Annotation for this protein is in progress - please check future releases for more complete information


DP00306: Early activation antigen CD69FASTA viewXML view

General information
DisProt:DP00306
Name:Early activation antigen CD69
Synonym(s):CD69_HUMAN
Early T-cell activation antigen p60
GP32/28
Leu-23
MLR-3
EA1
BL-AC/P26
Activation inducer molecule
AIM
First appeared in release:Release 3.0 (02/17/2006)
UniProt:Q07108
UniGene:Hs.208854
SwissProt: CD69_HUMAN
TrEMBL:  
NCBI (GI): 584906
Source organism:Homo sapiens (Human)
Sequence length:199
Percent disordered:42%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MSSENCFVAE NSSLHPESGQ ENDATSPHFS TRHEGSFQVP VLCAVMNVVF ITILIIALIA - 60
LSVGQYNCPG QYTFSMPSDS HVSSCSEDWV GYQRKCYFIS TVKRSWTSAQ NACSEHGATL - 120
AVIDSEKDMN FLKRYAGREE HWVGLKKEPG HPWKWSNGKE FNNWFNVTGS DKCVFLKNTE - 180
VSSMECEKNL YWICNKPYK



Functional narrative    

Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.

Region 1: 1-84

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:1 - 84
Length:84
Region sequence:

MSSENCFVAENSSLHPESGQENDATSPHFSTRHEGSFQVPVLCAVMNVVFITILIIALIA
LSVGQYNCPGQYTFSMPSDSHVSS

Modification type:  
PDB: 1FM5:A
Structural/functional type:  
Functional classes:  
Functional subclasses:  
Detection methods:
 
References:
  1. Natarajan K, Sawicki MW, Margulies DH, Mariuzza RA. "Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells." Biochemistry. 2000; 39(48): 14779-86. PubMed: 11101293
Comments:
 



Comments


This disordered protein entry is based solely on missing electron density in the Protein Data Bank.


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