PMID: 15476409  
 Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10, Region 11, Region 12Okon M, Frank PG, Marcel YL, Cushley RJ. "Heteronuclear NMR studies of human serum apolipoprotein A-I. Part I. Secondary structure in lipid-mimetic solution." FEBS Lett. 2002; 517(1-3): 139-43., PMID: 12062424  
DP00387Region 1Henkels CH, Kurz JC, Fierke CA, Oas TG. "Linked folding and anion binding of the Bacillus subtilis ribonuclease P protein." Biochemistry. 2001; 40(9): 2777-89., PMID: 11258888  
 Region 1Henkels CH, Oas TG. "Thermodynamic Characterization of the Osmolyte- and Ligand-Folded States of Bacillus subtilis Ribonuclease P Protein." Biochemistry. 2005; 44(39): 13014-26., PMID: 16185070  
DP00388Region 1, Region 2, Region 3Jing W, Hunter HN, Tanabe H, Ouellette AJ, Vogel HJ. "Solution structure of cryptdin-4, a mouse paneth cell alpha-defensin." Biochemistry. 2004; 43(50): 15759-66., PMID: 15595831  
DP00389 Felmlee T, Pellett S, Welch RA. "Nucleotide sequence of an Escherichia coli chromosomal hemolysin." J Bacteriol. 1985; 163(1): 94-105., PMID: 3891743  
 Region 1Zhang F, Yin Y, Arrowsmith CH, Ling V. "Secretion and circular dichroism analysis of the C-terminal signal peptides of HlyA and LktA." Biochemistry. 1995; 34(13): 4193-201., PMID: 7703231  
DP00390Region 1, Region 2, Region 3Han M, Gurevich VV, Vishnivetskiy SA, Sigler PB, Schubert C. "Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane Translocation." Structure (Camb). 2001; 9(9): 869-80., PMID: 11566136  
 Region 4, Region 5Kang DS, Kern RC, Puthenveedu MA, von Zastrow M, Williams JC, Benovic JL. "Structure of an arrestin2/clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking." J Biol Chem. 2009., PMID: 19710023  
DP00392Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Mazza C, Ohno M, Segref A, Mattaj IW, Cusack S. "Crystal structure of the human nuclear cap binding complex." Mol Cell. 2001; 8(2): 383-96., PMID: 11545740  
DP00393 Izaurralde E, Lewis J, Gamberi C, Jarmolowski A, McGuigan C, Mattaj IW. "A cap-binding protein complex mediating U snRNA export." Nature. 1995; 376(6542): 709-12., PMID: 7651522  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Mazza C, Ohno M, Segref A, Mattaj IW, Cusack S. "Crystal structure of the human nuclear cap binding complex." Mol Cell. 2001; 8(2): 383-96., PMID: 11545740  
DP00394 Ikemura H, Takagi H, Inouye M. "Requirement of pro-sequence for the production of active subtilisin E in Escherichia coli." J Biol Chem. 1987; 262(16): 7859-64., PMID: 3108260  
  Subbian E, Yabuta Y, Shinde UP. "Folding pathway mediated by an intramolecular chaperone: intrinsically unstructured propeptide modulates stochastic activation of subtilisin." J Mol Biol. 2005; 347(2): 367-83., PMID: 15740747  
 Region 1Buevich AV, Shinde UP, Inouye M, Baum J. "Backbone dynamics of the natively unfolded pro-peptide of subtilisin by heteronuclear NMR relaxation studies." J Biomol NMR. 2001; 20(3): 233-49., PMID: 11519747  
DP00395Region 1Drum CL, Yan SZ, Bard J, Shen YQ, Lu D, Soelaiman S, Grabarek Z, Bohm A, Tang WJ. "Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin." Nature. 2002; 415(6870): 396-402., PMID: 11807546  
DP00396Region 1, Region 2, Region 3Kong C, Ito K, Walsh MA, Wada M, Liu Y, Kumar S, Barford D, Nakamura Y, Song H. "Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe." Mol Cell. 2004; 14(2): 233-45., PMID: 15099522  
DP00397Region 1Pedersen LC, Dong J, Taniguchi F, Kitagawa H, Krahn JM, Pedersen LG, Sugahara K, Negishi M. "Crystal structure of an alpha 1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis." J Biol Chem. 2003; 278(16): 14420-8., PMID: 12562774  
DP00398Region 1, Region 2, Region 3, Region 4Pang SS, Duggleby RG, Guddat LW. "Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors." J Mol Biol. 2002; 317(2): 249-62., PMID: 11902841  
DP00399Region 1, Region 2, Region 3, Region 4Whitby FG, Luecke H, Kuhn P, Somoza JR, Huete-Perez JA, Phillips JD, Hill CP, Fletterick RJ, Wang CC. "Crystal structure of Tritrichomonas foetus inosine-5'-monophosphate dehydrogenase and the enzyme-product complex." Biochemistry. 1997; 36(35): 10666-74., PMID: 9271497  
DP00400Region 1, Region 2, Region 3Chang G, Roth CB. "Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters." Science. 2001; 293(5536): 1793-800., PMID: 11546864 gchang@scripps.edu
DP00401Region 1, Region 2Higgins MK, Bokma E, Koronakis E, Hughes C, Koronakis V. "Structure of the periplasmic component of a bacterial drug efflux pump." Proc Natl Acad Sci U S A. 2004; 101(27): 9994-9., PMID: 15226509  
DP00404 Her C, Wood TC, Eichler EE, Mohrenweiser HW, Ramagli LS, Siciliano MJ, Weinshilboum RM. "Human hydroxysteroid sulfotransferase SULT2B1: two enzymes encoded by a single chromosome 19 gene." Genomics. 1998; 53(3): 284-95., PMID: 9799594  
 Region 1Lee KA, Fuda H, Lee YC, Negishi M, Strott CA, Pedersen LC. "Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms." J Biol Chem. 2003; 278(45): 44593-9., PMID: 12923182  
DP00404_A002 Her C, Wood TC, Eichler EE, Mohrenweiser HW, Ramagli LS, Siciliano MJ, Weinshilboum RM. "Human hydroxysteroid sulfotransferase SULT2B1: two enzymes encoded by a single chromosome 19 gene." Genomics. 1998; 53(3): 284-95., PMID: 9799594  
 Region 1, Region 2Lee KA, Fuda H, Lee YC, Negishi M, Strott CA, Pedersen LC. "Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms." J Biol Chem. 2003; 278(45): 44593-9., PMID: 12923182  
DP00406 Phillips SE. "Turning up the HEAT on translation." Structure. 2006; 14(5): 806-7., PMID: 16698542  
 Region 1Phillips SE. "Turning up the HEAT on translation." Structure. 2006; 14(5): 806-7., PMID: 16698542  
DP00407Region 1, Region 2McEvoy MM, Muhandiram DR, Kay LE, Dahlquist FW. "Structure and dynamics of a CheY-binding domain of the chemotaxis kinase CheA determined by nuclear magnetic resonance spectroscopy." Biochemistry. 1996; 35(18): 5633-40., PMID: 8639521  
DP00408 Lapouge K, Smith SJ, Walker PA, Gamblin SJ, Smerdon SJ, Rittinger K. "Structure of the TPR domain of p67phox in complex with Rac.GTP." Mol Cell. 2000; 6(4): 899-907., PMID: 11090627  
 Region 1, Region 2, Region 3Fiegen D, Haeusler LC, Blumenstein L, Herbrand U, Dvorsky R, Vetter IR, Ahmadian MR. "Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase." J Biol Chem. 2004; 279(6): 4743-9., PMID: 14625275  
DP00410_C011 Maignan S, Guilloteau JP, Zhou-Liu Q, Clément-Mella C, Mikol V. "Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases." J. Mol. Biol.. 1998; 282(2): 359-68., PMID: 9735293  
 Region 1Maignan S, Guilloteau JP, Zhou-Liu Q, Clément-Mella C, Mikol V. "Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases." J. Mol. Biol.. 1998; 282(2): 359-68., PMID: 9735293  
DP00412 Walter S. "Structure and function of the GroE chaperone." Cell Mol Life Sci. 2002; 59(10): 1589-97., PMID: 12475168  
  Shewmaker F, Kerner MJ, Hayer-Hartl M, Klein G, Georgopoulos C, Landry SJ. "A mobile loop order-disorder transition modulates the speed of chaperonin cycling." Protein Sci. 2004; 13(8): 2139-48., PMID: 15238634 landry@tulane.edu
 Region 1Landry SJ, Taher A, Georgopoulos C, van der Vies SM. "Interplay of structure and disorder in cochaperonin mobile loops." Proc Natl Acad Sci U S A. 1996; 93(21): 11622-7., PMID: 8876186  
 Region 1Csizmók V, Szollosi E, Friedrich P, Tompa P. "A novel two-dimensional electrophoresis technique for the identification of intrinsically unstructured proteins." Mol Cell Proteomics. 2006; 5(2): 265-73., PMID: 16223749  
 Region 1Shewmaker F, Kerner MJ, Hayer-Hartl M, Klein G, Georgopoulos C, Landry SJ. "A mobile loop order-disorder transition modulates the speed of chaperonin cycling." Protein Sci. 2004; 13(8): 2139-48., PMID: 15238634 landry@tulane.edu
DP00414 Perederina A, Svetlov V, Vassylyeva MN, Tahirov TH, Yokoyama S, Artsimovitch I, Vassylyev DG. "Regulation through the secondary channel--structural framework for ppGpp-DksA synergism during transcription." Cell. 2004; 118(3): 297-309., PMID: 15294156  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10Perederina A, Svetlov V, Vassylyeva MN, Tahirov TH, Yokoyama S, Artsimovitch I, Vassylyev DG. "Regulation through the secondary channel--structural framework for ppGpp-DksA synergism during transcription." Cell. 2004; 118(3): 297-309., PMID: 15294156  
DP00415 Choi-Rhee E, Cronan JE. "The biotin carboxylase-biotin carboxyl carrier protein complex of Escherichia coli acetyl-CoA carboxylase." J Biol Chem. 2003; 278(33): 30806-12., PMID: 12794081  
 Region 1Cronan JE Jr. "Interchangeable enzyme modules. Functional replacement of the essential linker of the biotinylated subunit of acetyl-CoA carboxylase with a linker from the lipoylated subunit of pyruvate dehydrogenase." J Biol Chem. 2002; 277(25): 22520-7., PMID: 11956202  
DP00416 Roujeinikova A, Baldock C, Simon WJ, Gilroy J, Baker PJ, Stuitje AR, Rice DW, Slabas AR, Rafferty JB. "X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site." Structure. 2002; 10(6): 825-35., PMID: 12057197  
  Kim Y, Prestegard JH. "Refinement of the NMR structures for acyl carrier protein with scalar coupling data." Proteins. 1990; 8(4): 377-85., PMID: 2091027  
 Region 1, Region 2, Region 3, Region 4, Region 5Roujeinikova A, Baldock C, Simon WJ, Gilroy J, Baker PJ, Stuitje AR, Rice DW, Slabas AR, Rafferty JB. "X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site." Structure. 2002; 10(6): 825-35., PMID: 12057197  
DP00418 de La Coste A, Freitas AA. "Notch signaling: distinct ligands induce specific signals during lymphocyte development and maturation." Immunol Lett. 2006; 102(1): 1-9., PMID: 16140393  
 Region 1Popovic M, Coglievina M, Guarnaccia C, Verdone G, Esposito G, Pintar A, Pongor S. "Gene synthesis, expression, purification, and characterization of human Jagged-1 intracellular region." Protein Expr Purif. 2006; 47(2): 398-404., PMID: 16427310 pongor@icgeb.org
DP00419Region 4, Region 5, Region 6Wild K, Bohner T, Folkers G, Schulz GE. "The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue." Protein Sci. 1997; 6(10): 2097-106., PMID: 9336833  
 Region 1, Region 2, Region 3Wild K, Bohner T, Aubry A, Folkers G, Schulz GE. "The three-dimensional structure of thymidine kinase from herpes simplex virus type 1." FEBS Lett. 1995; 368(2): 289-92., PMID: 7628623  
DP00420 Copeland PR, Stepanik VA, Driscoll DM. "Insight into mammalian selenocysteine insertion: domain structure and ribosome binding properties of sec insertion sequence binding protein 2." Mol Cell Biol. 2001; 21(5): 1491-8., PMID: 11238886  
  Olieric V, Wolff P, Takeuchi A, Bec G, Birck C, Vitorino M, Kieffer B, Beniaminov A, Cavigiolio G, Theil E, Allmang C, Krol A, Dumas P. "SECIS-binding protein 2, a key player in selenoprotein synthesis, is an intrinsically disordered protein." Biochimie. 2009; 91(8): 1003-9., PMID: 19467292  
 Region 1Oliéric V, Wolff P, Takeuchi A, Bec G, Birck C, Vitorino M, Kieffer B, Beniaminov A, Cavigiolio G, Theil E, Allmang C, Krol A, Dumas P. "SECIS-binding protein 2, a key player in selenoprotein synthesis, is an intrinsically disordered protein." Biochimie. 2009; 91(8): 1003-9., PMID: 19467292  
 Region 1, Region 2Copeland PR, Stepanik VA, Driscoll DM. "Insight into mammalian selenocysteine insertion: domain structure and ribosome binding properties of sec insertion sequence binding protein 2." Mol Cell Biol. 2001; 21(5): 1491-8., PMID: 11238886  
DP00421 Svenningsson P, Nishi A, Fisone G, Girault JA, Nairn AC, Greengard P. "DARPP-32: an integrator of neurotransmission." Annu Rev Pharmacol Toxicol. 2004; 44: 269-96., PMID: 14744247  
 Region 1Hemmings HC Jr, Nairn AC, Aswad DW, Greengard P. "DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus." J Neurosci. 1984; 4(1): 99-110., PMID: 6319628  
DP00422 Travers A, Schneider R, Muskhelishvili G. "DNA supercoiling and transcription in Escherichia coli: The FIS connection." Biochimie. 2001; 83(2): 213-7., PMID: 11278071  
 Region 1Kostrewa D, Granzin J, Stock D, Choe HW, Labahn J, Saenger W. "Crystal structure of the factor for inversion stimulation FIS at 2.0 A resolution." J Mol Biol. 1992; 226(1): 209-26., PMID: 1619650  
 Region 1Yuan HS, Finkel SE, Feng JA, Kaczor-Grzeskowiak M, Johnson RC, Dickerson RE. "The molecular structure of wild-type and a mutant Fis protein: relationship between mutational changes and recombinational enhancer function or DNA binding." Proc Natl Acad Sci U S A. 1991; 88(21): 9558-62., PMID: 1946369 hanna@sinica.edu.tw
 Region 1Cheng YS, Yang WZ, Johnson RC, Yuan HS. "Structural analysis of the transcriptional activation on Fis: crystal structures of six Fis mutants with different activation properties." J Mol Biol. 2000; 302(5): 1139-51., PMID: 11183780 hanna@sinica.edu.tw
 Region 1Safo MK, Yang WZ, Corselli L, Cramton SE, Yuan HS, Johnson RC. "The transactivation region of the fis protein that controls site-specific DNA inversion contains extended mobile beta-hairpin arms." Embo J. 1997; 16(22): 6860-73., PMID: 9362499  
DP00423 Downs JA, Kosmidou E, Morgan A, Jackson SP. "Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone." Mol Cell. 2003; 6(11): 1685-92., PMID: 12820979  
 Region 1Ono K, Kusano O, Shimotakahara S, Shimizu M, Yamazaki T, Shindo H. "The linker histone homolog Hho1p from Saccharomyces cerevisiae represents a winged helix-turn-helix fold as determined by NMR spectroscopy." Nucleic Acids Res. 2003; 31(24): 7199-207., PMID: 14654695  
 Region 1Ali T, Coles P, Stevens TJ, Stott K, Thomas JO. "Two homologous domains of similar structure but different stability in the yeast linker histone, Hho1p." J Mol Biol. 2004; 338(1): 139-48., PMID: 15050829  
 Region 1Sanderson A, Stott K, Stevens TJ, Thomas JO. "Engineering the structural stability and functional properties of the GI domain into the intrinsically unfolded GII domain of the yeast linker histone Hho1p." J Mol Biol. 2005; 349(3): 608-20., PMID: 15878177  
DP00424 Hakata Y, Yamada M, Mabuchi N, Shida H. "The carboxy-terminal region of the human immunodeficiency virus type 1 protein Rev has multiple roles in mediating CRM1-related Rev functions." J Virol. 2002; 76(16): 8079-89., PMID: 12134013  
 Region 1Auer M, Gremlich HU, Seifert JM, Daly TJ, Parslow TG, Casari G, Gstach H. "Helix-loop-helix motif in HIV-1 Rev." Biochemistry. 1994; 33(10): 2988-96., PMID: 7510518  
 Region 1Daly TJ, Rusche JR, Maione TE, Frankel AD. "Circular dichroism studies of the HIV-1 Rev protein and its specific RNA binding site." Biochemistry. 1990; 29(42): 9791-5., PMID: 2125482  
DP00427Region 1, Region 2, Region 3Arjunan P, Nemeria N, Brunskill A, Chandrasekhar K, Sax M, Yan Y, Jordan F, Guest JR, Furey W. "Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A resolution." Biochemistry. 2002; 41(16): 5213-21., PMID: 11955070  
DP00428Region 1, Region 2, Region 3Cheng KY, Lowe ED, Sinclair J, Nigg EA, Johnson LN. "The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex." EMBO J. 2003; 22(21): 5757-68., PMID: 14592974  
DP00429Region 1Korndorfer IP, Fessner WD, Matthews BW. "The structure of rhamnose isomerase from Escherichia coli and its relation with xylose isomerase illustrates a change between inter and intra-subunit complementation during evolution." J Mol Biol. 2000; 300(4): 917-33., PMID: 10891278  
DP00430 Lolis E, Alber T, Davenport RC, Rose D, Hartman FC, Petsko GA. "Structure of yeast triosephosphate isomerase at 1.9-A resolution." Biochemistry. 1990; 29(28): 6609-18., PMID: 2204417  
 Region 1Brown FK, Kollman PA. "Molecular dynamics simulations of "loop closing" in the enzyme triose phosphate isomerase." J Mol Biol. 1987; 198(3): 533-46., PMID: 3430618  
 Region 1Joseph D, Petsko GA, Karplus M. "Anatomy of a conformational change: hinged "lid" motion of the triosephosphate isomerase loop." Science. 1990; 249(4975): 1425-8., PMID: 2402636  
DP00432Region 1, Region 2Allain FH, Yen YM, Masse JE, Schultze P, Dieckmann T, Johnson RC, Feigon J. "Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non-sequence-specific binding." EMBO J. 1999; 18(9): 2563-79., PMID: 10228169  
DP00433 Farabaugh PJ. "Sequence of the lacI gene." Nature. 1978; 274(5673): 765-9., PMID: 355891  
 Region 6Lewis M, Chang G, Horton NC, Kercher MA, Pace HC, Schumacher MA, Brennan RG, Lu P. "Crystal structure of the lactose operon repressor and its complexes with DNA and inducer." Science. 1996; 271(5253): 1247-54., PMID: 8638105  
 Region 1, Region 2, Region 3Slijper M, Bonvin AM, Boelens R, Kaptein R. "Refined structure of lac repressor headpiece (1-56) determined by relaxation matrix calculations from 2D and 3D NOE data: change of tertiary structure upon binding to the lac operator." J Mol Biol. 1996; 259(4): 761-73., PMID: 8683581  
 Region 4, Region 5Kercher MA, Lu P, Lewis M. "Lac repressor-operator complex." Curr Opin Struct Biol. 1997; 7(1): 76-85., PMID: 9032054  
DP00434Region 1Song J, Tyler RC, Wrobel RL, Frederick RO, Vojtek FC, Jeon WB, Lee MS, Markley JL. "Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein." Protein Sci. 2005; 14(4): 1059-63., PMID: 15741346  
DP00435 Egerton M, Ashe OR, Chen D, Druker BJ, Burgess WH, Samelson LE. "VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation." EMBO J. 1992; 11(10): 3533-40., PMID: 1382975  
  Watts GD, Wymer J, Kovach MJ, Mehta SG, Mumm S, Darvish D, Pestronk A, Whyte MP, Kimonis VE. "Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein." Nat Genet. 2004; 36(4): 377-81., PMID: 15034582  
  Zhang X, Shaw A, Bates PA, Newman RH, Gowen B, Orlova E, Gorman MA, Kondo H, Dokurno P, Lally J, Leonard G, Meyer H, van Heel M, Freemont PS. "Structure of the AAA ATPase p97." Mol Cell. 2000; 6(6): 1473-84., PMID: 11163219  
 Region 1, Region 2DeLaBarre B, Brunger AT. "Nucleotide dependent motion and mechanism of action of p97/VCP." J Mol Biol. 2005; 347(2): 437-52., PMID: 15740751 brunger@stanford.edu
DP00436 Ng JD, Ko TP, McPherson A. "Cloning, expression, and crystallization of jack bean (Canavalia ensiformis) canavalin." Plant Physiol. 1993; 101(3): 713-28., PMID: 8310055  
 Region 1, Region 2, Region 3, Region 4Ko TP, Ng JD, McPherson A. "The three-dimensional structure of canavalin from jack bean (Canavalia ensiformis)." Plant Physiol. 1993; 101(3): 729-44., PMID: 8310056  
DP00437 Park MS. "Expression of human RAD52 confers resistance to ionizing radiation in mammalian cells." J Biol Chem. 1995; 270(26): 15467-70., PMID: 7797537  
 Region 1Singleton MR, Wentzell LM, Liu Y, West SC, Wigley DB. "Structure of the single-strand annealing domain of human RAD52 protein." Proc Natl Acad Sci U S A. 2002; 99(21): 13492-7., PMID: 12370410  
DP00438Region 1Konrat R, Krautler B, Weiskirchen R, Bister K. "Structure of cysteine- and glycine-rich protein CRP2. Backbone dynamics reveal motional freedom and independent spatial orientation of the lim domains." J Biol Chem. 1998; 273(36): 23233-40., PMID: 9722554  
DP00441 Batra-Safferling R, Abarca Heidemann K, Korschen HG, Tziatzios C, Stoldt M, Budyak I, Willbold D, Schwalbe H, Klein-Seetharaman J, Kaupp UB. "Glutamic acid-rich proteins of rod photoreceptors are natively unfolded." J Biol Chem. 2006; 281(3): 1449-60., PMID: 16280326  
 Region 1Batra-Safferling R, Abarca Heidemann K, Korschen HG, Tziatzios C, Stoldt M, Budyak I, Willbold D, Schwalbe H, Klein-Seetharaman J, Kaupp UB. "Glutamic acid-rich proteins of rod photoreceptors are natively unfolded." J Biol Chem. 2006; 281(3): 1449-60., PMID: 16280326  
DP00443 Ozgenc A, Loeb LA. "Current advances in unraveling the function of the Werner syndrome protein." Mutat Res. 2005; 577((1-2)): 237-51., PMID: 15946710  
