Annotation for this protein is in progress - please check future releases for more complete information


DP00302: Putative stringent starvation protein AFASTA viewXML view

General information
DisProt:DP00302
Name:Putative stringent starvation protein A
Synonym(s):Q7CL96_YERPE
Regulator of transcription; stringent starvation protein A
SspA
First appeared in release:Release 3.0 (02/17/2006)
UniProt:Q7CL96
UniGene: 
SwissProt: Q7CL96_YERPE
TrEMBL:  
NCBI (GI): 123776518
Source organism:Yersinia pestis
Sequence length:213
Percent disordered:11%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MAVAANKRSV MTLFSGPTDI FSHQVRIVLA EKGVSVEIEQ VEADNLPQDL IDLNPYRTVP - 60
TLVDRELTLY ESRIIMEYLD ERFPHPPLMP VYPVARGSSR LMMHRIEHDW YSLLYKIEQG - 120
NAQEAEAARK QLREELLSIA PVFNETPFFM SEEFSLVDCY LAPLLWRLPV LGIEFTGAGS - 180
KELKGYMTRV FERDAFLASL TEAEREMHLK TRS

Region 1: 1-9 Region 2: 48-53 Region 3: 204-212

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:1 - 9
Length:9
Region sequence:

MAVAANKRS

Modification type:  
PDB: 1YY7:B
Structural/functional type: Relationship to function unknown
Functional classes: Unknown
Functional subclasses: Transactivation (transcriptional activation)
Detection methods:
  1. X-ray crystallography
References:
  1. Hansen AM, Gu Y, Li M, Andrykovitch M, Waugh DS, Jin DJ, Ji X. "Structural basis for the function of stringent starvation protein a as a transcription factor." J Biol Chem. 2005; 280(17): 17380-91. PubMed: 15735307
Comments:
 



Region 2
Type:Disordered
Name:alpha-2 helix
Location:48 - 53
Length:6
Region sequence:

QDLIDL

Modification type:  
PDB:  
Structural/functional type: Function arises from the disordered state
Functional classes: Molecular recognition effectors
Functional subclasses: Transactivation (transcriptional activation)
Detection methods:
  1. X-ray crystallography
References:
  1. Hansen AM, Gu Y, Li M, Andrykovitch M, Waugh DS, Jin DJ, Ji X. "Structural basis for the function of stringent starvation protein a as a transcription factor." J Biol Chem. 2005; 280(17): 17380-91. PubMed: 15735307
Comments:
 



Region 3
Type:Disordered
Name: 
Location:204 - 212
Length:9
Region sequence:

EREMHLKTR

Modification type:  
PDB: 1YY7:A
Structural/functional type: Relationship to function unknown
Functional classes: Unknown
Functional subclasses: Transactivation (transcriptional activation)
Detection methods:
  1. X-ray crystallography
References:
  1. Hansen AM, Gu Y, Li M, Andrykovitch M, Waugh DS, Jin DJ, Ji X. "Structural basis for the function of stringent starvation protein a as a transcription factor." J Biol Chem. 2005; 280(17): 17380-91. PubMed: 15735307
Comments:
 



References

  1. Andrykovitch M, Routzahn KM, Li M, Gu Y, Waugh DS, Ji X. "Characterization of four orthologs of stringent starvation protein A." Acta Crystallogr D Biol Crystallogr. 2003; 59(Pt 5): 881-6. PubMed: 12777805


If you have any comments or wish to provide additional references to this protein or its disordered region(s), please click here to e-mail us.


Disprot-footer
Contact us