| General information | | DisProt: | DP00744 | | Name: | Ribonucleotide reductase, small chain | | Synonym(s): | Q7RIF3_PLAYO
| | First appeared in release: | Release 6.02 (05/24/2013) | | UniProt: | Q7RIF3 | | UniGene: | | | SwissProt: | Q7RIF3_PLAYO | | TrEMBL: | | | NCBI (GI): | | | Source organism: | Plasmodium yoelii yoelii | | Sequence length: | 349 | | Percent disordered: | 25% | | Homologues: | |
| Native sequence |
10 20 30 40 50 60
| | | | | |
MAEVVNISKS ASFSKQEKEF SDFQKSKESN EKILNKESNR FTLHPIMYPE VWNFYKKAEA - 60
SFWTAEEIDL SSDLKDFEKL NVNEKHFIKH VLAFFAASDG IVLENLASKF LREVEIIEAK - 120
KFYSFQIAVE NIHSETYSLL IDNYIKDEKE RLNLFHAIEN IPAIKNKALW AAKWINDTNS - 180
FAERIVANAC VEGILFSGSF CAIFWFKKQN KLHGLTFSNE LISRDEGLHT DFNCLIYSLL - 240
ENKLPENVVQ NIVKEAVEVE RSFICESLPC DLIGMNSRLM SQYIEFVADR LLECLGCSKV - 300
FHSKNPFNWM DLISLQGKTN FFEKRVADYQ KSGVMAQRKE QVFSLNTDF
|
| Functional narrative |
Involved in deoxyribonucleoside diphosphate metabolic process, functions in ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor and transition metal ion binding.
------------------------------------------------------------------------------------------------------------------
Copyright The UniProt Consortium, http://www.uniprot.org/terms.
Distributed under the Creative Commons Attribution-NoDerivs License.
------------------------------------------------------------------------------------------------------------------
|
| Map of ordered and disordered regions |
Note: 'Mouse' over a region to see the start and stop residues. Click on a region to see detailed information.
|
| Region 1 | | Type: | Disordered | | Name: | N-terminal | | Location: | 1 - 46 | | Length: | 46 | | Region sequence: |
MAEVVNISKSASFSKQEKEFSDFQKSKESNEKILNKESNRFTLHPI | | Modification type: | Native
| | PDB: | 2P1I:A | | Structural/functional type: | Relationship to function unknown
| | Functional classes: | Unknown
| | Functional subclasses: | Unknown
| Detection methods:
- X-ray crystallography (298 K; pH: 8; Hepes 100 mM; Sodium formate 2 M)
| References:
- Wernimont, A.K., Dong, A., Choe, J., Gao, M., Walker, J., Lew, J., Alam, Z., Zhao, Y., Nordlund, P., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Artz, J.D. "Plasmodium yoelii Ribonucleotide Reductase Subunit R2 (PY03671) [XRay structure]." PDB Primary Citation. 2007.
| Comments:
|
| Region 2 | | Type: | Disordered | | Name: | C-terminal | | Location: | 310 - 349 | | Length: | 40 | | Region sequence: |
MDLISLQGKTNFFEKRVADYQKSGVMAQRKEQVFSLNTDF | | Modification type: | Native
| | PDB: | 2P1I:A | | Structural/functional type: | Relationship to function unknown
| | Functional classes: | Unknown
| | Functional subclasses: | Unknown
| Detection methods:
- X-ray crystallography (298 K; pH: 8; Hepes 100 mM; Sodium formate 2 M)
| References:
- Wernimont, A.K., Dong, A., Choe, J., Gao, M., Walker, J., Lew, J., Alam, Z., Zhao, Y., Nordlund, P., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Sundstrom, M., Bochkarev, A., Hui, R., Artz, J.D. "Plasmodium yoelii Ribonucleotide Reductase Subunit R2 (PY03671) [XRay structure]." PDB Primary Citation. 2007.
| Comments:
|
| If you have any comments or wish to provide additional references to this protein or its disordered region(s), please click here to e-mail us. |
Disprot-footer
|
