| Region 1 |
| Type: | Disordered |
| Name: | Flexible loop |
| Location: | 108 - 115 |
| Length: | 8 |
| Region sequence: |
VADKANPD |
| Modification type: | Mutant
|
| PDB: | 1DGK:A, 1DGK:B |
| Structural/functional type: | Function arises from the disordered state
|
| Functional classes: | Chaperones
|
| Functional subclasses: | Flexible linkers/spacers
Protein-DNA binding
Substrate/ligand binding
|
Detection methods:
- X-ray crystallography (100 K; pH: 4.6; resolution 2.8 A)
|
References:
- Harrison CJ, Hayer-Hartl M, Di Liberto M, Hartl F, Kuriyan J. "Crystal structure of the nucleotide exchange factor GrpE bound to the ATPase domain of the molecular chaperone DnaK." Science. 1997; 276(5311): 431-5. PubMed: 9103205
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Comments:Mutant G122D, in which Gly at position 122 is mutated to Asp was used.
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