 Region 1Hu JS, Feng H, Zeng W, Lin GX, Xi XG. "Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein." Proc Natl Acad Sci U S A. 2005; 102(51): 18379–18384., PMID: 16339893  
DP00444 Augusteyn RC. "alpha-crystallin: a review of its structure and function." Clin Exp Optom. 2004; 87(6): 356-66., PMID: 15575808  
 Region 1Pasta SY, Raman B, Ramakrishna T, Rao ChM. "Role of the C-terminal extensions of alpha-crystallins. Swapping the C-terminal extension of alpha-crystallin to alphaB-crystallin results in enhanced chaperone activity." J Biol Chem. 2002; 277(48): 45821-8., PMID: 12235146  
 Region 1Carver JA, Lindner RA. "NMR spectroscopy of alpha-crystallin. Insights into the structure, interactions and chaperone action of small heat-shock proteins." Int J Biol Macromol. 1998; 22(3-4): 197-209., PMID: 9650074  
DP00445 Augusteyn RC. "alpha-crystallin: a review of its structure and function." Clin Exp Optom. 2004; 87(6): 356-66., PMID: 15575808  
 Region 1Pasta SY, Raman B, Ramakrishna T, Rao ChM. "Role of the C-terminal extensions of alpha-crystallins. Swapping the C-terminal extension of alpha-crystallin to alphaB-crystallin results in enhanced chaperone activity." J Biol Chem. 2002; 277(48): 45821-8., PMID: 12235146  
 Region 1Carver JA, Lindner RA. "NMR spectroscopy of alpha-crystallin. Insights into the structure, interactions and chaperone action of small heat-shock proteins." Int J Biol Macromol. 1998; 22(3-4): 197-209., PMID: 9650074  
DP00446 Larsen L, Ropke C. "Suppressors of cytokine signalling: SOCS." APMIS. 2002; 110(12): 833-44., PMID: 12645661  
 Region 1Babon JJ, Yao S, DeSouza DP, Harrison CF, Fabri LJ, Liepinsh E, Scrofani SD, Baca M, Norton RS. "Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain." FEBS J. 2005; 272(23): 6120-30., PMID: 16302975  
DP00447Region 1, Region 2Llorente MT, Garcia-Barreno B, Calero M, Camafeita E, Lopez JA, Longhi S, Ferron F, Varela PF, Melero JA. "Structural analysis of the human respiratory syncytial virus phosphoprotein: characterization of an {alpha}-helical domain involved in oligomerization." J Gen Virol. 2006; 87(Pt 1): 159-69., PMID: 16361428  
DP00448 Westendorf JJ, Koka S. "Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics." J Cell Biochem. 2004; 92(1): 29-41., PMID: 15095401  
 Region 1Schonichen A, Alexander M, Gasteier JE, Cuesta FE, Fackler OT, Geyer M. "Biochemical characterization of the diaphanous auto-regulatory interaction in the Formin-homology protein FHOD1." J Biol Chem. 2006; 281(8): 5084-5093., PMID: 16361249  
DP00449 Shiraiwa N, Inohara N, Okada S, Yuzaki M, Shoji S, Ohta S. "An additional form of rat Bcl-x, Bcl-xbeta, generated by an unspliced RNA, promotes apoptosis in promyeloid cells." J Biol Chem. 1996; 271(22): 13258-65., PMID: 8662675  
 Region 1, Region 2Aritomi M, Kunishima N, Inohara N, Ishibashi Y, Ohta S, Morikawa K. "Crystal structure of rat Bcl-xL. Implications for the function of the Bcl-2 protein family." J Biol Chem. 1997; 272(44): 27886-92., PMID: 9346936  
DP00450 Berglund L, Rasmussen JT, Andersen MD, Rasmussen MS, Petersen TE. "Purification of the bovine xanthine oxidoreductase from milk fat globule membranes and cloning of complementary deoxyribonucleic acid." J Dairy Sci. 1996; 79(2): 198-204., PMID: 8708081  
 Region 1, Region 2, Region 3Enroth C, Eger BT, Okamoto K, Nishino T, Pai EF. "Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: structure-based mechanism of conversion." Proc Natl Acad Sci U S A. 2000; 97(20): 10723-8., PMID: 11005854  
DP00455 Thurieau C, Brosius J, Burne C, Jolles P, Keen JH, Mattaliano RJ, Chow EP, Ramachandran KL, Kirchhausen T. "Molecular cloning and complete amino acid sequence of AP50, an assembly protein associated with clathrin-coated vesicles." DNA. 1988; 7(10): 663-9., PMID: 3148444  
 Region 1, Region 2, Region 3, Region 4Collins BM, McCoy AJ, Kent HM, Evans PR, Owen DJ. "Molecular architecture and functional model of the endocytic AP2 complex." Cell. 2002; 109(4): 523-35., PMID: 12086608  
DP00457Region 1, Region 2, Region 3Suzuki M, Jeong SY, Karbowski M, Youle RJ, Tjandra N. "The solution structure of human mitochondria fission protein Fis1 reveals a novel TPR-like helix bundle." J Mol Biol. 2003; 334(3): 445-58., PMID: 14623186  
DP00458 Andres DA, Seabra MC, Brown MS, Armstrong SA, Smeland TE, Cremers FP, Goldstein JL. "cDNA cloning of component A of Rab geranylgeranyl transferase and demonstration of its role as a Rab escort protein." Cell. 1993; 73(6): 1091-9., PMID: 8513495  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Rak A, Reents R, Pylypenko O, Niculae A, Sidorovitch V, Thoma NH, Waldmann H, Schlichting I, Goody RS, Alexandrov K. "Crystallization and preliminary X-ray diffraction analysis of the Rab escort protein-1 in complex with Rab geranylgeranyltransferase." J Struct Biol. 2001; 136(2): 158-61., PMID: 11886217  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Pylypenko O, Rak A, Reents R, Niculae A, Sidorovitch V, Cioaca MD, Bessolitsyna E, Thoma NH, Waldmann H, Schlichting I, Goody RS, Alexandrov K. "Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase." Mol Cell. 2003; 11(2): 483-94., PMID: 12620235  
DP00459 Lancaster CA, Taylor-Harris PM, Self AJ, Brill S, van Erp HE, Hall A. "Characterization of rhoGAP. A GTPase-activating protein for rho-related small GTPases." J Biol Chem. 1994; 269(2): 1137-42., PMID: 8288572  
 Region 1Barrett T, Xiao B, Dodson EJ, Dodson G, Ludbrook SB, Nurmahomed K, Gamblin SJ, Musacchio A, Smerdon SJ, Eccleston JF. "The structure of the GTPase-activating domain from p50rhoGAP." Nature. 1997; 385(6615): 458-61., PMID: 9009196  
DP00460 Monreal AW, Zonana J, Ferguson B. "Identification of a new splice form of the EDA1 gene permits detection of nearly all X-linked hypohidrotic ectodermal dysplasia mutations." Am J Hum Genet. 1998; 63(2): 380-9., PMID: 9683615  
 Region 1Hymowitz SG, Compaan DM, Yan M, Wallweber HJ, Dixit VM, Starovasnik MA, de Vos AM. "The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity." Structure. 2003; 11(12): 1513-20., PMID: 14656435  
DP00460_A003 Hymowitz SG, Compaan DM, Yan M, Wallweber HJ, Dixit VM, Starovasnik MA, de Vos AM. "The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity." Structure. 2003; 11(12): 1513-20., PMID: 14656435  
 Region 1Hymowitz SG, Compaan DM, Yan M, Wallweber HJ, Dixit VM, Starovasnik MA, de Vos AM. "The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity." Structure. 2003; 11(12): 1513-20., PMID: 14656435  
DP00461Region 1Anderluh G, Gokce I, Lakey JH. "A natively unfolded toxin domain uses its receptor as a folding template." J Biol Chem. 2004; 279(21): 22002-9., PMID: 15004032 j.h.lakey@ncl.ac.uk
 Region 1Zakharov SD, Eroukova VY, Rokitskaya TI, Zhalnina MV, Sharma O, Loll PJ, Zgurskaya HI, Antonenko YN, Cramer WA. "Colicin occlusion of OmpF and TolC channels: outer membrane translocons for colicin import." Biophys J. 2004; 87(6): 3901-11., PMID: 15465872  
 Region 1Hecht O, Ridley H, Boetzel R, Lewin A, Cull N, Chalton DA, Lakey JH, Moore GR. "Self-recognition by an intrinsically disordered protein." FEBS Lett. 2008; 582(17): 2673-7., PMID: 18573254  
 Region 1Vetter IR, Parker MW, Tucker AD, Lakey JH, Pattus F, Tsernoglou D. "Crystal structure of a colicin N fragment suggests a model for toxicity." Structure. 1998; 6(7): 863-74., PMID: 9687368  
 Region 1Anderluh G, Hong Q, Boetzel R, MacDonald C, Moore GR, Virden R, Lakey JH. "Concerted folding and binding of a flexible colicin domain to its periplasmic receptor TolA." J Biol Chem. 2003; 278(24): 21860-8., PMID: 12679333  
 Region 1Gokce I, Raggett EM, Hong Q, Virden R, Cooper A, Lakey JH. "The TolA-recognition site of colicin N. ITC, SPR and stopped-flow fluorescence define a crucial 27-residue segment." J Mol Biol. 2000; 304(4): 621-32., PMID: 11099384  
 Region 1Raggett EM, Bainbridge G, Evans LJ, Cooper A, Lakey JH. "Discovery of critical Tol A-binding residues in the bactericidal toxin colicin N: a biophysical approach." Mol Microbiol. 1998; 28(6): 1335-43., PMID: 9680221  
DP00462Region 1, Region 2Kauppi B, Nielsen BB, Ramaswamy S, Larsen IK, Thelander M, Thelander L, Eklund H. "The three-dimensional structure of mammalian ribonucleotide reductase protein R2 reveals a more-accessible iron-radical site than Escherichia coli R2." J Mol Biol. 1996; 262(5): 706-20., PMID: 8876648  
 Region 2Lycksell PO, Ingemarson R, Davis R, Graslund A, Thelander L. "1H NMR studies of mouse ribonucleotide reductase: the R2 protein carboxyl-terminal tail, essential for subunit interaction, is highly flexible but becomes rigid in the presence of protein R1." Biochemistry. 1994; 33(10): 2838-42., PMID: 8130196  
 Region 1, Region 2Nielsen BB, Kauppi B, Thelander M, Thelander L, Larsen IK, Eklund H. "Crystallization and crystallographic investigations of the small subunit of mouse ribonucleotide reductase." FEBS Lett. 1995; 373(3): 310-2., PMID: 7589490  
DP00463 Kaupmann K, Huggel K, Heid J, Flor PJ, Bischoff S, Mickel SJ, McMaster G, Angst C, Bittiger H, Froestl W, Bettler B. "Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors." Nature. 1997; 386(6622): 239-46., PMID: 9069281  
 Region 1Blein S, Ginham R, Uhrin D, Smith BO, Soares DC, Veltel S, McIlhinney RA, White JH, Barlow PN. "Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded." J Biol Chem. 2004; 279(46): 48292-306., PMID: 15304491 Paul.Barlow@ed.ac.uk
DP00464 Hahn SA, Schutte M, Hoque AT, Moskaluk CA, da Costa LT, Rozenblum E, Weinstein CL, Fischer A, Yeo CJ, Hruban RH, Kern SE. "DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1." Science. 1996; 271(5247): 350-3., PMID: 8553070  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10Qin B, Lam SS, Lin K. "Crystal structure of a transcriptionally active Smad4 fragment." Structure. 1999; 7(12): 1493-503., PMID: 10647180  
DP00465Region 1Vamvaca K, Vogeli B, Kast P, Pervushin K, Hilvert D. "An enzymatic molten globule: efficient coupling of folding and catalysis." Proc Natl Acad Sci U S A. 2004; 101(35): 12860-4., PMID: 15322276 hilvert@org.chem.eth
z.ch
 Region 1MacBeath G, Kast P, Hilvert D. "Redesigning enzyme topology by directed evolution." Science. 1998; 279(5358): 1958-61., PMID: 9506949 hilvert@org.chem.eth
z.ch
DP00466Region 1, Region 2Zahn R, Liu A, Luhrs T, Riek R, von Schroetter C, Lopez Garcia F, Billeter M, Calzolai L, Wider G, Wuthrich K. "NMR solution structure of the human prion protein." Proc Natl Acad Sci U S A. 2000; 97(1): 145-50., PMID: 10618385  
DP00467 Hryniewicz-Jankowska A, Czogalla A, Bok E, Sikorsk AF. "Ankyrins, multifunctional proteins involved in many cellular pathways." Folia Histochem Cytobiol. 2002; 40(3): 239-49., PMID: 12219834  
 Region 1Abdi KM, Mohler PJ, Davis JQ, Bennett V. "Isoform specificity of ankyrin-B: A site in the divergent C-terminal domain is required for intramolecular association." J Biol Chem. 2006; 281(9): 5741-9., PMID: 16368689  
DP00468 Li Q, Verma IM. "NF-kappaB regulation in the immune system." Nat Rev Immunol. 2002; 2(10): 725-34., PMID: 12360211  
 Region 1, Region 2Leonchiks A, Liepinsh E, Barishev M, Sharipo A, Masucci MG, Otting G. "Random coil conformation of a Gly/Ala-rich insert in IkappaB alpha excludes structural stabilization as the mechanism for protection against proteasomal degradation." FEBS Lett. 1998; 440(3): 365-9., PMID: 9872404  
 Region 1, Region 2Jaffray E, Wood KM, Hay RT. "Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65." Mol Cell Biol. 1995; 15(4): 2166-72., PMID: 7891711  
DP00469Region 1Yoon MK, Shin J, Choi G, Choi BS. "Intrinsically unstructured N-terminal domain of bZIP transcription factor HY5." Proteins. 2006; 65(4): 856-66., PMID: 17001643  
DP00470 Lou X, Zhu J, Zhang Q, Zang R, Chen Y, Yu Z, Zhao Y. "Genetic control of the opaque-2 gene and background polygenes over some kernel traits in maize (Zea mays L.)." Genetica. 2005; 124(2-3): 291-300., PMID: 16134340  
 Region 1Moreau VH, da Silva AC, Siloto RM, Valente AP, Leite A, Almeida FC. "The bZIP region of the plant transcription factor opaque-2 forms stable homodimers in solution and retains its helical structure upon subunit dissociation." Biochemistry. 2004; 43(16): 4862-8., PMID: 15096055  
DP00471 Welsch JA, Rossi R, Comanducci M, Granoff DM. "Protective activity of monoclonal antibodies to genome-derived neisserial antigen 1870, a Neisseria meningitidis candidate vaccine." J Immunol. 2004; 172(9): 5606-15., PMID: 15100304  
 Region 1Cantini F, Savino S, Scarselli M, Masignani V, Pizza M, Romagnoli G, Swennen E, Veggi D, Banci L, Rappuoli R. "Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis." J Biol Chem. 2006; 281(11): 7220-7., PMID: 16407174  
DP00472 Purdue PE, Lazarow PB. "Peroxisome biogenesis." Annu Rev Cell Dev Biol. 2001; 17: 701-52., PMID: 11687502  
 Region 1Carvalho AF, Costa-Rodrigues J, Correia I, Costa Pessoa J, Faria TQ, Martins CL, Fransen M, Sa-Miranda C, Azevedo JE. "The N-terminal half of the peroxisomal cycling receptor Pex5p is a natively unfolded domain." J Mol Biol. 2006; 356(4): 864-75., PMID: 16403517 jazevedo@ibmc.up.pt
 Region 1Dodt G, Gould SJ. "Multiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: evidence that PTS1 protein import is mediated by a cycling receptor." J Cell Biol. 1996; 135(6 Pt 2): 1763-74., PMID: 8991089  
 Region 1Otera H, Setoguchi K, Hamasaki M, Kumashiro T, Shimizu N, Fujiki Y. "Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import." Mol Cell Biol. 2002; 22(6): 1639-55., PMID: 11865044  
DP00473 Partch CL, Sancar A. "Photochemistry and photobiology of cryptochrome blue-light photopigments: the search for a photocycle." Photochem Photobiol. 2005; 81(6): 1291-304., PMID: 16164372  
 Region 1Partch CL, Clarkson MW, Ozgur S, Lee AL, Sancar A. "Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor." Biochemistry. 2005; 44(10): 3795-805., PMID: 15751956  
DP00474 Partch CL, Sancar A. "Photochemistry and photobiology of cryptochrome blue-light photopigments: the search for a photocycle." Photochem Photobiol. 2005; 81(6): 1291-304., PMID: 16164372  
 Region 1Partch CL, Clarkson MW, Ozgur S, Lee AL, Sancar A. "Role of structural plasticity in signal transduction by the cryptochrome blue-light photoreceptor." Biochemistry. 2005; 44(10): 3795-805., PMID: 15751956  
DP00475 Henras A, Henry Y, Bousquet-Antonelli C, Noaillac-Depeyre J, Gelugne JP, Caizergues-Ferrer M. "Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs." Embo J. 1998; 17(23): 7078-90., PMID: 9843512  
 Region 1, Region 2, Region 3Khanna M, Wu H, Johansson C, Caizergues-Ferrer M, Feigon J. "Structural study of the H/ACA snoRNP components Nop10p and the 3' hairpin of U65 snoRNA." RNA. 2006; 12(1): 40-52., PMID: 16373493  
DP00482Region 1, Region 2Zhou CZ, de La Sierra-Gallay IL, Quevillon-Cheruel S, Collinet B, Minard P, Blondeau K, Henckes G, Aufrere R, Leulliot N, Graille M, Sorel I, Savarin P, de la Torre F, Poupon A, Janin J, van Tilbeurgh H. "Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate." J Biol Chem. 2003; 278(50): 50371-6., PMID: 14514667  
DP00483Region 1Resende CG, Outeiro TF, Sands L, Lindquist S, Tuite MF. "Prion protein gene polymorphisms in Saccharomyces cerevisiae." Mol Microbiol. 2003; 49(4): 1005-17., PMID: 12890024  
 Region 1Scheibel T, Lindquist SL. "The role of conformational flexibility in prion propagation and maintenance for Sup35p." Nat Struct Biol. 2001; 8(11): 958-62., PMID: 11685242  
DP00484 Tamura T, Tamura N, Cejka Z, Hegerl R, Lottspeich F, Baumeister W. "Tricorn protease--the core of a modular proteolytic system." Science. 1996; 274(5291): 1385-9., PMID: 8910281  
 Region 1, Region 2Brandstetter H, Kim JS, Groll M, Huber R. "Crystal structure of the tricorn protease reveals a protein disassembly line." Nature. 2001; 414(6862): 466-70., PMID: 11719810  
DP00485 Desterro JM, Rodriguez MS, Kemp GD, Hay RT. "Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1." J Biol Chem. 1999; 274(15): 10618-24., PMID: 10187858  
 Region 1, Region 2Lois LM, Lima CD. "Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1." Embo J. 2005; 24(3): 439-51., PMID: 15660128  
DP00486 Desterro JM, Rodriguez MS, Kemp GD, Hay RT. "Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1." J Biol Chem. 1999; 274(15): 10618-24., PMID: 10187858  
 Region 1, Region 2, Region 3, Region 4Lois LM, Lima CD. "Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1." Embo J. 2005; 24(3): 439-51., PMID: 15660128  
DP00487Region 1, Region 2, Region 3Voegtli WC, Ge J, Perlstein DL, Stubbe J, Rosenzweig AC. "Structure of the yeast ribonucleotide reductase Y2Y4 heterodimer." Proc Natl Acad Sci U S A. 2001; 98(18): 10073-8., PMID: 11526233  
DP00488Region 1, Region 2, Region 3, Region 4Voegtli WC, Ge J, Perlstein DL, Stubbe J, Rosenzweig AC. "Structure of the yeast ribonucleotide reductase Y2Y4 heterodimer." Proc Natl Acad Sci U S A. 2001; 98(18): 10073-8., PMID: 11526233  
DP00489 Day AA, McQuillan CI, Termine JD, Young MR. "Molecular cloning and sequence analysis of the cDNA for small proteoglycan II of bovine bone." Biochem J. 1987; 248(3): 801-5., PMID: 3435485  
 Region 1, Region 2Scott PG, McEwan PA, Dodd CM, Bergmann EM, Bishop PN, Bella J. "Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan." Proc Natl Acad Sci U S A. 2004; 101(44): 15633-8., PMID: 15501918  
DP00490 Kasus-Jacobi A, Perdereau D, Auzan C, Clauser E, Van Obberghen E, Mauvais-Jarvis F, Girard J, Burnol AF. "Identification of the rat adapter Grb14 as an inhibitor of insulin actions." J Biol Chem. 1998; 273(40): 26026-35., PMID: 9748281  
 Region 1Moncoq K, Broutin I, Larue V, Perdereau D, Cailliau K, Browaeys-Poly E, Burnol AF, Ducruix A. "The PIR domain of Grb14 is an intrinsically unstructured protein: implication in insulin signaling." FEBS Lett. 2003; 554(3): 240-6., PMID: 14623073 broutin@pharmacie.un
iv-paris5.fr
 Region 1Moncoq K, Broutin I, Craescu CT, Vachette P, Ducruix A, Durand D. "SAXS study of the PIR domain from the Grb14 molecular adaptor: a natively unfolded protein with a transient structure primer?" Biophys J. 2004; 87(6): 4056-64., PMID: 15465854  
DP00491_C002 Williamson RA, Henry MD, Daniels KJ, Hrstka RF, Lee JC, Sunada Y, Ibraghimov-Beskrovnaya O, Campbell KP. "Dystroglycan is essential for early embryonic development: disruption of Reichert's membrane in Dag1-null mice." Hum Mol Genet. 1997; 6(6): 831-41., PMID: 9175728  
 Region 1Boffi A, Bozzi M, Sciandra F, Woellner C, Bigotti MG, Ilari A, Brancaccio A. "Plasticity of secondary structure in the N-terminal region of beta-dystroglycan." Biochim Biophys Acta. 2001; 1546(1): 114-21., PMID: 11257514  
 Region 1Bozzi M, Bianchi M, Sciandra F, Paci M, Giardina B, Brancaccio A, Cicero DO. "Structural characterization by NMR of the natively unfolded extracellular domain of beta-dystroglycan: toward the identification of the binding epitope for alpha-dystroglycan." Biochemistry. 2003; 42(46): 13717-24., PMID: 14622018 a.brancaccio@uniserv
.ccr.rm.cnr.it
DP00492 Jenster G, van der Korput HA, Trapman J, Brinkmann AO. "Identification of two transcription activation units in the N-terminal domain of the human androgen receptor." J Biol Chem. 1995; 270(13): 7341-6., PMID: 7706276  
  Simental JA, Sar M, Lane MV, French FS, Wilson EM. "Transcriptional activation and nuclear targeting signals of the human androgen receptor." J Biol Chem. 1991; 266(1): 510-8., PMID: 1985913  
 Region 1, Region 2, Region 3Reid J, Kelly SM, Watt K, Price NC, McEwan IJ. "Conformational analysis of the androgen receptor amino-terminal domain involved in transactivation. Influence of structure-stabilizing solutes and protein-protein interactions." J Biol Chem. 2002; 277(22): 20079-86., PMID: 11896058 iain.mcewan@abdn.ac.
