DP00037: Probable peroxiredoxinFASTA viewXML view

General information
DisProt:DP00037
Name:Probable peroxiredoxin
Synonym(s):TDXH_AERPE
EC 1.11.1.15
First appeared in release:Release 3.0 (02/17/2006)
UniProt:Q9Y9L0
UniGene: 
SwissProt: TDXH_AERPE
TrEMBL:  
NCBI (GI): 14285795
Source organism:Aeropyrum pernix
Sequence length:250
Percent disordered:10%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MPGSIPLIGE RFPEMEVTTD HGVIKLPDHY VSQGKWFVLF SHPADFTPVC TTEFVSFARR - 60
YEDFQRLGVD LIGLSVDSVF SHIKWKEWIE RHIGVRIPFP IIADPQGTVA RRLGLLHAES - 120
ATHTVRGVFI VDARGVIRTM LYYPMELGRL VDEILRIVKA LKLGDSLKRA VPADWPNNEI - 180
IGEGLIVPPP TTEDQARARM ESGQYRCLDW WFCWDTPASR DDVEEARRYL RRAAEKPAKL - 240
LYEEARTHLH

Region 1: 2-8 Region 4: 197-206 Region 5: 235-243

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name:N-terminal
Location:2 - 8
Length:7
Region sequence:

PGSIPLI

Modification type: Monomeric
PDB: 2CV4:A
Structural/functional type:  
Functional classes:  
Functional subclasses: Substrate/ligand binding
Apoptosis Regulation
Detection methods:
  1. X-ray crystallography (291 K; DTT 1 mM; NaCl 150 mM; Tris-HCl (pH 8.0) 20 mM)

References:
  1. Mizohata E, Sakai H, Fusatomi E, Terada T, Murayama K, Shirouzu M, Yokoyama S. "Crystal Structure of an Archaeal Peroxiredoxin from the Aerobic Hyperthermophilic Crenarchaeon Aeropyrum pernix K1." J Mol Biol. 2005. PubMed: 16214169

Comments:
 



Region 4
Type:Disordered
Name: 
Location:197 - 206
Length:10
Region sequence:

RARMESGQYR

Modification type: Monomeric
PDB: 2CV4:A
Structural/functional type:  
Functional classes:  
Functional subclasses: Apoptosis Regulation
Substrate/ligand binding
Detection methods:
  1. X-ray crystallography (291 K; DTT 1 mM; NaCl 150 mM; Tris-HCl (pH 8.0) 20 mM)

References:
  1. Mizohata E, Sakai H, Fusatomi E, Terada T, Murayama K, Shirouzu M, Yokoyama S. "Crystal Structure of an Archaeal Peroxiredoxin from the Aerobic Hyperthermophilic Crenarchaeon Aeropyrum pernix K1." J Mol Biol. 2005. PubMed: 16214169

Comments:
 



Region 5
Type:Disordered
Name:C-terminal tail
Location:235 - 243
Length:9
Region sequence:

EKPAKLLYE

Modification type: Monomeric
PDB: 2CV4:A
Structural/functional type:  
Functional classes:  
Functional subclasses: Apoptosis Regulation
Substrate/ligand binding
Detection methods:
  1. X-ray crystallography (291 K; DTT 1 mM; NaCl 150 mM; Tris-HCl (pH 8.0) 20 mM)

References:
  1. Mizohata E, Sakai H, Fusatomi E, Terada T, Murayama K, Shirouzu M, Yokoyama S. "Crystal Structure of an Archaeal Peroxiredoxin from the Aerobic Hyperthermophilic Crenarchaeon Aeropyrum pernix K1." J Mol Biol. 2005. PubMed: 16214169

Comments:
 



References

  1. Mizohata E, Sakai H, Fusatomi E, Terada T, Murayama K, Shirouzu M, Yokoyama S. "Crystal Structure of an Archaeal Peroxiredoxin from the Aerobic Hyperthermophilic Crenarchaeon Aeropyrum pernix K1." J Mol Biol. 2005. PubMed: 16214169



Comments


AV 6-28-2010 PubMed: 16214169


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