| General information | | DisProt: | DP00687 | | Name: | Cytochrome b-c1 complex subunit Rieske, mitochondrial | | Synonym(s): | UCRI_YEAST
EC=1.10.2.2
Ubiquinol-cytochrome c reductase iron-sulfur subunit
Rieske iron-sulfur protein
RISP
Complex III subunit 5
| | First appeared in release: | Release 5.1 (05/28/2010) | | UniProt: | P08067 | | UniGene: | | | SwissProt: | UCRI_YEAST | | TrEMBL: | | | NCBI (GI): | 136715 | | Source organism: | Saccharomyces cerevisiae (Baker's yeast) | | Sequence length: | 215 | | Percent disordered: | 6% | | Homologues: | |
| Native sequence |
10 20 30 40 50 60
| | | | | |
MLGIRSSVKT CFKPMSLTSK RLISQSLLAS KSTYRTPNFD DVLKENNDAD KGRSYAYFMV - 60
GAMGLLSSAG AKSTVETFIS SMTATADVLA MAKVEVNLAA IPLGKNVVVK WQGKPVFIRH - 120
RTPHEIQEAN SVDMSALKDP QTDADRVKDP QWLIMLGICT HLGCVPIGEA GDFGGWFCPC - 180
HGSHYDISGR IRKGPAPLNL EIPAYEFDGD KVIVG
|
| Functional narrative |
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The complex couples electron transfer from ubiquinol to cytochrome c.
|
| Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
|
| Region 1 | | Type: | Disordered | | Name: | | | Location: | 81 - 92 | | Length: | 12 | | Region sequence: |
SMTATADVLAMA | | Modification type: | Fragment
Monomeric
Native
| | PDB: | 1EZV:E | | Structural/functional type: | Function arises from the disordered state
| | Functional classes: | Unknown
| | Functional subclasses: | Flexible linkers/spacers
| Detection methods:
- X-ray crystallography (277 K; pH: 8; PEG 4000 5 %; Stigmatellin (Inhibitor) 1 uM; Tris 100 mM; Undecyl-maltoside)
| References:
- Nett JH, Hunte C, Trumpower BL. "Changes to the length of the flexible linker region of the Rieske protein impair the interaction of ubiquinol with the cytochrome bc1 complex." Eur J Biochem. 2000; 267(18): 5777-82. PubMed: 10971589
| Comments:
|
| References |
- Uversky VN, Oldfield CJ, Dunker AK. "Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling." J Mol Recognit. 2005; 18(5): 343-84. PubMed: 16094605
|
| Comments |
Sent for AV - PubMed: 10971589 (8-26-2010)
|
| If you have any comments or wish to provide additional references to this protein or its disordered region(s), please click here to e-mail us. |
Disprot-footer
|
