Annotation for this protein is in progress - please check future releases for more complete information


DP00098: Collagen adhesinFASTA viewXML view

General information
DisProt:DP00098
Name:Collagen adhesin
Synonym(s):CNA_STAAU
First appeared in release:Release 3.0 (02/17/2006)
UniProt:Q53654
UniGene: 
SwissProt: CNA_STAAU
TrEMBL:  
NCBI (GI): 3913259
Source organism:Staphylococcus aureus
Sequence length:1183
Percent disordered:2%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MNKNVLKFMV FIMLLNIITP LFNKNEAFAA RDISSTNVTD LTVSPSKIED GGKTTVKMTF - 60
DDKNGKIQNG DMIKVAWPTS GTVKIEGYSK TVPLTVKGEQ VGQAVITPDG ATITFNDKVE - 120
KLSDVSGFAE FEVQGRNLTQ TNTSDDKVAT ITSGNKSTNV TVHKSEAGTS SVFYYKTGDM - 180
LPEDTTHVRW FLNINNEKSY VSKDITIKDQ IQGGQQLDLS TLNINVTGTH SNYYSGQSAI - 240
TDFEKAFPGS KITVDNTKNT IDVTIPQGYG SYNSFSINYK TKITNEQQKE FVNNSQAWYQ - 300
EHGKEEVNGK SFNHTVHNIN ANAGIEGTVK GELKVLKQDK DTKAPIANVK FKLSKKDGSV - 360
VKDNQKEIEI ITDANGIANI KALPSGDYIL KEIEAPRPYT FDKDKEYPFT MKDTDNQGYF - 420
TTIENAKAIE KTKDVSAQKV WEGTQKVKPT IYFKLYKQDD NQNTTPVDKA EIKKLEDGTT - 480
KVTWSNLPEN DKNGKAIKYL VKEVNAQGED TTPEGYTKKE NGLVVTNTEK PIETTSISGE - 540
KVWDDKDNQD GKRPEKVSVN LLANGEKVKT LDVTSETNWK YEFKDLPKYD EGKKIEYTVT - 600
EDHVKDYTTD INGTTITNKY TPGETSATVT KNWDDNNNQD GKRPTEIKVE LYQDGKATGK - 660
TAILNESNNW THTWTGLDEK AKGQQVKYTV EELTKVKGYT THVDNNDMGN LIVTNKYTPE - 720
TTSISGEKVW DDKDNQDGKR PEKVSVNLLA DGEKVKTLDV TSETNWKYEF KDLPKYDEGK - 780
KIEYTVTEDH VKDYTTDING TTITNKYTPG ETSATVTKNW DDNNNQDGKR PTEIKVELYQ - 840
DGKATGKTAI LNESNNWTHT WTGLDEKAKG QQVKYTVEEL TKVKGYTTHV DNNDMGNLIV - 900
TNKYTPETTS ISGEKVWDDK DNQDGKRPEK VSVNLLANGE KVKTLDVTSE TNWKYEFKDL - 960
PKYDEGKKIE YTVTEDHVKD YTTDINGTTI TNKYTPGETS ATVTKNWDDN NNQDGKRPTE - 1020
IKVELYQDGK ATGKTAILNE SNNWTHTWTG LDEKAKGQQV KYTVDELTKV NGYTTHVDNN - 1080
DMGNLIVTNK YTPKKPNKPI YPEKPKDKTP PTKPDHSNKV KPTPPDKPSK VDKDDQPKDN - 1140
KTKPENPLKE LPKTGMKIIT SWITWVFIGI LGLYLILRKR FNS

Region 1: 151-168

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:151 - 168
Length:18
Region sequence:

ITSGNKSTNVTVHKSEAG

Modification type: Fragment
PDB: 1AMX:A
Structural/functional type: Relationship to function unknown
Functional classes: Unknown
Functional subclasses: Protein-protein binding
Detection methods:
  1. Circular dichroism (CD) spectroscopy, far-UV (298 K; )

  2. Circular dichroism (CD) spectroscopy, near-UV (298 K; )
References:
  1. Patti JM, Boles JO, Hook M. "Identification and biochemical characterization of the ligand binding domain of the collagen adhesin from Staphylococcus aureus." Biochemistry. 1993; 32(42): 11428-35. PubMed: 8218209

  2. Symersky J, Patti JM, Carson M, House-Pompeo K, Teale M, Moore D, Jin L, Schneider A, DeLucas LJ, Hook M, Narayana SV. "Structure of the collagen-binding domain from a Staphylococcus aureus adhesin." Nat Struct Biol. 1997; 4(10): 833-8. PubMed: 9334749
Comments:
 



Comments


As the Patti article does not contain evidence for disorder and the Symersky article is not publicly available, this record cannot be verified.


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