General information | DisProt: | DP00180_C003 | Name: | Salt-mediated killer toxin 1 beta chain | Synonym(s): | TOXK_PICFA
SMK toxin beta chain
cleavage product 3 of Salt-mediated killer protoxin 1
| First appeared in release: | Release 2.0 (02/14/2005) | UniProt: | P19972 | UniGene: | | SwissProt: | TOXK_PICFA | TrEMBL: | | NCBI (GI): | 18266832 | Source organism: | Pichia farinosa (Yeast) | Sequence length: | 77 | Percent disordered: | 100% | Homologues: | |
Native sequence |
10 20 30 40 50 60 | | | | | | GEATTIWGVG ADEAIDKGTP SKNDLQNMSA DLAKNGFKGH QGVACSTVKD GNKDVYMIKF - 60 SLAGGSNDPG GSPCSDD
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Functional narrative |
Beta subunit of a toxin that kills sensitive strains of yeast. Salt-mediated killer toxin 1 beta chain is cleavage product 3 of Salt-mediated killer protoxin 1, comprised of aa 146-222 of the polyprotein.
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Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
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Region 1 | Type: | Disordered | Name: | SMK toxin beta chain | Location: | 1 - 77 | Length: | 77 | Region sequence: |
GEATTIWGVGADEAIDKGTPSKNDLQNMSADLAKNGFKGHQGVACSTVKDGNKDVYMIKF SLAGGSNDPGGSPCSDD | Modification type: | Native
| PDB: | | Structural/functional type: | Function arises via a disorder to order transition | Functional classes: | Molecular assembly
| Functional subclasses: | Protein-protein binding
| Detection methods:
- Circular dichroism (CD) spectroscopy, far-UV (298 K; pH: 7; )
| References:
- Suzuki C, Kashiwagi T, Tsuchiya F, Kunishima N, Morikawa K, Nikkuni S, Arata Y. "Circular dichroism analysis of the interaction between the alpha and beta subunits in a killer toxin produced by a halotolerant yeast, Pichia farinosa." Protein Eng. 1997; 10(2): 99-101. PubMed: 9089808
| Comments:
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Comments |
Previous entry DP00180 has been split into polyprotein entry DP00180 and cleavage product 3 entry DP00180_C003. Disorder is characterized on the cleavage product.
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