DP00058: Prothymosin alphaFASTA viewXML view

General information
DisProt:DP00058
Name:Prothymosin alpha
Synonym(s):PTMA_RAT
Thymosin alpha [cleavage chain 1]
First appeared in release:Release 1.0 (08/01/2003)
UniProt:P06302
UniGene:Rn.817
SwissProt: PTMA_RAT
TrEMBL:  
NCBI (GI): 135836
Source organism:Rattus norvegicus (Rat)
Sequence length:112
Percent disordered:100%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MSDAAVDTSS EITTKDLKEK KEVVEEAENG RDAPANGNAQ NEENGEQEAD NEVDEEEEEG - 60
GEEEEEEEEG DGEEEDGDED EEAEAPTGKR VAEDDEDDDV ETKKQKKTDE DD

Region 1: 1-112

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:1 - 112
Length:112
Region sequence:

MSDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNAQNEENGEQEADNEVDEEEEEG
GEEEEEEEEGDGEEEDGDEDEEAEAPTGKRVAEDDEDDDVETKKQKKTDEDD

Modification type: Monomeric
Native
PDB:  
Structural/functional type:  
Functional classes: Unknown
Functional subclasses: Unknown
Detection methods:
  1. Dynamic light scattering (293 K; output power 1 W; scattering angle 90 ; wavelength 514.5 nm)

  2. Static light scattering (293 K; output power 1 W; scattering angle 90 ; wavelength 514.5 nm)

  3. Small-angle X-ray scattering (SAXS) (URD6 (X-ray diffractometer))

  4. Circular dichroism (CD) spectroscopy, far-UV (293 K; pH: 7.4; Jasco J-720 (spectrometer); PBS (buffer))

References:
  1. Gast K, Damaschun H, Eckert K, Schulze-Forster K, Maurer HR, Muller-Frohne M, Zirwer D, Czarnecki J, Damaschun G. "Prothymosin alpha: a biologically active protein with random coil conformation." Biochemistry. 1995; 34(40): 13211-8. PubMed: 7548085

Comments:
 



References

  1. Gast K, Damaschun H, Eckert K, Schulze-Forster K, Maurer HR, Muller-Frohne M, Zirwer D, Czarnecki J, Damaschun G. "Prothymosin alpha: a biologically active protein with random coil conformation." Biochemistry. 1995; 34(40): 13211-8. PubMed: 7548085



Comments


AV 6-28-2010 PubMed: 7548085


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