| Functional class | Description |
| Chaperones |
Help other proteins or RNA in achieving proper folded state; prevent protein aggregation; help misfolded proteins to refold. |
| Entropic chain |
Function as a result of disorder, often connecting two ordered domains and allow regulation of the distance between them. |
| Metal sponge |
Store and help remove/neutralize heavy metals for detoxification. |
| Modification site |
Permits protein modification, either by chemical additions or by protease cleavage. |
| Molecular assembly |
Assemble, regulate, and stabilize protein complexes. |
| Molecular recognition effectors |
Allow the binding of multiple partners with high specificity and low affinity, and is commonly used for signaling. |
| Molecular recognition scavengers |
Store and/or neutralize their ligands. |
| Unknown |
No experimental evidence supporting or disproving the role of the region in protein function. |
