General information | DisProt: | DP00042 | Name: | Non-histone chromosomal protein H6 | Synonym(s): | H6_ONCMY
Histone T
High mobility group H6
Oncorhyncin-3 [cleavage product 1]
Oncorhyncin III
| First appeared in release: | Release 2.0 (02/14/2005) | UniProt: | P02315 | UniGene: | | SwissProt: | H6_ONCMY | TrEMBL: | | NCBI (GI): | 462245 | Source organism: | Oncorhynchus mykiss (Rainbow trout)(Salmo gairdneri) | Sequence length: | 70 | Percent disordered: | 99% | Homologues: | |
Native sequence |
10 20 30 40 50 60 | | | | | | MPKRKSATKG DEPARRSARL SARPVPKPAA KPKKAAAPKK AVKGKKAAEN GDAKAEAKVQ - 60 AAGDGAGNAK
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Functional narrative |
Non-histone protein that probably binds to the inner side of nucleosomal DNA, altering the association between the DNA and the nucleosome octamer.
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Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
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Region 1 | Type: | Disordered - Extended | Name: | | Location: | 2 - 70 | Length: | 69 | Region sequence: |
PKRKSATKGDEPARRSARLSARPVPKPAAKPKKAAAPKKAVKGKKAAENGDAKAEAKVQA AGDGAGNAK | Modification type: | | PDB: | | Structural/functional type: | Function arises via a disorder to order transition | Functional classes: | Molecular assembly
| Functional subclasses: | Protein-DNA binding
| Detection methods:
- Circular dichroism (CD) spectroscopy, far-UV
- Nuclear magnetic resonance (NMR)
| References:
- Cary PD, Crane-Robinson C, Bradbury EM, Dixon GH. "Structural studies of the non-histone chromosomal proteins HMG-T and H6 from trout testis." Eur J Biochem. 1981; 119(3): 545-51. PubMed: 6273163
| Comments:
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Comments |
Disordered residues lie within the region corresponding to Oncorhyncin III, however, there are no references to confirm that the cleavage product is disordered.
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