Annotation for this protein is in progress - please check future releases for more complete information



DP00176: Fe(3+)-pyochelin receptorFASTA viewXML view

General information
DisProt:DP00176
Name:Fe(3+)-pyochelin receptor
Synonym(s):FPTA_PSEAE
Fe(III)-pyochelin receptor
First appeared in release:Release 3.0 (02/17/2006)
UniProt:P42512
UniGene: 
SwissProt: FPTA_PSEAE
TrEMBL:  
NCBI (GI): 1169730
Source organism:Pseudomonas aeruginosa
Sequence length:720
Percent disordered:6%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MKTETKVIKG RQGIARNRHT PLCLGLLLAL SPLAAAVADA RKDGETELPD MVISGESTSA - 60
TQPPGVTTLG KVPLKPRELP QSASVIDHER LEQQNLFSLD EAMQQATGVT VQPFQLLTTA - 120
YYVRGFKVDS FELDGVPALL GNTASSPQDM AIYERVEILR GSNGLLHGTG NPAATVNLVR - 180
KRPQREFAAS TTLSAGRWDR YRAEVDVGGP LSASGNVRGR AVAAYEDRDY FYDVADQGTR - 240
LLYGVTEFDL SPDTLLTVGA QYQHIDSITN MAGVPMAKDG SNLGLSRDTY LDVDWDRFKW - 300
DTYRAFGSLE QQLGGGWKGK VSAEYQEADS RLRYAGSFGA IDPQTGDGGQ LMGAAYKFKS - 360
IQRSLDANLN GPVRLFGLTH ELLGGVTYAQ GETRQDTARF LNLPNTPVNV YRWDPHGVPR - 420
PQIGQYTSPG TTTTTQKGLY ALGRIKLAEP LTLVVGGRES WWDQDTPATR FKPGRQFTPY - 480
GGLIWDFARD WSWYVSYAEV YQPQADRQTW NSEPLSPVEG KTYETGIKGE LADGRLNLSL - 540
AAFRIDLENN PQEDPDHPGP PNNPFYISGG KVRSQGFELE GTGYLTPYWS LSAGYTYTST - 600
EYLKDSQNDS GTRYSTFTPR HLLRLWSNYD LPWQDRRWSV GGGLQAQSDY SVDYRGVSMR - 660
QGGYALVNMR LGYKIDEHWT AAVNVNNLFD RTYYQSLSNP NWNNRYGEPR SFNVSLRGAF - 720

Region 1: 38-55 Region 3: 504-513 Region 2: 551-568

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:38 - 55
Length:18
Region sequence:

ADARKDGETELPDMVISG

Modification type: Complex
PDB:  
Structural/functional type: Function arises from the disordered state
Functional classes: Molecular assembly
Functional subclasses: Substrate/ligand binding
Detection methods:
  1. X-ray crystallography (ethylene glycol (25% (v/v)); (NH4)2SO4 0.15 M; PEG 10,000 (6% (w/v)); Sodium acetate buffer (pH 4.6) 0.1 M)

References:
  1. Cobessi D, Celia H, Pattus F. "Crystal structure at high resolution of ferric-pyochelin and its membrane receptor FptA from Pseudomonas aeruginosa." J Mol Biol. 2005; 352(4): 893-904. PubMed: 16139844

Comments:
 



Region 2
Type:Disordered
Name:Loop L8
Location:551 - 568
Length:18
Region sequence:

PQEDPDHPGPPNNPFYIS

Modification type: Complex
PDB:  
Structural/functional type:  
Functional classes:  
Functional subclasses: Substrate/ligand binding
Detection methods:
  1. X-ray crystallography (ethylene glycol (25% (v/v)); (NH4)2SO4 0.15 M; PEG 10,000 (6% (w/v)); Sodium acetate buffer (pH 4.6) 0.1 M)

References:
  1. Cobessi D, Celia H, Pattus F. "Crystal structure at high resolution of ferric-pyochelin and its membrane receptor FptA from Pseudomonas aeruginosa." J Mol Biol. 2005; 352(4): 893-904. PubMed: 16139844

Comments:
 



Region 3
Type:Disordered
Name:Loop L7
Location:504 - 513
Length:10
Region sequence:

QADRQTWNSE

Modification type: Complex
PDB:  
Structural/functional type:  
Functional classes:  
Functional subclasses: Substrate/ligand binding
Detection methods:
  1. X-ray crystallography (ethylene glycol (25% (v/v)); (NH4)2SO4 0.15 M; PEG 10,000 (6% (w/v)); Sodium acetate buffer (pH 4.6) 0.1 M)

References:
  1. Cobessi D, Celia H, Pattus F. "Crystal structure at high resolution of ferric-pyochelin and its membrane receptor FptA from Pseudomonas aeruginosa." J Mol Biol. 2005; 352(4): 893-904. PubMed: 16139844

Comments:
 


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