Annotation for this protein is in progress - please check future releases for more complete information


DP00104: Transcription initiation factor IIA large subunitFASTA viewXML view

General information
DisProt:DP00104
Name:Transcription initiation factor IIA large subunit
Synonym(s):TOA1_YEAST
TFIIA large subunit
TFIIA 32 kDa subunit
First appeared in release:Release 3.0 (02/17/2006)
UniProt:P32773
UniGene: 
SwissProt: TOA1_YEAST
TrEMBL:  
NCBI (GI): 418108
Source organism:Saccharomyces cerevisiae (Baker's yeast)
Sequence length:286
Percent disordered:11%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MSNAEASRVY EIIVESVVNE VREDFENAGI DEQTLQDLKN IWQKKLTETK VTTFSWDNQF - 60
NEGNINGVQN DLNFNLATPG VNSSEFNIKE ENTGNEGLIL PNINSNNNIP HSGETNINTN - 120
TVEATNNSGA TLNTNTSGNT NADVTSQPKI EVKPEIELTI NNANITTVEN IDDESEKKDD - 180
EEKEEDVEKT RKEKEQIEQV KLQAKKEKRS ALLDTDEVGS ELDDSDDDYL ISEGEEDGPD - 240
ENLMLCLYDK VTRTKARWKC SLKDGVVTIN RNDYTFQKAQ VEAEWV

Region 1: 210-240

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:210 - 240
Length:31
Region sequence:

SALLDTDEVGSELDDSDDDYLISEGEEDGPD

Modification type: Complex
Fragment
PDB:  
Structural/functional type:  
Functional classes:  
Functional subclasses: Transactivation (transcriptional activation)
Protein-protein binding
Detection methods:
  1. X-ray crystallography (103 K; )
References:
  1. Tan S, Hunziker Y, Sargent DF, Richmond TJ. "Crystal structure of a yeast TFIIA/TBP/DNA complex." Nature. 1996; 381(6578): 127-51. PubMed: 8610010
Comments:
The fragment used for structure determination consisted of the C-terminal 76 residues.(aa210-aa286)


References

  1. Burley SK. "Picking up the TAB." Nature. 1996; 381(6578): 112-3. PubMed: 8610004


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