| General information | | DisProt: | DP00382 | | Name: | Ribonuclease P protein component 1 | | Synonym(s): | RNP1_ARCFU
RNase P component 1
EC=3.1.26.5
aRpp29
| | First appeared in release: | Release 3.0 (02/17/2006) | | UniProt: | O28362 | | UniGene: | | | SwissProt: | RNP1_ARCFU | | TrEMBL: | | | NCBI (GI): | 6226474 | | Source organism: | Archaeoglobus fulgidus | | Sequence length: | 102 | | Percent disordered: | 39% | | Homologues: | |
| Native sequence |
10 20 30 40 50 60
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MRGRLQGVEL IARDWIGLMV EVVESPNHSE VGIKGEVVDE TQNTLKIMTE KGLKVVAKRG - 60
RTFRVWYKGK IMRIKGDLIN FRPEDRIKRG LMMLKRAKGV WI
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| Functional narrative |
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
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| Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
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| Region 1 | | Type: | Disordered | | Name: | | | Location: | 1 - 16 | | Length: | 16 | | Region sequence: |
MRGRLQGVALIARDWI | | Modification type: | Native
| | PDB: | | | Structural/functional type: | | | Functional classes: | | | Functional subclasses: | | Detection methods:
- Nuclear magnetic resonance (NMR) (303 K; K2HPO4/KH2PO4 (pH 5.8) 10 mM; NaCl 100 mM)
- Circular dichroism (CD) spectroscopy, far-UV (298 K; NaF 100 mM; Potassium phosphate (pH 7.0) 10 mM)
- Analytical ultracentrifugation (293 K; K2HPO4/KH2PO4 (pH 5.8) 10 mM; NaCl 100 mM)
| References:
- Sidote DJ, Heideker J, Hoffman DW. "Crystal structure of archaeal ribonuclease P protein aRpp29 from Archaeoglobus fulgidus." Biochemistry. 2004; 43(44): 14128-38. PubMed: 15518563
| Comments:
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| Region 2 | | Type: | Disordered | | Name: | | | Location: | 79 - 102 | | Length: | 24 | | Region sequence: |
INFRPEDRIKRGLMMLKRAKGVWI | | Modification type: | Native
| | PDB: | | | Structural/functional type: | | | Functional classes: | | | Functional subclasses: | | Detection methods:
- Nuclear magnetic resonance (NMR) (303 K; K2HPO4/KH2PO4 (ph 5.8) 10 mM; NaCl 100 mM)
- Circular dichroism (CD) spectroscopy, far-UV (298 K; NaF 100 mM; Potassium phosphate (pH 7.0) 10 mM)
- Analytical ultracentrifugation (293 K; K2HPO4/KH2PO4 (pH 5.8) 10 mM; NaCl 100 mM)
| References:
- Sidote DJ, Heideker J, Hoffman DW. "Crystal structure of archaeal ribonuclease P protein aRpp29 from Archaeoglobus fulgidus." Biochemistry. 2004; 43(44): 14128-38. PubMed: 15518563
| Comments:
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