uk
 Region 1Kumar R, Betney R, Li J, Thompson EB, McEwan IJ. "Induced alpha-helix structure in AF1 of the androgen receptor upon binding transcription factor TFIIF." Biochemistry. 2004; 43(11): 3008-13., PMID: 15023052  
DP00499 Corda D, Colanzi A, Luini A. "The multiple activities of CtBP/BARS proteins: the Golgi view." Trends Cell Biol. 2006; 16(3): 167-73., PMID: 16483777  
 Region 1Nardini M, Svergun D, Konarev PV, Spano S, Fasano M, Bracco C, Pesce A, Donadini A, Cericola C, Secundo F, Luini A, Corda D, Bolognesi M. "The C-terminal domain of the transcriptional corepressor CtBP is intrinsically unstructured." Protein Sci. 2006; 15(5): 1042-50., PMID: 16597837  
DP00500 Dendouga N, Callebaut I, Tomavo S. "A novel DNA repair enzyme containing RNA recognition, G-patch and specific splicing factor 45-like motifs in the protozoan parasite Toxoplasma gondii." Eur J Biochem. 2002; 269(14): 3393-401., PMID: 12135477  
 Region 1Frenal K, Callebaut I, Wecker K, Prochnicka-Chalufour A, Dendouga N, Zinn-Justin S, Delepierre M, Tomavo S, Wolff N. "Structural and Functional Characterization of the TgDRE Multidomain Protein, a DNA Repair Enzyme from Toxoplasma gondii." Biochemistry. 2006; 45(15): 4867-4874., PMID: 16605254  
DP00501 Werten S, Moras D. "A global transcription cofactor bound to juxtaposed strands of unwound DNA." Nat Struct Mol Biol. 2006; 13(2): 181-2., PMID: 16415882  
 Region 1Jonker HR, Wechselberger RW, Boelens R, Kaptein R, Folkers GE. "The Intrinsically Unstructured Domain of PC4 Modulates the Activity of the Structured Core through Inter- and Intramolecular Interactions." Biochemistry. 2006; 45(15): 5067-81., PMID: 16605275  
DP00502 Ha HJ, Kubagawa H, Burrows PD. "Molecular cloning and expression pattern of a human gene homologous to the murine mb-1 gene." J Immunol. 1992; 148(5): 1526-31., PMID: 1538135  
 Region 1Sigalov A, Aivazian D, Stern L. "Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif." Biochemistry. 2004; 43(7): 2049-61., PMID: 14967045 Alexander.Sigalov@um
assmed.edu
DP00503 Hashimoto S, Gregersen PK, Chiorazzi N. "The human Ig-beta cDNA sequence, a homologue of murine B29, is identical in B cell and plasma cell lines producing all the human Ig isotypes." J Immunol. 1993; 150(2): 491-8., PMID: 8419481  
 Region 1Sigalov A, Aivazian D, Stern L. "Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif." Biochemistry. 2004; 43(7): 2049-61., PMID: 14967045 Alexander.Sigalov@um
assmed.edu
DP00504 Woychik NA, Liao SM, Kolodziej PA, Young RA. "Subunits shared by eukaryotic nuclear RNA polymerases." Genes Dev. 1990; 4(3): 313-23., PMID: 2186966  
 Region 1Kang X, Hu Y, Li Y, Guo X, Jiang X, Lai L, Xia B, Jin C. "Structural, biochemical and dynamic characterizations of the hRPB8 subunit of human RNA polymerases." J Biol Chem. 2006; 281(26): 18216-26., PMID: 16632472  
DP00505 Tunnacliffe A, Sims JE, Rabbitts TH. "T3 delta pre-mRNA is transcribed from a non-TATA promoter and is alternatively spliced in human T cells." Embo J. 1986; 5(6): 1245-52., PMID: 3488209  
 Region 1Sigalov A, Aivazian D, Stern L. "Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif." Biochemistry. 2004; 43(7): 2049-61., PMID: 14967045 Alexander.Sigalov@um
assmed.edu
DP00506 Clevers HC, Dunlap S, Wileman TE, Terhorst C. "Human CD3-epsilon gene contains three miniexons and is transcribed from a non-TATA promoter." Proc Natl Acad Sci U S A. 1988; 85(21): 8156-60., PMID: 3267235  
 Region 1Sigalov A, Aivazian D, Stern L. "Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif." Biochemistry. 2004; 43(7): 2049-61., PMID: 14967045 Alexander.Sigalov@um
assmed.edu
DP00508 Krissansen GW, Owen MJ, Verbi W, Crumpton MJ. "Primary structure of the T3 gamma subunit of the T3/T cell antigen receptor complex deduced from cDNA sequences: evolution of the T3 gamma and delta subunits." Embo J. 1986; 5(8): 1799-808., PMID: 2944745  
 Region 1Sigalov A, Aivazian D, Stern L. "Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif." Biochemistry. 2004; 43(7): 2049-61., PMID: 14967045 Alexander.Sigalov@um
assmed.edu
DP00509 Kuster H, Thompson H, Kinet JP. "Characterization and expression of the gene for the human Fc receptor gamma subunit. Definition of a new gene family." J Biol Chem. 1990; 265(11): 6448-52., PMID: 2138619  
 Region 1Sigalov A, Aivazian D, Stern L. "Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif." Biochemistry. 2004; 43(7): 2049-61., PMID: 14967045 Alexander.Sigalov@um
assmed.edu
DP00510 Vasseur S, Vidal Mallo G, Fiedler F, Bodeker H, Canepa E, Moreno S, Iovanna JL. "Cloning and expression of the human p8, a nuclear protein with mitogenic activity." Eur J Biochem. 1999; 259(3): 670-5., PMID: 10092851  
 Region 1Encinar JA, Mallo GV, Mizyrycki C, Giono L, Gonzalez-Ros JM, Rico M, Canepa E, Moreno S, Neira JL, Iovanna JL. "Human p8 is a HMG-I/Y-like protein with DNA binding activity enhanced by phosphorylation." J Biol Chem. 2001; 276(4): 2742-51., PMID: 11056169  
DP00511 Pennacchio LA, Lehesjoki AE, Stone NE, Willour VL, Virtaneva K, Miao J, D'Amato E, Ramirez L, Faham M, Koskiniemi M, Warrington JA, Norio R, de la Chapelle A, Cox DR, Myers RM. "Mutations in the gene encoding cystatin B in progressive myoclonus epilepsy (EPM1)." Science. 1996; 271(5256): 1731-4., PMID: 8596935  
  Riccio, M., Di Giaimo, R., Pianetti, S., Palmieri, P. P., Melli, M., Santi, S. "Nuclear localization of cystatin B, the cathepsin inhibitor implicated in myoclonus epilepsy (EPM1)." Exp Cell Res. 2001; 262(2): 84-94., PMID: 11139332  
  Zerovnik, E., Pompe-Novak, M., Skarabot, M., Ravnikar, M., Musevic, I., Turk, V. "Human stefin B readily forms amyloid fibrils in vitro." Biochim Biophys Acta. 2002; 1594(1): 1-5., PMID: 11825603  
 Region 1Rabzelj, S., Turk, V., Zerovnik, E. "In vitro study of stability and amyloid-fibril formation of two mutants of human stefin B (cystatin B) occurring in patients with EPM1." Protein Sci. 2005; 14(10): 2713-22., PMID: 16155205  
DP00512 Xing Y, Draper DE. "Stabilization of a ribosomal RNA tertiary structure by ribosomal protein L11." J Mol Biol. 1995; 249(2): 319-31., PMID: 7783196  
  Liljas A. "Comparative biochemistry and biophysics of ribosomal proteins." Int Rev Cytol. 1991; 124: 103-36., PMID: 2001915 mmarkus@wyeth.com
 Region 1Markus MA, Hinck AP, Huang S, Draper DE, Torchia DA. "High resolution solution structure of ribosomal protein L11-C76, a helical protein with a flexible loop that becomes structured upon binding to RNA." Nat Struct Biol. 1997; 4(1): 70-7., PMID: 8989327  
 Region 1Hinck AP, Markus MA, Huang S, Grzesiek S, Kustonovich I, Draper DE, Torchia DA. "The RNA binding domain of ribosomal protein L11: three-dimensional structure of the RNA-bound form of the protein and its interaction with 23 S rRNA." J Mol Biol. 1997; 274(1): 101-13., PMID: 9398519 mmarkus@wyeth.com
DP00513Region 1Corazza A, Rosano C, Pagano K, Alverdi V, Esposito G, Capanni C, Bemporad F, Plakoutsi G, Stefani M, Chiti F, Zuccotti S, Bolognesi M, Viglino P. "Structure, conformational stability, and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus." Proteins. 2006; 62(1): 64-79., PMID: 16287076 stefani@scibio.unifi
.it
 Region 1Plakoutsi G, Taddei N, Stefani M, Chiti F. "Aggregation of the Acylphosphatase from Sulfolobus solfataricus: the folded and partially unfolded states can both be precursors for amyloid formation." J Biol Chem. 2004; 279(14): 14111-9., PMID: 14724277 fchiti@scibio.unifi.
it
DP00514 Belrhali H, Yaremchuk A, Tukalo M, Larsen K, Berthet-Colominas C, Leberman R, Beijer B, Sproat B, Als-Nielsen J, Grübel G, et al. "Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate." Science. 1994; 263(5152): 1432-6., PMID: 8128224  
 Region 2, Region 3Cusack S, Yaremchuk A, Tukalo M. "The crystal structure of the ternary complex of T.thermophilus seryl-tRNA synthetase with tRNA(Ser) and a seryl-adenylate analogue reveals a conformational switch in the active site." EMBO J. 1996; 15(11): 2834-42., PMID: 8654381  
 Region 1, Region 2, Region 3, Region 4Biou V, Yaremchuk A, Tukalo M, Cusack S. "The 2.9 A crystal structure of T. thermophilus seryl-tRNA synthetase complexed with tRNA(Ser)." Science. 1994; 263(5152): 1404-10., PMID: 8128220  
 Region 1, Region 3, Region 5Fujinaga M, Berthet-Colominas C, Yaremchuk AD, Tukalo MA, Cusack S. "Refined crystal structure of the seryl-tRNA synthetase from Thermus thermophilus at 2.5 A resolution." J Mol Biol. 1993; 234(1): 222-33., PMID: 8230201  
DP00515 Petitpas I, Grüne T, Bhattacharya AA, Curry S. "Crystal structures of human serum albumin complexed with monounsaturated and polyunsaturated fatty acids." J Mol Biol. 2001; 314(5): 955-60., PMID: 11743713  
  Lawn RM, Adelman J, Bock SC, Franke AE, Houck CM, Najarian RC, Seeburg PH, Wion KL. "The sequence of human serum albumin cDNA and its expression in E. coli." Nucleic Acids Res. 1981; 9(22): 6103-114., PMID: 6171778  
 Region 1, Region 2Sugio S, Kashima A, Mochizuki S, Noda M, Kobayashi K. "Crystal structure of human serum albumin at 2.5 A resolution." Protein Eng. 1999; 12(6): 439-46., PMID: 10388840  
DP00516Region 1Ko TP, Chen YK, Robinson H, Tsai PC, Gao YG, Chen AP, Wang AH, Liang PH. "Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis." J Biol Chem. 2001; 276(50): 47474-82., PMID: 11581264  
DP00517 Agarkova I, Auerbach D, Ehler E, Perriard JC. "A novel marker for vertebrate embryonic heart, the EH-myomesin isoform." J Biol Chem. 2000; 275(14): 10256-64., PMID: 10744711  
 Region 1Schoenauer R, Bertoncini P, Machaidze G, Aebi U, Perriard JC, Hegner M, Agarkova I. "Myomesin is a molecular spring with adaptable elasticity." J Mol Biol. 2005; 349(2): 367-79., PMID: 15890201 irina.agarkova@cell.
biol.ethz.ch
DP00518 Shibue T, Taniguchi T. "BH3-only proteins: Integrated control point of apoptosis." Int J Cancer. 2006; 119(9): 2036-43., PMID: 16572413  
  Willis SN, Adams JM. "Life in the balance: how BH3-only proteins induce apoptosis." Curr Opin Cell Biol. 2005; 17(6): 617-25., PMID: 16243507  
  O'Connor L, Strasser A, O'Reilly LA, Hausmann G, Adams JM, Cory S, Huang DC. "Bim: a novel member of the Bcl-2 family that promotes apoptosis." Embo J. 1998; 17(2): 384-95., PMID: 9430630  
 Region 1Hinds MG, Smits C, Fredericks-Short R, Risk JM, Bailey M, Huang DC, Day CL. "Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets." Cell Death Differ. 2006., PMID: 16645638  
DP00519 Hanson CA, Miller JR. "Non-traditional roles for the Adenomatous Polyposis Coli (APC) tumor suppressor protein." Gene. 2005; 361: 1-12., PMID: 16185824  
 Region 1Liu J, Xing Y, Hinds TR, Zheng J, Xu W. "The Third 20 Amino Acid Repeat Is the Tightest Binding Site of APC for beta-Catenin." J Mol Biol. 2006; 360(1): 133-44., PMID: 16753179  
DP00520Region 1Hu T, Krezel AM, Li C, Coffey RJ. "Structural studies of human Naked2: a biologically active intrinsically unstructured protein." Biochem Biophys Res Commun. 2006; 350(4): 911-5., PMID: 17045239  
DP00521Region 1Sanchez-Puig N, Veprintsev DB, Fersht AR. "Human full-length Securin is a natively unfolded protein." Protein Sci. 2005; 14(6): 1410-8., PMID: 15929994  
DP00524 Rodriguez-Feo JA, Hellings WE, Verhoeven BA, Moll FL, de Kleijn DP, Prendergast J, Gao Y, van der Graaf Y, Tellides G, Sessa WC, Pasterkamp G. "Low levels of Nogo-B in human carotid atherosclerotic plaques are associated with an atheromatous phenotype, restenosis, and stenosis severity." Arterioscler Thromb Vasc Biol. 2007; 27(6): 1354-60., PMID: 17413036  
  Li M, Song J. "Nogo-B receptor possesses an intrinsically unstructured ectodomain and a partially folded cytoplasmic domain." Biochem Biophys Res Commun. 2007; 360(1): 128-34., PMID: 17585875  
 Region 1, Region 2Li M, Song J. "The N- and C-termini of the human Nogo molecules are intrinsically unstructured: bioinformatics, CD, NMR characterization, and functional implications." Proteins. 2007; 68(1): 100-8., PMID: 17397058  
DP00527 Prevete N, Rossi FW, Triggiani M, Marone G, de Paulis A, Metafora V, De Maria S, Carteni M, Ragone R, Ravagnan G, Metafora S. "Antiapoptotic Seminal Vesicle Protein IV Induces Histamine Release from Human FcepsilonRI+ Cells." Int Arch Allergy Immunol. 2009; 151(4): 318-330., PMID: 19851073  
  Mansson PE, Sugino A, Harris SE. "Use of a cloned double stranded cDNA coding for a major androgen dependent protein in rat seminal vesicle secretion: the effect of testosterone in gene expression." Nucleic Acids Res. 1981; 9: 935-946., PMID: 6164983  
  Pan YC, Silverberg AB, Harris SE, Li SS. "Complete amino acid sequence of a major secretory protein from rat seminal vesicle." Int J Pept Protein Res. 1980; 16: 143-146., PMID: 7007263  
 Region 1Vilasi S, Ragone R. "Abundance of intrinsic disorder in SV-IV, a multifunctional androgen-dependent protein secreted from rat seminal vesicle." FEBS J. 2008; 275(4): 763-764., PMID: 18215165  
 Region 1Metafora S, Esposito C, Caputo I, Lepretti M, Cassese D, Dicitore A, Ferranti P, Stiuso P. "Seminal vesicle protein IV and its derived active peptides: a possible physiological role in seminal clotting." Semin Thromb Hemost. 2007; 33(1): 53-9., PMID: 17253190  
 Region 1Caporale C, Caruso C, Colonna G, Facchiano A, Ferranti P, Mamone G, Picariello G, Colonna F, Metafora S, Stiuso P. "Structural properties of the protein SV-IV." Eur J Biochem. 2004; 271(2): 263-71., PMID: 14717694  
 Region 1Stiuso P, Metafora S, Facchiano AM, Colonna G, Ragone R. "The self-association of protein SV-IV and its possible functional implications." Eur J Biochem. 1999; 266(3): 1029-35., PMID: 10583398  
DP00529 Golovanov AP, Barillà D, Golovanova M, Hayes F, Lian LY. "ParG, a protein required for active partition of bacterial plasmids, has a dimeric ribbon-helix-helix structure." Mol Microbiol. 2003; 50(4): 1141-53., PMID: 14622405  
 Region 1Carmelo E, Barillà D, Golovanov AP, Lian LY, Derome A, Hayes F. "The unstructured N-terminal tail of ParG modulates assembly of a quaternary nucleoprotein complex in transcription repression." J Biol Chem. 2005; 280(31): 28683-91., PMID: 15951570  
DP00530 Koag MC, Fenton RD, Wilkens S, Close TJ. "The binding of maize DHN1 to lipid vesicles. Gain of structure and lipid specificity." Plant Physiol. 2003; 131(1): 309-16., PMID: 12529538  
 Region 1Koag MC, Fenton RD, Wilkens S, Close TJ. "The binding of maize DHN1 to lipid vesicles. Gain of structure and lipid specificity." Plant Physiol. 2003; 131(1): 309-16., PMID: 12529538  
DP00531 Goldgur Y, Rom S, Ghirlando R, Shkolnik D, Shadrin N, Konrad Z, Bar-Zvi D. "Desiccation and zinc binding induce transition of tomato abscisic acid stress ripening 1, a water stress- and salt stress-regulated plant-specific protein, from unfolded to folded state." Plant Physiol. 2007; 143(2): 617-28., PMID: 17189335  
 Region 1Goldgur Y, Rom S, Ghirlando R, Shkolnik D, Shadrin N, Konrad Z, Bar-Zvi D. "Desiccation and zinc binding induce transition of tomato abscisic acid stress ripening 1, a water stress- and salt stress-regulated plant-specific protein, from unfolded to folded state." Plant Physiol. 2007; 143(2): 617-28., PMID: 17189335  
DP00532 Carlberg I, Hansson M, Kieselbach T, Schröder WP, Andersson B, Vener AV. "A novel plant protein undergoing light-induced phosphorylation and release from the photosynthetic thylakoid membranes." Proc Natl Acad Sci U S A. 2003; 100(2): 757-62., PMID: 12524456  
 Region 1Song J, Lee MS, Carlberg I, Vener AV, Markley JL. "Micelle-Induced Folding of Spinach Thylakoid Soluble Phosphoprotein of 9 kDa and Its Functional Implications." Biochemistry. 2006; 45(51): 15633-15643., PMID: 17176085  
DP00533 McBryant SJ, Krause C, Woodcock CL, Hansen JC. "The silent information regulator 3 protein, SIR3p, binds to chromatin fibers and assembles a hypercondensed chromatin architecture in the presence of salt." Mol. Cell. Biol.. 2008; 28(11): 3563-72., PMID: 18362167  
  McBryant SJ, Krause C, Hansen JC. "Domain Organization and Quaternary Structure of the Saccharomyces cerevisiae Silent Information Regulator 3 Protein, Sir3p." Biochemistry. 2006; 45(51): 15941-8., PMID: 17176117  
  Adkins NL, McBryant SJ, Johnson CN, Leidy JM, Woodcock CL, Robert CH, Hansen JC, Georgel PT. "Role of nucleic acid binding in Sir3p-dependent interactions with chromatin fibers." Biochemistry. 2009; 48(2): 276-88., PMID: 19099415  
 Region 1Connelly JJ, Yuan P, Hsu HC, Li Z, Xu RM, Sternglanz R. "Structure and function of the Saccharomyces cerevisiae Sir3 BAH domain." Mol. Cell. Biol.. 2006; 26(8): 3256-65., PMID: 16581798  
 Region 1, Region 2, Region 3McBryant SJ, Krause C, Hansen JC. "Domain Organization and Quaternary Structure of the Saccharomyces cerevisiae Silent Information Regulator 3 Protein, Sir3p." Biochemistry. 2006; 45(51): 15941-8., PMID: 17176117  
 Region 3Ehrentraut S, Hassler M, Oppikofer M, Kueng S, Weber JM, Mueller JW, Gasser SM, Ladurner AG, Ehrenhofer-Murray AE. "Structural basis for the role of the Sir3 AAA+ domain in silencing: interaction with Sir4 and unmethylated histone H3K79." Genes Dev.. 2011; 25(17): 1835-46., PMID: 21896656  
 Region 1Armache KJ, Garlick JD, Canzio D, Narlikar GJ, Kingston RE. "Structural basis of silencing: Sir3 BAH domain in complex with a nucleosome at 3.0 Å resolution." Science. 2011; 334(6058): 977-82., PMID: 22096199  
 Region 1Hou Z, Danzer JR, Fox CA, Keck JL. "Structure of the Sir3 protein bromo adjacent homology (BAH) domain from S. cerevisiae at 1.95 A resolution." Protein Sci.. 2006; 15(5): 1182-6., PMID: 16641491  
 Region 2Chen Y, Rai R, Zhou ZR, Kanoh J, Ribeyre C, Yang Y, Zheng H, Damay P, Wang F, Tsujii H, Hiraoka Y, Shore D, Hu HY, Chang S, Lei M. "A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms." Nat. Struct. Mol. Biol.. 2011; 18(2): 213-21., PMID: 21217703  
DP00534 Marri L, Trost P, Trivelli X, Gonnelli L, Pupillo P, Sparla F. "Spontaneous assembly of photosynthetic supramolecular complexes as mediated by the intrinsically unstructured protein CP12." J Biol Chem. 2007., PMID: 17947231  
  Olinares PD, Ponnala L, van Wijk KJ. "Megadalton complexes in the chloroplast stroma of Arabidopsis thaliana characterized by size exclusion chromatography, mass spectrometry, and hierarchical clustering." Mol. Cell Proteomics. 2010; 9(7): 1594-615., PMID: 20423899  
  Marri L, Pesaresi A, Valerio C, Lamba D, Pupillo P, Trost P, Sparla F. "In vitro characterization of Arabidopsis CP12 isoforms reveals common biochemical and molecular properties." J. Plant Physiol.. 2010; 167(12): 939-50., PMID: 20399532  
  Kleffmann T, Russenberger D, von Zychlinski A, Christopher W, Sjölander K, Gruissem W, Baginsky S. "The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions." Curr. Biol.. 2004; 14(5): 354-62., PMID: 15028209  
  Singh P, Kaloudas D, Raines CA. "Expression analysis of the Arabidopsis CP12 gene family suggests novel roles for these proteins in roots and floral tissues." J. Exp. Bot.. 2008; 59(14): 3975-85., PMID: 18974062  
  Zybailov B, Rutschow H, Friso G, Rudella A, Emanuelsson O, Sun Q, van Wijk KJ. "Sorting signals, N-terminal modifications and abundance of the chloroplast proteome." PLoS One. 2008; 3(4): e1994., PMID: 18431481  
  Fermani S, Trivelli X, Sparla F, Thumiger A, Calvaresi M, Marri L, Falini G, Zerbetto F, Trost P. "Conformational selection and folding-upon-binding of intrinsically disordered protein CP12 regulate photosynthetic enzymes assembly." J. Biol. Chem.. 2012; 287(25): 21372-83., PMID: 22514274  
  Marri L, Trost P, Pupillo P, Sparla F. "Reconstitution and properties of the recombinant glyceraldehyde-3-phosphate dehydrogenase/CP12/phosphoribulokinase supramolecular complex of Arabidopsis." Plant Physiol.. 2005; 139(3): 1433-43., PMID: 16258009  
  Marri L, Sparla F, Pupillo P, Trost P. "Co-ordinated gene expression of photosynthetic glyceraldehyde-3-phosphate dehydrogenase, phosphoribulokinase, and CP12 in Arabidopsis thaliana." J. Exp. Bot.. 2004; 56(409): 73-80., PMID: 15533878  
 Region 1Marri L, Trost P, Trivelli X, Gonnelli L, Pupillo P, Sparla F. "Spontaneous assembly of photosynthetic supramolecular complexes as mediated by the intrinsically unstructured protein CP12." J Biol Chem. 2007., PMID: 17947231  
 Region 2, Region 3Fermani S, Trivelli X, Sparla F, Thumiger A, Calvaresi M, Marri L, Falini G, Zerbetto F, Trost P. "Conformational selection and folding-upon-binding of intrinsically disordered protein CP12 regulate photosynthetic enzymes assembly." J. Biol. Chem.. 2012; 287(25): 21372-83., PMID: 22514274  
