Annotation for this protein is in progress - please check future releases for more complete information


DP00267: Potassium voltage-gated channel protein Shaker [Isoform E]FASTA viewXML view

General information
DisProt:DP00267
Name:Potassium voltage-gated channel protein Shaker [Isoform E]
Synonym(s):KCNAS_DROME
Protein minisleep
First appeared in release:Release 3.0 (02/17/2006)
UniProt:P08510-1
UniGene:Dm.7088
SwissProt: KCNAS_DROME
TrEMBL:  
NCBI (GI): 92090610
Source organism:Drosophila melanogaster (Fruit fly)
Sequence length:655
Percent disordered:10%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MAAVAGLYGL GEDRQHRKKQ QQQQQHQKEQ LEQKEEQKKI AERKLQLREQ QLQRNSLDGY - 60
GSLPKLSSQD EEGGAGHGFG GGPQHFEPIP HDHDFCERVV INVSGLRFET QLRTLNQFPD - 120
TLLGDPARRL RYFDPLRNEY FFDRSRPSFD AILYYYQSGG RLRRPVNVPL DVFSEEIKFY - 180
ELGDQAINKF REDEGFIKEE ERPLPDNEKQ RKVWLLFEYP ESSQAARVVA IISVFVILLS - 240
IVIFCLETLP EFKHYKVFNT TTNGTKIEED EVPDITDPFF LIETLCIIWF TFELTVRFLA - 300
CPNKLNFCRD VMNVIDIIAI IPYFITLATV VAEEEDTLNL PKAPVSPQDK SSNQAMSLAI - 360
LRVIRLVRVF RIFKLSRHSK GLQILGRTLK ASMRELGLLI FFLFIGVVLF SSAVYFAEAG - 420
SENSFFKSIP DAFWWAVVTM TTVGYGDMTP VGVWGKIVGS LCAIAGVLTI ALPVPVIVSN - 480
FNYFYHRETD QEEMQSQNFN HVTSCPYLPG TLGQHMKKSS LSESSSDMMD LDDGVESTPG - 540
LTETHPGRSA VAPFLGAQQQ QQQPVASSLS MSIDKQLQHP LQQLTQTQLY QQQQQQQQQQ - 600
QNGFKQQQQQ TQQQLQQQQS HTINASAAAA TSGSGSSGLT MRHNNALAVS IETDV

Region 1: 20-83

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:20 - 83
Length:64
Region sequence:

QQQQQQHQKEQLEQKEEQKKIAERKLQLREQQLQRNSLDGYGSLPKLSSQDEEGGAGHGF
GGGP

Modification type: Mutant
Native
PDB:  
Structural/functional type: Function arises from the disordered state
Functional classes: Entropic chain
Functional subclasses: Entropic clock
Flexible linkers/spacers
Detection methods:
 
References:
  1. Hoshi T, Zagotta WN, Aldrich RW. "Biophysical and molecular mechanisms of Shaker potassium channel inactivation." Science. 1990; 250(4980): 533-8. PubMed: 2122519
Comments:
 


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