DP00180_C003: Salt-mediated killer toxin 1 beta chainFASTA viewXML view

General information
DisProt:DP00180_C003
Name:Salt-mediated killer toxin 1 beta chain
Synonym(s):TOXK_PICFA
SMK toxin beta chain
cleavage product 3 of Salt-mediated killer protoxin 1
First appeared in release:Release 2.0 (02/14/2005)
UniProt:P19972
UniGene: 
SwissProt: TOXK_PICFA
TrEMBL:  
NCBI (GI): 18266832
Source organism:Pichia farinosa (Yeast)
Sequence length:77
Percent disordered:100%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
GEATTIWGVG ADEAIDKGTP SKNDLQNMSA DLAKNGFKGH QGVACSTVKD GNKDVYMIKF - 60
SLAGGSNDPG GSPCSDD



Functional narrative    

Beta subunit of a toxin that kills sensitive strains of yeast. Salt-mediated killer toxin 1 beta chain is cleavage product 3 of Salt-mediated killer protoxin 1, comprised of aa 146-222 of the polyprotein.

Region 1: 1-77

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name:SMK toxin beta chain
Location:1 - 77
Length:77
Region sequence:

GEATTIWGVGADEAIDKGTPSKNDLQNMSADLAKNGFKGHQGVACSTVKDGNKDVYMIKF
SLAGGSNDPGGSPCSDD

Modification type: Native
PDB:  
Structural/functional type: Function arises via a disorder to order transition
Functional classes: Molecular assembly
Functional subclasses: Protein-protein binding
Detection methods:
  1. Circular dichroism (CD) spectroscopy, far-UV (298 K; pH: 7; )

References:
  1. Suzuki C, Kashiwagi T, Tsuchiya F, Kunishima N, Morikawa K, Nikkuni S, Arata Y. "Circular dichroism analysis of the interaction between the alpha and beta subunits in a killer toxin produced by a halotolerant yeast, Pichia farinosa." Protein Eng. 1997; 10(2): 99-101. PubMed: 9089808

Comments:
 



Comments


Previous entry DP00180 has been split into polyprotein entry DP00180 and cleavage product 3 entry DP00180_C003. Disorder is characterized on the cleavage product.


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