 Region 1Marri L, Trost P, Pupillo P, Sparla F. "Reconstitution and properties of the recombinant glyceraldehyde-3-phosphate dehydrogenase/CP12/phosphoribulokinase supramolecular complex of Arabidopsis." Plant Physiol.. 2005; 139(3): 1433-43., PMID: 16258009  
DP00535 Khaymina SS, Kenney JM, Schroeter MM, Chalovich JM. "Fesselin is a natively unfolded protein." J Proteome Res. 2007; 6(9): 3648-54., PMID: 17676886  
 Region 1Khaymina SS, Kenney JM, Schroeter MM, Chalovich JM. "Fesselin is a natively unfolded protein." J Proteome Res. 2007; 6(9): 3648-54., PMID: 17676886  
DP00536Region 1Thalhammer A, Hundertmark M, Popova AV, Seckler R, Hincha DK. "Interaction of two intrinsically disordered plant stress proteins (COR15A and COR15B) with lipid membranes in the dry state." Biochim. Biophys. Acta. 2010; 1798(9): 1812-20., PMID: 20510170  
DP00537 Garcia W, de Araújo AP, Neto Mde O, Ballestero MR, Polikarpov I, Tanaka M, Tanaka T, Garratt RC. "Dissection of a human septin: definition and characterization of distinct domains within human SEPT4." Biochemistry. 2006; 45(46): 13918-31., PMID: 17105210  
 Region 1Garcia W, de Araújo AP, Neto Mde O, Ballestero MR, Polikarpov I, Tanaka M, Tanaka T, Garratt RC. "Dissection of a human septin: definition and characterization of distinct domains within human SEPT4." Biochemistry. 2006; 45(46): 13918-31., PMID: 17105210  
DP00538 Seo MD, Park SJ, Kim HJ, Lee BJ. "Identification of the WW domain-interaction sites in the unstructured N-terminal domain of EBV LMP 2A." FEBS Lett. 2007; 581(1): 65-70., PMID: 17174309  
 Region 1Seo MD, Park SJ, Kim HJ, Lee BJ. "Identification of the WW domain-interaction sites in the unstructured N-terminal domain of EBV LMP 2A." FEBS Lett. 2007; 581(1): 65-70., PMID: 17174309  
DP00539 Adams VH, McBryant SJ, Wade PA, Woodcock CL, Hansen JC. "Intrinsic disorder and autonomous domain function in the multifunctional nuclear protein, MeCP2." J Biol Chem. 2007; 282(20): 15057-64., PMID: 17371874  
  Ghosh RP, Nikitina T, Horowitz-Scherer RA, Gierasch LM, Uversky VN, Hite K, Hansen JC, Woodcock CL. "Unique physical properties and interactions of the domains of methylated DNA binding protein 2." Biochemistry. 2010; 49(20): 4395-410., PMID: 20405910  
 Region 1, Region 2, Region 3, Region 4, Region 5Adams VH, McBryant SJ, Wade PA, Woodcock CL, Hansen JC. "Intrinsic disorder and autonomous domain function in the multifunctional nuclear protein, MeCP2." J Biol Chem. 2007; 282(20): 15057-64., PMID: 17371874  
 Region 5, Region 6, Region 7, Region 8, Region 9, Region 10Ghosh RP, Nikitina T, Horowitz-Scherer RA, Gierasch LM, Uversky VN, Hite K, Hansen JC, Woodcock CL. "Unique physical properties and interactions of the domains of methylated DNA binding protein 2." Biochemistry. 2010; 49(20): 4395-410., PMID: 20405910  
DP00540 Yiu CP, Beavil RL, Chan HY. "Biophysical characterisation reveals structural disorder in the nucleolar protein, Dribble." Biochem Biophys Res Commun. 2006; 343(1): 311-8., PMID: 16542639  
 Region 1Yiu CP, Beavil RL, Chan HY. "Biophysical characterisation reveals structural disorder in the nucleolar protein, Dribble." Biochem Biophys Res Commun. 2006; 343(1): 311-8., PMID: 16542639  
DP00541 Geething NC, Spudich JA. "Identification of a minimal myosin Va binding site within an intrinsically unstructured domain of melanophilin." J Biol Chem. 2007; 282(29): 21518-28., PMID: 17513864  
 Region 1Geething NC, Spudich JA. "Identification of a minimal myosin Va binding site within an intrinsically unstructured domain of melanophilin." J Biol Chem. 2007; 282(29): 21518-28., PMID: 17513864  
DP00543 Voronova A, Meyer-Klaucke W, Meyer T, Rompel A, Krebs B, Kazantseva J, Sillard R, Palumaa P. "Oxidative switches in functioning of mammalian copper chaperone Cox17." Biochem J. 2007; 408(1): 139-48., PMID: 17672825  
 Region 1Banci L, Bertini I, Ciofi-Baffoni S, Janicka A, Martinelli M, Kozlowski H, Palumaa P. "A structural-dynamical characterization of human Cox17." J Biol Chem. 2008; 283(12): 7912-20., PMID: 18093982  
DP00544 Kim H, Lee SH, Han JH, Lee JA, Cheang YH, Chang DJ, Lee YS, Kaang BK. "A nucleolar protein ApLLP induces ApC/EBP expression required for long-term synaptic facilitation in aplysia neurons." Neuron. 2006; 49(5): 707-18., PMID: 16504946  
 Region 1Liu J, Song J. "A novel nucleolar transcriptional activator ApLLP for long-term memory formation is intrinsically unstructured but functionally active." Biochem Biophys Res Commun. 2008; 366(2): 585-91., PMID: 18078811  
DP00546 Raychaudhuri S, Majumder P, Sarkar S, Giri K, Mukhopadhyay D, Bhattacharyya NP. "Huntingtin interacting protein HYPK is intrinsically unstructured." Proteins. 2008; 71(4): 1686-98., PMID: 18076027  
 Region 1Raychaudhuri S, Majumder P, Sarkar S, Giri K, Mukhopadhyay D, Bhattacharyya NP. "Huntingtin interacting protein HYPK is intrinsically unstructured." Proteins. 2008; 71(4): 1686-98., PMID: 18076027  
DP00549 Hayes PL, Lytle BL, Volkman BF, Peterson FC. "The solution structure of ZNF593 from Homo sapiens reveals a zinc finger in a predominately unstructured protein." Protein Sci. 2008; 17(3): 571-6., PMID: 18287285  
 Region 1, Region 2, Region 3Hayes PL, Lytle BL, Volkman BF, Peterson FC. "The solution structure of ZNF593 from Homo sapiens reveals a zinc finger in a predominately unstructured protein." Protein Sci. 2008; 17(3): 571-6., PMID: 18287285  
DP00550Region 1Permyakov SE, Bakunts AG, Denesyuk AI, Knyazeva EL, Uversky VN, Permyakov EA. "Apo-parvalbumin as an intrinsically disordered protein." Proteins. 2008., PMID: 18260106  
DP00551Region 1Crimmins DL, Kao JL. "The human cardiac hormone fragment N-terminal pro B-type natriuretic peptide is an intrinsically unstructured protein." Arch Biochem Biophys. 2007; 461(2): 242-6., PMID: 17399679  
DP00552Region 1Jin KS, Kim DY, Rho Y, Le VB, Kwon E, Kim KK, Ree M. "Solution structures of RseA and its complex with RseB." J Synchrotron Radiat. 2008; 15(3): 219-222., PMID: 18421143  
DP00553 Budreck EC, Scheiffele P. "Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses." Eur J Neurosci. 2007; 26(7): 1738-48., PMID: 17897391  
  Otten R, Wood K, Mulder FA. "Comprehensive determination of (3)J (HNHalpha) for unfolded proteins using (13)C'-resolved spin-echo difference spectroscopy." J Biomol NMR. 2009., PMID: 19898942  
 Region 1Paz A, Zeev-Ben-Mordehai T, Lundqvist M, Sherman E, Mylonas E, Weiner L, Haran G, Svergun D, Mulder F, Sussman J, Silman I. "Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3." Biophys J. 2008; 95(4): 1928-44., PMID: 18456828  
DP00554 Eberstadt M, Huang B, Olejniczak ET, Fesik SW. "The lymphoproliferation mutation in Fas locally unfolds the Fas death domain." Nat Struct Biol. 1997; 4(12): 983-5., PMID: 9406545  
 Region 1S . Hiller, A . Kohl, F . Fiorito, T . Herrmann, G . Wider, J . Tschopp, M . Grütter, K . Wüthrich. "NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain." Structure. 2003; 11(10): 1199-1205., PMID: 14527388  
DP00555Region 1Bertoncini CW, Rasia RM, Lamberto GR, Binolfi A, Zweckstetter M, Griesinger C, Fernandez CO. "Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation." J Mol Biol. 2007; 372(3): 708-22., PMID: 17681539  
DP00556 Borgon RA, Vonrhein C, Bricogne G, Bois PR, Izard T. "Crystal structure of human vinculin." Structure. 2004; 12(7): 1189-97., PMID: 15242595  
 Region 1Fillingham I, Gingras AR, Papagrigoriou E, Patel B, Emsley J, Critchley DR, Roberts GC, Barsukov IL. "A Vinculin Binding Domain from the Talin Rod Unfolds to Form a Complex with the Vinculin Head." Structure. 2005; 13(1): 65-74., PMID: 15642262  
DP00557Region 1Zhang H, Tweel B, Li J, Tong L. "Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with CP-640186." Structure. 2004; 12(9): 1683-91., PMID: 15341732  
DP00558 Long SB, Hancock PJ, Kral AM, Hellinga HW, Beese LS. "The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics." Proc Natl Acad Sci U S A. 2001; 98(23): 12948-53., PMID: 11687658  
DP00559 Viola CM, Saridakis V, Christendat D. "Crystal structure of chorismate synthase from Aquifex aeolicus reveals a novel beta alpha beta sandwich topology." Proteins. 2004; 54(1): 166-9., PMID: 14705034  
DP00560_C007Region 1Grzela R, Szolajska E, Ebel C, Madern D, Favier A, Wojtal I, Zagorski W, Chroboczek J. "Virulence factor of potato virus Y, genome-attached terminal protein VPg, is a highly disordered protein." J Biol Chem. 2008; 283(1): 213-21., PMID: 17971447  
 Region 1Nicolas O, Laliberté JF. "The complete nucleotide sequence of turnip mosaic potyvirus RNA." J Gen Virol. 1992; 73(11): 2785-93., PMID: 1431807  
DP00561 Weljie AM, Gagné SM, Vogel HJ. "Solution structure and backbone dynamics of the N-terminal region of the calcium regulatory domain from soybean calcium-dependent protein kinase alpha." Biochemistry. 2004; 43(48): 15131-40., PMID: 15568805  
DP00562 Fan S, Wei Z, Xu H, Gong W. "Crystal structure of human synbindin reveals two conformations of longin domain." Biochem Biophys Res Commun. 2009; 378(3): 338-43., PMID: 18466758  
DP00563 Hinds MG, Smits C, Fredericks-Short R, Risk JM, Bailey M, Huang DC, Day CL. "Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets." Cell Death Differ. 2006., PMID: 16645638  
  Petros AM, Nettesheim DG, Wang Y, Olejniczak ET, Meadows RP, Mack J, Swift K, Matayoshi ED, Zhang H, Thompson CB, Fesik SW. "Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies." Protein Sci. 2000; 9(12): 2528-34., PMID: 11206074  
DP00564 Burton RA, Mattila S, Taparowsky EJ, Post CB. "B-myc: N-terminal recognition of myc binding proteins." Biochemistry. 2006; 45(32): 9857-65., PMID: 16893186  
DP00565 Manalan AS, Klee CB. "Activation of calcineurin by limited proteolysis." Proc. Natl. Acad. Sci. U.S.A.. 1983; 80(14): 4291-5., PMID: 6576338  
 Region 1, Region 3, Region 5Li H, Zhang L, Rao A, Harrison SC, Hogan PG. "Structure of calcineurin in complex with PVIVIT peptide: portrait of a low-affinity signalling interaction." J. Mol. Biol.. 2007; 369(5): 1296-306., PMID: 17498738  
 Region 1, Region 5Kissinger CR, Parge HE, Knighton DR, Lewis CT, Pelletier LA, Tempczyk A, Kalish VJ, Tucker KD, Showalter RE, Moomaw EW, et al. "Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex." Nature. 1995; 378(6557): 641-4., PMID: 8524402  
 Region 1, Region 3, Region 4, Region 5Anglister J, Grzesiek S, Wang AC, Ren H, Klee CB, Bax A. "1H, 13C, 15N nuclear magnetic resonance backbone assignments and secondary structure of human calcineurin B." Biochemistry. 1994; 33(12): 3540-7., PMID: 8142351  
 Region 1, Region 5Jin L, Harrison SC. "Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin." Proc Natl Acad Sci U S A. 2002; 99(21): 13522-6., PMID: 12357034  
 Region 1, Region 2, Region 3, Region 5Anglister J, Ren H, Klee CB, Bax A. "NMR identification of calcineurin B residues affected by binding of a calcineurin A peptide." FEBS Lett.. 1995; 375(1-2): 108-12., PMID: 7498455  
DP00566 Chambers TM, Yamnikova S, Kawaoka Y, Lvov DK, Webster RG. "Antigenic and molecular characterization of subtype H13 hemagglutinin of influenza virus." Virology. 1989; 172(1): 180-8., PMID: 2773315  
 Region 1, Region 2Bullough PA, Hughson FM, Skehel JJ, Wiley DC. "Structure of influenza haemagglutinin at the pH of membrane fusion." Nature. 1994; 371(6492): 37-43., PMID: 8072525  
DP00567 Street MD, Donovan GR, Baldo BA. "Molecular cloning and characterization of the major allergen Myr p II from the venom of the jumper ant Myrmecia pilosula: Myr p I and Myr p II share a common protein leader sequence." Biochim Biophys Acta. 1996; 1305(1-2): 87-97., PMID: 8605256  
 Region 1Zelezetsky I, Pag U, Antcheva N, Sahl HG, Tossi A. "Identification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin." Arch Biochem Biophys. 2005; 434(2): 358-64., PMID: 15639237  
DP00568 Xu HE, Rould MA, Xu W, Epstein JA, Maas RL, Pabo CO. "Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding." Genes Dev. 1999; 13(10): 1263-75., PMID: 10346815  
 Region 1Xu HE, Rould MA, Xu W, Epstein JA, Maas RL, Pabo CO. "Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding." Genes Dev. 1999; 13(10): 1263-75., PMID: 10346815  
DP00569Region 1Verdone G, Doliana R, Corazza A, Colebrooke SA, Spessotto P, Bot S, Bucciotti F, Capuano A, Silvestri A, Viglino P, Campbell ID, Colombatti A, Esposito G. "The Solution Structure of EMILIN1 Globular C1q Domain Reveals a Disordered Insertion Necessary for Interaction with the {alpha}4{beta}1 Integrin." J Biol Chem. 2008; 283(27): 18947-56., PMID: 18463100  
DP00570 Maity TS, Weeks KM. "A threefold RNA-protein interface in the signal recognition particle gates native complex assembly." J Mol Biol. 2007; 369(2): 512-24., PMID: 17434535  
  Oubridge C, Kuglstatter A, Jovine L, Nagai K. "Crystal structure of SRP19 in complex with the S domain of SRP RNA and its implication for the assembly of the signal recognition particle." Mol Cell. 2002; 9(6): 1251-61., PMID: 12086622  
 Region 1Maity TS, Weeks KM. "A threefold RNA-protein interface in the signal recognition particle gates native complex assembly." J Mol Biol. 2007; 369(2): 512-24., PMID: 17434535  
DP00571 Lang R, Kocourek A, Braun M, Tschesche H, Huber R, Bode W, Maskos K. "Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure." J Mol Biol. 2001; 312(4): 731-42., PMID: 11575928  
  Bertini I, Calderone V, Fragai M, Luchinat C, Mangani S, Terni B. "X-ray structures of binary and ternary enzyme-product-inhibitor complexes of matrix metalloproteinases." Angew Chem Int Ed Engl. 2003; 42(23): 2673-6., PMID: 12813751  
  Bertini I, Calderone V, Cosenza M, Fragai M, Lee YM, Luchinat C, Mangani S, Terni B, Turano P. "Conformational variability of matrix metalloproteinases: beyond a single 3D structure." Proc Natl Acad Sci U S A. 2005; 102(15): 5334-9., PMID: 15809432  
 Region 1, Region 2Bertini I, Calderone V, Cosenza M, Fragai M, Lee YM, Luchinat C, Mangani S, Terni B, Turano P. "Conformational variability of matrix metalloproteinases: beyond a single 3D structure." Proc Natl Acad Sci U S A. 2005; 102(15): 5334-9., PMID: 15809432  
DP00573 Acharya R, Fry E, Stuart D, Fox G, Rowlands D, Brown F. "The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution." Nature. 1989; 337(6209): 709-16., PMID: 2537470  
  Cheung A, DeLamarter J, Weiss S, Küpper H. "Comparison of the major antigenic determinants of different serotypes of foot-and-mouth disease virus." J Virol. 1983; 48(2): 451-9., PMID: 6194313  
DP00573_C003 Acharya R, Fry E, Stuart D, Fox G, Rowlands D, Brown F. "The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution." Nature. 1989; 337(6209): 709-16., PMID: 2537470  
  Cheung A, DeLamarter J, Weiss S, Küpper H. "Comparison of the major antigenic determinants of different serotypes of foot-and-mouth disease virus." J Virol. 1983; 48(2): 451-9., PMID: 6194313  
 Region 1, Region 2Acharya R, Fry E, Stuart D, Fox G, Rowlands D, Brown F. "The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution." Nature. 1989; 337(6209): 709-16., PMID: 2537470  
DP00573_C004 Acharya R, Fry E, Stuart D, Fox G, Rowlands D, Brown F. "The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution." Nature. 1989; 337(6209): 709-16., PMID: 2537470  
  Cheung A, DeLamarter J, Weiss S, Küpper H. "Comparison of the major antigenic determinants of different serotypes of foot-and-mouth disease virus." J Virol. 1983; 48(2): 451-9., PMID: 6194313  
 Region 1, Region 2Acharya R, Fry E, Stuart D, Fox G, Rowlands D, Brown F. "The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution." Nature. 1989; 337(6209): 709-16., PMID: 2537470  
DP00573_C005 Acharya R, Fry E, Stuart D, Fox G, Rowlands D, Brown F. "The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution." Nature. 1989; 337(6209): 709-16., PMID: 2537470  
  Cheung A, DeLamarter J, Weiss S, Küpper H. "Comparison of the major antigenic determinants of different serotypes of foot-and-mouth disease virus." J Virol. 1983; 48(2): 451-9., PMID: 6194313  
 Region 1Acharya R, Fry E, Stuart D, Fox G, Rowlands D, Brown F. "The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution." Nature. 1989; 337(6209): 709-16., PMID: 2537470  
DP00573_C006 Acharya R, Fry E, Stuart D, Fox G, Rowlands D, Brown F. "The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution." Nature. 1989; 337(6209): 709-16., PMID: 2537470  
  Cheung A, DeLamarter J, Weiss S, Küpper H. "Comparison of the major antigenic determinants of different serotypes of foot-and-mouth disease virus." J Virol. 1983; 48(2): 451-9., PMID: 6194313  
 Region 1, Region 2Acharya R, Fry E, Stuart D, Fox G, Rowlands D, Brown F. "The three-dimensional structure of foot-and-mouth disease virus at 2.9 A resolution." Nature. 1989; 337(6209): 709-16., PMID: 2537470  
DP00574 Hassler M, Richmond TJ. "The B-box dominates SAP-1-SRF interactions in the structure of the ternary complex." Embo J. 2001; 20(12): 3018-28., PMID: 11406578  
DP00575 Di Lello P, Benison GC, Valafar H, Pitts KE, Summers AO, Legault P, Omichinski JG. "NMR structural studies reveal a novel protein fold for MerB, the organomercurial lyase involved in the bacterial mercury resistance system." Biochemistry. 2004; 43(26): 8322-32., PMID: 15222745  
DP00576 Albrecht M, Golatta M, Wüllner U, Lengauer T. "Structural and functional analysis of ataxin-2 and ataxin-3." Eur J Biochem. 2004; 271(15): 3155-70., PMID: 15265035  
DP00578 Zalkin H. "Structure, function, and regulation of amidophosphoribosyltransferase from prokaryotes." Adv Enzyme Regul. 1983; 21: 225-37., PMID: 6443594  
 Region 1, Region 2, Region 3Smith JL. "Glutamine PRPP amidotransferase: snapshots of an enzyme in action." Curr Opin Struct Biol. 1988; 8(6): 686-94., PMID: 9914248  
DP00579 DiNitto JP, Huber PW. "Mutual induced fit binding of Xenopus ribosomal protein L5 to 5S rRNA." J Mol Biol. 2003; 330(5): 979-92., PMID: 12860121  
DP00580 Batanero E, Ledesma A, Villalba M, Rodríguez R. "Purification, amino acid sequence and immunological characterization of Ole e 6, a cysteine-enriched allergen from olive tree pollen." FEBS Lett. 1997; 410(2-3): 293-6., PMID: 9237648  
 Region 1Treviño MA, García-Mayoral MF, Barral P, Villalba M, Santoro J, Rico M, Rodríguez R, Bruix M. "NMR solution structure of Ole e 6, a major allergen from olive tree pollen." J Mol Biol. 2004; 279(37): 39035-41., PMID: 15247256  
DP00581 Nicely NI, Kosak J, de Serrano V, Mattos C. "Crystal structures of Ral-GppNHp and Ral-GDP reveal two binding sites that are also present in Ras and Rap." Structure. 2004; 12(11): 2025-36., PMID: 15530367  
DP00582 Assadi-Porter FM, Aceti DJ, Markley JL. "Sweetness determinant sites of brazzein, a small, heat-stable, sweet-tasting protein." Arch Biochem Biophys. 2000; 376(2): 259-65., PMID: 10775411  
DP00583 Almog R, Maley F, Maley GF, Maccoll R, Van Roey P. "Three-dimensional structure of the R115E mutant of T4-bacteriophage 2'-deoxycytidylate deaminase." Biochemistry. 2004; 43(43): 13715-23., PMID: 15504034  
DP00584 Kapłon TM, Rymarczyk G, Nocula-Ługowska M, Jakób M, Kochman M, Lisowski M, Szewczuk Z, Ozyhar A. "Starmaker exhibits properties of an intrinsically disordered protein." Biomacromolecules. 2008; 9(8): 2118-25., PMID: 18636772  
DP00586 Phylip LH, Lees WE, Brownsey BG, Bur D, Dunn BM, Winther JR, Gustchina A, Li M, Copeland T, Wlodawer A, Kay J. "The potency and specificity of the interaction between the IA3 inhibitor and its target aspartic proteinase from Saccharomyces cerevisiae." J Biol Chem. 2001; 276(3): 2023-30., PMID: 11042188  
 Region 1Green TB, Ganesh O, Perry K, Smith L, Phylip LH, Logan TM, Hagen SJ, Dunn BM, Edison AS. "IA3, an aspartic proteinase inhibitor from Saccharomyces cerevisiae, is intrinsically unstructured in solution." Biochemistry. 2004; 43(14): 4071-81., PMID: 15065849  
DP00587Region 1Kang N, Chen D, Wang L, Duan L, Liu SR, Tang L, Liu QF, Cui LX, He W. "Rwdd1, a thymus aging related molecule, is a new member of the intrinsically unstructured protein family." Cell Mol Immunol. 2008; 5(5): 333-9., PMID: 18954556  
DP00588_C002Region 1Duvignaud JB, Savard C, Fromentin R, Majeau N, Leclerc D, Gagné SM. "Structure and dynamics of the N-terminal half of hepatitis C virus core protein: An intrinsically unstructured protein." Biochem Biophys Res Commun. 2008; 378(1): 27-31., PMID: 18992225  
 Region 2Ladaviere, L., Deleage, G., Montserret, R., Dalbon, P., Jolivet, M., Penin, F. "Structural Analysis of the Immunodominant Antigenic Region of the Hepatitis C Virus Capsid Protein by NMR." unpublished. . 
