Annotation for this protein is in progress - please check future releases for more complete information


DP00569: EMILIN1 proteinFASTA viewXML view

General information
DisProt:DP00569
Name:EMILIN1 protein
Synonym(s):Q96IH6_HUMAN
First appeared in release:Release 4.1 (07/10/2008)
UniProt:Q96IH6
UniGene:Hs.63348
SwissProt: Q96IH6_HUMAN
TrEMBL:  
NCBI (GI): 74751938
Source organism:Homo sapiens (Human)
Sequence length:347
Percent disordered:5%
Homologues: 


Native sequence

        10         20         30         40         50         60
         |          |          |          |          |          |
MADLGATKDR IISEINRLQQ EATEHATESE ERFRGLEEGQ AQAGQCPSLE GRLGRLEGVC - 60
ERLDTVAGGL QGLREGLSRH VAGLWAGLRE TNTTSQMQAA LLEKLVGGQA GLGRRLGALN - 120
SSLQLLEDRL HQLSLKDLTG EGTKGPAGEA GPPGPPGLQG PPGPAGPPGS PGKDGQEGPI - 180
GPPGPQGEQG VEGAPAAPVP QVAFSAALSL PRSEPGTVPF DRVLLNDGGY YDPETGVFTA - 240
PLAGRYLLSA VLTGHRHEKV EAVLSRSNQG VARVDSGGYE PEGLENKPVA ESQPSPGTLG - 300
VFSLILPLQA GDTVCVDLVM GQLAHSEEPL TIFSGALLYG DPELEHA

Region 1: 280-297

Map of ordered and disordered regions







Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.


Region 1
Type:Disordered
Name: 
Location:280 - 297
Length:18
Region sequence:

EPEGLENKPVAESQPSPG

Modification type: Native
PDB: 2OII:A
Structural/functional type: Function arises via a disorder to order transition
Functional classes: Modification site
Functional subclasses: Substrate/ligand binding
Protein-protein binding
Detection methods:
 
References:
  1. Verdone G, Doliana R, Corazza A, Colebrooke SA, Spessotto P, Bot S, Bucciotti F, Capuano A, Silvestri A, Viglino P, Campbell ID, Colombatti A, Esposito G. "The Solution Structure of EMILIN1 Globular C1q Domain Reveals a Disordered Insertion Necessary for Interaction with the {alpha}4{beta}1 Integrin." J Biol Chem. 2008; 283(27): 18947-56. PubMed: 18463100
Comments:
 



Comments


Protein involved in maintaining homeostatic bloodpressure.


If you have any comments or wish to provide additional references to this protein or its disordered region(s), please click here to e-mail us.


Disprot-footer
Contact us