Annotation for this protein is in progress - please check future releases for more complete information


DP00105: Diol dehydrase beta subunitFASTA viewXML view

General information
DisProt:DP00105
Name:Diol dehydrase beta subunit
Synonym(s):Q59471_KLEOX
EC=4.2.1.28
First appeared in release:Release 1.0 (08/01/2003)
UniProt:Q59471
UniGene: 
SwissProt: Q59471_KLEOX
TrEMBL:  
NCBI (GI): 75350363
Source organism:Klebsiella oxytoca
Sequence length:224
Percent disordered:20%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MEINEKLLRQ IIEDVLSEMK GSDKPVSFNA PAASAAPQAT PPAGDGFLTE VGEARQGTQQ - 60
DEVIIAVGPA FGLAQTVNIV GIPHKSILRE VIAGIEEEGI KARVIRCFKS SDVAFVAVEG - 120
NRLSGSGISI GIQSKGTTVI HQQGLPPLSN LELFPQAPLL TLETYRQIGK NAARYAKRES - 180
PQPVPTLNDQ MARPKYQAKS AILHIKETKY VVTGKNPQEL RVAL

Region 1: 1-45

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:1 - 45
Length:45
Region sequence:

MEINEKLLRQIIEDVLSEMKGSDKPVSFNAPAASAAPQATPPAGD

Modification type: Complex
PDB: 1EGM:B
Structural/functional type:  
Functional classes:  
Functional subclasses:  
Detection methods:
  1. X-ray crystallography (1,2-propanediol (2.0%); Cyanocobalamin 2.5 mM; lauryldimethylamine oxide (LDAO) (0.10%); Potassium phosphate buffer (pH 8.0) 10 mM)
References:
  1. Shibata N, Masuda J, Tobimatsu T, Toraya T, Suto K, Morimoto Y, Yasuoka N. "A new mode of B12 binding and the direct participation of a potassium ion in enzyme catalysis: X-ray structure of diol dehydratase." Structure Fold Des. 1999; 7(8): 997-1008. PubMed: 10467140
Comments:
 


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