DP00588_C010 Penin F, Brass V, Appel N, Ramboarina S, Montserret R, Ficheux D, Blum HE, Bartenschlager R, Moradpour D. "Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A." J. Biol. Chem.. 2004; 279(39): 40835-43., PMID: 15247283  
 Region 1, Region 2, Region 3, Region 4Penin F, Brass V, Appel N, Ramboarina S, Montserret R, Ficheux D, Blum HE, Bartenschlager R, Moradpour D. "Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A." J. Biol. Chem.. 2004; 279(39): 40835-43., PMID: 15247283  
DP00591 Szilvay GR, Blenner MA, Shur O, Cropek DM, Banta S. "A FRET-based method for probing the conformational behavior of an intrinsically disordered repeat domain from Bordetella pertussis adenylate cyclase." Biochemistry. 2009; 48(47): 11273-82., PMID: 19860484  
  Chenal A, Guijarro JI, Raynal B, Delepierre M, Ladant D. "RTX calcium binding motifs are intrinsically disordered in the absence of calcium: implication for protein secretion." J. Biol. Chem.. 2008; 284(3): 1781-9., PMID: 19015266  
 Region 1Chenal A, Guijarro JI, Raynal B, Delepierre M, Ladant D. "RTX calcium binding motifs are intrinsically disordered in the absence of calcium: implication for protein secretion." J Biol Chem. 2009; 284(3): 1781-9., PMID: 19015266  
 Region 1Sotomayor Pérez AC, Karst JC, Davi M, Guijarro JI, Ladant D, Chenal A. "Characterization of the regions involved in the calcium-induced folding of the intrinsically disordered RTX motifs from the bordetella pertussis adenylate cyclase toxin." 2010; 397(2): 534-549., PMID: 20096704  
DP00592Region 1Kleerekoper QK, Putkey JA. "PEP-19: An intrinsically disordered regulator of calmodulin signaling." J Biol Chem. 2008., PMID: 19106096  
DP00594_A002 Dziedzic-Letka A, Rymarczyk G, Kapłon TM, Górecki A, Szamborska-Gbur A, Wojtas M, Dobryszycki P, Ożyhar A. "Intrinsic disorder of Drosophila melanogaster hormone receptor 38 N-terminal domain." 2010., PMID: 21064127  
 Region 1Dziedzic-Letka A, Rymarczyk G, Kapłon TM, Górecki A, Szamborska-Gbur A, Wojtas M, Dobryszycki P, Ożyhar A. "Intrinsic disorder of Drosophila melanogaster hormone receptor 38 N-terminal domain." 2010., PMID: 21064127  
DP00600Region 1Timsit Y, Acosta Z, Allemand F, Chiaruttini C, Springer M. "The role of disordered ribosomal protein extensions in the early steps of eubacterial 50 s ribosomal subunit assembly." Int J Mol Sci. 2009; 10(3): 817-34., PMID: 19399222  
 Region 2Timsit, Youri, Fréderic Allemand, Claude Chiaruttini, and Mathias Springer. "Coexistence of two protein folding states in the crystal structure of ribosomal protein L20." Embo J. 2006; 7(10): 1013-1018., PMID: 1618378  
DP00605Region 1Hall J, Karplus PA, Barbar E. "Multivalency in the assembly of intrinsically disordered dynein intermediate chain." J Biol Chem. 2009; 284(48): 33115-21., PMID: 19759397  
DP00606Region 1Kovacs D, Kalmar E, Torok Z, Tompa P. "Chaperone Activity of ERD10 and ERD14, Two Disordered Stress-Related Plant Proteins." Plant Physiol. : 381-390., PMID: 18359842  
 Region 1Mouillon JM, Gustafsson P, Harryson P. "Structural investigation of disordered stress proteins. Comparison of full-length dehydrins with isolated peptides of their conserved segments." Plant Physiol. 2006; 141: 638-650., PMID: 16565295  
DP00607 Condo I, Ventura N, Malisan F, Rufini A, Tomassini B, Testi R. "In vivo maturation of human frataxin." Hum. Mol. Genet.. 2007; 16(13): 1534-40., PMID: 17468497  
 Region 1Prischi F, Giannini C, Adinolfi S, Pastore A. "The N-terminus of mature human frataxin is intrinsically unfolded." FEBS J. 2009., PMID: 19843162  
DP00608 Wang X, Zhang S, Zhang J, Huang X, Xu C, Wang W, Liu Z, Wu J, Shi Y. "A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR." J Biol Chem. 2009., PMID: 20007319  
 Region 1Wang X, Zhang S, Zhang J, Huang X, Xu C, Wang W, Liu Z, Wu J, Shi Y. "A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR." J Biol Chem. 2009., PMID: 20007319  
DP00609 Richardson LG, Jelokhani-Niaraki M, Smith MD. "The acidic domains of the Toc159 chloroplast preprotein receptor family are intrinsically disordered protein domains." BMC Biochem. 2009; 10(1): 35., PMID: 20042108  
 Region 1, Region 2, Region 3, Region 4Richardson LG, Jelokhani-Niaraki M, Smith MD. "The acidic domains of the Toc159 chloroplast preprotein receptor family are intrinsically disordered protein domains." BMC Biochem. 2009; 10(1): 35., PMID: 20042108  
DP00610 Richardson LG, Jelokhani-Niaraki M, Smith MD. "The acidic domains of the Toc159 chloroplast preprotein receptor family are intrinsically disordered protein domains." BMC Biochem. 2009; 10(1): 35., PMID: 20042108  
 Region 1Richardson LG, Jelokhani-Niaraki M, Smith MD. "The acidic domains of the Toc159 chloroplast preprotein receptor family are intrinsically disordered protein domains." BMC Biochem. 2009; 10(1): 35., PMID: 20042108  
DP00611 Li C, Andrake M, Dunbrack R, Enders GH. "A bifunctional regulatory element in human somatic wee1 mediates cyclin a/cdk2 binding and crm1-dependent nuclear export." Mol Cell Biol. ; 30(1): 116-30., PMID: 19858290  
 Region 1Li C, Andrake M, Dunbrack R, Enders GH. "A bifunctional regulatory element in human somatic wee1 mediates cyclin a/cdk2 binding and crm1-dependent nuclear export." Mol Cell Biol. ; 30(1): 116-30., PMID: 19858290  
DP00613 Halevi S, McKay J, Palfreyman M, Yassin L, Eshel M, Jorgensen E, Treinin M. "The C. elegans ric-3 gene is required for maturation of nicotinic acetylcholine receptors." EMBO J. 2002; 21(5): 1012-20., PMID: PMC125878  
  Biala Y, Liewald JF, Ben-Ami HC, Gottschalk A, Treinin M. "The conserved RIC-3 coiled-coil domain mediates receptor-specific interactions with nicotinic acetylcholine receptors." Mol Biol Cell. 2009; 20(5): 1419-27., PMID: 19116311  
  Ben-Ami HC, Yassin L, Farah H, Michaeli A, Eshel M, Treinin M. "RIC-3 affects properties and quantity of nicotinic acetylcholine receptors via a mechanism that does not require the coiled-coil domains." J Biol Chem. 2005; 280(30): 28053-60., PMID: 15932871  
  Halevi S, Yassin L, Eshel M, Sala F, Sala S, Criado M, Treinin M. "Conservation within the RIC-3 gene family. Effectors of mammalian nicotinic acetylcholine receptor expression." J Biol Chem. 2003; 278(36): 34411-7., PMID: 12821669  
  Shteingauz A, Cohen E, Biala Y, Treinin M. "The BTB-MATH protein BATH-42 interacts with RIC-3 to regulate maturation of nicotinic acetylcholine receptors." J Cell Sci. 2009; 122(6): 807-12., PMID: 19223395  
 Region 1Cohen Ben-Ami H, Biala Y, Farah H, Elishevitz E, Battat E, Treinin M. "Receptor and subunit specific interactions of RIC-3 with nicotinic acetylcholine receptors." Biochemistry. 2009; 48(51): 12329-36., PMID: 19899809  
DP00614Region 1Espinoza-Fonseca LM, Wong-Ramirez C, Trujillo-Ferrara JG. "Tyr74 is essential for the formation, stability and function of Plasmodium falciparum triosephosphate isomerase dimer." Arch Biochem Biophys. 2010; 494(1): 46-57., PMID: 19914198  
 Region 1, Region 2Velanker S S, Ray S S, Gokhale R S, Suma S, Balaram H, Balaram P, Murthy M R. "Triosephosphate isomerase from Plasmodium falciparum: the crystal structure provides insights into antimalarial drug design." Structure (London, England : 1993). 1997; 5(6): 751-61., PMID: 9261072  
DP00615_C010Region 1, Region 2, Region 3Tellinghuisen TL, Marcotrigiano J, Rice CM. "Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase." Nature. 2005; 435(7040): 374-9., PMID: 15902263  
 Region 1Love RA, Brodsky O, Hickey MJ, Wells PA, Cronin CN. "Crystal structure of a novel dimeric form of NS5A domain I protein from hepatitis C virus." J. Virol.. 2009; 83(9): 4395-403., PMID: 19244328  
 Region 1, Region 2, Region 3Tellinghuisen TL, Marcotrigiano J, Gorbalenya AE, Rice CM. "The NS5A protein of hepatitis C virus is a zinc metalloprotein." J. Biol. Chem.. 2004; 279(47): 48576-87., PMID: 15339921  
 Region 1, Region 2, Region 3Tellinghuisen TL, Foss KL, Treadaway JC, Rice CM. "Identification of residues required for RNA replication in domains II and III of the hepatitis C virus NS5A protein." J. Virol.. 2007; 82(3): 1073-83., PMID: 18032500  
DP00616 Duchardt F, Ruttekolk IR, Verdurmen WP, Lortat-Jacob H, Burck J, Hufnagel H, Fischer R, van den Heuvel M, Lowik DW, Vuister GW, Ulrich A, de Waard M, Brock R. "A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency." J Biol Chem. 2009; 284(52): 36099-108., PMID: 19858187  
 Region 1Duchardt F, Ruttekolk IR, Verdurmen WP, Lortat-Jacob H, Burck J, Hufnagel H, Fischer R, van den Heuvel M, Lowik DW, Vuister GW, Ulrich A, de Waard M, Brock R. "A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency." J Biol Chem. 2009; 284(52): 36099-108., PMID: 19858187  
DP00618 Absmanner B, Schmeiser V, Kampf M, Lehle L. "Biochemical characterization, membrane association and identification of amino acids essential for function of Alg11 from Saccharomyces cerevisiae, an alpha1,2-mannosyltransferase, catalyzing two sequential glycosylation steps in the formation of the lipid-linked core oligosaccharide." Biochem J. 2010; 426(2): 205-17., PMID: 19929855  
 Region 1Absmanner B, Schmeiser V, Kampf M, Lehle L. "Biochemical characterization, membrane association and identification of amino acids essential for function of Alg11 from Saccharomyces cerevisiae, an alpha1,2-mannosyltransferase, catalyzing two sequential glycosylation steps in the formation of the lipid-linked core oligosaccharide." Biochem J. 2010; 426(2): 205-17., PMID: 19929855  
 Region 1Breton C, Snajdrová L, Jeanneau C, Koca J, Imberty A. "Structures and mechanisms of glycosyltransferases." Glycobiology. 2005; 16(2): 29R-37R., PMID: 16037492  
 Region 1Qasba PK, Ramakrishnan B, Boeggeman E. "Substrate-induced conformational changes in glycosyltransferases." Trends Biochem. Sci.. 2005; 30(1): 53-62., PMID: 15653326  
 Region 1Hu Y, Chen L, Ha S, Gross B, Falcone B, Walker D, Mokhtarzadeh M, Walker S. "Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases." Proc. Natl. Acad. Sci. U.S.A.. 2003; 100(3): 845-9., PMID: 12538870  
 Region 1Wrabl JO, Grishin NV. "Homology between O-linked GlcNAc transferases and proteins of the glycogen phosphorylase superfamily." J. Mol. Biol.. 2001; 314(3): 365-74., PMID: 11846551  
DP00619 Jeyakanthan J, Drevland RM, Gayathri DR, Velmurugan D, Shinkai A, Kuramitsu S, Yokoyama S, Graham DE. "Substrate specificity determinants of the methanogen homoaconitase enzyme: structure and function of the small subunit." Biochemistry. 2010; 49(12): 2687-2696., PMID: 20170198  
 Region 1Jeyakanthan J, Drevland RM, Gayathri DR, Velmurugan D, Shinkai A, Kuramitsu S, Yokoyama S, Graham DE. "Substrate specificity determinants of the methanogen homoaconitase enzyme: structure and function of the small subunit." Biochemistry. 2010; 49(12): 2687-2696., PMID: 20170198  
DP00620Region 1Omi R, Kurokawa S, Mihara H, Hayashi H, Goto M, Miyahara I, Kurihara T, Hirotsu K, Esaki N. "Reaction mechanism and molecular basis for selenium/sulfur discrimination of selenocysteine lyase." J Biol Chem. 2010; 285(16): 12133-12139., PMID: 20164179  
DP00621Region 1Major B, Kardos J, Kékesi KA, Lorincz Z, Závodszky P, Gál P. "Calcium-dependent conformational flexibility of a CUB domain controls activation of the complement serine protease C1r." J Biol Chem. 2010; 285(16): 11863-11869., PMID: 20178990  
DP00622 Fasshauer D, Otto H, Eliason WK, Jahn R, Brunger AT. "Structural changes are associated with soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor complex formation." J Biol Chem. 1997; 272(44): 28036-41., PMID: 9346956 brunger@stanford.edu
  Ellena JF, Liang B, Wiktor M, Stein A, Cafiso DS, Jahn R, Tamm LK. "Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation." Proc Natl Acad Sci U S A. 2009; 106(48): 20306-11., PMID: 19918058  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Ellena JF, Liang B, Wiktor M, Stein A, Cafiso DS, Jahn R, Tamm LK. "Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation." Proc Natl Acad Sci U S A. 2009; 106(48): 20306-11., PMID: 19918058  
 Region 1Fasshauer D, Otto H, Eliason WK, Jahn R, Brunger AT. "Structural changes are associated with soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor complex formation." J Biol Chem. 1997; 272(44): 28036-41., PMID: 9346956 brunger@stanford.edu
DP00623 Tan XX, Bondos S, Li L, Matthews KS. "Transcription activation by ultrabithorax Ib protein requires a predicted alpha-helical region." Biochemistry. 2002; 41(8): 2774-85., PMID: 11851425  
 Region 1, Region 2, Region 3Liu Y, Matthews KS, Bondos SE. "Multiple intrinsically disordered sequences alter DNA binding by the homeodomain of the Drosophila hox protein ultrabithorax." J Biol Chem. 2008; 283(30): 20874-87., PMID: 18508761  
 Region 1, Region 2Tan XX, Bondos S, Li L, Matthews KS. "Transcription activation by ultrabithorax Ib protein requires a predicted alpha-helical region." Biochemistry. 2002; 41(8): 2774-85., PMID: 11851425  
 Region 3Krasnow MA, Saffman EE, Kornfeld K, Hogness DS. "Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells." Cell. 1989; 57(6): 1031-43., PMID: 2567632  
 Region 1, Region 3Gavis ER, Hogness DS. "Phosphorylation, expression and function of the Ultrabithorax protein family in Drosophila melanogaster." Development. 1991; 112(4): 1077-93., PMID: 1682129  
 Region 3Johnson FB, Parker E, Krasnow MA. "Extradenticle protein is a selective cofactor for the Drosophila homeotics: role of the homeodomain and YPWM amino acid motif in the interaction." Proc Natl Acad Sci U S A. 1995; 92(3): 739-43., PMID: 7846045  
 Region 3Liu Y, Matthews KS, Bondos SE. "Internal regulatory interactions determine DNA binding specificity by a Hox transcription factor." J Mol Biol. 2009; 390(4): 760-64., PMID: 19481089  
DP00624 Singh VK, Pacheco I, Uversky VN, Smith SP, MacLeod RJ, Jia Z. "Intrinsically disordered human C/EBP homologous protein regulates biological activity of colon cancer cells during calcium stress." J Mol Biol. 2008; 380(2): 313-26., PMID: 18534616  
 Region 1Singh VK, Pacheco I, Uversky VN, Smith SP, MacLeod RJ, Jia Z. "Intrinsically disordered human C/EBP homologous protein regulates biological activity of colon cancer cells during calcium stress." J Mol Biol. 2008; 380(2): 313-26., PMID: 18534616  
DP00625Region 1Meinke G, Ezeokonkwo C, Balbo P, Stafford W, Moore C, Bohm A. "Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically disordered protein." 2008; 47(26): 6859-6869., PMID: 18537269  
DP00626 Simon SM, Sousa FJ, Mohana-Borges R, Walker GC. "Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products." Proc Natl Acad Sci U S A. 2008; 105(4): 1152-7., PMID: 18216271  
  Ferentz AE, Walker GC, Wagner G. "Converting a DNA damage checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD'2C)." EMBO J.. 2001; 20(15): 4287-98., PMID: 11483531  
  Peat TS, Frank EG, McDonald JP, Levine AS, Woodgate R, Hendrickson WA. "Structure of the UmuD' protein and its regulation in response to DNA damage." Nature. 1996; 380(6576): 727-30., PMID: 8614470  
  Peat TS, Frank EG, McDonald JP, Levine AS, Woodgate R, Hendrickson WA. "The UmuD' protein filament and its potential role in damage induced mutagenesis." Structure. 1996; 4(12): 1401-12., PMID: 8994967  
 Region 1Simon SM, Sousa FJ, Mohana-Borges R, Walker GC. "Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products." Proc Natl Acad Sci U S A. 2008; 105(4): 1152-7., PMID: 18216271  
DP00626_C001 Simon SM, Sousa FJ, Mohana-Borges R, Walker GC. "Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products." Proc Natl Acad Sci U S A. 2008; 105(4): 1152-7., PMID: 18216271  
  Ferentz AE, Walker GC, Wagner G. "Converting a DNA damage checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD'2C)." EMBO J.. 2001; 20(15): 4287-98., PMID: 11483531  
  Peat TS, Frank EG, McDonald JP, Levine AS, Woodgate R, Hendrickson WA. "Structure of the UmuD' protein and its regulation in response to DNA damage." Nature. 1996; 380(6576): 727-30., PMID: 8614470  
  Peat TS, Frank EG, McDonald JP, Levine AS, Woodgate R, Hendrickson WA. "The UmuD' protein filament and its potential role in damage induced mutagenesis." Structure. 1996; 4(12): 1401-12., PMID: 8994967  
 Region 1, Region 2Simon SM, Sousa FJ, Mohana-Borges R, Walker GC. "Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products." Proc Natl Acad Sci U S A. 2008; 105(4): 1152-7., PMID: 18216271  
DP00627 John SP, Wang T, Steffen S, Longhi S, Schmaljohn CS, Jonsson CB. "Ebola virus VP30 is an RNA binding protein." J Virol. 2007; 81(17): 8967-76., PMID: 17567691  
 Region 1John SP, Wang T, Steffen S, Longhi S, Schmaljohn CS, Jonsson CB. "Ebola virus VP30 is an RNA binding protein." J Virol. 2007; 81(17): 8967-76., PMID: 17567691  
DP00628 Nanga RP, Brender JR, Vivekanandan S, Popovych N, Ramamoorthy A. "NMR structure in a membrane environment reveals putative amyloidogenic regions of the SEVI precursor peptide PAP(248-286)." J Am Chem Soc. 2009; 131(49): 17972-9., PMID: 19995078  
 Region 1Nanga RP, Brender JR, Vivekanandan S, Popovych N, Ramamoorthy A. "NMR structure in a membrane environment reveals putative amyloidogenic regions of the SEVI precursor peptide PAP(248-286)." J Am Chem Soc. 2009; 131(49): 17972-9., PMID: 19995078  
 Region 1Jakob CG, Lewinski K, Kuciel R, Ostrowski W, Lebioda L. "Crystal structure of human prostatic acid phosphatase ." Prostate. 2000; 42(3): 211-8., PMID: 10639192  
DP00629 Houben K, Marion D, Tarbouriech N, Ruigrok RW, Blanchard L. "Interaction of the C-terminal domains of sendai virus N and P proteins: comparison of polymerase-nucleocapsid interactions within the paramyxovirus family." J Virol. 2007; 81(13): 6807-16., PMID: 17459940  
 Region 1Houben K, Marion D, Tarbouriech N, Ruigrok RW, Blanchard L. "Interaction of the C-terminal domains of sendai virus N and P proteins: comparison of polymerase-nucleocapsid interactions within the paramyxovirus family." J Virol. 2007; 81(13): 6807-16., PMID: 17459940  
DP00630 Singh VK, Zhou Y, Marsh JA, Uversky VN, Forman-Kay JD, Liu J, Jia Z. "Synuclein-gamma targeting peptide inhibitor that enhances sensitivity of breast cancer cells to antimicrotubule drugs." Cancer Res. 2007; 67(2): 626-33., PMID: 17234772  
 Region 1Singh VK, Zhou Y, Marsh JA, Uversky VN, Forman-Kay JD, Liu J, Jia Z. "Synuclein-gamma targeting peptide inhibitor that enhances sensitivity of breast cancer cells to antimicrotubule drugs." Cancer Res. 2007; 67(2): 626-33., PMID: 17234772  
DP00631 Borg M, Mittag T, Pawson T, Tyers M, Forman-Kay JD, Chan HS. "Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity." Proc Natl Acad Sci U S A. 2007; 104(23): 9650-5., PMID: 17522259  
  Mittag T, Marsh J, Grishaev A, Orlicky S, Lin H, Sicheri F, Tyers M, Forman-Kay JD. "Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase." Structure. 2010; 18(4): 494-506., PMID: 20399178  
  Nash P, Tang X, Orlicky S, Chen Q, Gertler FB, Mendenhall MD, Sicheri F, Pawson T, Tyers M. "Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication." Nature. 2001; 414(6863): 514-21., PMID: 11734834  
  Mittag T, Orlicky S, Choy WY, Tang X, Lin H, Sicheri F, Kay LE, Tyers M, Forman-Kay JD. "Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor." Proc. Natl. Acad. Sci. U.S.A.. 2008; 105(46): 17772-7., PMID: 17660831  
 Region 1Borg M, Mittag T, Pawson T, Tyers M, Forman-Kay JD, Chan HS. "Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity." Proc Natl Acad Sci U S A. 2007; 104(23): 9650-5., PMID: 17522259  
 Region 1Mittag T, Marsh J, Grishaev A, Orlicky S, Lin H, Sicheri F, Tyers M, Forman-Kay JD. "Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase." Structure. 2010; 18(4): 494-506., PMID: 20399178  
 Region 1Mittag T, Orlicky S, Choy WY, Tang X, Lin H, Sicheri F, Kay LE, Tyers M, Forman-Kay JD. "Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor." Proc. Natl. Acad. Sci. U.S.A.. 2008; 105(46): 17772-7., PMID: 17660831  
