| General information | | DisProt: | DP00538 | | Name: | Latent membrane protein 2A | | Synonym(s): | A8CDV5_EBVG
| | First appeared in release: | Release 3.7 (01/28/2008) | | UniProt: | A8CDV5 | | UniGene: | | | SwissProt: | A8CDV5_EBVG | | TrEMBL: | | | NCBI (GI): | 1079590 | | Source organism: | Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4) | | Sequence length: | 118 | | Percent disordered: | 100% | | Homologues: | |
| Native sequence |
10 20 30 40 50 60
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MGSLEMVPMG AGPPSPGGDP DGDDGGNNSQ YPSASGSSGN TPTPPNDEER ESNEEPPPPY - 60
EDLDWGNGDR HSDYQPLGNQ DPSLYLGLQH DGNDGLPPPP YSPRDDSSQH IYEEAGRG
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| Functional narrative |
Epstein-Barr virus latency is maintained by the latent
membrane protein (LMP) 2A, which mimics the B-cell receptor
(BCR) and perturbs BCR signaling.
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| Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
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| Region 1 | | Type: | Disordered | | Name: | | | Location: | 1 - 118 | | Length: | 118 | | Region sequence: |
MGSLEMVPMGAGPPSPGGDPDGDDGGNNSQYPSASGSSGNTPTPPNDEERESNEEPPPPY
EDLDWGNGDRHSDYQPLGNQDPSLYLGLQHDGNDGLPPPPYSPRDDSSQHIYEEAGRG | | Modification type: | Native
| | PDB: | | | Structural/functional type: | | | Functional classes: | | | Functional subclasses: | | Detection methods:
- Nuclear magnetic resonance (NMR) (288 K; )
| References:
- Seo MD, Park SJ, Kim HJ, Lee BJ. "Identification of the WW domain-interaction sites in the unstructured N-terminal domain of EBV LMP 2A." FEBS Lett. 2007; 581(1): 65-70. PubMed: 17174309
| Comments:
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| References |
- Seo MD, Park SJ, Kim HJ, Lee BJ. "Identification of the WW domain-interaction sites in the unstructured N-terminal domain of EBV LMP 2A." FEBS Lett. 2007; 581(1): 65-70. PubMed: 17174309
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