| General information | | DisProt: | DP00677 | | Name: | 16.9 kDa class I heat shock protein 1 | | Synonym(s): | HS16A_WHEAT
Heat shock protein 16.9A
HSP 16.9
Heat shock protein 17
Low molecular weight heat shock protein
| | First appeared in release: | Release 5.1 (05/28/2010) | | UniProt: | P12810 | | UniGene: | Ta.24332 | | SwissProt: | HS16A_WHEAT | | TrEMBL: | | | NCBI (GI): | 123545 | | Source organism: | Triticum aestivum (Wheat) | | Sequence length: | 151 | | Percent disordered: | 28% | | Homologues: | |
| Native sequence |
10 20 30 40 50 60
| | | | | |
MSIVRRSNVF DPFADLWADP FDTFRSIVPA ISGGSSETAA FANARVDWKE TPEAHVFKVD - 60
LPGVKKEEVK VEVEDGNVLV VSGERSREKE DKNDKWHRVE RSSGKFVRRF RLPEDAKVEE - 120
VKAGLENGVL TVTVPKAEVK KPEVKAIEIS G
|
| Functional narrative |
May form oligomeric structures.
Belongs to the small heat shock protein (HSP20) family.
|
| Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
|
| Region 1 | | Type: | Disordered | | Name: | N-terminal | | Location: | 1 - 42 | | Length: | 42 | | Region sequence: |
MSIVRRSNVFDPFADLWADPFDTFRSIVPAISGGSSETAAFA | | Modification type: | Native
| | PDB: | 1GME:A, 1GME:B, 1GME:C, 1GME:D | | Structural/functional type: | | | Functional classes: | Chaperones
| | Functional subclasses: | Substrate/ligand binding
| Detection methods:
- Analytical ultracentrifugation (298 K; pH: 7.5; dithiothreitol (DTT) 2 mM; HEPES 25 mM; KCl 150 mM; MgCl2 5 mM; rpm (8,000 and 10,000); varying protein sample sizes)
- Size exclusion/gel filtration chromatography (298 K; pH: 7.3; NaCl 200 mM; sodium phosphate 250 mM)
| References:
- vanMontfort, Rob L. M., Eman Basha, Kenneth L. Friedrich, Christine Slingsby, Elizabeth Vierling. "Crystal structure and assembly of a eukaryotic small heat shock protein." 2001; 8: 1025-1030. PubMed: 11702068
| Comments:HSP16.9 dodecamer is arranged as two disks. The assembly comprises 12 α-crystallin domains with 12 C-terminal extensions, and six ordered and six dis-
ordered N-terminal arms.
|
| References |
- vanMontfort, Rob L. M., Eman Basha, Kenneth L. Friedrich, Christine Slingsby, Elizabeth Vierling. "Crystal structure and assembly of a eukaryotic small heat shock protein." 2001; 8: 1025-1030. PubMed: 11702068
|
| If you have any comments or wish to provide additional references to this protein or its disordered region(s), please click here to e-mail us. |
Disprot-footer
|