 Region 1Nash P, Tang X, Orlicky S, Chen Q, Gertler FB, Mendenhall MD, Sicheri F, Pawson T, Tyers M. "Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication." Nature. 2001; 414(6863): 514-21., PMID: 11734834  
DP00632 Ng KP, Potikyan G, Savene RO, Denny CT, Uversky VN, Lee KA. "Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins." Proc Natl Acad Sci U S A. 2007; 104(2): 479-84., PMID: 17202261  
 Region 1Ng KP, Potikyan G, Savene RO, Denny CT, Uversky VN, Lee KA. "Multiple aromatic side chains within a disordered structure are critical for transcription and transforming activity of EWS family oncoproteins." Proc Natl Acad Sci U S A. 2007; 104(2): 479-84., PMID: 17202261  
 Region 1Feng L, Lee KA. "A repetitive element containing a critical tyrosine residue is required for transcriptional activation by the EWS/ATF1 oncogene." Oncogene. 2001; 20(31): 4161-8., PMID: 11464282  
 Region 1Tan AY, Manley JL. "The TET family of proteins: functions and roles in disease." J Mol Cell Biol. 2009; 1(2): 82-92., PMID: 19783543  
DP00633 Teufel DP, Freund SM, Bycroft M, Fersht AR. "Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53." Proc Natl Acad Sci U S A. 2007; 104(17): 7009-14., PMID: 17438265  
 Region 1Teufel DP, Freund SM, Bycroft M, Fersht AR. "Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53." Proc Natl Acad Sci U S A. 2007; 104(17): 7009-14., PMID: 17438265  
DP00634 Stollar EJ, Garcia B, Chong PA, Rath A, Lin H, Forman-Kay JD, Davidson AR. "Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p." J. Biol. Chem.. 2009; 284(39): 26918-27., PMID: 19590096  
  Fazi B, Cope MJ, Douangamath A, Ferracuti S, Schirwitz K, Zucconi A, Drubin DG, Wilmanns M, Cesareni G, Castagnoli L. "Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis." J. Biol. Chem.. 2001; 277(7): 5290-8., PMID: 11668184  
 Region 1, Region 2, Region 3Fazi B, Cope MJ, Douangamath A, Ferracuti S, Schirwitz K, Zucconi A, Drubin DG, Wilmanns M, Cesareni G, Castagnoli L. "Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis." J. Biol. Chem.. 2001; 277(7): 5290-8., PMID: 11668184  
 Region 1, Region 2, Region 3Beltrao P, Serrano L. "Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions." PLoS Comput. Biol.. 2005; 1(3): e26., PMID: 16110343  
 Region 1, Region 2, Region 3Stollar EJ, Garcia B, Chong PA, Rath A, Lin H, Forman-Kay JD, Davidson AR. "Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p." J. Biol. Chem.. 2009; 284(39): 26918-27., PMID: 19590096  
DP00635 Prag G, Watson H, Kim YC, Beach BM, Ghirlando R, Hummer G, Bonifacino JS, Hurley JH. "The Vps27/Hse1 complex is a GAT domain-based scaffold for ubiquitin-dependent sorting." Dev. Cell. 2007; 12(6): 973-86., PMID: 17543868  
 Region 1Prag G, Watson H, Kim YC, Beach BM, Ghirlando R, Hummer G, Bonifacino JS, Hurley JH. "The Vps27/Hse1 complex is a GAT domain-based scaffold for ubiquitin-dependent sorting." Dev. Cell. 2007; 12(6): 973-86., PMID: 17543868  
 Region 1Beltrao P, Serrano L. "Comparative genomics and disorder prediction identify biologically relevant SH3 protein interactions." PLoS Comput. Biol.. 2005; 1(3): e26., PMID: 16110343  
DP00636 Stock MF, Chu J, Hackney DD. "The kinesin family member BimC contains a second microtubule binding region attached to the N terminus of the motor domain." J Biol Chem. 2003; 278(52): 52315-22., PMID: 14530265  
 Region 1Stock MF, Chu J, Hackney DD. "The kinesin family member BimC contains a second microtubule binding region attached to the N terminus of the motor domain." J Biol Chem. 2003; 278(52): 52315-22., PMID: 14530265  
DP00637 Jin L, Briggs SL, Chandrasekhar S, Chirgadze NY, Clawson DK, Schevitz RW, Smiley DL, Tashjian AH, Zhang F. "Crystal structure of human parathyroid hormone 1-34 at 0.9-A resolution." J. Biol. Chem.. 2000; 275(35): 27238-44., PMID: 10837469  
 Region 1Shimizu N, Guo J, Gardella TJ. "Parathyroid hormone (PTH)-(1-14) and -(1-11) analogs conformationally constrained by alpha-aminoisobutyric acid mediate full agonist responses via the juxtamembrane region of the PTH-1 receptor." J Biol Chem. 2001; 276(52): 49003-12., PMID: 11604398  
 Region 1Jin L, Briggs SL, Chandrasekhar S, Chirgadze NY, Clawson DK, Schevitz RW, Smiley DL, Tashjian AH, Zhang F. "Crystal structure of human parathyroid hormone 1-34 at 0.9-A resolution." J. Biol. Chem.. 2000; 275(35): 27238-44., PMID: 10837469  
DP00638 Song J, Guo LW, Muradov H, Artemyev NO, Ruoho AE, Markley JL. "Intrinsically disordered gamma-subunit of cGMP phosphodiesterase encodes functionally relevant transient secondary and tertiary structure." Proc Natl Acad Sci U S A. 2008; 105(5): 1505-10., PMID: 18230733  
 Region 1, Region 2Song J, Guo LW, Muradov H, Artemyev NO, Ruoho AE, Markley JL. "Intrinsically disordered gamma-subunit of cGMP phosphodiesterase encodes functionally relevant transient secondary and tertiary structure." Proc Natl Acad Sci U S A. 2008; 105(5): 1505-10., PMID: 18230733  
DP00640 Karlin D, Ferron F, Canard B, Longhi S. "Structural disorder and modular organization in Paramyxovirinae N and P." 2003; 84(Pt 12): 3239-52., PMID: 14645906 sonia.longhi@afmb.un
iv-mrs.fr
 Region 1Karlin D, Longhi S, Canard B. "Substitution of two residues in the measles virus nucleoprotein results in an impaired self-association." Virology. 2002; 302(2): 420-432., PMID: 12441086  
DP00641Region 1Crump MP, Rajarathnam K, Kim KS, Clark-Lewis I, Sykes BD. "Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation." J Biol Chem. 1998; 273(35): 22471-22479., PMID: 9712872  
DP00642 Angelucci F, Sayed AA, Williams DL, Boumis G, Brunori M, Dimastrogiovanni D, Miele AE, Pauly F, Bellelli A. "Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects." J Biol Chem. 2009; 284(42): 28977-85., PMID: 19710012  
 Region 1Angelucci F, Sayed AA, Williams DL, Boumis G, Brunori M, Dimastrogiovanni D, Miele AE, Pauly F, Bellelli A. "Inhibition of Schistosoma mansoni thioredoxin-glutathione reductase by auranofin: structural and kinetic aspects." J Biol Chem. 2009; 284(42): 28977-85., PMID: 19710012  
DP00643 Hinds MG, Smits C, Fredericks-Short R, Risk JM, Bailey M, Huang DC, Day CL. "Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets." Cell Death Differ. 2006., PMID: 16645638  
DP00643_A002 Hinds MG, Smits C, Fredericks-Short R, Risk JM, Bailey M, Huang DC, Day CL. "Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets." Cell Death Differ. 2006., PMID: 16645638  
 Region 1Hinds MG, Smits C, Fredericks-Short R, Risk JM, Bailey M, Huang DC, Day CL. "Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets." Cell Death Differ. 2006., PMID: 16645638  
DP00644Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Keizer DW, Crump MP, Lee TW, Slupsky CM, Clark-Lewis I, Sykes BD. "Human CC chemokine I-309, structural consequences of the additional disulfide bond." Biochemistry. 2000; 39(20): 6053-9., PMID: 10821677  
DP00645 Hinds MG, Smits C, Fredericks-Short R, Risk JM, Bailey M, Huang DC, Day CL. "Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets." Cell Death Differ. 2006., PMID: 16645638  
 Region 1Hinds MG, Smits C, Fredericks-Short R, Risk JM, Bailey M, Huang DC, Day CL. "Bim, Bad and Bmf: intrinsically unstructured BH3-only proteins that undergo a localized conformational change upon binding to prosurvival Bcl-2 targets." Cell Death Differ. 2006., PMID: 16645638  
DP00646Region 1Bouvier D, Spagnol G, Chenavas S, Kieken F, Vitrac H, Brownell S, Kellezi A, Forge V, Sorgen PL. "Characterization of the structure and intermolecular interactions between the connexin40 and connexin43 carboxyl-terminal and cytoplasmic loop domains." J Biol Chem. 2009; 284(49): 34257-71., PMID: 19808665  
DP00647Region 1Breusted DA, Chatwell L, Skerra A. "A new crystal form of human tear lipocalin reveals high flexibility in the loop region and induced fit in the ligand cavity." Acta Crystallogr D Biol Crystallogr. 2009; 65(Pt 10): 1118-25., PMID: 19770509  
 Region 1Breustedt DA, Korndörfer IP, Redl B, Skerra A. "The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands." J Biol Chem. 2005; 280(1): 484-93., PMID: 15489503  
DP00650 Foucault M, Mayol K, Receveur-Brechot V, Bussat MC, Klinguer-Hamour C, Verrier B, Beck A, Haser R, Gouet P, Guillon C. "UV and X-ray structural studies of a 101-residue long Tat protein from a HIV-1 primary isolate and of its mutated, detoxified, vaccine candidate." Proteins. 2009., PMID: 20034112  
 Region 1Foucault M, Mayol K, Receveur-Brechot V, Bussat MC, Klinguer-Hamour C, Verrier B, Beck A, Haser R, Gouet P, Guillon C. "UV and X-ray structural studies of a 101-residue long Tat protein from a HIV-1 primary isolate and of its mutated, detoxified, vaccine candidate." Proteins. 2009., PMID: 20034112  
DP00651_C007Region 1Acevedo ML, Arbildúa JJ, Monasterio O, Toledo H, León O. "Role of the 207-218 peptide region of Moloney murine leukemia virus integrase in enzyme catalysis." Arch Biochem Biophys. 2009., PMID: 20026028  
DP00652 Galaleldeen A, Strange RW, Whitson LJ, Antonyuk SV, Narayana N, Taylor AB, Schuermann JP, Holloway SP, Hasnain SS, Hart PJ. "Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A." Arch Biochem Biophys. 2009., PMID: 19800308  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6Galaleldeen A, Strange RW, Whitson LJ, Antonyuk SV, Narayana N, Taylor AB, Schuermann JP, Holloway SP, Hasnain SS, Hart PJ. "Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A." Arch Biochem Biophys. 2009., PMID: 19800308  
DP00653 Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR. "The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation." J Mol Biol. 2009; 394(5): 944-56., PMID: 19804783  
 Region 1Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR. "The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation." J Mol Biol. 2009; 394(5): 944-56., PMID: 19804783  
DP00654 Arent S, Christensen CE, Pye VE, Nørgaard A, Henriksen A. "The multifunctional protein in peroxisomal beta-oxidation: structure and substrate specificity of the arabidopsis thaliana protein MFP2." J. Biol. Chem.. 2010; 285(31): 24066-77., PMID: 20463021  
 Region 1, Region 2, Region 3Arent S, Christensen CE, Pye VE, Nørgaard A, Henriksen A. "The multifunctional protein in peroxisomal beta-oxidation: structure and substrate specificity of the arabidopsis thaliana protein MFP2." J. Biol. Chem.. 2010; 285(31): 24066-77., PMID: 20463021  
DP00655 Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR. "The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation." J Mol Biol. 2009; 394(5): 944-56., PMID: 19804783  
 Region 1Goult BT, Bouaouina M, Harburger DS, Bate N, Patel B, Anthis NJ, Campbell ID, Calderwood DA, Barsukov IL, Roberts GC, Critchley DR. "The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation." J Mol Biol. 2009; 394(5): 944-56., PMID: 19804783  
DP00656 Rajasekar K, Muntaha ST, Tame JR, Kommareddy S, Morris G, Wharton CW, Thomas CM, White SA, Hyde EI, Scott DJ. "Order and disorder in the domain organization of the plasmid partition protein KorB." J. Biol. Chem.. 2010; 285(20): 15440-9., PMID: 20200158  
 Region 1, Region 2Rajasekar K, Muntaha ST, Tame JR, Kommareddy S, Morris G, Wharton CW, Thomas CM, White SA, Hyde EI, Scott DJ. "Order and disorder in the domain organization of the plasmid partition protein KorB." J. Biol. Chem.. 2010; 285(20): 15440-9., PMID: 20200158  
DP00657Region 1Mouillon JM, Gustafsson P, Harryson P. "Structural investigation of disordered stress proteins. Comparison of full-length dehydrins with isolated peptides of their conserved segments." Plant Physiol. 2006; 141: 638-650., PMID: 16565295  
DP00658Region 1Mouillon JM, Gustafsson P, Harryson P. "Structural investigation of disordered stress proteins. Comparison of full-length dehydrins with isolated peptides of their conserved segments." Plant Physiol. 2006; 141: 638-650., PMID: 16565295  
DP00659 Buczek P, Horvath MP. "Structural reorganization and the cooperative binding of single-stranded telomere DNA in Sterkiella nova." J Biol Chem. 2006; 281(52): 40124-34., PMID: 17082188  
 Region 1Buczek P, Horvath MP. "Structural reorganization and the cooperative binding of single-stranded telomere DNA in Sterkiella nova." J Biol Chem. 2006; 281(52): 40124-34., PMID: 17082188  
 Region 1Laporte L, Stultz J, Thomas GJ Jr. "Solution conformations and interactions of alpha and beta subunits of the Oxytricha nova telomere binding protein: investigation by Raman spectroscopy." Biochemistry. 1997; 36(26): 8053-8059., PMID: 9201953  
DP00661 Al-Ali H, Rieger ME, Seldeen KL, Harris TK, Farooq A, Briegel KJ. "Biophysical characterization reveals structural disorder in the developmental transcriptional regulator LBH." Biochem Biophys Res Commun. 2010; 391(1): 1104-9., PMID: 20005203  
 Region 1, Region 2Al-Ali H, Rieger ME, Seldeen KL, Harris TK, Farooq A, Briegel KJ. "Biophysical characterization reveals structural disorder in the developmental transcriptional regulator LBH." Biochem Biophys Res Commun. 2010; 391(1): 1104-9., PMID: 20005203  
DP00662Region 1Falk S, Ravaud S, Koch J, Sinning I. "The C Terminus of the Alb3 Membrane Insertase Recruits cpSRP43 to the Thylakoid Membrane." J Biol Chem. 2010; 285(8): 5954-62., PMID: 20018841  
DP00663 Majava V, Wang C, Myllykoski M, Kangas SM, Kang SU, Hayashi N, Baumgartel P, Heape AM, Lubec G, Kursula P. "Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule." Amino Acids. 2009., PMID: 19855925  
 Region 1Majava V, Wang C, Myllykoski M, Kangas SM, Kang SU, Hayashi N, Baumgartel P, Heape AM, Lubec G, Kursula P. "Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule." Amino Acids. 2009., PMID: 19855925  
DP00664 Shih MD, Hsieh TY, Lin TP, Hsing YI, Hoekstra FA. "Characterization of two soybean (Glycine max L.) LEA IV proteins by circular dichroism and Fourier transform infrared spectrometry." Plant Cell Physiol. ., PMID: 20071374  
 Region 1Shih MD, Hsieh TY, Lin TP, Hsing YI, Hoekstra FA. "Characterization of two soybean (Glycine max L.) LEA IV proteins by circular dichroism and Fourier transform infrared spectrometry." Plant Cell Physiol. ., PMID: 20071374  
DP00665 Shih MD, Hsieh TY, Lin TP, Hsing YI, Hoekstra FA. "Characterization of two soybean (Glycine max L.) LEA IV proteins by circular dichroism and Fourier transform infrared spectrometry." Plant Cell Physiol. ., PMID: 20071374  
 Region 1Shih MD, Hsieh TY, Lin TP, Hsing YI, Hoekstra FA. "Characterization of two soybean (Glycine max L.) LEA IV proteins by circular dichroism and Fourier transform infrared spectrometry." Plant Cell Physiol. ., PMID: 20071374  
DP00666Region 1Tyukhtenko S, Deshmukh L, Kumar V, Lary J, Cole J, Lemmon V, Vinogradova O. "Characterization of the neuron-specific L1-CAM cytoplasmic tail: naturally disordered in solution it exercises different binding modes for different adaptor proteins." Biochemistry. 2008; 47(13): 4160-4168., PMID: 18321067  
DP00667Region 1Kovacs D, Kalmar E, Torok Z, Tompa P. "Chaperone Activity of ERD10 and ERD14, Two Disordered Stress-Related Plant Proteins." Plant Physiol. : 381-390., PMID: 18359842  
DP00668 Yanagihara I, Nakahira K, Yamane T, Kaieda S, Mayanagi K, Hamada D, Fukui T, Ohnishi K, Kajiyama S, Shimizu T, Sato M, Ikegami T, Ikeguchi M, Honda T, Hashimoto H. "Structure and functional characterization of Vibrio parahaemolyticus thermostable direct hemolysin." J. Biol. Chem.. 2010; 285(21): 16267-74., PMID: 20335168  
 Region 1Yanagihara I, Nakahira K, Yamane T, Kaieda S, Mayanagi K, Hamada D, Fukui T, Ohnishi K, Kajiyama S, Shimizu T, Sato M, Ikegami T, Ikeguchi M, Honda T, Hashimoto H. "Structure and functional characterization of Vibrio parahaemolyticus thermostable direct hemolysin." J. Biol. Chem.. 2010; 285(21): 16267-74., PMID: 20335168  
DP00669 Jois PS, Manjunath P. "The N-terminal part of Binder of SPerm 5 (BSP5), which promotes sperm capacitation in bovine species is intrinsically disordered." Biochem. Biophys. Res. Commun.. 2010; 394(4): 1036-41., PMID: 20331968  
  Salois D, Menard M, Paquette Y, Manjunath P. "Complementary deoxyribonucleic acid cloning and tissue expression of BSP-A3 and BSP-30-kDa: phosphatidylcholine and heparin-binding proteins of bovine seminal plasma." Biol. Reprod.. 1999; 61(1): 288-97., PMID: 10377061  
 Region 1Jois PS, Manjunath P. "The N-terminal part of Binder of SPerm 5 (BSP5), which promotes sperm capacitation in bovine species is intrinsically disordered." Biochem. Biophys. Res. Commun.. 2010; 394(4): 1036-41., PMID: 20331968  
 Region 1Salois D, Menard M, Paquette Y, Manjunath P. "Complementary deoxyribonucleic acid cloning and tissue expression of BSP-A3 and BSP-30-kDa: phosphatidylcholine and heparin-binding proteins of bovine seminal plasma." Biol. Reprod.. 1999; 61(1): 288-97., PMID: 10377061  
DP00670 Huang Y, Liu Z. "Kinetic advantage of intrinsically disordered proteins in coupled folding-binding process: a critical assessment of the "fly-casting" mechanism." J Mol Biol. 2009; 393(5): 1143-1159., PMID: 19747922  
 Region 1Li P, Willie ST, Bauer S, Morris DL, Spies T, Strong RK. "Crystal structure of the MHC class I homolog MIC-A, a gammadelta T cell ligand." Immunity. 1999; 10(5): 577-584., PMID: 10367903  
DP00671 Tong KI, Katoh Y, Kusunoki H, Itoh K, Tanaka T, Yamamoto M. "Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model." Mol Cell Biol. 2006; 26(8): 2887-900., PMID: 16581765  
 Region 1Tong KI, Katoh Y, Kusunoki H, Itoh K, Tanaka T, Yamamoto M. "Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model." Mol Cell Biol. 2006; 26(8): 2887-900., PMID: 16581765  
DP00672Region 1Aguado-Llera D, Goormaghtigh E, de Geest N, Quan XJ, Prieto A, Hassan BA, Gomez J, Neira JL. "The basic helix-loop-helix region of human neurogenin 1 is a monomeric natively unfolded protein which forms a "fuzzy" complex upon DNA binding." Biochemistry. ., PMID: 20102160  
DP00673_C001Region 1, Region 2Ivanyi-Nagy R, Lavergne JP, Gabus C, Ficheux D, Darlix JL. "RNA chaperoning and intrinsic disorder in the core proteins of Flaviviridae." Nucleic Acids Res. 2008; 36(3): 712-725., PMID: 18033802  
DP00674_C001Region 1Ivanyi-Nagy R, Lavergne JP, Gabus C, Ficheux D, Darlix JL. "RNA chaperoning and intrinsic disorder in the core proteins of Flaviviridae." Nucleic Acids Res. 2008; 36(3): 712-725., PMID: 18033802  
DP00675_C002Region 1Ivanyi-Nagy R, Lavergne JP, Gabus C, Ficheux D, Darlix JL. "RNA chaperoning and intrinsic disorder in the core proteins of Flaviviridae." Nucleic Acids Res. 2008; 36(3): 712-725., PMID: 18033802  
DP00676Region 1Jaya N, Garcia V, Vierling E. "Substrate binding site flexibility of the small heat shock protein molecular chaperones." Proc Natl Acad Sci U S A. 2009; 106(37): 15604-9., PMID: 19717454  
DP00677 vanMontfort, Rob L. M., Eman Basha, Kenneth L. Friedrich, Christine Slingsby, Elizabeth Vierling. "Crystal structure and assembly of a eukaryotic small heat shock protein." 2001; 8: 1025-1030., PMID: 11702068  
 Region 1vanMontfort, Rob L. M., Eman Basha, Kenneth L. Friedrich, Christine Slingsby, Elizabeth Vierling. "Crystal structure and assembly of a eukaryotic small heat shock protein." 2001; 8: 1025-1030., PMID: 11702068  
DP00678Region 1Trevino MA, Rodriguez-Rodriguez M, Correas I, Marcilla M, Albar JP, Rico M, Jimenez MA, Bruix M. "NMR characterisation of the minimal interacting regions of centrosomal proteins 4.1R and NuMA1: effect of phosphorylation." BMC Biochem. ; 11(1): 7., PMID: 20109190  
DP00680 Felizmenio-Quimio ME, Daly NL, Craik DJ. "Circular proteins in plants: solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis." J Biol Chem. 2001; 276(25): 22875-82., PMID: 11292835  
  Heitz A, Hernandez JF, Gagnon J, Hong TT, Pham TT, Nguyen TM, Le-Nguyen D, Chiche L. "Solution structure of the squash trypsin inhibitor MCoTI-II. A new family for cyclic knottins." Biochemistry. 2001; 40(27): 7973-83., PMID: 11434766  
