General information | DisProt: | DP00667 | Name: | Dehydrin ERD14 | Synonym(s): | ERD14_ARATH
| First appeared in release: | Release 5.1 (05/28/2010) | UniProt: | P42763 | UniGene: | At.47606 | SwissProt: | ERD14_ARATH | TrEMBL: | | NCBI (GI): | 1169278 | Source organism: | Arabidopsis thaliana (Mouse-ear cress) | Sequence length: | 185 | Percent disordered: | 100% | Homologues: | |
Native sequence |
10 20 30 40 50 60 | | | | | | MAEEIKNVPE QEVPKVATEE SSAEVTDRGL FDFLGKKKDE TKPEETPIAS EFEQKVHISE - 60 PEPEVKHESL LEKLHRSDSS SSSSSEEEGS DGEKRKKKKE KKKPTTEVEV KEEEKKGFME - 120 KLKEKLPGHK KPEDGSAVAA APVVVPPPVE EAHPVEKKGI LEKIKEKLPG YHPKTTVEEE - 180 KKDKE
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Functional narrative |
Intrinsically disordered protein acting as a chaperone. Prevents heat-induced aggregation and/or inactivation of various substrates. Binds to acidic phospholipid vesicles without affecting membrane fluidity.
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Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
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Region 1 | Type: | Disordered | Name: | | Location: | 1 - 185 | Length: | 185 | Region sequence: |
MAEEIKNVPEQEVPKVATEESSAEVTDRGLFDFLGKKKDETKPEETPIASEFEQKVHISE PEPEVKHESLLEKLHRSDSSSSSSSEEEGSDGEKRKKKKEKKKPTTEVEVKEEEKKGFME KLKEKLPGHKKPEDGSAVAAAPVVVPPPVEEAHPVEKKGILEKIKEKLPGYHPKTTVEEE KKDKE | Modification type: | Native
| PDB: | | Structural/functional type: | | Functional classes: | Chaperones
| Functional subclasses: | | Detection methods:
- SDS-PAGE gel, Aberrant mobility on (373 K; BSA (control) 0.2 mg/mL; ERD14 (sample) 0.3 mg/mL; SDS-PAGE Gel (12.5%))
- Circular dichroism (CD) spectroscopy, far-UV (298 K; pH: 7.5; ERD14 (sample) 0.5 mg/mL; NaCl 100 mM; phosphate buffer (NaH2PO4) 10 mM)
- Nuclear magnetic resonance (NMR) (298 K; ERD14 (sample) 1 mM; H2O:D2O (9:1, v/v))
| References:
- Kovacs D, Kalmar E, Torok Z, Tompa P. "Chaperone Activity of ERD10 and ERD14, Two Disordered Stress-Related Plant Proteins." Plant Physiol. : 381-390. PubMed: 18359842
| Comments:
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Comments |
Additional UniGene ID: At.73066, At.73994
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