 Region 1, Region 2, Region 8, Region 9, Region 10, Region 11, Region 12Felizmenio-Quimio ME, Daly NL, Craik DJ. "Circular proteins in plants: solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis." J Biol Chem. 2001; 276(25): 22875-82., PMID: 11292835  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Heitz A, Hernandez JF, Gagnon J, Hong TT, Pham TT, Nguyen TM, Le-Nguyen D, Chiche L. "Solution structure of the squash trypsin inhibitor MCoTI-II. A new family for cyclic knottins." Biochemistry. 2001; 40(27): 7973-83., PMID: 11434766  
DP00681Region 1Chan LY, Wang CK, Major JM, Greenwood KP, Lewis RJ, Craik DJ, Daly NL. "Isolation and characterization of peptides from Momordica cochinchinensis seeds." J Nat Prod. 2009; 72(8): 1453-8., PMID: 19711988  
DP00682Region 1, Region 2, Region 3Radhakrishnan I, Perez-Alvarado GC, Parker D, Dyson HJ, Montminy MR, Wright PE. "Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions." Cell. 1997; 91(6): 741-752., PMID: 9413984  
DP00683 Ju JH, Maeng JS, Lee DY, Piszczek G, Gelmann EP, Gruschus JM. "Interactions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomain." Biochem J. 2009; 48(44): 10601-10607., PMID: 19780584  
 Region 1Ju JH, Maeng JS, Lee DY, Piszczek G, Gelmann EP, Gruschus JM. "Interactions of the acidic domain and SRF interacting motifs with the NKX3.1 homeodomain." Biochem J. 2009; 48(44): 10601-10607., PMID: 19780584  
DP00684 Manelytea, Laura, Colin P. Guyb, Rachel M. Smitha, Mark S. Dillinghama, Peter McGlynnb and Nigel J. Savery. "The unstructured C-terminal extension of UvrD interacts with UvrB, but is dispensable for nucleotide excision repair." DNA Repair (Amst). 2009; 8: 1300-1310., PMID: 19762288  
 Region 1Manelytea, Laura, Colin P. Guyb, Rachel M. Smitha, Mark S. Dillinghama, Peter McGlynnb and Nigel J. Savery. "The unstructured C-terminal extension of UvrD interacts with UvrB, but is dispensable for nucleotide excision repair." DNA Repair (Amst). 2009; 8: 1300-1310., PMID: 19762288  
 Region 1Lee, J.Y. and W. Yang. "UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke." Cell. 2006; 127(7): 1349–1360., PMID: 17190599  
DP00685 Liwang AC, Wang ZX, Sun Y, Peiper SC, Liwang PJ. "The solution structure of the anti-HIV chemokine vMIP-II." 1999; 8(11): 2270-80., PMID: 10595530  
 Region 1, Region 2Liwang AC, Wang ZX, Sun Y, Peiper SC, Liwang PJ. "The solution structure of the anti-HIV chemokine vMIP-II." 1999; 8(11): 2270-80., PMID: 10595530  
DP00686Region 1, Region 2Bowden TA, Crispin M, Harvey DJ, Aricescu AR, Grimes JM, Jones EY, Stuart DI. "Crystal structure and carbohydrate analysis of Nipah virus attachment glycoprotein: a template for antiviral and vaccine design." J Virol. 2008; 82(23): 11628-36., PMID: 18815311  
DP00687 Uversky VN, Oldfield CJ, Dunker AK. "Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling." J Mol Recognit. 2005; 18(5): 343-84., PMID: 16094605 kedunker@iupui.edu
 Region 1Nett JH, Hunte C, Trumpower BL. "Changes to the length of the flexible linker region of the Rieske protein impair the interaction of ubiquinol with the cytochrome bc1 complex." Eur J Biochem. 2000; 267(18): 5777-82., PMID: 10971589  
DP00688Region 1, Region 2, Region 3, Region 4Forbes JG, Flaherty DB, Ma K, Qadota H, Benian GM, Wang K. "Extensive and modular intrinsically disordered segments in C. elegans TTN-1 and implications in filament binding, elasticity and oblique striation." J Mol Biol. ., PMID: 20346955  
DP00689Region 1Mouillon JM, Gustafsson P, Harryson P. "Structural investigation of disordered stress proteins. Comparison of full-length dehydrins with isolated peptides of their conserved segments." Plant Physiol. 2006; 141: 638-650., PMID: 16565295  
DP00690Region 1Dhagat U, Endo S, Mamiya H, Hara A, El-Kabbani O. "Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme." Acta Crystallogr D Biol Crystallogr. 2010; 66(Pt 2): 198-204., PMID: 20124700  
DP00691 Renault L, Nassar N, Vetter I, Becker J, Klebe C, Roth M, Wittinghofer A. "The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller." Nature. 1998; 392(6671): 97-101., PMID: 9510255  
  England JR, Huang J, Jennings MJ, Makde RD, Tan S. "RCC1 uses a conformationally diverse loop region to interact with the nucleosome: a model for the RCC1-nucleosome complex." J. Mol. Biol.. 2010; 398(4): 518-29., PMID: 20347844  
  Renault L, Kuhlmann J, Henkel A, Wittinghofer A. "Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1)." Cell. 2001; 105(2): 245-55., PMID: 11336674  
 Region 1, Region 2England JR, Huang J, Jennings MJ, Makde RD, Tan S. "RCC1 uses a conformationally diverse loop region to interact with the nucleosome: a model for the RCC1-nucleosome complex." J. Mol. Biol.. 2010; 398(4): 518-29., PMID: 20347844  
 Region 3Renault L, Nassar N, Vetter I, Becker J, Klebe C, Roth M, Wittinghofer A. "The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller." Nature. 1998; 392(6671): 97-101., PMID: 9510255  
DP00692_A001 Shaw WJ, Ferris K, Tarasevich B, Larson JL. "The structure and orientation of the C-terminus of LRAP." Biophys. J.. 2008; 94(8): 3247-57., PMID: 18192371  
  Margolis HC, Beniash E, Fowler CE. "Role of macromolecular assembly of enamel matrix proteins in enamel formation." J. Dent. Res.. 2006; 85(9): 775-93., PMID: 16931858  
  Moradian-Oldak J. "Amelogenins: assembly, processing and control of crystal morphology." Matrix Biol.. 2001; 20(5-6): 293-305., PMID: 11566263  
  Shaw WJ, Campbell AA, Paine ML, Snead ML. "The COOH terminus of the amelogenin, LRAP, is oriented next to the hydroxyapatite surface." J. Biol. Chem.. 2004; 279(39): 40263-6., PMID: 15299015  
  Shaw WJ, Ferris K. "Structure, orientation, and dynamics of the C-terminal hexapeptide of LRAP determined using solid-state NMR." J Phys Chem B. 2008; 112(51): 16975-81., PMID: 19368031  
  Aoba T, Moreno EC. "The enamel fluid in the early secretory stage of porcine amelogenesis: chemical composition and saturation with respect to enamel mineral." Calcif. Tissue Int.. 1987; 41(2): 86-94., PMID: 3115550  
 Region 1, Region 2, Region 3, Region 4Buchko GW, Tarasevich BJ, Bekhazi J, Snead ML, Shaw WJ. "A solution NMR investigation into the early events of amelogenin nanosphere self-assembly initiated with sodium chloride or calcium chloride." Biochemistry. 2008; 47(50): 13215-22., PMID: 19086270  
 Region 1, Region 2, Region 3, Region 4Buchko GW, Bekhazi J, Cort JR, Valentine NB, Snead ML, Shaw WJ. "1H, 13C, and 15N resonance assignments of murine amelogenin, an enamel biomineralization protein." Biomol NMR Assign. 2008; 2(1): 89-91., PMID: 19081741  
DP00692_A002 Buchko GW, Tarasevich BJ, Roberts J, Snead ML, Shaw WJ. "A solution NMR investigation into the murine amelogenin splice-variant LRAP (Leucine-Rich Amelogenin Protein)." Biochim. Biophys. Acta. 2010; 1804(9): 1768-74., PMID: 20304108  
 Region 1, Region 2, Region 3, Region 4Buchko GW, Tarasevich BJ, Roberts J, Snead ML, Shaw WJ. "A solution NMR investigation into the murine amelogenin splice-variant LRAP (Leucine-Rich Amelogenin Protein)." Biochim. Biophys. Acta. 2010; 1804(9): 1768-74., PMID: 20304108  
DP00693 Delak K, Harcup C, Lakshminarayanan R, Sun Z, Fan Y, Moradian-Oldak J, Evans JS. "The tooth enamel protein, porcine amelogenin, is an intrinsically disordered protein with an extended molecular configuration in the monomeric form." Biochemistry. 2009; 48(10): 2272-81., PMID: 19236004  
  Lakshminarayanan R, Fan D, Du C, Moradian-Oldak J. "The role of secondary structure in the entropically driven amelogenin self-assembly." Biophys J. 2007; 93(10): 3664-74., PMID: 17704165  
  Moradian-Oldak J and Lakshminarayanan L. (Bentham Science Publishers, Ltd, e-book). "Intrinsic disorder in amelogenins." Amelogenins: Multifaceted Proteins For Dental And Bone Formation And Repair. 2010; 106-132. 
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10Delak K, Harcup C, Lakshminarayanan R, Sun Z, Fan Y, Moradian-Oldak J, Evans JS. "The tooth enamel protein, porcine amelogenin, is an intrinsically disordered protein with an extended molecular configuration in the monomeric form." Biochemistry. 2009; 48(10): 2272-81., PMID: 19236004  
DP00694 Neira JL, Román-Trufero M, Contreras LM, Prieto J, Singh G, Barrera FN, Renart ML, Vidal M. "The transcriptional repressor RYBP is a natively unfolded protein which folds upon binding to DNA." Biochemistry. 2009; 48(6): 1348-60., PMID: 19170609  
 Region 1Neira JL, Román-Trufero M, Contreras LM, Prieto J, Singh G, Barrera FN, Renart ML, Vidal M. "The transcriptional repressor RYBP is a natively unfolded protein which folds upon binding to DNA." Biochemistry. 2009; 48(6): 1348-60., PMID: 19170609  
DP00695 Gupta,Vibha, Rakesh K. Gupta, Garima Khare, Dinakar M. Salunke, Avadhesha Surolia, and Anil K. Tyagi. "Structural Ordering of Disordered Ligand-Binding Loops of Biotin Protein Ligase into Active Conformations as a Consequence of Dehydration." PLoS One. 2010; 5(2)., PMID: 20169168  
 Region 1, Region 2Gupta,Vibha, Rakesh K. Gupta, Garima Khare, Dinakar M. Salunke, Avadhesha Surolia, and Anil K. Tyagi. "Structural Ordering of Disordered Ligand-Binding Loops of Biotin Protein Ligase into Active Conformations as a Consequence of Dehydration." PLoS One. 2010; 5(2)., PMID: 20169168  
DP00696Region 1Ye J, Mayer KL, Mayer MR, Stone MJ. "NMR solution structure and backbone dynamics of the CC chemokine eotaxin-3." Biochemistry. 2001; 40(26): 7820-7831., PMID: 11425309  
DP00697 Habchi J, Mamelli L, Darbon H, Longhi S. "Structural disorder within Henipavirus nucleoprotein and phosphoprotein: from predictions to experimental assessment." PLoS ONE. 2010; 5(7): e11684., PMID: 20657787  
 Region 1Habchi J, Mamelli L, Darbon H, Longhi S. "Structural disorder within Henipavirus nucleoprotein and phosphoprotein: from predictions to experimental assessment." PLoS ONE. 2010; 5(7): e11684., PMID: 20657787  
DP00698 Habchi J, Mamelli L, Darbon H, Longhi S. "Structural disorder within Henipavirus nucleoprotein and phosphoprotein: from predictions to experimental assessment." PLoS ONE. 2010; 5(7): e11684., PMID: 20657787  
 Region 1Habchi J, Mamelli L, Darbon H, Longhi S. "Structural disorder within Henipavirus nucleoprotein and phosphoprotein: from predictions to experimental assessment." PLoS ONE. 2010; 5(7): e11684., PMID: 20657787  
DP00699 Habchi J, Mamelli L, Darbon H, Longhi S. "Structural disorder within Henipavirus nucleoprotein and phosphoprotein: from predictions to experimental assessment." PLoS ONE. 2010; 5(7): e11684., PMID: 20657787  
 Region 1Habchi J, Mamelli L, Darbon H, Longhi S. "Structural disorder within Henipavirus nucleoprotein and phosphoprotein: from predictions to experimental assessment." PLoS ONE. 2010; 5(7): e11684., PMID: 20657787  
DP00700 Habchi J, Mamelli L, Darbon H, Longhi S. "Structural disorder within Henipavirus nucleoprotein and phosphoprotein: from predictions to experimental assessment." PLoS ONE. 2010; 5(7): e11684., PMID: 20657787  
 Region 1Habchi J, Mamelli L, Darbon H, Longhi S. "Structural disorder within Henipavirus nucleoprotein and phosphoprotein: from predictions to experimental assessment." PLoS ONE. 2010; 5(7): e11684., PMID: 20657787  
DP00701 Molloy RG, Ma WK, Allen AC, Greenwood K, Bryan L, Sacora R, Williams L, Gage MJ. "Aquifex aeolicus FlgM protein exhibits a temperature-dependent disordered nature." Biochim. Biophys. Acta. 2010; 1804(7): 1457-66., PMID: 20298817  
  Sorenson MK, Ray SS, Darst SA. "Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation." Mol. Cell. 2004; 14(1): 127-38., PMID: 15068809  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Sorenson MK, Ray SS, Darst SA. "Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation." Mol. Cell. 2004; 14(1): 127-38., PMID: 15068809  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Molloy RG, Ma WK, Allen AC, Greenwood K, Bryan L, Sacora R, Williams L, Gage MJ. "Aquifex aeolicus FlgM protein exhibits a temperature-dependent disordered nature." Biochim. Biophys. Acta. 2010; 1804(7): 1457-66., PMID: 20298817  
DP00702Region 2, Region 3, Region 4Li Z, Zhao B, Wang P, Chen F, Dong Z, Yang H, Guan KL, Xu Y. "Structural insights into the YAP and TEAD complex." Genes Dev.. 2010; 24(3): 235-40., PMID: 20123905  
 Region 1Tian W, Yu J, Tomchick DR, Pan D, Luo X. "Structural and functional analysis of the YAP-binding domain of human TEAD2." Proc. Natl. Acad. Sci. U.S.A.. 2010; 107(16): 7293-8., PMID: 20368466  
DP00703 Bick MJ, Banik JJ, Darst SA, Brady SF. "Crystal structures of the glycopeptide sulfotransferase Teg12 in a complex with the teicoplanin aglycone." Biochemistry. 2010; 49(19): 4159-68., PMID: 20361791  
 Region 1, Region 2, Region 3, Region 4, Region 5Bick MJ, Banik JJ, Darst SA, Brady SF. "Crystal structures of the glycopeptide sulfotransferase Teg12 in a complex with the teicoplanin aglycone." Biochemistry. 2010; 49(19): 4159-68., PMID: 20361791  
DP00704 Sanchez R, Pantoja-Uceda D, Prieto J, Diercks T, Marcaida MJ, Montoya G, Campos-Olivas R, Blanco FJ. "Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase." J. Biol. Chem.. 2010; 285(29): 22196-201., PMID: 20460379  
 Region 1, Region 2, Region 3Sanchez R, Pantoja-Uceda D, Prieto J, Diercks T, Marcaida MJ, Montoya G, Campos-Olivas R, Blanco FJ. "Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase." J. Biol. Chem.. 2010; 285(29): 22196-201., PMID: 20460379  
DP00705 Welker S, Rudolph B, Frenzel E, Hagn F, Liebisch G, Schmitz G, Scheuring J, Kerth A, Blume A, Weinkauf S, Haslbeck M, Kessler H, Buchner J. "Hsp12 is an intrinsically unstructured stress protein that folds upon membrane association and modulates membrane function." Mol. Cell. 2010; 39(4): 507-20., PMID: 20797624  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Welker S, Rudolph B, Frenzel E, Hagn F, Liebisch G, Schmitz G, Scheuring J, Kerth A, Blume A, Weinkauf S, Haslbeck M, Kessler H, Buchner J. "Hsp12 is an intrinsically unstructured stress protein that folds upon membrane association and modulates membrane function." Mol. Cell. 2010; 39(4): 507-20., PMID: 20797624  
DP00706 Caubet C, Bousset L, Clemmensen O, Sourigues Y, Bygum A, Chavanas S, Coudane F, Hsu CY, Betz RC, Melki R, Simon M, Serre G. "A new amyloidosis caused by fibrillar aggregates of mutated corneodesmosin." FASEB J.. 2010; 24(9): 3416-26., PMID: 20448140  
 Region 1Caubet C, Bousset L, Clemmensen O, Sourigues Y, Bygum A, Chavanas S, Coudane F, Hsu CY, Betz RC, Melki R, Simon M, Serre G. "A new amyloidosis caused by fibrillar aggregates of mutated corneodesmosin." FASEB J.. 2010; 24(9): 3416-26., PMID: 20448140  
DP00707 Escobar-Cabrera E, Lau DK, Giovinazzi S, Ishov AM, McIntosh LP. "Structural characterization of the DAXX N-terminal helical bundle domain and its complex with Rassf1C." Structure. 2010; 18(12): 1642-53., PMID: 21134643  
 Region 1, Region 2Escobar-Cabrera E, Lau DK, Giovinazzi S, Ishov AM, McIntosh LP. "Structural characterization of the DAXX N-terminal helical bundle domain and its complex with Rassf1C." Structure. 2010; 18(12): 1642-53., PMID: 21134643  
 Region 1Santiago A, Godsey AC, Hossain J, Zhao LY, Liao D. "Identification of two independent SUMO-interacting motifs in Daxx: evolutionary conservation from Drosophila to humans and their biochemical functions." Cell Cycle. 2009; 8(1): 76-87., PMID: 19106612  
 Region 1Lin DY, Huang YS, Jeng JC, Kuo HY, Chang CC, Chao TT, Ho CC, Chen YC, Lin TP, Fang HI, Hung CC, Suen CS, Hwang MJ, Chang KS, Maul GG, Shih HM. "Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors." Mol. Cell. 2006; 24(3): 341-54., PMID: 17081986  
DP00708 Escobar-Cabrera E, Lau DK, Giovinazzi S, Ishov AM, McIntosh LP. "Structural characterization of the DAXX N-terminal helical bundle domain and its complex with Rassf1C." Structure. 2010; 18(12): 1642-53., PMID: 21134643  
 Region 1Escobar-Cabrera E, Lau DK, Giovinazzi S, Ishov AM, McIntosh LP. "Structural characterization of the DAXX N-terminal helical bundle domain and its complex with Rassf1C." Structure. 2010; 18(12): 1642-53., PMID: 21134643  
 Region 1Santiago A, Godsey AC, Hossain J, Zhao LY, Liao D. "Identification of two independent SUMO-interacting motifs in Daxx: evolutionary conservation from Drosophila to humans and their biochemical functions." Cell Cycle. 2009; 8(1): 76-87., PMID: 19106612  
 Region 1Lin DY, Huang YS, Jeng JC, Kuo HY, Chang CC, Chao TT, Ho CC, Chen YC, Lin TP, Fang HI, Hung CC, Suen CS, Hwang MJ, Chang KS, Maul GG, Shih HM. "Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors." Mol. Cell. 2006; 24(3): 341-54., PMID: 17081986  
DP00709 Mokhtarzada S, Yu C, Brickenden A, Choy WY. "Structural Characterization of Partially Disordered Human Chibby: Insights into Its Function in the Wnt-Signaling Pathway." 2011., PMID: 21182262  
 Region 1, Region 2, Region 3, Region 4Mokhtarzada S, Yu C, Brickenden A, Choy WY. "Structural Characterization of Partially Disordered Human Chibby: Insights into Its Function in the Wnt-Signaling Pathway." 2011., PMID: 21182262  
DP00710 Feige MJ, Groscurth S, Marcinowski M, Shimizu Y, Kessler H, Hendershot LM, Buchner J. "An unfolded CH1 domain controls the assembly and secretion of IgG antibodies." Mol. Cell. 2009; 34(5): 569-79., PMID: 19524537  
  Augustine JG, de La Calle A, Knarr G, Buchner J, Frederick CA. "The crystal structure of the Fab fragment of the monoclonal antibody MAK33. Implications for folding and interaction with the chaperone BiP." J. Biol. Chem.. 2000; 276(5): 3287-94., PMID: 11036070  
 Region 1Feige MJ, Groscurth S, Marcinowski M, Shimizu Y, Kessler H, Hendershot LM, Buchner J. "An unfolded CH1 domain controls the assembly and secretion of IgG antibodies." Mol. Cell. 2009; 34(5): 569-79., PMID: 19524537  
 Region 1Augustine JG, de La Calle A, Knarr G, Buchner J, Frederick CA. "The crystal structure of the Fab fragment of the monoclonal antibody MAK33. Implications for folding and interaction with the chaperone BiP." J. Biol. Chem.. 2000; 276(5): 3287-94., PMID: 11036070  
DP00711Region 1, Region 2, Region 3Tanabe, W, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S. "Solution structure of the ARID domain of Jarid1b protein. Primary reference of PDB structure 2EQY: Solution structure of the ARID domain of Jarid1b protein. RIKEN Structural Genomics/Proteomics Initiative. PDB citation." 2007. 
DP00712Region 1, Region 2, Region 3Yao W, Peng Y, Chen Q, Lin D. "1H, 13C, 15N backbone and side-chain resonance assignments of the Bright/ARID domain from the human histone demethylase JARID1B." Biomol NMR Assign. 2009; 3(1): 85-7., PMID: 19636953  
 Region 1, Region 2, Region 3Yao W, Peng Y, Lin D. "The flexible loop L1 of the H3K4 demethylase JARID1B ARID domain has a crucial role in DNA-binding activity." Biochem. Biophys. Res. Commun.. 2010; 396(2): 323-8., PMID: 20403335  
DP00713Region 3Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H, Luo JL, Patel DJ, Allis CD. "Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger." Nature. 2009; 459(7248): 847-51., PMID: 19430464  
 Region 1, Region 2Tu S, Teng YC, Yuan C, Wu YT, Chan MY, Cheng AN, Lin PH, Juan LJ, Tsai MD. "The ARID domain of the H3K4 demethylase RBP2 binds to a DNA CCGCCC motif." Nat. Struct. Mol. Biol.. 2008; 15(4): 419-21., PMID: 18270511  
DP00714 Michenfelder M, Fu G, Lawrence C, Weaver JC, Wustman BA, Taranto L, Evans JS, Morse DE. "Characterization of two molluscan crystal-modulating biomineralization proteins and identification of putative mineral binding domains." Biopolymers. 2003; 70(4): 522-33., PMID: 14648763  
  Fu, G., S.R. Qiu, C.A. Orme, D.E. Morse, and J.J. DeYoreo. "Acceleration of Calcite Kinetics by Abalone Nacre Proteins (+cover)." Advanced Materials. 2005; 17(22): 2678-2683. 
  Kim IW, Collino S, Morse DE, Evans JS. [http://pubs.acs.org/doi/abs/10.1021/cg060056q]. "A Crystal Modulating Protein from Molluscan Nacre That Limits the Growth of Calcite in Vitro." ACS Crystal Growth & Design. 2006; 6(5): 1078-1082. 
  Fu G, Valiyaveettil S, Wopenka B, Morse DE. "CaCO3 biomineralization: acidic 8-kDa proteins isolated from aragonitic abalone shell nacre can specifically modify calcite crystal morphology." Biomacromolecules. 2006; 6(3): 1289-98., PMID: 15877344  
  Collino S, Kim IW, Evans JS. "Identification and structural characterization of an unusual RING-like sequence within an extracellular biomineralization protein, AP7." Biochemistry. 2008; 47(12): 3745-55., PMID: 18298090  
  Wustman BA, Morse DE, Evans JS. "Structural characterization of the N-terminal mineral modification domains from the molluscan crystal-modulating biomineralization proteins, AP7 and AP24." Biopolymers. 2004; 74(5): 363-76., PMID: 15222016  
  Amos FF, Evans JS. "AP7, a partially disordered pseudo C-RING protein, is capable of forming stabilized aragonite in vitro." Biochemistry. 2009; 48(6): 1332-9., PMID: 19159266  
 Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8Kim IW, Collino S, Morse DE, Evans JS. [http://pubs.acs.org/doi/abs/10.1021/cg060056q]. "A Crystal Modulating Protein from Molluscan Nacre That Limits the Growth of Calcite in Vitro." ACS Crystal Growth & Design. 2006; 6(5): 1078-1082. 
 Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8Amos FF, Evans JS. "AP7, a partially disordered pseudo C-RING protein, is capable of forming stabilized aragonite in vitro." Biochemistry. 2009; 48(6): 1332-9., PMID: 19159266  
 Region 2Wustman BA, Morse DE, Evans JS. "Structural characterization of the N-terminal mineral modification domains from the molluscan crystal-modulating biomineralization proteins, AP7 and AP24." Biopolymers. 2004; 74(5): 363-76., PMID: 15222016  
 Region 1, Region 2Michenfelder M, Fu G, Lawrence C, Weaver JC, Wustman BA, Taranto L, Evans JS, Morse DE. "Characterization of two molluscan crystal-modulating biomineralization proteins and identification of putative mineral binding domains." Biopolymers. 2003; 70(4): 522-33., PMID: 14648763  
 Region 3, Region 4, Region 5, Region 6, Region 7, Region 8Collino S, Kim IW, Evans JS. "Identification and structural characterization of an unusual RING-like sequence within an extracellular biomineralization protein, AP7." Biochemistry. 2008; 47(12): 3745-55., PMID: 18298090  
DP00715 Wustman BA, Morse DE, Evans JS. "Structural characterization of the N-terminal mineral modification domains from the molluscan crystal-modulating biomineralization proteins, AP7 and AP24." Biopolymers. 2004; 74(5): 363-76., PMID: 15222016  
  Michenfelder M, Fu G, Lawrence C, Weaver JC, Wustman BA, Taranto L, Evans JS, Morse DE. "Characterization of two molluscan crystal-modulating biomineralization proteins and identification of putative mineral binding domains." Biopolymers. 2003; 70(4): 522-33., PMID: 14648763  
 Region 2Wustman BA, Morse DE, Evans JS. "Structural characterization of the N-terminal mineral modification domains from the molluscan crystal-modulating biomineralization proteins, AP7 and AP24." Biopolymers. 2004; 74(5): 363-76., PMID: 15222016  
 Region 1, Region 2Michenfelder M, Fu G, Lawrence C, Weaver JC, Wustman BA, Taranto L, Evans JS, Morse DE. "Characterization of two molluscan crystal-modulating biomineralization proteins and identification of putative mineral binding domains." Biopolymers. 2003; 70(4): 522-33., PMID: 14648763  
DP00716_C001 Krimm I, Ostlund C, Gilquin B, Couprie J, Hossenlopp P, Mornon JP, Bonne G, Courvalin JC, Worman HJ, Zinn-Justin S. "The Ig-like structure of the C-terminal domain of lamin A/C, mutated in muscular dystrophies, cardiomyopathy, and partial lipodystrophy." Structure. 2002; 10(6): 811-23., PMID: 12057196  
  Dhe-Paganon S, Werner ED, Chi YI, Shoelson SE. "Structure of the globular tail of nuclear lamin." J. Biol. Chem.. 2002; 277(20): 17381-4., PMID: 11901143  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10, Region 11, Region 12, Region 13, Region 14, Region 15, Region 16, Region 17, Region 18, Region 19Krimm I, Ostlund C, Gilquin B, Couprie J, Hossenlopp P, Mornon JP, Bonne G, Courvalin JC, Worman HJ, Zinn-Justin S. "The Ig-like structure of the C-terminal domain of lamin A/C, mutated in muscular dystrophies, cardiomyopathy, and partial lipodystrophy." Structure. 2002; 10(6): 811-23., PMID: 12057196  
DP00717 Schedlbauer A, Gandini R, Kontaxis G, Paulmichl M, Furst J, Konrat R. "The C-terminus of ICln is Natively Disordered but Displays Local Structural Preformation." Cell. Physiol. Biochem.. 2011; 28(6): 1203-10., PMID: 22179008  
  Fürst J, Schedlbauer A, Gandini R, Garavaglia ML, Saino S, Gschwentner M, Sarg B, Lindner H, Jakab M, Ritter M, Bazzini C, Botta G, Meyer G, Kontaxis G, Tilly BC, Konrat R, Paulmichl M. "ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor LSm4." J. Biol. Chem.. 2005; 280(35): 31276-82., PMID: 15905169  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10, Region 11, Region 12, Region 13, Region 14, Region 15, Region 16, Region 17, Region 18Fürst J, Schedlbauer A, Gandini R, Garavaglia ML, Saino S, Gschwentner M, Sarg B, Lindner H, Jakab M, Ritter M, Bazzini C, Botta G, Meyer G, Kontaxis G, Tilly BC, Konrat R, Paulmichl M. "ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor LSm4." J. Biol. Chem.. 2005; 280(35): 31276-82., PMID: 15905169  
 Region 17, Region 18, Region 19, Region 20, Region 21, Region 22Schedlbauer A, Gandini R, Kontaxis G, Paulmichl M, Furst J, Konrat R. "The C-terminus of ICln is Natively Disordered but Displays Local Structural Preformation." Cell. Physiol. Biochem.. 2011; 28(6): 1203-10., PMID: 22179008  
DP00718_A001 Chandra V, Huang P, Hamuro Y, Raghuram S, Wang Y, Burris TP, Rastinejad F. "Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA." Nature. 2008; 456(7220): 350-6., PMID: 19043829  
 Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8, Region 9, Region 10Chandra V, Huang P, Hamuro Y, Raghuram S, Wang Y, Burris TP, Rastinejad F. "Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA." Nature. 2008; 456(7220): 350-6., PMID: 19043829  
 Region 2Fuxreiter M, Simon I, Bondos S. "Dynamic protein-DNA recognition: beyond what can be seen." Trends Biochem. Sci.. 2011; 36(8): 415-23., PMID: 21620710  
DP00719Region 1, Region 2, Region 3, Region 4Smet-Nocca C, Wieruszeski JM, Chaar V, Leroy A, Benecke A. "The thymine-DNA glycosylase regulatory domain: residual structure and DNA binding." Biochemistry. 2008; 47(25): 6519-30., PMID: 18512959  
 Region 3Maiti A, Morgan MT, Pozharski E, Drohat AC. "Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition." Proc. Natl. Acad. Sci. U.S.A.. 2008; 105(26): 8890-5., PMID: 18587051  
 Region 4Fuxreiter M, Simon I, Bondos S. "Dynamic protein-DNA recognition: beyond what can be seen." Trends Biochem. Sci.. 2011; 36(8): 415-23., PMID: 21620710  
 Region 3Baba D, Maita N, Jee JG, Uchimura Y, Saitoh H, Sugasawa K, Hanaoka F, Tochio H, Hiroaki H, Shirakawa M. "Crystal structure of thymine DNA glycosylase conjugated to SUMO-1." Nature. 2005; 435(7044): 979-82., PMID: 15959518  
 Region 3Baba D, Maita N, Jee JG, Uchimura Y, Saitoh H, Sugasawa K, Hanaoka F, Tochio H, Hiroaki H, Shirakawa M. "Crystal structure of SUMO-3-modified thymine-DNA glycosylase." J. Mol. Biol.. 2006; 359(1): 137-47., PMID: 16626738  
DP00720 Fuxreiter M, Simon I, Bondos S. "Dynamic protein-DNA recognition: beyond what can be seen." Trends Biochem. Sci.. 2011; 36(8): 415-23., PMID: 21620710  
 Region 4Kasai N, Tsunaka Y, Ohki I, Hirose S, Morikawa K, Tate S. "Solution structure of the HMG-box domain in the SSRP1 subunit of FACT." J. Biomol. NMR. 2005; 32(1): 83-8., PMID: 16041486  
 Region 1, Region 2, Region 3, Region 4, Region 5Tsunaka Y, Toga J, Yamaguchi H, Tate S, Hirose S, Morikawa K. "Phosphorylated intrinsically disordered region of FACT masks its nucleosomal DNA binding elements." J. Biol. Chem.. 2009; 284(36): 24610-21., PMID: 19605348  
 Region 1, Region 2, Region 3, Region 4, Region 5Miyagi A, Tsunaka Y, Uchihashi T, Mayanagi K, Hirose S, Morikawa K, Ando T. "Visualization of intrinsically disordered regions of proteins by high-speed atomic force microscopy." Chemphyschem. 2008; 9(13): 1859-66., PMID: 18698566  
DP00721Region 1Tsunaka Y, Toga J, Yamaguchi H, Tate S, Hirose S, Morikawa K. "Phosphorylated intrinsically disordered region of FACT masks its nucleosomal DNA binding elements." J. Biol. Chem.. 2009; 284(36): 24610-21., PMID: 19605348  
 Region 1Miyagi A, Tsunaka Y, Uchihashi T, Mayanagi K, Hirose S, Morikawa K, Ando T. "Visualization of intrinsically disordered regions of proteins by high-speed atomic force microscopy." Chemphyschem. 2008; 9(13): 1859-66., PMID: 18698566  
DP00722Region 1, Region 2Savvides SN, Raghunathan S, Futterer K, Kozlov AG, Lohman TM, Waksman G. "The C-terminal domain of full-length E. coli SSB is disordered even when bound to DNA." Protein Sci. 2004; 13(7): 1942-7., PMID: 15169953  
 Region 2Kozlov AG, Cox MM, Lohman TM. "Regulation of single-stranded DNA binding by the C termini of Escherichia coli single-stranded DNA-binding (SSB) protein." J. Biol. Chem.. 2010; 285(22): 17246-52., PMID: 20360609  
 Region 2Fuxreiter M, Simon I, Bondos S. "Dynamic protein-DNA recognition: beyond what can be seen." Trends Biochem. Sci.. 2011; 36(8): 415-23., PMID: 21620710  
DP00723 Murase K, Hirano Y, Sun TP, Hakoshima T. "Gibberellin-induced DELLA recognition by the gibberellin receptor GID1." Nature. 2008; 456(7221): 459-63., PMID: 19037309  
 Region 1Murase K, Hirano Y, Sun TP, Hakoshima T. "Gibberellin-induced DELLA recognition by the gibberellin receptor GID1." Nature. 2008; 456(7221): 459-63., PMID: 19037309  
DP00724 Murase K, Hirano Y, Sun TP, Hakoshima T. "Gibberellin-induced DELLA recognition by the gibberellin receptor GID1." Nature. 2008; 456(7221): 459-63., PMID: 19037309  
  Sun X, Jones WT, Rikkerink EH. "GRAS proteins: the versatile roles of intrinsically disordered proteins in plant signalling." Biochem. J.. 2012; 442(1): 1-12., PMID: 22280012  
 Region 1Murase K, Hirano Y, Sun TP, Hakoshima T. "Gibberellin-induced DELLA recognition by the gibberellin receptor GID1." Nature. 2008; 456(7221): 459-63., PMID: 19037309  
DP00725Region 1, Region 2Abendroth J, Rice AE, McLuskey K, Bagdasarian M, Hol WG. "The crystal structure of the periplasmic domain of the type II secretion system protein EpsM from Vibrio cholerae: the simplest version of the ferredoxin fold." J. Mol. Biol.. 2004; 338(3): 585-96., PMID: 15081815  
DP00726Region 1, Region 2, Region 3Abergel C, Rudinger-Thirion J, Giegé R, Claverie JM. "Virus-encoded aminoacyl-tRNA synthetases: structural and functional characterization of mimivirus TyrRS and MetRS." J. Virol.. 2007; 81(22): 12406-17., PMID: 17855524  
DP00727 Calamini B, Santarsiero BD, Boutin JA, Mesecar AD. "Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2." Biochem. J.. 2008; 413(1): 81-91., PMID: 18254726  
  Fu Y, Buryanovskyy L, Zhang Z. "Crystal structure of quinone reductase 2 in complex with cancer prodrug CB1954." Biochem. Biophys. Res. Commun.. 2005; 336(1): 332-8., PMID: 16129418  
 Region 1, Region 2, Region 3AbuKhader M, Heap J, De Matteis C, Kellam B, Doughty SW, Minton N, Paoli M. "Binding of the anticancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal structure of their complex." J. Med. Chem.. 2005; 48(24): 7714-9., PMID: 16302811  
DP00728Region 1, Region 2, Region 3, Region 4Walter J, Steigemann W, Singh TP, Bartunik H, Bode W, Huber R. "On the Disordered Activation Domain in Trypsinogen. Chemical Labelling and Low-Temperature Crystallography." Acta Crystallographica, Section B. 1982; 38(5): 1462–1472. 
DP00729Region 1, Region 2, Region 3, Region 4Addlagatta A, Krzywda S, Czapinska H, Otlewski J, Jaskolski M. "Ultrahigh-resolution structure of a BPTI mutant." Acta Crystallogr. D Biol. Crystallogr.. 2001; 57(Pt 5): 649-63., PMID: 11320305  
DP00730Region 1, Region 2, Region 3Ahmed FR, Rose DR, Evans SV, Pippy ME, To R. "Refinement of recombinant oncomodulin at 1.30 A resolution." J. Mol. Biol.. 1993; 230(4): 1216-24., PMID: 8487302  
 Region 4, Region 5Henzl MT, Tanner JJ. "Solution structure of Ca2+-free rat beta-parvalbumin (oncomodulin)." Protein Sci.. 2007; 16(9): 1914-26., PMID: 17766386  
DP00731Region 1Adman ET, Le Trong I, Stenkamp RE, Nieslanik BS, Dietze EC, Tai G, Ibarra C, Atkins WM. "Localization of the C-terminus of rat glutathione S-transferase A1-1: crystal structure of mutants W21F and W21F/F220Y." Proteins. 2001; 42(2): 192-200., PMID: 11119643  
DP00732_C001Region 1, Region 2Agarwal R, Eswaramoorthy S, Kumaran D, Binz T, Swaminathan S. "Structural analysis of botulinum neurotoxin type E catalytic domain and its mutant Glu212-->Gln reveals the pivotal role of the Glu212 carboxylate in the catalytic pathway." Biochemistry. 2004; 43(21): 6637-44., PMID: 15157097  
DP00733_C004Region 7Ahn VE, Leyko P, Alattia JR, Chen L, Privé GG. "Crystal structures of saposins A and C." Protein Sci.. 2006; 15(8): 1849-57., PMID: 16823039  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Hawkins CA, de Alba E, Tjandra N. "Solution structure of human saposin C in a detergent environment." J. Mol. Biol.. 2005; 346(5): 1381-92., PMID: 15713488  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6de Alba E, Weiler S, Tjandra N. "Solution structure of human saposin C: pH-dependent interaction with phospholipid vesicles." Biochemistry. 2003; 42(50): 14729-40., PMID: 14674747  
 Region 7Rossmann M, Schultz-Heienbrok R, Behlke J, Remmel N, Alings C, Sandhoff K, Saenger W, Maier T. "Crystal structures of human saposins C andD: implications for lipid recognition and membrane interactions." Structure. 2008; 16(5): 809-17., PMID: 18462685  
DP00734Region 1, Region 2, Region 3Huang N, Chelliah Y, Shan Y, Taylor CA, Yoo SH, Partch C, Green CB, Zhang H, Takahashi JS. "Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex." Science. 2012; 337(6091): 189-94., PMID: 22653727  
DP00735_A004Region 1, Region 2, Region 3, Region 4, Region 5Huang N, Chelliah Y, Shan Y, Taylor CA, Yoo SH, Partch C, Green CB, Zhang H, Takahashi JS. "Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex." Science. 2012; 337(6091): 189-94., PMID: 22653727  
DP00736Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7Schirle NT, MacRae IJ. "The crystal structure of human Argonaute2." Science. 2012; 336(6084): 1037-40., PMID: 22539551  
DP00738Region 1Akita M, Suzuki A, Kobayashi T, Ito S, Yamane T. "The first structure of pectate lyase belonging to polysaccharide lyase family 3." Acta Crystallogr. D Biol. Crystallogr.. 2001; 57(Pt 12): 1786-92., PMID: 11717490  
DP00741Region 1, Region 2, Region 3Ohlendorf DH, Tronrud DE, Matthews BW. "Refined structure of Cro repressor protein from bacteriophage lambda suggests both flexibility and plasticity." J. Mol. Biol.. 1998; 280(1): 129-36., PMID: 9653036  
 Region 1, Region 2, Region 3Matsuo H, Shirakawa M, Kyogoku Y. "Three-dimensional dimer structure of the lambda-Cro repressor in solution as determined by heteronuclear multidimensional NMR." J. Mol. Biol.. 1995; 254(4): 668-80., PMID: 7500341  
 Region 1, Region 2, Region 3Albright RA, Matthews BW. "Crystal structure of lambda-Cro bound to a consensus operator at 3.0 A resolution." J. Mol. Biol.. 1998; 280(1): 137-51., PMID: 9653037  
 Region 1, Region 2, Region 3Anderson WF, Ohlendorf DH, Takeda Y, Matthews BW. "Structure of the cro repressor from bacteriophage lambda and its interaction with DNA." Nature. 1981; 290(5809): 754-8., PMID: 6452580  
 Region 1, Region 2, Region 3Brennan RG, Roderick SL, Takeda Y, Matthews BW. "Protein-DNA conformational changes in the crystal structure of a lambda Cro-operator complex." Proc. Natl. Acad. Sci. U.S.A.. 1990; 87(20): 8165-9., PMID: 2146682  
DP00742Region 1, Region 2, Region 3, Region 4MacDonald JA, Ishida H, Butler EI, Ulke-Lemée A, Chappellaz M, Tulk SE, Chik JK, Vogel HJ. "Intrinsically disordered N-terminus of calponin homology-associated smooth muscle protein (CHASM) interacts with the calponin homology domain to enable tropomyosin binding." Biochemistry. 2012; 51(13): 2694-705., PMID: 22424482  
 Region 3, Region 4Ishida H, Borman MA, Ostrander J, Vogel HJ, MacDonald JA. "Solution structure of the calponin homology (CH) domain from the smoothelin-like 1 protein: a unique apocalmodulin-binding mode and the possible role of the C-terminal type-2 CH-domain in smooth muscle relaxation." J. Biol. Chem.. 2008; 283(29): 20569-78., PMID: 18477568  
 Region 1Wooldridge AA, Fortner CN, Lontay B, Akimoto T, Neppl RL, Facemire C, Datto MB, Kwon A, McCook E, Li P, Wang S, Thresher RJ, Miller SE, Perriard JC, Gavin TP, Hickner RC, Coffman TM, Somlyo AV, Yan Z, Haystead TA. "Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle." J. Biol. Chem.. 2008; 283(17): 11850-9., PMID: 18310078  
DP00743Region 1Thalhammer A, Hundertmark M, Popova AV, Seckler R, Hincha DK. "Interaction of two intrinsically disordered plant stress proteins (COR15A and COR15B) with lipid membranes in the dry state." Biochim. Biophys. Acta. 2010; 1798(9): 1812-20., PMID: 20510170  
DP00744Region 1, Region 2Wernimont, A.K., Dong, A., Choe, J., Gao, M., Walker, J., Lew, J., Alam, Z., Zhao, Y., Nordlund, P., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Artz, J.D. "Plasmodium yoelii Ribonucleotide Reductase Subunit R2 (PY03671) [XRay structure]." PDB Primary Citation. 2007. 
DP00745Region 1Vedadi M, Lew J, Artz J, Amani M, Zhao Y, Dong A, Wasney GA, Gao M, Hills T, Brokx S, Qiu W, Sharma S, Diassiti A, Alam Z, Melone M, Mulichak A, Wernimont A, Bray J, Loppnau P, Plotnikova O, Newberry K, Sundararajan E, Houston S, Walker J, Tempel W, Bochkarev A, Kozieradzki I, Edwards A, Arrowsmith C, Roos D, Kain K, Hui R. "Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms." Mol. Biochem. Parasitol.. 2006; 151(1): 100-10., PMID: 17125854  
DP00746 Klein MM, Gittis AG, Su HP, Makobongo MO, Moore JM, Singh S, Miller LH, Garboczi DN. "The cysteine-rich interdomain region from the highly variable plasmodium falciparum erythrocyte membrane protein-1 exhibits a conserved structure." PLoS Pathog.. 2008; 4(9): e1000147., PMID: 18773118  
 Region 1, Region 2Klein MM, Gittis AG, Su HP, Makobongo MO, Moore JM, Singh S, Miller LH, Garboczi DN. "The cysteine-rich interdomain region from the highly variable plasmodium falciparum erythrocyte membrane protein-1 exhibits a conserved structure." PLoS Pathog.. 2008; 4(9): e1000147., PMID: 18773118  
DP00747_C002Region 1Ralat LA, Funke T, Ren M, Guo Q, Dickey DM, Potter LR, Tang W-J. "Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human atrial natriuretic peptide (ANP)." PDB Primary Citation. 2010. 
 Region 1He XL, Dukkipati A, Garcia KC. "Structural determinants of natriuretic peptide receptor specificity and degeneracy." J. Mol. Biol.. 2006; 361(4): 698-714., PMID: 16870210  
 Region 1Fairbrother WJ, McDowell RS, Cunningham BC. "Solution conformation of an atrial natriuretic peptide variant selective for the type A receptor." Biochemistry. 1994; 33(30): 8897-904., PMID: 8043577  
 Region 1Feller SM, Lewitzky M. "What is in a loop?" Cell Commun. Signal. 2012; 10(1): 31., PMID: 23110718  
DP00748 Feller SM, Lewitzky M. "What is in a loop?" Cell Commun. Signal. 2012; 10(1): 31., PMID: 23110718  
 Region 9Donaldson LW, Gish G, Pawson T, Kay LE, Forman-Kay JD. "Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide." Proc. Natl. Acad. Sci. U.S.A.. 2002; 99(22): 14053-8., PMID: 12384576  
 Region 1, Region 2, Region 3, Region 4, Region 5, Region 6, Region 7, Region 8Kobashigawa Y, Sakai M, Naito M, Yokochi M, Kumeta H, Makino Y, Ogura K, Tanaka S, Inagaki F. "Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK." Nat. Struct. Mol. Biol.. 2007; 14(6): 503-10., PMID: 17515907  
DP00748_A002Region 1, Region 2, Region 3, Region 4, Region 5Kobashigawa Y, Sakai M, Naito M, Yokochi M, Kumeta H, Makino Y, Ogura K, Tanaka S, Inagaki F. "Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK." Nat. Struct. Mol. Biol.. 2007; 14(6): 503-10., PMID: 17515907  



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